Slight signs of an inflammatory reaction ( e.g. increases in white blood cell parameters , fibrinogen as well as changes in serum protein fractions ) were noted at the mid dose and higher .
Slight signs of an inflammatory reaction ( e.g. increases in white blood cell parameters , fibrinogen as well as changes in serum protein fractions ) were noted at the mid dose and higher .
O O O O B-FINDING I-FINDING O O B-MANIFESTATION_FINDING O B-STUDY_TESTCD I-STUDY_TESTCD I-STUDY_TESTCD O O B-STUDY_TESTCD O O O B-MANIFESTATION_FINDING O B-SPECIMEN B-STUDY_TESTCD O O O O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION I-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O