4.1 Conclusions The repeated daily administration of COMPOUND_XXX to male and female Beagle dogs over a period of 4 weeks resulted in clear signs of liver toxicity from the mid dose of 20 mg / kg COMPOUND_XXX onwards .
4.1 Conclusions The repeated daily administration of COMPOUND_XXX to male and female Beagle dogs over a period of 4 weeks resulted in clear signs of liver toxicity from the mid dose of 20 mg / kg COMPOUND_XXX onwards .
O O O O O O O O O B-SEX I-SEX I-SEX O O O O O O O O O O O O O B-FINDING I-FINDING O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O B-DOSE I-DOSE I-DOSE I-DOSE O O O