Although the expected increases in liver enzyme activities were apparent in most treated animals , the onset and progression of morphological lesions in the liver could not be followed using biopsy samples as it was not possible to collect sufficient tissue to observe such localised alterations .
Although the expected increases in liver enzyme activities were apparent in most treated animals , the onset and progression of morphological lesions in the liver could not be followed using biopsy samples as it was not possible to collect sufficient tissue to observe such localised alterations .
O O O B-FINDING I-FINDING I-FINDING I-FINDING I-FINDING O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O