The concentration for this group was not reassessed for the last 7 days of dosing and the animals given the high dose were administered , in the worst case , with a dose close to 267 mg / kg during this period .
The concentration for this group was not reassessed for the last 7 days of dosing and the animals given the high dose were administered , in the worst case , with a dose close to 267 mg / kg during this period .
O O O O O O O O O O O O O O O O O O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O O O O O O O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE O O O O