Summary of results and discussion All relevant or suspected treatment - or compound - related effects after implantation of the ELEMENT_XXX ( release rate : 5.5 μg / day COMPOUND_XXX ) can briefly be summarized as follows : Alterations in the endometrium such as atrophy and flattening of the lumenal epithelium ( by pressure ) , focal necrosis at the edges of the device and focal subepithelial hemorrhage were observed in the microscopical examination .
Summary of results and discussion All relevant or suspected treatment - or compound - related effects after implantation of the ELEMENT_XXX ( release rate : 5.5 μg / day COMPOUND_XXX ) can briefly be summarized as follows : Alterations in the endometrium such as atrophy and flattening of the lumenal epithelium ( by pressure ) , focal necrosis at the edges of the device and focal subepithelial hemorrhage were observed in the microscopical examination .
O O O O O O O O O O O O O O O O O O O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O O O O O O B-FINDING O B-FINDING O O O B-SPECIMEN O O O O O B-FINDING I-FINDING O O O O O O O B-FINDING I-FINDING I-FINDING O O O O O O O