For microscopic observations , all tissue sections from control and high - dose animals and from all unscheduled deaths / sacrifices , all gross lesions and the potential target tissues ( masseter muscle , adrenal , pituitary , kidney , lung , ovary , mesenteric lymph node , sternum , tibia - femur and harderian gland ) from all dose groups were processed .
For microscopic observations , all tissue sections from control and high - dose animals and from all unscheduled deaths / sacrifices , all gross lesions and the potential target tissues ( masseter muscle , adrenal , pituitary , kidney , lung , ovary , mesenteric lymph node , sternum , tibia - femur and harderian gland ) from all dose groups were processed .
O O O O O O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION I-DOSE_QUALIFICATION I-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-GROUP I-GROUP I-GROUP O O O