Furthermore , impaired general condition as well as changes indicative of impaired kidney and liver function were noted at the mid and high dose .
Furthermore , impaired general condition as well as changes indicative of impaired kidney and liver function were noted at the mid and high dose .
O O B-FINDING I-FINDING I-FINDING O O O B-FINDING I-FINDING I-FINDING I-FINDING I-FINDING I-FINDING I-FINDING I-FINDING O O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION I-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O