Atrophy of the pars distalis of the pituitary gland e Atrophy of the vaginal epithelium Changes observed at the end of 4 - week treatment - free recovery period : e Diffuse adrenocortical atrophy in single animals e Diffuse alveolar foam cell ( i.e. histiocytes ) aggregation ( with associated acute / mixed inflammation and hyperplasia of alveolar type II pneumocytes ) with associated minimal fibroplasias e â € " Granulomas and / or granulomatous inflammation and associated reactive lymphoid hyperplasia in the mediastinal lymph nodes of single animals Â ¢ â € " Lobuloalveolar histologic pattern in the mammary gland e Increased incidence and severity of follicular cysts in the ovaries e â € " Atrophy of the pars distalis of the pituitary gland in most animals e Atrophy of uterine horn , body and cervix e Atrophy of the epithelium of the vagina e = Thymic involution with increased lymphocytolysis in single animals is considered to be suspected compound - related
Atrophy of the pars distalis of the pituitary gland e Atrophy of the vaginal epithelium Changes observed at the end of 4 - week treatment - free recovery period : e Diffuse adrenocortical atrophy in single animals e Diffuse alveolar foam cell ( i.e. histiocytes ) aggregation ( with associated acute / mixed inflammation and hyperplasia of alveolar type II pneumocytes ) with associated minimal fibroplasias e â € " Granulomas and / or granulomatous inflammation and associated reactive lymphoid hyperplasia in the mediastinal lymph nodes of single animals Â ¢ â € " Lobuloalveolar histologic pattern in the mammary gland e Increased incidence and severity of follicular cysts in the ovaries e â € " Atrophy of the pars distalis of the pituitary gland in most animals e Atrophy of uterine horn , body and cervix e Atrophy of the epithelium of the vagina e = Thymic involution with increased lymphocytolysis in single animals is considered to be suspected compound - related
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