After a 4 - week treatment free period , compound - related microscopic changes were still present in the kidney in males ( occasional tubular cell anisokaryosis and mild tubular basophilia with peritubular fibrosis ) and in the adrenal gland in females ( increase in severity in cell vacuolation of the zona glomerulosa ) .
After a 4 - week treatment free period , compound - related microscopic changes were still present in the kidney in males ( occasional tubular cell anisokaryosis and mild tubular basophilia with peritubular fibrosis ) and in the adrenal gland in females ( increase in severity in cell vacuolation of the zona glomerulosa ) .
O O O O O O O O O O O O O O O O O O O B-SPECIMEN O B-SEX O O B-FINDING I-FINDING I-FINDING O O B-FINDING I-FINDING O B-FINDING I-FINDING O O O O B-SPECIMEN I-SPECIMEN O B-SEX O B-MANIFESTATION_FINDING O O O B-FINDING I-FINDING I-FINDING I-FINDING I-FINDING I-FINDING O O