Additional compound - related microscopic changes were present in the lymph nodes ( decreases in presence and activity of germinal centers in both sexes at doses ≥ 0.6 mg / kg ) , thymus ( lymphoid atrophy in males at 1.2 mg / kg ) and thyroid ( reduced follicular colloid with occasional instances of follicular epithelial hypertrophy in both sexes at 1.2 mg / kg ) .
Additional compound - related microscopic changes were present in the lymph nodes ( decreases in presence and activity of germinal centers in both sexes at doses ≥ 0.6 mg / kg ) , thymus ( lymphoid atrophy in males at 1.2 mg / kg ) and thyroid ( reduced follicular colloid with occasional instances of follicular epithelial hypertrophy in both sexes at 1.2 mg / kg ) .
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