User: I want to create a SMILES.
Assistant: This sounds  very curious. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be toxic in the SR-ARE assay.
Assistant: Ok, here you go, this SMILES is not toxic in the SR-ARE assay: COc1c(C(C)(C)C)cc([N+](=O)[O-])c(C)c1[N+](=O)[O-]
User: I want to create a SMILES.
Assistant: This sounds  very curious. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be toxic in the SR-ARE assay.
Assistant: Ok, here you go, this SMILES is not toxic in the SR-ARE assay: COc1c(C(C)(C)C)cc([N+](=O)[O-])c(C)c1[N+](=O)[O-]