User: I want to come up with a SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be toxic in the SR-ARE assay.
Assistant: Ok, this SMILES is not toxic in the SR-ARE assay: CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2SCC4)CC1
User: I want to come up with a SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be toxic in the SR-ARE assay.
Assistant: Ok, this SMILES is not toxic in the SR-ARE assay: CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2SCC4)CC1