User: I want to create a SMILES.
Assistant: This sounds  very curious. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be toxic in the Antioxidant response element assay.
Assistant: Ok, this SMILES is not toxic in the Antioxidant response element assay: CN1COCN(Cc2cnc(Cl)s2)C1=N[N+](=O)[O-]
User: I want to create a SMILES.
Assistant: This sounds  very curious. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be toxic in the Antioxidant response element assay.
Assistant: Ok, this SMILES is not toxic in the Antioxidant response element assay: CN1COCN(Cc2cnc(Cl)s2)C1=N[N+](=O)[O-]