User: I want to create a SMILES.
Assistant: This sounds  very curious. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be toxic in the SR-ARE assay.
Assistant: Ok, this SMILES is not toxic in the SR-ARE assay: Nc1nc(N)nc(-c2cc(Cl)ccc2Cl)n1
User: I want to create a SMILES.
Assistant: This sounds  very curious. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be toxic in the SR-ARE assay.
Assistant: Ok, this SMILES is not toxic in the SR-ARE assay: Nc1nc(N)nc(-c2cc(Cl)ccc2Cl)n1