Title: Sulfanilamide | drug | Britannica
Headings: Sulfanilamide
Sulfanilamide
drug
Learn about this topic in these articles:
antibiotic development
antimetabolites
carboxylic acids
medicinal applications
organosulfur compounds
sulfa drugs

Content: In 1936 English physician Leonard Colebrook and colleagues provided overwhelming evidence of the efficacy of both Prontosil and sulfanilamide in streptococcal septicemia (bloodstream infection), thereby ushering in the sulfonamide era. New sulfonamides, which appeared with astonishing rapidity, had greater potency, wider antibacterial range, or…
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organosulfur compounds
In organosulfur compound: Other sulfinyl and sulfonyl compounds
Sulfanilamide, p -aminobenzenesulfonamide, a compound used in the manufacture of azo dyes, was found to inhibit the growth of bacteria. This discovery led to the development of sulfa drugs, which still find some use today in the treatment of infections, although they have been largely replaced…
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sulfa drugs
In sulfa drug
…of synthetic antibiotics containing the sulfanilamide molecular structure. Sulfa drugs were the first chemical substances systematically used to treat and prevent bacterial infections in humans. Their use has diminished because of the availability of antibiotics that are more effective and safer and because of increased instances of drug resistance. Sulfonamides…
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