Title: Magnolia officinalis Supplement — Health Benefits, Dosage, Side Effects | Examine.com
Headings: Magnolia officinalis
Magnolia officinalis
Magnolia officinalis is a traditional chinese medicine known for its neuroprotective and relaxing properties, being used to treat depression and anxiety as well as acting as a slight sedative. It may also possess anti-cancer effects in higher doses.
Summary of Magnolia officinalis
Primary information, health benefits, side effects, usage, and other important details
Guidance from the experts
How to Take
Recommended dosage, active amounts, other details
Easily stay on top of the latest nutrition research
Human Effect Matrix
Stay on top of the latest research
Things to Note
Is a Form Of
Primary Function:
Also Known As
Do Not Confuse With
Goes Well With
Get our free 5-day course on the essentials of supplementation.
Research Breakdown on Magnolia officinalis
1 Sources and Composition
1.1 Sources
1.2 Composition
1.3 Structure and Properties
2 Pharmacology
2.1 Serum
2.2 Metabolism
2.3 Excretion
2.4 Neural
3 Neurology
3.1 Cholinergic Neurotransmission
3.2 GABAergic Neurotransmission
3.3 Glutaminergic Neurotransmission
3.4 Dopaminergic Neurotransmission
3.5 Adenosinergic Neurotransmission
3.6 Serotonergic Neurotransmission
3.7 Sedation
3.8 Anxiety
3.9 Stress
3.10 Depression
3.11 Menopausal Symptoms
4 Interactions with Glucose Metabolism
4.1 Mechanisms
4.2 Diabetic Nephropathy
5 Obesity and Fat Mass
5.1 Mechanisms
5.2 Weight Gain
6 Skeleton and Bone Mass
6.1 Dental Health
7 Inflammation and Immunology
7.1 Macrophages
8 Interactions with Cancer Metabolism
8.1 Mechanisms
8.2 Tumorogenesis
9 Nutrient-Nutrient Interactions
9.1 Ginger
9.2 Pinelliae Rhizome

Content: Want a deeper look at the research? Examine Members get full access to the comprehensive research database, monthly study summaries, and the latest in-depth analysis. Your support allows us to be 100% independent and unbiased. How to Take
Recommended dosage, active amounts, other details
The dosage of magnolia officinalis to take varies on goal. For those related to GABA (including anxiety, sedation, stress, and epilepsy) an oral dose of 0.2mg/kg in mice appears effective and suggests very lose doses (5-10 mg) are effective in humans. For those goals related to learning or depression, higher doses may be required. This usually means 15-30mg/kg in rats, and suggests a human dose of: 160-330 mg for a 150lb person
220-440 mg for a 200lb person
270-550 mg for a 250lb person
The above doses refer to the total neolignans (usually magnolol plus honokiol), which are usually at 1-10% of a basic bark extract unless otherwise concentrated. Easily stay on top of the latest nutrition research
Become an Examine Member to get access to the latest research. Get 150+ studies summarized for you across 25 different categories every month.