Title: Susceptibility of urine isolates of Staphylococcus saprophyticus to antimicrobial agents - ScienceDirect
Headings: 
Pathology
Susceptibility of urine isolates of Staphylococcus saprophyticus to antimicrobial agents
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Content: saprophyticus isolates whereas, in comparison, little affinity to epithelia from other body sites was found,','' explaining the apparent tropism of this organism for the urinary tract. Generally, Staph. saprophyticus is susceptible to most antimicrobial agents prescribed for patients with urinary tract infection. Some variation in susceptibility, however, has been reported, especially with tetracycline, ampicillin and the newer quinolones, particularly norflox- Plasmid analysis showed that Staph. acin. 3 ,6 -8 .1 I , 12 suphrophyticus may ha rbor plasmids encoding antimicrobial resistance12 and beta-lactamase activity has been observed in some clinical isolate^.^,'^ Because of the importance of Staph. saprophyticus as a urinary pathogen, empirical therapy should be chosen to include an antibiotic active against this organism. The purpose of this study was to determine the susceptibility of Staph. saprophyticus to a selection of antimicrobial agents likely to be used in the therapy of community- acquired urinary tract infections. MATERIALS AND METHODS Isolures All isolates of Stuph.