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Content: We know that we live on a planet that revolves around one of a hundred billion stars in our galaxy, which is one of a hundred billion galaxies in a 13.8-billion-year-old universe, possibly one of a vast number of universes. We know that our intuitions about space, time, matter, and causation are incommensurable with the nature of reality on scales that are very large and very small. We know that the laws governing the physical world (including accidents, disease, and other misfortunes) have no goals that pertain to human well-being. There is no such thing as fate, providence, karma, spells, curses, augury, divine retribution, or answered prayers—though the discrepancy between the laws of probability and the workings of cognition may explain why people believe there are. And we know that we did not always know these things, that the beloved convictions of every time and culture may be decisively falsified, doubtless including some we hold today. In other words, the worldview that guides the moral and spiritual values of an educated person today is the worldview given to us by science. Though the scientific facts do not by themselves dictate values, they certainly hem in the possibilities. By stripping ecclesiastical authority of its credibility on factual matters, they cast doubt on its claims to certitude in matters of morality. The scientific refutation of the theory of vengeful gods and occult forces undermines practices such as human sacrifice, witch hunts, faith healing, trial by ordeal, and the persecution of heretics. The facts of science, by exposing the absence of purpose in the laws governing the universe, force us to take responsibility for the welfare of ourselves, our species, and our planet.