Title: Interstitial cell of Cajal - Wikipedia
Headings: Interstitial cell of Cajal
Interstitial cell of Cajal
Contents
Role in slow wave activity
Frequency of ICC pacemaker cells
Pathology
Eponym
See also
References
External links

Content: Carbachol increases ICC activity through ANO1 activation. ICC are also critical in the propagation of electrical slow waves. ICC form a network through which slow wave activity can propagate. If this network is broken, then 2 regions of muscle will function independently. Pathology
ICCs are thought to be the cells from which gastrointestinal stromal tumours (GISTs) arise. Also, abnormalities in the ICC network is one cause of chronic intestinal pseudo-obstruction. Eponym
The interstitial cells of Cajal are named after Santiago Ramón y Cajal, a Spanish pathologist and Nobel laureate . See also
List of human cell types derived from the germ layers
Telocyte, a similar, and potentially equivalent, cell
References
^ http://www.uni-mainz.de/FB/Medizin/Anatomie/workshop/EM/EMDuodenum.html
^ Hennig GW, Spencer NJ, Jokela-Willis S, Bayguinov PO, Lee HT, Ritchie LA, Ward SM, Smith TK, Sanders KM (May 2010). " ICC-MY coordinate smooth muscle electrical and mechanical activity in the murine small intestine". Neurogastroenterol.