Title: CREST syndrome | definition of CREST syndrome by Medical dictionary
Headings: CREST syndrome
CREST syndrome
CREST syndrome
CREST syn·drome
CREST syn·drome
CREST syndrome
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CREST syn·drome
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Content: Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved. CREST syn·drome
a variant of systemic sclerosis characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia. Farlex Partner Medical Dictionary © Farlex 2012
An acronym for the pentad of clinical signs seen with a limited form of scleroderma: Calcinosis cutis
Raynaud’s phenomenon—at least a 2-phase colour change
Esophageal distal hypomotility or reflux esophagitis
Sclerodactyly or nonpitting digital edema
Telangiectasia; CREST has a slightly better prognosis than other connective tissue disorders, but has late complications—e.g., biliary cirrhosis and pulmonary hypertension
Lab Anticentromere antibodies are characteristic of CREST, but may also be seen in progressive systemic sclerosis, older women, or those with HLA-DR1
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved. CREST syn·drome
( krest sin'drōm)
An acronymic designation for a variant of scleroderma characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia. Medical Dictionary for the Health Professions and Nursing © Farlex 2012
CREST syndrome
Acronym for a connective tissue disorder, related to progressive systemic sclerosis, but limited to CALCINOSIS, RAYNAUD'S PHENOMENON, oesophageal involvement, hardness of the fingers (Sclerodactyly) and dilated skin blood vessels ( TELANGIECTASIA ).