Title: Lymphocytic colitis: clinical features, treatment, and outcomes - ScienceDirect
Headings: Lymphocytic colitis: clinical features, treatment, and outcomes
The American Journal of Gastroenterology
Original contribution
Lymphocytic colitis: clinical features, treatment, and outcomes
Abstract
Introduction
Materials and methods
Results
Clinical features
Associated conditions
Laboratory features
Treatment and response
Discussion
References

Content: Associated Autoimmune Disorders
Disorder
%
Thyroid dysfunction
21
Diabetes mellitus
10
Celiac disease
5.9
Psoriasis
5.3
Rheumatoid arthritis
2.4
Sjogren’s syndrome
2.4
Raynaud’s phenomenon
2.4
Dermatomyositis
1.7
Polymyalgia rheumatica
1.2
Mixed CTD
1.2
CREST syndrome
1.2
Wegener’s granulomatosis
0.6
Bechet’s syndrome
0.6
Systemic lupus
0.6
CREST = calcinosis, Reynaud’s phenomenon, esophageal dysmotility, sclerodactyly, telangiectasias; CTD = connective tissue disorder. Celiac sprue was present in 10 patients (6%). In three, the diagnoses of sprue and lymphocytic colitis were made simultaneously. One of these patients responded completely to a gluten-free diet, one patient had a partial response to a gluten-free diet with remission achieved after the addition of mesalamine, and one patient had no follow-up. In six patients, lymphocytic colitis was diagnosed after lack of response to a gluten-free diet (2) or because of recurrent diarrhea despite adherence to the diet (4). Of these latter six patients, four responded to therapy for lymphocytic colitis, and two had no follow-up. Finally, one patient was diagnosed with sprue after failing many therapies for lymphocytic colitis. This patient responded to a gluten-free diet. Laboratory features
For the most part, laboratory studies were normal or unremarkable.