Title: Lymphocytic colitis: clinical features, treatment, and outcomes - ScienceDirect
Headings: Lymphocytic colitis: clinical features, treatment, and outcomes
The American Journal of Gastroenterology
Original contribution
Lymphocytic colitis: clinical features, treatment, and outcomes
Abstract
Introduction
Materials and methods
Results
Clinical features
Associated conditions
Laboratory features
Treatment and response
Discussion
References

Content: Associated conditions
Autoimmune diseases occurred in 43% of these patients. Thyroid dysfunction was present in 21%, diabetes mellitus in 10%, psoriasis in 5%, and rheumatoid arthritis in 2%. Other associated autoimmune diseases reported in these patients are listed in Table 3. Four patients had a history of colon cancer, preceding the diagnosis of lymphocytic colitis by 4, 8, 10, and 25 yr. Table 3. Associated Autoimmune Disorders
Disorder
%
Thyroid dysfunction
21
Diabetes mellitus
10
Celiac disease
5.9
Psoriasis
5.3
Rheumatoid arthritis
2.4
Sjogren’s syndrome
2.4
Raynaud’s phenomenon
2.4
Dermatomyositis
1.7
Polymyalgia rheumatica
1.2
Mixed CTD
1.2
CREST syndrome
1.2
Wegener’s granulomatosis
0.6
Bechet’s syndrome
0.6
Systemic lupus
0.6
CREST = calcinosis, Reynaud’s phenomenon, esophageal dysmotility, sclerodactyly, telangiectasias; CTD = connective tissue disorder. Celiac sprue was present in 10 patients (6%). In three, the diagnoses of sprue and lymphocytic colitis were made simultaneously. One of these patients responded completely to a gluten-free diet, one patient had a partial response to a gluten-free diet with remission achieved after the addition of mesalamine, and one patient had no follow-up.