Title: Trimethoprim/sulfamethoxazole - Wikipedia
Headings: Trimethoprim/sulfamethoxazole
Trimethoprim/sulfamethoxazole
Trimethoprim/sulfamethoxazole
Contents
Medical uses
Susceptibility
Pregnancy and breast feeding
Babies
Adverse effects
Contraindications
Interactions
Overdose
Pharmacology
Society and culture
Approval
Indications for co-trimoxazole
Route
Trade names
Cost
References
External links

Content: POM (Prescription only)
US: ℞-only
Identifiers
CAS Number
738-70-5
Y
723-46-6
Y
PubChem CID
358641
DrugBank
DB01015
DB00440
ChemSpider
318412
UNII
JE42381TNV
AN164J8Y0X
Y
ChEBI
CHEBI:3770
CompTox Dashboard (EPA)
DTXSID0032233
(verify)
Trimethoprim/sulfamethoxazole ( TMP/SMX ), also known as co-trimoxazole among other names, is an antibiotic used to treat a variety of bacterial infections. It consists of one part trimethoprim to five parts sulfamethoxazole. It is used for urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. It may be used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in people with HIV/AIDS and other causes of immunosuppression. It can be given by mouth or intravenously. Common side effects include nausea, vomiting, rash, and diarrhea. Severe allergic reactions and Clostridium difficile infection may occasionally occur. Its use in pregnancy is not recommended. It appears to be safe for use during breastfeeding as long as the baby is healthy.