Title: Staphylococcus saprophyticus: Which beta-lactam? - ScienceDirect
Headings: Staphylococcus saprophyticus
: Which beta-lactam?

International Journal of Infectious Diseases
Short Communication
Staphylococcus saprophyticus: Which beta-lactam?
Highlights
Abstract
Background
Methods
Results
Conclusions
Keywords
Introduction
Methods
Results
Discussion
Conflict of interest/funding
References

Content: Most urine samples (92.8%) were collected in the emergency departments of the hospital. Leukocyte counts in the urine >104/ml and the presence of Gram-positive cocci were recorded for most of the urine samples infected with MSSS (92.8% and 65.9%, respectively). The clinical symptoms recorded for the patients corresponded to cystitis (59.5%), pyelonephritis (33.3%), abdominal pain (6.0%), and prostatitis (1.2%). Finally, the empirical antibiotic therapy administered to the patients was analysed. In this study, 60% of patients with a diagnosis of cystitis were given an inappropriate antibiotic regimen (cefixime, fosfomycin, or amoxicillin), whereas the rate was 25% for those with a diagnosis of pyelonephritis (amoxicillin and cefixime). The MICs of ceftriaxone and amoxicillin–clavulanic acid were analysed for the MSSS and MSSA isolates. With the gradient test method, the MICs of ceftriaxone ranged from 4 to >32 μg/ml for MSSS, and from 1.5 to 4 μg/ml for MSSA. The MICs of amoxicillin–clavulanic acid ranged from 0.25 to 2 μg/ml for MSSS and from 0.5 to 2 μg/ml for MSSA ( Figure 1 ). With the broth microdilution method, the MICs of ceftriaxone ranged from 2 to 32 μg/ml for MSSS, and from 2 to 4 μg/ml for MSSA. The MICs of amoxicillin–clavulanic acid were all <1 μg/ml for MSSS and MSSA isolates with the broth microdilution method ( Figure 2 ).