Title: Staphylococcus saprophyticus- An Overview | Microbe Notes
Headings: Staphylococcus saprophyticus- An Overview
Staphylococcus saprophyticus- An Overview
Table of Contents
What is Staphylococcus saprophyticus?
Classification of Staphylococcus saprophyticus
Habitat of Staphylococcus saprophyticus
Morphology of Staphylococcus saprophyticus
Cultural Characteristics of Staphylococcus saprophyticus
1. Nutrient Agar (NA)
2. Mannitol Agar
3. Blood agar (BA)
4. P agar
5. Thioglycolate medium
Biochemical characteristics of Staphylococcus saprophyticus
Fermentation
Enzymatic Reactions
Virulence factors of Staphylococcus saprophyticus
1. Surface proteins
2. Enzymes
3. Biofilm formation
Pathogenesis of Staphylococcus saprophyticus
1. Adhesion/ Attachment/ Colonization
2. Invasion
Catheters-related infections
Clinical manifestations of Staphylococcus saprophyticus
Lab Diagnosis of Staphylococcus saprophyticus
1. Morphological characteristics and Biochemical tests
2. Rapid Identification kits
3. Molecular diagnosis
Treatment of Staphylococcus saprophyticus infection
Prevention of Staphylococcus saprophyticus infection
References
Sources

Content: Staphylococcus saprophyticus is a Gram-positive, coagulase-negative coccus that is an important part of the group of microorganisms causing urinary tract infections (UTIs), particularly in young sexually active females. Like all Staphylococci, S. saprophyticus is also clustering Gram-positive cocci, nonmotile, non-spore-forming, and facultatively anaerobic. S. saprophyticus is a part of the normal flora in humans that colonizes the areas like the perineum, rectum, urethra, cervix, and gastrointestinal tract. This bacterium is also a common gastrointestinal flora in pigs and cows and may be transferred to humans by eating these respective foods. Besides humans, it can also be isolated from other environmental sources like meat and dairy products. It is the second most common cause of UTIs in young and middle-aged women, next to Escherichia coli. Less commonly, it is also responsible for complications like acute pyelonephritis, urethritis, epididymitis, and prostatitis. Among staphylococci, S. saprophyticus is the only species that is typically uropathogenic which is due to its ability to adhere to uroepithelial cells and persistently grow in the urinary tract. S. saprophyticus is different from S. aureus in that it is coagulase-negative, meaning it lacks the enzyme coagulase. It can be differentiated from other coagulase-negative staphylococci by its resistance to Novobiocin.