Title: Muscle Membrane, T Tubules, and Sarcoplasmic Reticulum | Neupsy Key
Headings: Muscle Membrane, T Tubules, and Sarcoplasmic Reticulum
Muscle Membrane, T Tubules, and Sarcoplasmic Reticulum
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Content: Muscle Membrane, T Tubules, and Sarcoplasmic Reticulum | Neupsy Key
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NEUROLOGY
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More References »
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Musculoskeletal Key
Neupsy Key
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Showing most revelant items. Click here or hit Enter for more. Muscle Membrane, T Tubules, and Sarcoplasmic Reticulum
T tubules are specialized invaginations of the sarcolemma, with which it is continuous at multiple points. T tubules run transverse to the muscle fibers themselves and the sarcolemma and encircle individual muscle fibrils. T tubules form deep invaginations into the sarcolemma. This provides not only more rapid dispersal of muscle membrane depolarization along the muscle fiber, but it allows for propagation along both the surface of the sarcolemma and into the muscle fiber, where it can interact with deep sarcoplasmic reticulum. T tubules interact directly with components of the sarcoplasmic reticulum, leading to Ca 2+ release into the sarcoplasm. They also harbor voltage-gated Ca 2+ channels, L-type Ca 2+ channels. These Ca 2+ channels do not contribute to depolarization or the muscle fiber action potential but, rather, act as voltage sensors of muscle membrane depolarization. The sarcoplasmic reticulum forms a network of tubules surrounding muscle fibrils inside the sarcolemma.