Title: Genetic Effects on Toxic and Essential Elements in Humans: Arsenic, Cadmium, Copper, Lead, Mercury, Selenium, and Zinc in Erythrocytes | Environmental Health Perspectives | Vol. 118, No. 6
Headings: Genetic Effects on Toxic and Essential Elements in Humans: Arsenic, Cadmium, Copper, Lead, Mercury, Selenium, and Zinc in Erythrocytes
Genetic Effects on Toxic and Essential Elements in Humans: Arsenic, Cadmium, Copper, Lead, Mercury, Selenium, and Zinc in Erythrocytes
Abstract
Background and objectives
Methods
Results
Conclusions
Materials and Methods
Participants
Laboratory procedures
Data analysis
Effects of covariates
Genetic and environmental sources of variation
Linkage analysis
Empirical genome-wide thresholds
Results
Covariate effects
Element correlations
Sources of variation and covariation
Linkage analysis
Discussion
Subject characteristics and socioeconomic effects
Genetic influences
Localization of genes by linkage analysis
Strengths and limitations
Conclusions

Content: 2007) and renal ( Hodgson et al. 2007) disease have been associated with low-level Hg exposure. For Pb, the main concerns have been about impaired intellectual development in infancy and childhood ( Canfield et al. 2003; Needleman 2004; Pocock et al. 1994; Schwartz 1994 ), but adult cognitive function may also be affected ( Schwartz and Hu 2007; Shih et al. 2007 ).