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Content: Less commonly, it is responsible for complications including acute pyelonephritis, urethritis, epididymitis, and prostatitis. An acute uncomplicated UTI is characterized by dysuria and frequency in an immunocompetent, non-pregnant adult female and is the most common bacterial infection in women. A complicated infection typically involves a patient that is immunocompromised, elderly, male, pregnant, diabetic, and/or with urologic abnormalities such as indwelling catheters or kidney disease. S. saprophyticus can be differentiated from another coagulase-negative staphylococcus by its resistance to Novobiocin. Like other uropathogens, S. saprophyticusutilizes urease to produce ammonia. However, unlike many of these organisms, it cannot reduce nitrate. S. saprophyticusis part of the normal human flora that colonizes the perineum, rectum, urethra, cervix, and gastrointestinal tract. It has also been found that S. saprophyticus is a common gastrointestinal flora in pigs and cows and thus may be transferred to humans through eating these respective foods. Copyright © 2021, StatPearls Publishing LLC. Sections
    
Continuing Education Activity
      
Introduction
      
Etiology
      
Epidemiology
      
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