Title: CREST syndrome - Wikipedia
Headings: CREST syndrome
CREST syndrome
Contents
Signs and symptoms
Calcinosis
Raynaud's phenomenon
Esophageal dysmotility
Sclerodactyly
Telangiectasias
Other
Cause
Diagnosis
Treatment
Epidemiology
History
See also
References
External links

Content: CREST syndrome - Wikipedia
CREST syndrome
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Medical condition
CREST syndrome
Other names
Calcinosis-Raynaud phenomenon-esophageal involvement-sclerodactyly-telangiectasia syndrome

CREST syndrome (calcinosis and sclerodactyly)
Specialty
Rheumatology
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder. The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. CREST syndrome is associated with detectable antibodies against centromeres (a component of the cell nucleus ), and usually spares the kidneys (a feature more common in the related condition systemic scleroderma ). If the lungs are involved, it is usually in the form of pulmonary arterial hypertension . Contents
1 Signs and symptoms
1.1 Calcinosis
1.2 Raynaud's phenomenon
1.3 Esophageal dysmotility
1.4 Sclerodactyly
1.5 Telangiectasias
1.6 Other
2 Cause
3 Diagnosis
4 Treatment
5 Epidemiology
5.1 History
6 See also
7 References
8 External links
Signs and symptoms
CREST syndrome (calcinosis and sclerodactyly)
X-rays showing calcinosis in a woman with CREST syndrome.