Title: Lab Test: White Blood Cell Count, WBC
Headings: 
Lab Test: White Blood Cell Count, WBC
Lab Test
Description
Reference Range
Indications & Uses
Clinical Application
Drug-Lab Interactions
Test Tube Needed
Procedure
Storage and Handling
What To Tell Patient Before & After
References
MESH Terms & Keywords

Content: Initial evaluation of suspected hyperglycemic hyperosmolar state (HHS)
The majority of patients with HHS present with leukocytosis proportional to the blood ketone body concentration. The majority of patients present with WBC counts in the 10,000 to 15,000/mm3 range without a left shift; counts >25,000/mm3 with a left shift suggest bacterial infection. Known or suspected hematological malignancies
Patients with primary bone marrow disorders (e.g., leukemia or myeloproliferative disorders) often preset with extreme leukocytosis. In acute myelogenous leukemia (AML), WBC counts are usually above 15,000/microL and maybe as high as 1 million cells/mm3; rarely, neutropenia is observed. Fewer than 15% of patients have WBC counts <100,000 cells/microL. These findings are usually associated with anemia and thrombocytopenia. In chronic myelogenous leukemia (CML), a WBC count between 30,000 and 400,000/microL is frequently seen, associated with thrombocytosis, mild-to-moderate anemia, and splenomegaly. Hyperleukocytosis at the time of diagnosis is most frequently seen in patients with CML. In patients with myelogenous or lymphocytic leukemia, signs of pulmonary infiltration (dyspnea, tachypnea, and hypoxia) may be associated with high blast cell counts (WBC counts above 100,000 cells/microL).