Title: 
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Content: StatPearls Publishing; 2021 Jan.
2020 Jun 28. Authors
          
Sarah Ehlers 1
              , Stefan A. Merrill 1
              
Affiliation
          
1Kingman Regional Medical Center
PMID: 29493989
    
Bookshelf ID: NBK482367
    
Excerpt
        
      
Staphylococcus saprophyticusis a Gram-positive, coagulase negative, non-hemolytic coccus that is a common cause of uncomplicated urinary tract infections (UTIs), particularly in young sexually active females. Less commonly, it is responsible for complications including acute pyelonephritis, urethritis, epididymitis, and prostatitis. An acute uncomplicated UTI is characterized by dysuria and frequency in an immunocompetent, non-pregnant adult female and is the most common bacterial infection in women. A complicated infection typically involves a patient that is immunocompromised, elderly, male, pregnant, diabetic, and/or with urologic abnormalities such as indwelling catheters or kidney disease. S. saprophyticus can be differentiated from another coagulase-negative staphylococcus by its resistance to Novobiocin. Like other uropathogens, S. saprophyticusutilizes urease to produce ammonia.