Title: Who Are You—Staphylococcus saprophyticus? | Clinical Infectious Diseases | Oxford Academic
Headings: Who Are You—
Staphylococcus saprophyticus?

Who Are You— Staphylococcus saprophyticus?
Published:
Abstract
Acknowledgments
References

Content: Topic: urinary tract infections
cystitis
signs and symptoms
escherichia coli
microorganisms
staphylococcus saprophyticus
seasonal variation
Issue Section: BRIEF REPORTS
Staphylococcus saprophyticus is uniquely associated with uncomplicated urinary tract infection (UTI) in humans. It has special urotropic and ecologic features that are distinctly different from other staphylococci and from Escherichia coli. This article will consider the epidemiology, ecology, pathogenesis, and clinical features of infections caused by this microorganism. Much more needs to be learned about the epidemiology and natural history of UTI caused by S. saprophyticus as well as the role of S. saprophyticus in human and animal health and disease. A series of research questions are offered to address these issues. Coagulase-negative staphylococci were considered to be urinary contaminants prior to the 1960s. In 1962, Torres Pereira [ 1] reported the isolation of coagulase-negative staphylococci possessing antigen 51 from the urine of women with acute UTI. In subsequent years, additional reports supported this concept [ 2 ].