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Content: Endogenous
What is the predominate species of GNB in the colonic flora? E. coli
Urine dipstick results = Gram neg rods, + nitrates, + lactose, + indole, - oxidase. Name the organism
E. coli
What virulence factor of E. coli is responsible for cystitis? Type 1 fimbriae
What virulence factor of E. coli is responsible for pyelonephritis? P fimbriae
Name the virulence factors of E. coli
Type 1 fimbriae, P fimbriae
Hemolysins, aerobactin
Resistance to serum killing, capsule, IBC formation
Antibiotic resistance a problem
What organism is typically present in UTI in newly sexually active women? S. saprophyticus
What organism ALWAYS tests nitrate negative on urine dipstick? S. saprophyticus
In patient w/ a urine pH >7, what should we culture for? Proteus mirabilis
What are the virulence factors we see in proteus mirabilis? Biofilms and encrustations on catheters
Urease -> Increase pH -> renal calculi, catheter
What organism do we suspect in UTIs in patients w/ structural abnormalities or catheters (particularly long term indwelling)? Proteus mirabilis
What organism do we see swarming mobility on culture?