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Content: Co-trimoxazole is also used in the treatment of mild cases of lower urinary tract infections in children. Co-trimoxazole is used as a second-line antibiotic to treat the following infections: Acute exacerbations of chronic bronchitis
Adult pneumonia
Childhood otitis media
Sinusitis
Cellulitis
Diabetic foot complications
Salmonellosis
Acute pyelonephritis
Patients who do not respond well to antibiotics as their first-line treatment should be tested for the presence of MRSA if they have an infected surgical or non-healing wound. Sulfonamide antibiotics can be used as a second-line treatment. SIDE EFFECTS
Sulfonamide antibiotics have been known to cause sun sensitivity leading to severe sunburn. Patients should avoid prolonged sun exposure and should apply sunscreen. Although rare, anemia, low platelet count (thrombocytopenia), low white blood cell count (leucopenia) and liver damage can occur. It is important to drink a lot of water to avoid urinary crystals. CONTRAINDICATIONS
Sulfonamide antibiotics should be avoided in those with severe hepatic damage or prior hypersensitivity reactions. Agranulocytosis, bone marrow depression and severe renal impairment are also contraindications of co-trimoxazole.