Title: Sulfonamide (drug) - Simple English Wikipedia, the free encyclopedia
Headings: Sulfonamide (drug)
Sulfonamide (drug)
Contents
How they work
History
How they are made
References

Content: They are credited with saving the lives of tens of thousands of patients, including Franklin Delano Roosevelt, Jr. (son of President Franklin Delano Roosevelt) (in 1936) and Winston Churchill. Sulfa had a central role in preventing wound infections during the war. American soldiers were issued a first-aid kit containing sulfa pills and powder, and were told to sprinkle the powder on any open wound. Many thousands of molecules containing the sulfanilamide structure have been created since its discovery (by one account, over 5,400 permutations by 1945). They have greater effectiveness and less toxicity. Sulfa drugs are still widely used for conditions such as acne and urinary tract infections. They are back in favour for use on infections caused by bacteria resistant to other antibiotics. How they are made
Sulfonamides are prepared by the reaction of a sulfonyl chloride with ammonia or an amine . References
↑ "Sulfonamide Class Antibiotics". ↑ Kent, Michael (2000).