Title: Inherited Diseases: Types, Causes and Symptoms
Headings: What Are Inherited Diseases (Genetic Disorders)?
What Are Inherited Diseases (Genetic Disorders)?
Table of Contents
What exactly are genes?
Chromosomal aberrations or abnormalities
1. Aneuploidy
a. Down Syndrome
b. Turner syndrome
2. Deletion
3. Inversion
4. Translocation
a. Balanced translocation
b. Robertsonian translation:
Single Gene disorders
a. Achondroplasia
b. Marfan Syndrome
c. Cystic fibrosis
d. Sickle cell disease
e. Tay-Sachs disease
X-linked disorders
a. Duchenne Muscular Dystrophy
b. Haemophilia
Multifactorial diseases
a. Alzheimer’s disease
Mitochondrial genetic inheritance
a. Leber’s Hereditary Optic Atrophy
b. Myoclonic Epilepsy with ragged red fibres
In conclusion:
Sources:

Content: Research has shown that most parents are known as carriers and this is because they have one copy of an abnormal gene and one copy of a normal gene, hence the disorder is not expressed in them. However, they carry the defective gene which will be passed on to their child hence increasing the chances of inherited diseases in their offspring. Having understood what inherited diseases are and how they are passed on to their offspring, there are some types of inherited diseases that you must know about. They include
Chromosomal aberrations or abnormalities
Single gene defects
Multifactorial problems
Teratogenic disorders
Chromosomal aberrations or abnormalities
These abnormalities are diseases that are gotten as a result of malformations on any of the chromosomes. These abnormalities may occur as a result of inheritance or as a result of a spontaneous change on the DNA of the offspring. This means that there may or may not be any family history that is related to this disorder. These disorders include
1. Aneuploidy
This occurs when a child has fewer or much more chromosomes than the normal number. Examples of aneuploidy include: a. Down Syndrome
Down syndrome is one of the most common inherited diseases that we see all around us.