Title: Gram-positive uropathogens: Empirical treatment and emerging antimicrobial resistance
Headings: 
Gram-positive uropathogens: Empirical treatment and emerging antimicrobial resistance
Abstract
Key words
Abbreviations
Introduction
Methods and materials
Data collection
Study design and specimen collection
Bacterial isolation and identification
Antimicrobial sensitivity assessment
Detection of β-lactamase and quinolone-resistant genes
Statistical analyses
Results
Demographics of the study population
Isolation and identification of gram-positive UTI pathogens
Antimicrobial resistance pattern of the UTI gram-positive isolates
Antibiotic resistant genes in gram-positive uropathogens
Discussion
Ethics statement
Acknowledgments
Disclosure
References
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Content: MHA: Muller Hinton Agar; PBS: Phosphate Buffered Saline; UTI: Urinary Tract Infection
Introduction
Urinary tract infection (UTI) is one of the most common infectious diseases. The major causative agents of UTIs are Escherichia coli and other Enterobacteriaceae. The remaining proportions are associated with a variety of organisms, including the Gram-positive bacteria Staphylococcus saprophyticus, Enterococcus faecalis, Streptococcus agalactiae (group B Streptococcus, GBS), and other less frequently isolated organisms [1-3]. Most prevalent gram-positive uropathogenic bacteria include Staphylococcus saprophyticus and Enterococcus facecalis [4-6]. Gram-positive uropathogens were reported in multiple countries in both uncomplicated and complicated UTI [7-9].