Title: Transverse Tubular System - an overview | ScienceDirect Topics
Headings: Transverse Tubular System
Transverse Tubular System
Cardiovascular Physiology
Transverse Tubules
Ion Channel Trafficking
T-Tubules
Functional Organization of Vertebrate Plasma Membrane
2.4 T-tubules, physiology, and disease
Skeletal Muscle
T-tubules Are Surface Invaginations; the SR Is an Internal Membrane System
Cardiac Rhythm
4.2.1 Ca++ Regulation
Cardiovascular Physiology
Membrane Depolarization and Activator Calcium
Structure and Function of Calcium Release Channels
2 T Tubules and CRUs Revert to More Primitive Forms Under Pathological Conditions
Ion Channel Trafficking in the Heart
Ca V 1.2 Channel Trafficking in the Heart
Ca V 1.2 Forward Trafficking in Normal Heart Physiology
Ca V 1.2 Forward Trafficking in Heart Pathophysiology
Accessory Proteins Involved in Ca V 1.2 Targeted Delivery
T-Tubules and Ca V 1.2 Regulation in Normal Heart Physiology
T-Tubules and Ca V 1.2 Regulation in Heart Pathophysiology
Ca V 1.2 Internalization
Muscles
Coupling Action Potentials to Contraction
Skeletal Muscle Excitability
AIII Further Evidence that the T-Tubules Fire Na + -Dependent AP s

Content: Transverse Tubular System - an overview | ScienceDirect Topics
Transverse Tubular System
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Cardiovascular Physiology
Duncan de Souza, ... Victor C. Baum, in Smith's Anesthesia for Infants and Children (Eighth Edition), 2011
Transverse Tubules
Transverse tubules, or T-tubules, invaginations of the sarcolemma in ventricular, but not atrial, myocardial cells have been mentioned in the discussion of myocardial performance. They allow transmission of the action potential, with its attendant ion shifts, to all parts of the cell, which allows rapid activation of the entire cell. T-tubules are thus a required component of larger cells ( Gotoh, 1983 ). Maturation of T-tubules is associated with the increased size of mature myocardial cells, with the sarcolemmal calcium channels further from the contractile apparatus. Species that have a relatively mature myocardium at birth have well-developed T-tubules at birth, whereas animals with immature myocardium at birth do not. T-tubules first appear at about 30 weeks gestation in humans ( Kim et al., 1992 ). View chapter Purchase book
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URL: https://www.sciencedirect.com/science/article/pii/B9780323066129000043
Ion Channel Trafficking
T.T. Hong, R.M. Shaw, in Ion Channels in Health and Disease, 2016
T-Tubules
T-tubule membrane is associated with a unique set of ion channels supported by membrane structural subdomains. 23 Immunocytochemistry and patch clamp data indicate that 80% of the sarcolemma LTCCs are concentrated at T-tubules.