Title: sulfa drug | Infoplease
Headings: sulfa drug
sulfa drug
Content: Since sulfanilamide first came into use, more than 150 different derivatives have appeared on the market, chemically modified to achieve more effective antibacterial activity, wider spectrum of microorganisms affected, or more prolonged action. Because of their low cost they are still used in many parts of the world. However, resistance to sulfa drugs has emerged among many microorganisms, especially streptococci, meningococci, and shigella, making them less effective than formerly (see drug resistance ). The substances are still used to treat some urinary tract infections, leprosy, and in combination with other drugs, some fungal diseases and toxoplasmosis. The Columbia Electronic Encyclopedia, 6th ed. Copyright 2012, Columbia University Press. All rights reserved. See more Encyclopedia articles on: Pharmacology
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