Title: Susceptibility of urine isolates of Staphylococcus saprophyticus to antimicrobial agents - ScienceDirect
Headings: 
Pathology
Susceptibility of urine isolates of Staphylococcus saprophyticus to antimicrobial agents
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Content: '-3 It appears to be the only CNS that displays any primary pathogenicity at these and is recognized in most communities as the second most common cause of urinary tract infection (UTI), after Escherichiu coli in non-hospitalized females of child bearing age.'. "7 Largely due to its frequency in this age group, sexual transmission has been postulated,"." however, clear evidence supporting this is l a ~ k i n g . ' , ~ . ~ A high level of adherence to uroepithelium has been demonstrated i n Staph. saprophyticus isolates whereas, in comparison, little affinity to epithelia from other body sites was found,','' explaining the apparent tropism of this organism for the urinary tract. Generally, Staph. saprophyticus is susceptible to most antimicrobial agents prescribed for patients with urinary tract infection. Some variation in susceptibility, however, has been reported, especially with tetracycline, ampicillin and the newer quinolones, particularly norflox- Plasmid analysis showed that Staph. acin.