Title: Staphylococcus saprophyticus - Wikipedia
Headings: Staphylococcus saprophyticus
Staphylococcus saprophyticus
Contents
History
Epidemiology and pathogenesis
Clinical features
Laboratory diagnosis
Treatment
Different subspecies
References
External links

Content: Contents
1 History
2 Epidemiology and pathogenesis
3 Clinical features
4 Laboratory diagnosis
5 Treatment
6 Different subspecies
7 References
8 External links
History
S. saprophyticus was not recognized as a cause of urinary tract infections until the early 1970s, more than 10 years after its original demonstration in urine specimens. Prior to this, the presence of coagulase -negative staphylococci (CoNS) in urine specimens was dismissed as contamination. Epidemiology and pathogenesis
In humans, S. saprophyticus is found in the normal flora of the female genital tract and perineum. It has been isolated from other sources, too, including meat and cheese products, vegetables, the environment, and human and animal gastrointestinal tracts. S. saprophyticus causes 10–20% of urinary tract infections (UTIs). In females 17–27 years old, it is the second-most common cause of community-acquired UTIs, after Escherichia coli. Sexual activity increases the risk of S. saprophyticus UTIs because bacteria are displaced from the normal flora of the vagina and perineum into the urethra. Most cases occur within 24 hours of sex, earning this infection the nickname "honeymoon cystitis". S. saprophyticus has the capacity to selectively adhere to human urothelium. The adhesin for S. saprophyticus is a lactosamine structure.