Title: Staphylococcus saprophyticus- An Overview | Microbe Notes
Headings: Staphylococcus saprophyticus- An Overview
Staphylococcus saprophyticus- An Overview
Table of Contents
What is Staphylococcus saprophyticus?
Classification of Staphylococcus saprophyticus
Habitat of Staphylococcus saprophyticus
Morphology of Staphylococcus saprophyticus
Cultural Characteristics of Staphylococcus saprophyticus
1. Nutrient Agar (NA)
2. Mannitol Agar
3. Blood agar (BA)
4. P agar
5. Thioglycolate medium
Biochemical characteristics of Staphylococcus saprophyticus
Fermentation
Enzymatic Reactions
Virulence factors of Staphylococcus saprophyticus
1. Surface proteins
2. Enzymes
3. Biofilm formation
Pathogenesis of Staphylococcus saprophyticus
1. Adhesion/ Attachment/ Colonization
2. Invasion
Catheters-related infections
Clinical manifestations of Staphylococcus saprophyticus
Lab Diagnosis of Staphylococcus saprophyticus
1. Morphological characteristics and Biochemical tests
2. Rapid Identification kits
3. Molecular diagnosis
Treatment of Staphylococcus saprophyticus infection
Prevention of Staphylococcus saprophyticus infection
References
Sources

Content: It is the second most common cause of UTIs in young and middle-aged women, next to Escherichia coli. Less commonly, it is also responsible for complications like acute pyelonephritis, urethritis, epididymitis, and prostatitis. Among staphylococci, S. saprophyticus is the only species that is typically uropathogenic which is due to its ability to adhere to uroepithelial cells and persistently grow in the urinary tract. S. saprophyticus is different from S. aureus in that it is coagulase-negative, meaning it lacks the enzyme coagulase. It can be differentiated from other coagulase-negative staphylococci by its resistance to Novobiocin. It was first isolated from humans by Shaw in 1951, and Torres Pereira first identified its connection with UTIs in 1962. Classification of Staphylococcus saprophyticus
Classification of different species of the genus Staphylococci is based on various factors ranging from morphology, chemical properties, amino acid sequences, biochemical characteristics, and nucleotide sequences. Staphylococcus spp. are primarily classified on the basis of DNA–DNA hybridization where members of the same species demonstrate relative DNA-binding values of generally 70 percent or greater. Staphylococcal subspecies, in turn, have been identified on the basis of phenotypic characters and DNA relatedness, and ribotyping.