Title: CREST syndrome: MedlinePlus Medical Encyclopedia Image
Headings: CREST syndrome
COVID-19 Information
CREST syndrome
Overview
Was this page helpful?

Content: CREST syndrome: MedlinePlus Medical Encyclopedia Image
COVID-19 Information
x
Get the latest public health information from CDC
Get the latest research information from NIH | Español
Learn more about COVID-19 and you from HHS
You Are Here: Home →
Medical Encyclopedia →
CREST syndrome
URL of this page: //medlineplus.gov/ency/imagepages/19507.htm
CREST syndrome
Overview
The symptoms involved in CREST syndrome are associated with the generalized form of the disease Systemic sclerosis (scleroderma). CREST is an acronym for the clinical features that are seen in a patient with this disease. The "C" stands for calcinosis, where calcium deposits form under the skin on the fingers or other areas of the body. The "R", stands for Raynaud's phenomenon, spasm of blood vessels in the fingers or toes in response to cold or stress. The "E" represents esophageal dysmotility, which can cause difficulty in swallowing. The "S" is for sclerodactyly, tightening of the skin causing the fingers to bend. Finally, the letter "T" is for telangiectasia, dilated vessels on the skin of the fingers, face, or inside of the mouth.