Title: Pasteurella multocida - Wikipedia
Headings: Pasteurella multocida
Pasteurella multocida
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Contents
History
Disease
Virulence, culturing, and metabolism
Diagnosis and treatment
Current research
References
External links

Content: Current research
P. multocida mutants are being researched for their ability to cause diseases. In vitro experiments show the bacteria respond to low iron. Vaccination against progressive atrophic rhinitis was developed by using a recombinant derivative of P. multocida toxin. The vaccination was tested on pregnant gilts (female swine without previous litters). The piglets born to treated gilts were inoculated, while the piglets born to unvaccinated mothers developed atrophic rhinitis. Other research is being done on the effects of protein, pH, temperature, sodium chloride (NaCl), and sucrose on P. multocida development and survival in water. The research seems to show the bacteria survive better in 18 °C (64 °F) water compared to 2 °C (36 °F) water. The addition of 0.5% NaCl also aided bacterial survival, while the sucrose and pH levels had minor effects, as well. Research has also been done on the response of P. multocida to the host environment. These tests use DNA microarrays and proteomics techniques.