Title: Ebola virus disease
Headings: Ebola virus disease
Ebola virus disease
Key facts
Transmission
Symptoms
Diagnosis
Treatment
Vaccines
Prevention and control
Controlling infection in health-care settings
Care for people who recovered from EVD
WHO response
Table: Chronology of previous Ebola virus disease outbreaks

Content: A global stockpile of the Ervebo vaccine has become available starting January 2021. In May 2020, the European Medicines Agency recommended granting marketing authorization for a 2-component vaccine called Zabdeno-and-Mvabea for individuals 1 year and older. The vaccine is delivered in 2 doses: Zabdeno is administered first and Mvabea is given approximately 8 weeks later as a second dose. This prophylactic 2-dose regimen is therefore not suitable for an outbreak response where immediate protection is necessary. Prevention and control
Good outbreak control relies on applying a package of interventions, including case management, surveillance and contact tracing, a good laboratory service, safe burials and social mobilisation. Community engagement is key to successfully controlling  outbreaks. Raising awareness of risk factors for Ebola infection and protective measures (including vaccination) that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: Reducing the risk of wildlife-to-human transmission from contact with infected fruit bats, monkeys, apes, forest antelope or porcupines and the consumption of their raw meat.