Great question! 

Absolute indications for #Tolvaptan: 

ADPKD with eGFR ≥25 ml/min/1.73m² AND rapid progression (Mayo class 1C-1E    OR eGFR decline ≥3 ml/min/yr). 

Not all ADPKD patients qualify—careful selection is key 

#KDIGO 2025 guidelines! #Nephrology #ADPKD
#Tolvaptan #KDIGO #Nephrology #ADPKD