The blue chip index of US stocks remained above the 20,000 mark at 20,093.72 but fell 7.19 points.
Lower than expected GDP growth for the fourth quarter dampened sentiment.
Chevron, the US oil giant, also weighed on the index after releasing lower than expected quarterly results which sent its shares down 2.3% to $113.79.
Microsoft led the risers to close up 2.3% at $65.78.
The S&P 500 fell 1.99 points to 2,294.69 while the technology-heavy Nasdaq rose 5.61 points to 5,660.78.
The Dow Jones industrial average gave up early gains to finish the day lower.