The victim was found with serious injuries at a house in Unsworth Way in Oldham, Greater Manchester, at about 19:50 GMT on Thursday.
He was taken to hospital and died a short time later. Details of his injuries have not yet been revealed.
The house was cordoned off while police carried out an investigation. A 58-year-old woman has been taken into custody for questioning.
A woman has been arrested on suspicion of murdering a 56-year-old man.