Hugh Cushnaghan, 63, from Irvine in Scotland, is due before Preston Magistrates Court on Tuesday, Lancashire Police said.
The un-named victim was found with a stab wound following reports of an altercation at a property in Fishwick Parade, Preston on Sunday morning.
He was taken to hospital, but died a short time later.

A police cordon has been set up at a lane near Broad Street, following the incident at about 04:00 BST.
Police have arrested two men aged 29 and 42.
Officers are appealing for witnesses to come forward.
A man has been charged with murdering a 50-year-old man who died following a stabbing in Lancashire.
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A 27-year-old man has died following a disturbance in Barry, South Wales Police have said.