The charges relate to a 20-year-old from Slovakia allegedly sold by a gang in Greater Manchester who organised a marriage to a man facing deportation.
The five will appear before Rochdale and Bury magistrates on Friday.
Police said immigration services had also dealt with three men for overstaying their visas.
Mohammed Ali, 40, and Hateji Yakuyb, 57, both of Ashfield Road, Rochdale, Anna Cicakova, 34, and Malik Ramzan, 27, both of Wesley Street, Failsworth, and Rehman Ghani, 39, of St Heliers Drive, Cheetham Hill, have all been charged with conspiracy to hold another person in slavery or servitude and conspiracy to intentionally arrange or facilitate entry into the UK of a person with a view to their exploitation.
Four men and a woman have been charged over allegations of human trafficking involving a woman almost tricked into an abortion after a sham marriage.