25 November 2016 Last updated at 07:57 GMT
It was given to the London museum in 1905 by a rich business man and the giant skeleton has been amazing visitors for many years as they enter the museum's main hall.
It isn't a real dinosaur but a life size plaster replica of the skeleton of a Diplodocus.
Now Dippy is on the move on a trip around the UK, watch this video to find out more.
Dippy the Diplodocus is one of the Natural History Museum's most recognisable residents.