; (2) to determine whether humans can live for extended periods in space with decreasing reliance on Earth, starting with utilization of low-Earth orbit infrastructure, to— (A) identify potential roles that space resources such as energy and materials can play; (B) meet national and global needs and challenges such as potential cataclysmic threats; and (C) explore the viability of and lay the foundation for sustainable economic activities in space; (3) to maximize the role that human exploration of space can play in— (A) advancing overall knowledge of the universe; (B) supporting United States national and economic security and the United States global competitive posture; and (C) inspiring young people in their educational pursuits; (4) to build on the cooperative and mutually beneficial framework established by the International Space Station partnership agreements and experience in developing and undertaking programs and meeting objectives designed to realize the goal of human space flight set forth in subsection (a)