II Calendar No. 5 118th CONGRESS 1st Session S. 81 IN THE SENATE OF THE UNITED STATES January 25, 2023 Mr. Marshall (for himself, Mr. Paul , Ms. Ernst , Mr. Tuberville , Mrs. Blackburn , Mr. Braun , Mr. Lankford , Mr. Rubio , Mr. Cotton , and Mr. Wicker ) introduced the following bill; which was read the first time January 26, 2023 Read the second time and placed on the calendar A BILL To provide a moratorium on all Federal research grants provided to any institution of higher education or other research institute that is conducting gain-of-function research.

1. Short title This Act may be cited as the Viral Gain-of-Function Research Moratorium Act . 2. Prohibition on Federal research grants for institutions and research institutes conducting gain-of-function research (a) Definition of gain-of-Function research In this section, the term gain-of-function research means any research that— (1) could confer attributes to influenza, MERS, or SARS viruses such that the virus would have enhanced pathogenicity or transmissibility in any organism; or (2) involves methods that could enhance potential pandemic pathogens or related risky research with potentially dangerous pathogens. (b) Prohibition Notwithstanding any other provision of law, no research grants supported by Federal funds may be awarded to institutions of higher education, or other research institutes, that are conducting gain-of-function research.

January 26, 2023 Read the second time and placed on the calendar