; and (B) does not include— (i) base chemical subunits, such as individual nucleotides or nucleosides, or oligonucleotides shorter than the screening threshold typically used as polymerase chain reaction primers, as determined by the Secretary; (ii) by-products generated during sequencing that are not useful for assembly or cloning, as determined by the Secretary; or (iii) products generated from cloning or assembling of existing gene or gene fragment material, in circumstances in which the gene synthesis provider has no access or notice to the sequence design, as determined by the Secretary. (3) The term gene synthesis provider means an entity that synthesizes and distributes gene synthesis products, including bacteria, viruses, or fungi containing recombinant or synthetic nucleic acid molecules, for delivery to a customer. (4) The term manufacturers of gene synthesis equipment means an entity that produces and sells equipment for synthesizing gene synthesis products. 406. Limitation related to countries of concern conducting certain research Section 2315(c) of the PREVENT Pandemics Act ( Public Law 117–328 ) is amended— (1) in paragraph (1)— (A) by inserting that may reasonably be anticipated to involve the creation, transfer, and use of enhanced pathogens of pandemic potential or biological agents or toxins listed pursuant to section 351A(a)(1) if such research is after not fund research ; and (B) by striking , involving pathogens of pandemic potential and all that follows through the period at the end and inserting a period; (2) in paragraph (2)— (A) in the heading, by striking Conditions for listing or suspending prohibition and inserting Limitations ; and (B) in the matter preceding subparagraph (A)— (i) by striking The Secretary and inserting Beginning 5 years after an initial determination of a country of concern, the Director of National Intelligence or the Secretary ; and (ii) by inserting with respect to such country of concern after paragraph (1)