; or (B) as the Secretary determines necessary to carry out or improve preparedness and response capability at the State and local levels. (5) Reasonable time for manufacture The Secretary shall allow each manufacturer with whom the Secretary has entered into an agreement under this section a reasonable amount of time after entering into the agreement to manufacture the covered pediatric cancer drugs that will be held in reserve supply pursuant to the agreement. (c) Payment terms (1) Payment amounts (A) In general The amount paid to each manufacturer pursuant to an agreement with the Secretary under this section shall be based on— (i) the quantity of each covered pediatric cancer drug the manufacturer agrees to hold in reserve supply