classified by the European Union in Annex VI to Regulation (EC) No. 1272/2008 as respiratory sensitizer category 1. (19) Chemicals that are identified as persistent, bioaccumulative, and inherently toxic to the environment by the Canadian Environmental Protection Act Environmental Registry Domestic Substances List pursuant to subsection 66(1) of the Canadian Environmental Protection Act, 1999. (20) Group 1, 2A, or 2B carcinogens identified by the International Agency for Research on Cancer of the World Health Organization. (21) Chemicals that are identified on Part A of the list of Chemicals for Priority Action prepared by the Oslo and Paris Conventions for the Protection of the Marine Environment of the North-East Atlantic. (22) Chemicals that are skin sensitizers and irritants classified by Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. (c) Fragrance allergens A fragrance allergen specified in this subsection is an allergen that is— (1) included in Annex III of European Union Cosmetics Regulation No. 1223/2009, as required to be disclosed pursuant to European Union Detergents Regulation No. 21648/2004 (including any subsequent updates to those regulations)