; (C) the use or attempted use of such a medication or substance on a covered horse; (D) possession or attempted possession of such a medication or substance; (E) trafficking or attempted trafficking in any such medication or substance; and (F) manufacturing, producing, or formulating such a medication or substance. (2) Certain therapeutic medications and substances in quantitative amounts that exceed the irrelevant concentration present in a covered horse during a prohibited timeframe before or after the covered horse races in a covered horserace, including— (A) the administration to a covered horse of such a medication or substance; (B) the presence of such a medication or substance in a blood, urine, or hair sample of a covered horse; and (C) the use or attempted use of such a medication or substance on a covered horse; (3) Refusal or failure— (A) without compelling justification, to submit a covered horse for collection of a blood, urine, or hair sample; (B) to cooperate with the RHSO, a State racing commission, or an agent thereof during any investigation; (C) to respond truthfully, to the best of a covered person’s knowledge, to a question of the RHSO, a State racing commission, or an agent thereof with respect to any matter under the jurisdiction of such entity; and (D) in the case of a racetrack, to be in compliance with track safety standards. (4) Tampering or attempted tampering with the application of the rules issued by or process adopted by the RHSO under section 101(c), including— (A) the intentional interference, or an attempt to interfere, with the RHSO, a State racing commission, or an agent thereof; (B) the procurement or the provision of fraudulent information to the RHSO, a State racing commission, or an agent thereof