State government agencies, and were overseen by the Food and Drug Administration’s Center for Veterinary Medicine. (6) Creating a more streamlined Federal regulatory process for new pet food ingredients allows for expedited advances for nutrition, greater innovation, and more functionality in a more predictable regulatory environment. (7) Replacing the patchwork of regulation of pet food with a uniform Federal regulatory framework improves marketplace certainty, allows for more consistent and predictable ingredient review and market introductions, and enhances companion animal nutrition. (8) The nationwide availability of nutritious, safe, and affordable pet food is substantially improved through a unified comprehensive Federal system of oversight of the manufacture and sale of pet food. (9) The manufacture of pet food and its marketing and sale is undertaken throughout the United States and its territories and is interstate commerce. 3. Pet food regulation Chapter IV of the Federal Food, Drug, and Cosmetic Act ( 21 U.S.C. 341 et seq. ) is amended by adding at the end the following: 425. Pet food (a) Definitions In this section: (1) The term companion animal means a domesticated canine or feline. (2) The terms generally recognized as safe and GRAS mean generally recognized as safe under section 201(s). (3) The term pet food means any food manufactured and distributed for consumption by companion animals, including treats, nutritional supplements, and pet food ingredients. (4) The term pet food ingredient means an ingredient intended for use in pet food. (5) The term pet food ingredient submission means a submission to the Food and Drug Administration for a pet food ingredient that is a petition under section 409 for any food additive, a petition under section 721 for a color additive, or a GRAS ingredient notification under subpart E of part 570 of subchapter E of chapter I of title 21, Code of Federal Regulations (or successor regulations). (b) Preemption No State or a political subdivision of a State may