; and (2) on an annual basis, convene the Scientific Integrity Officer of each covered agency appointed under subsection (d) to discuss best practices for implementing the requirements of this section. (h) Periodic review and approval (1) Internal review The head of each covered agency shall periodically conduct a review of the scientific integrity policy and change such policy as appropriate. (2) Review by the Office of Science and Technology Policy (A) Review of substantial updates The head of each covered agency shall submit to the Office of Science and Technology Policy for approval any substantial changes to the scientific integrity policy. (B) Quinquennial review Not later than 5 years after the date of the enactment of the Scientific Integrity Act, and quinquennially thereafter, the head of each covered agency shall submit the scientific integrity policy to the Office of Science and Technology Policy for review and approval. (i) Comptroller General review Not later than 2 years after the date of the enactment of the Scientific Integrity Act, the Comptroller General of the United States shall conduct a review of the implementation of the scientific integrity policy by each covered agency. (j) Definitions In this section: (1) Agency The term agency has the meaning given the term in section 551 of title 5, United States Code. (2) Covered agency The term covered agency means an agency that funds, conducts, or oversees scientific research. (3) Covered individual The term covered individual means a Federal employee or contractor who— (A) is engaged in, supervises, or manages scientific activities; (B) analyzes or publicly communicates information resulting from scientific activities; or (C) uses scientific information or analyses in making bureau, office, or agency policy, management, or regulatory decisions. (4) Relevant committees of Congress The term relevant Committees of Congress means— (A) the Committee on Commerce, Science, and Transportation of the Senate