; or (ii) a distributor of gene synthesis product in the United States, including an entity that manufactures gene synthesis product for use by another party, whether such other party is inside and outside of the entity; and (B) does not include— (i) an entity making gene synthesis products for the entity’s own use, in circumstances in which the sequence has been previously screened in compliance with this section; (ii) an entity that manufactures gene synthesis products in the process of developing or manufacturing another product for a customer, unless the gene synthesis product is provided to the end user thereof; or (iii) any class of entity that the Secretary chooses to exempt, after consideration of the costs and benefits of exempting that class of entity from regulation under this section as a gene synthesis provider. ; (C) by inserting after paragraph (6), as so redesignated, the following: (7) The term manufacturer of gene synthesis equipment means an entity that produces for sale gene synthesis equipment. ; and (D) by adding at the end the following: (13) The term screening threshold means the minimal length of de novo gene synthesis product which ensures that the results of such screening contain enough information to allow an unambiguous analysis of such product’s potential misuse. ; and (5) in subsection (m), by striking for each of the fiscal years 2023 through 2027 and inserting for fiscal year 2023 and each subsequent fiscal year .