1. Short title This Act may be cited as the Sepsis Harm and Cost Reduction Act or the LuLu’s Law . 2. Findings Congress finds the following: (1) Sepsis affects 1.7 million people in the United States each year, and results in 350,000 adult deaths annually. (2) Sepsis is a leading cause of maternal mortality in the United States. (3) Sepsis is a leading cause of rising newborn mortality in the United States. (4) Nearly 7,000 children die from sepsis annually in the United States. (5) Many survivors face life-long after-effects of sepsis, including 14,000 annually who receive amputations. (6) Each hour a septic patient goes untreated increases the risk of death by as much as 8 percent. (7) Sepsis is the leading cause of death in United States hospitals, and the leading cause of hospital readmissions. (8) Sepsis hospitalizations cost Medicare $41.8 billion in 2019. (9) Sepsis is responsible for $62 billion in hospitalization costs annually. (10) Additional information about sepsis could help improve timely diagnosis and treatment, reducing loss of life, harm and costs due to sepsis. 3. Reducing the burden of sepsis Part P of title III of the Public Health Service Act ( 42 U.S.C. 280g et seq. ) is amended by adding at the end the following: 399V–8. Reducing the burden of sepsis (a) Definition of sepsis Not later than 120 days after the date of the enactment of the Sepsis Harm and Cost Reduction Act , the Secretary shall issue a rule specifying a definition of sepsis. Such definition may specify that sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Such definition shall be standardized across departments, agencies, and other entities within the Department of Health of Human Services. (b) State-based sepsis repository pilot programs (1) In general Subject to the availability of appropriations for a fiscal year, the Secretary shall award grants to not more than 5 States each fiscal year to establish pilot statewide sepsis repositories. (2) Application A State seeking a