; and (II) is commensurate with the economic benefits of the particular drug; and (ii) a list and explanation of the factors that support the estimated price, price range, or proposed value-based payment arrangement (2) The term value-based payment arrangement — (A) means a form of payment for a drug, other than a fixed payment per dose or other standard administration of the drug, that takes into consideration the effectiveness of the drug; and (B) may include an overall payment for a course of treatment with the drug, an overall payment to cover all indicated uses of the drug for a particular population, or another approach to payment, any of which may include a provision to vary the amount of the payment based on the effectiveness of the drug for an individual or a population, as the case may be. .