localities, Tribes, and other applicable entities related to addressing the unique needs and considerations of at-risk individuals, as defined in section 2802(b)(4) of the Public Health Service Act ( 42 U.S.C. 300hh–1(b)(4) ), in the event of a public health emergency declared by the Secretary pursuant to section 319 of the Public Health Service Act ( 42 U.S.C. 247d ). (2) Responsibilities of the centers The centers established under paragraph (1) shall conduct activities for the purpose of— (A) developing, identifying, evaluating, and disseminating evidence-based or evidence-informed strategies to improve health and other related outcomes for at-risk individuals related to public health emergencies, including by addressing such unique needs and considerations in carrying out public health and medical activities to prepare for, respond to, and recover from, such public health emergencies