; or (B) adverse effects on developing organisms that result from exposure prior to conception, during the prenatal period, or until the time of sexual maturity. (5) Vulnerable human population The term vulnerable human population means a human population that is subject to the potential for disproportionate exposure to, or the potential for disproportionate adverse effects from exposure to, a chemical substance or mixture, including— (A) infants, children, and adolescents; (B) pregnant, postpartum, or breastfeeding women; (C) older adults; (D) individuals with preexisting medical conditions; (E) workers who may be exposed to chemical substances and mixtures; (F) residents in communities subject to disproportionate exposures or adverse effects; and (G) members of any other appropriate population identified by the Secretary. (b) Establishment Not later than 1 year after the date of enactment of this section, the Secretary shall establish within the Food and Drug Administration an office, to be known as the Office of Food Chemical Safety, Dietary Supplements, and Innovation (referred to in this section as the Office ), to evaluate and reassess the safety, within the meaning of section 409, of substances and classes of substances, including food additives, food contact substances, substances generally recognized as safe for use in food, color additives, and prior-sanctioned substances. (c) Safety reassessments Not later than 3 years after the date on which the Office is established, and not less frequently than once every 3 years thereafter, the Office shall— (1) reassess the safety of not less than 10 of the substances or classes of substances described in subsection (b); and (2) issue final regulations— (A) determining that any such substance or class of substance is safe within the meaning of section 409 and establishing the conditions of use, if any, under which any such substance or class of substances can be used safely within the meaning of such section