political or social factors. (d) Qualified population health product manufacturing facility For purposes of this section, the term qualified population health product manufacturing facility means any qualified medical manufacturing facility (as defined in section 1400AA–1) that produces a population health product (as defined in section 319L(a)(11) of the Public Health Service Act) which the Secretary of Health and Human Services has identified for support through a strategic initiative under section 319L(c)(4)(F)(ii) of the Public Health Service Act. 1400AA–4. Designation of economically distressed zones (a) In general For purposes of this subchapter, the term economically distressed zone means any population census tract within the United States which— (1) has a poverty rate of not less than 35 percent for each of the 5 most recent calendar years for which information is available, or (2) satisfies each of the following requirements: (A) has pervasive poverty, unemployment, low labor force participation, and general distress measured as a prolonged period of economic decline measured by real gross national product, (B) has a poverty rate of not less than 30 percent for each of the 5 most recent calendar years for which information is available, and (C) has been designated as such by the Secretary and the Secretary of Commerce pursuant to an application under subsection (b). (b) Application for designation (1) In general An application for designation as an economically distressed zone may be filed by a State or local government in which the population census tract to which the application applies is located. (2) Requirements Such application shall include a strategic plan for accomplishing the purposes of this subchapter, which— (A) describes the coordinated economic, human, community, and physical development plan and related activities proposed for the nominated area, (B) describes the process by which the affected community is a full partner in the process of developing and implementing the plan and the