; (II) the concentration of current supply of the essential generic medicine or active pharmaceutical ingredients of the essential generic medicine in one geographical region; (III) whether there are less than 2 manufacturers of the essential generic medicine or active pharmaceutical ingredients of the essential generic medicine; and (IV) the potential for increased demand in a public health emergency. (E) Director of the strategic active pharmaceutical ingredients reserve The Secretary shall appoint a Director of the Strategic Active Pharmaceutical Ingredients Reserve who has experience in one or more of the following areas: supply chain management, disaster response, pharmaceutical or active pharmaceutical ingredient development, or logistics. Such Director shall ensure a sufficient supply of the active pharmaceutical ingredients and critical components necessary to manufacture the essential generic medicines included on the list under subsection (a) in an amount adequate to serve the needs of patients living in the United States and in the appropriate dosage forms. (c) Appeal process The Secretary shall establish a process by which stakeholders may appeal a determination by the Secretary not to include an essential generic medicine on the list under subsection (a). (d) Definitions In this section: (1) Drug The term drug has the meaning given such term in section 201(g) of the Federal Food, Drug, and Cosmetic Act, and includes a biological product (as defined in section 351(i) of this Act). Such term includes prescription and nonprescription drugs, or active pharmaceutical ingredients of drugs. (2) Essential generic medicine The term essential generic medicine means a drug for which a generic is approved, that is medically necessary to have available at all times because the drug is— (A) commonly used to prevent, mitigate, or treat a common disease or condition, or used in a common procedure; (B) an antibiotic or antifungal used to treat an infectious diseases