; Whereas, in 2020, the National Academies of Science, Engineering, and Medicine (NASEM) developed a comprehensive Strategic Plan and Blueprint for Action to Address Sickle Cell Disease, which cited the need for new innovative therapies as well as to address barriers that may impact delivery and access to approved treatments; Whereas, in 2020, the Department of Health and Human Services, in partnership with the American Society of Hematology and SickleInAfrica, in collaboration with the World Health Organization, hosted a webinar for a joint effort to strengthen SCD efforts during the coronavirus disease (COVID–19) pandemic and beyond; Whereas American Society of Hematology member and recently deceased Kwaku Ohene-Frempong, M.D., Professor Emeritus of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania, who served on the Global Coalition on SCD, has been a leader in advancing the body of knowledge in SCD research, public health, and medicine, and is recognized as immeasurably benefitting thousands of children worldwide; Whereas there are emerging genetic therapy technologies, including gene editing, that can modify a patient’s own hematopoietic stem cells with the goal of the patient being able to generate healthy red blood cells to prevent sickle cell crises; Whereas while hematopoietic stem cell transplantation (commonly known as HSCT ) is currently the only cure for SCD, and while advances in treating the associated complications of SCD have occurred, more research is needed to find widely available treatments and cures to help individuals with SCD