; (ii) have a prominent design that visually contrasts with existing packaging design; and (iii) be sufficiently large to be easily legible. (3) In promulgating regulations regarding the interpretive nutrition information required under subparagraph (1) and the standardized symbol system required under subparagraph (2)(A), the Secretary shall take into account published reports by the Health and Medicine Division of the National Academy of Sciences, Engineering, and Medicine regarding such information, and base regulations on the following principles: (A) Consumers should be able to quickly and easily comprehend the meaning of the system as an indicator of a product’s contribution to a healthy diet without requiring specific or sophisticated nutritional knowledge. (B) The information should be provided to facilitate consumer selection of healthy product options, including among nutritionally at-risk subpopulations. (C) The Secretary should periodically evaluate the standardized symbol system to assess its effectiveness in providing information to facilitate consumer selection of healthy product options and the extent to which manufacturers are offering healthier products as a result of the disclosure. (D) The implementation of the information disclosure should be accompanied by appropriate consumer education and promotion campaigns determined by the Secretary. . (b) Report (1) In general Not later than 5 years after the effective date specified in final regulations issued by the Secretary pursuant to section 4(b), the Secretary of Health and Human Services (referred to in this Act as the Secretary ) shall submit to Congress a report that— (A) evaluates whether implementation of the amendment made by subsection (a) has been associated with an increase in the prevalence of products containing low- or no-calorie sweeteners in the United States food supply