; and (B) approve or deny all applications received during the period described in that subsection not later than 45 days after the end of that period. (2) Denial The Secretary shall deny an application received under subsection (c)(1) if— (A) the Secretary has already selected 75 responsible parties for enrollment in the pilot program; or (B) the Secretary determines that the responsible party submitting the application does not meet each criterion specified in subsection (a)(5). (3) Appeal (A) In general A responsible party seeking to enroll in the pilot program whose application has been denied under paragraph (2) may submit to the Secretary a written appeal within— (i) the 10-day period beginning on the date on which the responsible party receives written notification of the denial; or (ii) a longer period, if the responsible party makes a request for additional time to submit such appeal and the Secretary grants such request. (B) Decision The Secretary shall, within a reasonably prompt period, grant or deny an appeal under subparagraph (A) in writing, which shall include the reasons for the decision. (e) Requirements A responsible party shall, as a condition of enrollment in the pilot program, agree to— (1) maintain, move, and dispose of covered microorganisms in a manner that prevents unauthorized release, spread, dispersal, or persistence of those covered microorganisms in the environment; (2) unless otherwise authorized under a permit under this Act, only move a covered microorganism between sites that are responsible party biocontainment facilities; (3) maintain, move, and dispose of each covered microorganism separately from other organisms; (4) ensure that each covered microorganism is maintained, moved, and disposed of in a manner commensurate with the plant pest risk posed by that covered microorganism