as necessary to implement the requirements of this section. (4) Effective date Any prohibition included in the guidance established by the Federal entity in accordance with paragraph (1) shall take effect not later than one year after the establishment of such guidance. (c) Rule of construction Nothing in this section shall be construed— (1) to require any covered biotechnology equipment or service in use or resident in equipment, systems, or services as of the day before the applicable effective date specified in subsection (b)(4) to be removed or replaced