1. Short title This Act may be cited as the Rare disease Advancement, surveillance Research, and Education Act of 2019 or the RARE Act of 2019 . 2. NIH rare disease regional centers of excellence Paragraph (1) of section 402A(a) of the Public Health Service Act ( 42 U.S.C. 282a(a) ) is amended by adding at the end the following: In addition to the amounts authorized to be appropriated by the preceding sentence, there are authorized to be appropriated such sums as may be necessary for each of fiscal years 2020 through 2024 for carrying out section 481A (relating to rare disease regional centers of excellence). . 3. CDC Surveillance of Rare Diseases and Conditions Title III of the Public Health Service Act is amended by inserting after section 317T of such Act ( 42 U.S.C. 247b–22 ) the following: 317U. CDC surveillance of rare diseases and conditions (a) In general The Secretary may, as appropriate— (1) enhance and expand infrastructure and activities to track the epidemiology of up to 4 rare diseases and conditions selected under subsection (c)(1); and (2) incorporate information obtained through such activities into an integrated surveillance system to be known as the National Rare Disease or Condition Surveillance System. (b) Research The Secretary shall ensure that the National Rare Disease or Condition Surveillance System is designed in a manner that provides information that facilitates further research on rare diseases and conditions. (c) Content In carrying out subsection (a), the Secretary— (1) shall select up to 4 rare diseases and conditions that are determined by the Secretary to have— (A) a high rate of mortality or morbidity; or (B) potential for meaningful research and treatment; (2) shall provide for the collection and storage of information on the incidence and prevalence of such rare diseases and conditions in the United States