; and (10) to include the active leadership and participation of women and girls in humanitarian program design, implementation, and evaluation. 4. Safe from the Start authority (a) Safe from the Start programming The Secretary of State, in consultation with the Assistant Secretary of the Bureau of Population, Refugees, and Migration and in coordination with the Administrator of the United States Agency for International Development (in consultation with the Director of the Office of Foreign Disaster Assistance), shall direct and oversee all United States foreign assistance that addresses humanitarian crises in a manner that implements a Safe from the Start programming focus on the following objectives: (1) Preventing and reducing the incidence of gender-based violence. (2) Ensuring quality protection for survivors of such crises beginning with the onset of the emergency through timely and effective action. (3) Promoting standards and activities to prevent, mitigate, and respond to gender-based violence. (4) Advance the empowerment of survivors and individuals at risk of gender-based violence. (b) Standards and guidelines The Secretary shall develop guidelines, toolkits, reporting mechanisms, and other institutional response and accountability measures through the Safe from the Start programming described in subsection (a) in order to incorporate effective gender-based violence prevention and response activities across all humanitarian assistance programs and projects, including through— (1) the promotion of minimum standards, indicators, and metrics to assess the adequacy of interventions relating to gender-based violence, taking into consideration the Guidelines for Integrating Gender-Based Violence Interventions in Humanitarian Action published by the United Nations Inter-Agency Standing Council in 2015, the assessment released by the Real-Time Accountability Partnership on Gender-Based Violence in Emergencies in 2016, and the Minimum Standards for Child Protection in Humanitarian Action published by the