; and (II) subparagraph (A) of paragraph (1), if the applicable State requires practitioners conducting research to register with a board or authority described in such subparagraph (A). (iii) (I) Not later than 60 days after the date on which the Attorney General receives a complete application for registration under this subparagraph, the Attorney General shall— (aa) approve the application; or (bb) request supplemental information. (II) For purposes of subclause (I), an application shall be deemed complete when the applicant has submitted documentation showing that the requirements under clause (i) are satisfied. (iv) Not later than 30 days after the date on which the Attorney General receives supplemental information as described in clause (iii)(I)(bb) in connection with an application described in this subparagraph, the Attorney General shall approve or deny the application. (v) If an application described in this subparagraph is denied, the Attorney General shall provide a written explanation of the basis of denial to the applicant. . 102. Research protocols (a) In general Paragraph (2)(B) of section 303 of the Controlled Substances Act ( 21 U.S.C. 823(f) ), as amended by section 101 of this Act, is further amended by adding at the end the following: (vi) (I) If the Attorney General grants an application for registration under clause (i), the registrant may amend or supplement the research protocol without reapplying if the registrant does not change— (aa) the quantity or type of drug; (bb) the source of the drug