; (B) the recommended format in which to submit to the Secretary such data and information, including any applicable foreign data and information, related to a cosmetic ingredient or nonfunctional constituent (or category thereof) that has been selected for such review; (C) the manner and the number of days by which the Secretary intends to review and respond to such data and information, including with respect to providing a scientific rationale for any additional data and information; (D) the process for communication between the Secretary and industry related to an ingredient or nonfunctional constituent (or a category thereof) that has been selected for review; and (E) includes such other information as the Secretary determines appropriate. (3) Timing Not later than 24 months after the date of the enactment of this Act, the Secretary shall issue draft guidance under paragraph (1) on the implementation of section 608 of the Federal Food, Drug, and Cosmetic Act (as added by subsection (a)). The Secretary shall issue final guidance on the implementation of such section not later than 6 months after the date on which the comment period for the draft guidance closes. (d) GAO study Not later than 6 years after the date of the enactment of this Act, the Comptroller General of the United States shall submit to the Committee on Energy and Commerce of the House of Representatives and the Committee on Health, Education, Labor, and Pensions of the Senate a report addressing the effectiveness and overall impact of the ingredient review program established under section 608 of the Federal Food, Drug, and Cosmetic Act (as added by subsection (a)), including with respect to its impact on the safety of cosmetic ingredients— (1) for each ingredient or nonfunctional constituent (or category thereof) selected for review— (A) whether the ingredient or nonfunctional constituent (or category thereof) was determined— (i) to be safe in cosmetic products without the need for specified conditions of use or tolerances