; and (E) the ability to support Federal agencies with technical assistance for advanced pharmaceutical technologies, with an emphasis on creating a secure national pharmaceutical stockpile and the ability to rapidly address drug shortages; and (3) submit an application to the Secretary at such time, in such form, and in such manner as the Secretary may require. (c) Termination The Secretary may terminate the designation of an entity designated under subsection (a) upon a determination that the entity no longer meets the requirements of subsection (b). (d) Annual report Not later than 1 year after the date on which the first designation is made under subsection (a), and annually thereafter, the Secretary shall submit a report to Congress on the activities of the entities designated under such subsection. (e) Authorization of appropriations To carry out this section, there are authorized to be appropriated $100,000,000 for the period of fiscal year 2021 through 2025. .