or (2). (4) Guidelines for hemodynamic support with explicit physiologic and treatment goals, a methodology for invasive and non-invasive hemodynamic monitoring, and timeframe goals. (5) With respect to children (including infants), guidelines for fluid resuscitation consistent with any evidence-based guidelines for severe sepsis and septic shock that have defined therapeutic goals for children. (6) A process for identifying the infectious source of the sepsis, severe sepsis, or septic shock and delivering early broad spectrum antibiotics with timely reevaluation to adjust treatment in a manner that targets any identified infectious source. (7) Criteria for use, based on accepted evidence of vasoactive agents. .