than $3,000,000,000 in 2018, $610,000. (E) Tier III–A For a registrant that has gross annual sales of at least $1,000,000,000 per annum but less than $2,000,000,000 in 2018, $500,000. (F) Tier III–B For a registrant that has gross annual sales of at least $500,000,000 per annum but less than $1,000,000,000 in 2018, $395,000. (G) Tier IV–A For a registrant that has gross annual sales of at least $200,000,000 per annum but less than $500,000,000 in 2018, $325,000. (H) Tier IV–B For a registrant that has gross annual sales of at least $100,000,000 per annum but less than $200,000,000 in 2018, $275,000. (I) Tier V–A For a registrant that has gross annual sales of at least $80,000,000 per annum but less than $100,000,000 in 2018, $185,000. (J) Tier V–B For a registrant that has gross annual sales of at least $60,000,000 per annum but less than $80,000,000 in 2018, $95,000. (K) Tier VI–A For a registrant that has gross annual sales of at least $40,000,000 per annum but less than $60,000,000 in 2018, $15,000. (L) Tier IV–B For a registrant that has gross annual sales of at least $20,000,000 per annum but less than $40,000,000 in 2018, $12,000. (M) Tier VII–A For a registrant that has gross annual sales of at least $10,000,000 per annum but less than $20,000,000 in 2018, $500. (d) Adjustments (1) Inflation adjustment (A) In general For fiscal year 2021 and each subsequent fiscal year, the revenues and fee amounts under subsection (c)(3) shall be adjusted by the Food and Drug Administration in the annual Federal Register notice establishing fees in subsection (c)(1), by an amount equal to the sum of— (i) one