; (2) is in effect on the date of enactment of this Act; and (3) was approved for any State that ranks in the top quintile of all States in terms of the highest mean drug overdose death rate per 100,000 residents for the most recent 3-year period preceding the date of enactment of this Act for which data is available. 11. Separate ambulatory payment classifications (APC) codes under the Medicare hospital outpatient department prospective payment system and the Medicare ambulatory surgical center payment system for surgeries utilizing non-opioid pain management drugs (a) Hospital outpatient department prospective payment system Section 1833(t) of the Social Security Act ( 42 U.S.C. 1395l(t) ) is amended— (1) in paragraph (2)(A), by striking the Secretary and inserting subject to paragraph (23), the Secretary ; and (2) by adding at the end the following new paragraph: (23) Separate APCs for surgeries using non-opioid pain management drugs (A) In general In the case of covered OPD services furnished on or after January 1, 2021, the classification system developed under paragraph (2)(A) shall provide for separate ambulatory payment classification codes for— (i) surgeries that utilize non-opioid drugs, including such drugs delivered using an external infusion pump and the delivery mechanisms necessary for the delivery of such drugs, to treat pain after the surgery; and (ii) surgeries that utilize opioid drugs to treat pain after the surgery. (B) Application For purposes of this paragraph, the Secretary shall— (i) treat any drug with a Food and Drug Administration indication for pain management during and after surgery that is also non-opioid as a non-opioid drug