; and (B) the Committee on Science, Space, and Technology of the House of Representatives. (4) Cislunar space The term cislunar space means the region of space beyond low-Earth orbit out to and including the region around the surface of the Moon. (5) Deep space The term deep space means the region of space beyond low-Earth orbit, including cislunar space. (6) Development cost The term development cost has the meaning given the term in section 30104 of title 51, United States Code. (7) ISS The term ISS means the International Space Station. (8) ISS management entity The term ISS management entity means the organization with which the Administrator has entered into a cooperative agreement under section 504(a) of the National Aeronautics and Space Administration Authorization Act of 2010 ( 42 U.S.C. 18354(a) ). (9) NASA The term NASA means the National Aeronautics and Space Administration. (10) Johnson Space Center The term Johnson Space Center means the Lyndon B. Johnson Space Center in Houston, Texas. (11) Orion The term Orion means the multipurpose crew vehicle described in section 303 of the National Aeronautics and Space Administration Authorization Act of 2010 ( 42 U.S.C. 18323 ). (12) OSTP The term OSTP means the Office of Science and Technology Policy. (13) Space Launch System The term Space Launch System means the Space Launch System authorized under section 302 of the National Aeronautics and Space Administration Act of 2010 ( 42 U.S.C. 18322 ). (14) Lunar Gateway The term Lunar Gateway means the Lunar Orbital Platform referenced in the Consolidated Appropriations Act, 2019 ( Public Law 116–6 ). I Human spaceflight and exploration 101. Steppingstone approach to exploration (a) In general Section 70504 of title 51, United States Code, is amended to read as follows: 70504. Steppingstone approach to exploration (a) In general The Administrator, in sustainable steps, may conduct missions to intermediate destinations, such as the Moon, in accordance with section 20302(b), and on a timetable determined by the