; and (III) for most individuals without signs or symptoms of a particular disease or condition there is at least moderate certainty that the net benefit is small. (iv) Grade D The Task Force shall assign a product or service Grade D if the Task Force concludes that the current evidence is sufficient to assess the balance of benefits and risks of the product or service, and, on the basis of such evidence, recommends against the product or service and determines that there is moderate or high certainty that the product or service has no net benefit or that the harm of the product or service outweighs the benefits. (v) Grade I The Task Force shall assign a product or service Grade I if the Task Force concludes that the current evidence is not sufficient to assess the balance of benefits and risks of the product or service. (E) Changes in grading system (i) In general The Director may provide, by regulation, for changes in the grading system described in subparagraph (D). (ii) Impact of changes If the Director makes a change in the grading system under clause (i) for a particular grade, the Task Force shall review and re-grade the products or services previously classified within that grade. Any such review and regrading may be done through an expedited process so long as any change in grade does not take effect before the review of that change in grade is completed. (5) Role of agency The Agency shall provide ongoing administrative, research, and technical support for the operations of the Task Force, including coordinating and supporting the dissemination of its recommendation statements, ensuring adequate staff resources, and assistance to those organizations requesting it for implementation of the recommendations of the Task Force. (6) Preventive services advisory board (A) In general The Task Force shall convene a preventive services advisory board (in this subsection referred to as the board ) composed of representatives of appropriate public and private entities with an interest in clinical preventive