; and (2) the safety of the vessel and those on board will not be adversely affected. 4516. Regulations; considerations and limitations In prescribing a regulation under this chapter, the Secretary— (1) shall consider the specialized nature and economics of the operations and the character, design, and construction of the vessel; and (2) may not require the alteration of a vessel or associated equipment that was constructed or manufactured before the effective date of such regulation. 4517. Fishing safety grants (a) Safety training grants (1) Establishment The Secretary of Health and Human Services shall establish a Fishing Safety Training Grant Program to provide funding to municipalities, port authorities, other appropriate public entities, not-for-profit organizations, and other qualified persons that provide commercial fishing safety training. (2) Use of funds Entities receiving funds under this section may use such funds— (A) to conduct fishing vessel safety training for vessel operators and crewmembers that— (i) in the case of vessel operators, meets the requirements of section 4506; and (ii) in the case of crewmembers, meets the requirements of sections 4506(b)(1), 4506(b)(4), 4506(c), and 4506(d), and such requirements of section 4506(b)(2) as are appropriate for crewmembers