; Whereas the GAVI Alliance is participating in efforts to test and implement an effective vaccine to prevent malaria, a disease that kills more than 500,000 children a year; Whereas the GAVI Alliance supports the strengthening of health systems to ensure effective immunization and health services; Whereas even with significant progress in increasing immunization coverage through the GAVI Alliance support, 19,400,000 children annually in lower income countries still miss out on a full course of the most basic vaccines; Whereas the cumulative effects of population growth, displacement, and increasing fragility, coupled with those of recurrent disease outbreaks, are threatening hard-won gains and increase the risk of backsliding; Whereas outbreaks risk jeopardizing the achievements of national routine immunization programs, and given the enormous increase in human mobility, threaten global health security; Whereas vaccines are widely regarded as a high-impact, evidence-based intervention and are known as one of the best buys in global health and recognized as one of the most efficient, cost-effective, and successful health initiatives in history; Whereas the prevention of infectious disease through immunization in GAVI-eligible countries provides protection and health security in the United States; Whereas United States investment in the GAVI Alliance complements and enhances the effectiveness of other United States investments in global health, particularly in child survival; Whereas the GAVI Alliance is committed to working with partners, including United States bilateral programs run by the United States Agency for International Development and the Centers for Disease Control and Prevention to ensure children in developing nations have access to vaccines and immunizations; Whereas access to vaccines is an essential part of ending preventable childhood deaths and preventing other fatal diseases