; and (B) shall be filled in the same manner as the original appointment. (f) Meetings (1) In general The Commission shall meet at the call of the Chairperson. (2) Initial meeting Not later than 180 days after the date of the enactment of this Act, the Commission shall hold its initial meeting. (3) Principal group The principal group shall meet not less frequently than twice each year. (4) Staff group The staff group described in subsection (d)(1)(C) shall meet as determined by the Chairperson based on the activities of the Commission. (g) Bylaws (1) In general Not later than 180 days after the date of the enactment of this Act, the Commission shall develop bylaws for the operation of the Commission. (2) Elements The bylaws developed under paragraph (1) shall include— (A) information on the membership of the Commission; (B) the number of annual meetings required for the principal group and the staff group; (C) the decision-making process of the Commission; (D) the process by which disputes are resolved; and (E) such other information and policies as the Commission considers appropriate. (h) Primary responsibilities The Commission shall— (1) develop an integrated, comprehensive global health strategy, in accordance with section 5 and in cooperation with global health implementing agencies, to ensure that global health activities and programs supported by the United States are consistent with the strategic priorities and policies of the United States; (2) recommend methods to improve alignment, coordination, planning, and implementation to ensure the greatest possible impact and overall effectiveness of United States global health efforts and programs; (3) in coordination with the Committee, advise the National Security Council on global health issues that potentially impact the domestic health status, defense operations, development programs, diplomacy efforts, and strategic interests of the United States; (4) advise the Committee on country and regional challenges