; (2) where the defendant has agreed or consented to be sued in the instant action; (3) where an inventor named on the patent in suit conducted research or development that led to the application for the patent in suit; (4) where a party has a regular and established physical facility that such party controls and operates, not primarily for the purpose of creating venue, and has— (A) engaged in management of significant research and development of an invention claimed in a patent in suit prior to the effective filing date of the patent; (B) manufactured a tangible good that is alleged to embody an invention claimed in a patent in suit; or (C) implemented a manufacturing process for a tangible good in which the process is alleged to embody an invention claimed in a patent in suit; or (5) in the case of a foreign defendant that does not meet the requirements of section 1400(b) of title 28, in accordance with section 1391(c)(3) of such title. (c) Injunction (1) Presumption Upon a finding by a court of infringement of an inventor-owned patent not proven invalid or unenforceable, the court shall presume, respectively, that— (A) further infringement of the patent would cause irreparable injury