; or (ii) in a manner substantially affecting interstate or foreign commerce; or (B) to breed or possess any prohibited wildlife species. (2) Limitation on application Paragraph (1) does not apply to— (A) an entity exhibiting animals to the public under a Class C license from the Department of Agriculture, or a Federal facility registered with the Department of Agriculture that exhibits animals, if that entity or facility— (i) holds that license or registration in good standing; (ii) does not allow any individual to come into direct physical contact with a prohibited wildlife species, unless— (I) that individual is— (aa) a trained professional employee or contractor of the entity or facility (or an accompanying employee receiving professional training); or (bb) a licensed veterinarian (or a veterinary student accompanying that veterinarian); or (II) (aa) that individual is directly supporting conservation programs of the entity or facility; and (bb) the contact is— (AA) not in the course of commercial activity (which may be evidenced by advertisement or promotion of that activity or other relevant evidence); and (BB) incidental to humane husbandry conducted pursuant to a species-specific, publicly available, peer-edited population management and care plan that has been provided to the Secretary with justifications that the plan reflects established conservation science principles, incorporates genetic and demographic analysis of a multi-institution population of animals covered by the plan, and promotes animal welfare by ensuring that the frequency of breeding is appropriate for the species; and (iii) ensures that, during public exhibition of a lion (Panthera leo), tiger (Panthera tigris), leopard (Panthera pardus), snow leopard (Uncia uncia), jaguar (Panthera onca), cougar (Puma concolor), or any hybrid of any of those animals, the animal is not less than 15 feet from members of the public unless there is a permanent barrier sufficient to prevent public contact; (B) a State college, university, or agency