; and (4) in paragraph (2), as so redesignated— (A) in the heading, by striking Contents of notice and inserting Information required to be submitted ; (B) in the matter preceding subparagraph (A), by striking paragraph (2) and inserting paragraph (1) ; (C) in subparagraph (A), by striking or intended to be identified ; (D) in subparagraph (D), by striking and at the end; (E) in subparagraph (E), by striking the period and inserting ; and ; and (F) by adding at the end the following: (F) whether the facility is a contract manufacturing organization facility. . (f) Effect of failure To pay fees Section 744B(g) of the Federal Food, Drug, and Cosmetic Act ( 21 U.S.C. 379–42(g) ) is amended— (1) in paragraph (1), by adding at the end the following: This paragraph shall cease to be effective on October 1, 2022. ; (2) in paragraph (2)(C)(ii), by striking of 505(j)(5)(A) and inserting of section 505(j)(5)(A)