; composition (1) Chair The steering committee shall be chaired by the Assistant Administrator of the Office of Research and Development of the Environmental Protection Agency. (2) Composition The steering committee shall be composed of 15 members, all of whom shall be active, full-time employees of the Environmental Protection Agency, with at least one member representing each relevant program office and each regional office of the Environmental Protection Agency. The members of the steering committee shall be appointed by the Administrator of the Environmental Protection Agency. Any vacancy shall be filled in the same manner as the initial appointment. (d) Meetings The steering committee shall meet at least once each calendar year. (e) Third-Party assessment requirements The requirements specified in this subsection with respect to a third-party assessment of a chemical substance are that the assessment— (1) is conducted using scientific standards specified in section 4; (2) has undergone independent scientific review for transparency, completeness, and quality; and (3) reflects the best available science and the weight of the available scientific evidence. 4. Scientific standards Covered assessments carried out under section 2 and discussion of such assessments and review of third-party assessments carried out under section 3, shall be conducted using scientific information, technical procedures, measures, methods, protocols, methodologies, or models in a manner consistent with the best available science. In carrying out such an assessment, the relevant program office shall integrate all lines of scientific evidence and consider, as applicable— (1) the extent to which the scientific information, technical procedures, measures, methods, protocols, methodologies, or models employed to generate the scientific information are reasonable for and consistent with the intended use of the scientific information