; (B) is located in an area where the aggregate success rate for applications for National Institutes of Health funding has been historically low; (C) is able to build on an existing infrastructure of service and public health research; (D) has experience with providing care, caregiver support, and research related to Alzheimer's disease; and (E) is integrated into existing local government and public health infrastructures. (4) Distribution of awards In awarding cooperative agreements under this subsection, the Secretary, to the extent practicable, shall ensure equitable distribution of awards based on geographic area, including consideration of rural areas, and the burden of the disease on sub-populations. (d) Cooperative agreements to public health departments (1) In general The Secretary shall award cooperative agreements to health departments of States, of political subdivisions of States, and of Indian tribes and tribal organizations to promote cognitive functioning, address cognitive impairment for individuals living in such communities, help meet the needs of caregivers, and address unique aspects of Alzheimer’s disease, as follows: (A) The Secretary shall award core capacity cooperative agreements to such health departments to support the development and implementation of systems change, communications, and programmatic interventions with respect to Alzheimer’s disease, including activities involving— (i) educating and informing the public based on established public health research and data; (ii) supporting early detection and diagnosis; (iii) reducing the risk of potentially avoidable hospitalizations; (iv) reducing the risk of cognitive decline and cognitive impairment; (v) enhancing support to meet the needs of caregivers; (vi) supporting care planning and management