impacted by the Mexico City Policy, also widely referred to as the global gag rule , which was reinstated and expanded by President Donald J. Trump on January 23, 2017. LGBTI people often receive much of their healthcare through reproductive health clinics, and organizations that cannot comply with the policy are forced to discontinue work on United States-supported global health projects that are frequently used by LGBTI populations, including HIV prevention and treatment, stigma reduction, and research. (12) Because they face tremendous discrimination in the formal labor sector, many sex workers are also LGBTI individuals, and many sex-worker-led programs and clinics serve the LGBTI community with safe, non-stigmatizing, medical and social care. USAID has also referred to sex workers as a most-at-risk population . The anti-prostitution loyalty oath that health care providers receiving United States assistance must take isolates sex-worker-led and serving groups from programs and reinforces stigma, undermining both the global AIDS response and human rights. The Supreme Court found this requirement unconstitutional as it applies to United States nongovernmental organizations and their foreign affiliates in 2013. (13) According to the Trans Murder Monitoring Project, which monitors homicides of transgender individuals, 2,343 transgender and gender-diverse people were murdered between 2008 and 2016, in 69 countries. (14) In many countries, intersex individuals experience prejudice and discrimination because their bodies do not conform to general expectations about sex and gender. Because of these expectations, medically unnecessary interventions are often performed in infancy without the consent or approval of intersex individuals, in violation of international human rights standards. (15) Asylum and refugee protection are critical last-resort protections for LGBTI individuals, but those who seek such protections face ostracization and abuse in refugee camps and detention facilities. They are frequently targeted