; or (ii) the first business day after the enactment of an appropriations Act providing for the collection and obligation of fees for such year under this section for such year. ; (6) by redesignating paragraph (5) as paragraph (6); and (7) by inserting after paragraph (4) the following: (5) Generic drug applicant program fee (A) In general A generic drug applicant program fee shall be assessed annually as described in subsection (b)(2)(E). (B) Amount The amount of fees established under subparagraph (A) shall be established under subsection (d). (C) Notice Within the timeframe specified in subsection (d)(1), the Secretary shall publish in the Federal Register the amount of the fees under subparagraph (A) for such fiscal year. (D) Fee due date For each of fiscal years 2018 through 2022, the fees under subparagraph (A) for such fiscal year shall be due on the later of— (i) the first business day on or after October 1 of each such fiscal year; or (ii) the first business day after the date of enactment of an appropriations Act providing for the collection and obligation of fees for such fiscal year under this section for such fiscal year. . (b) Fee revenue amounts Section 744B(b) of the Federal Food, Drug, and Cosmetic Act ( 21 U.S.C. 379j–42(b) ) is amended— (1) in paragraph (1)— (A) in subparagraph (A)— (i) in the heading, by striking 2013 and inserting 2018 ; (ii) by striking 2013 and inserting 2018 ; (iii) by striking $299,000,000 and inserting $493,600,000 ; and (iv) by striking Of that amount and all that follows through the end of clause (ii); and (B) in subparagraph (B)— (i) in the heading, by striking 2014 through 2017 and inserting 2019 through 2022 ; (ii) by striking 2014 through 2017 and inserting 2019 through 2022 ; (iii) by striking paragraphs (2) through (4) and inserting paragraphs (2) through (5) ; and (iv) by striking $299,000,000 and inserting $493,600,000