; (D) to standardize systems and approaches for designing continuous manufacturing; and (E) to develop a plan to establish a continuous manufacturing workforce. (d) Termination of designation The Secretary may terminate the designation of any National Center of Excellence designated under this section if the Secretary determines such National Center of Excellence no longer meets the criteria specified in subsection (c). Not later than 60 days before the effective date of such a termination, the Secretary shall provide written notice to the National Center of Excellence, including the rationale for such termination. (e) Conditions for designation As a condition of designation as a National Center of Excellence under this section, the Secretary shall require that an institution of higher education enter into an agreement with the Secretary under which the institution agrees— (1) to collaborate directly with the Food and Drug Administration to publish the reports required by subsection (g); (2) to share data with the Food and Drug Administration regarding best practices and research generated through the funding under subsection (f); (3) to provide an annual report to the Food and Drug Administration regarding the institution’s activities under this section; and (4) to develop, along with industry partners and another institution or institutions designated under this section, if any, a roadmap for developing a continuous manufacturing workforce. (f) Funding (1) In general The Secretary shall award funding to the National Centers of Excellence designated under this section for the purpose of studying and recommending improvements to continuous manufacturing, including such improvements as may enable the Centers— (A) to continue to meet the conditions specified in subsection (e); (B) to submit reports under subsection (e)(3)