; (2) given the persistent levels of poverty in the distressed counties in the Appalachian region, more grant expenditures and emphasis should be devoted to those counties; and (3) therefore, the 50 percent threshold in section 14524(d) of title 40, United States Code, should be increased to 60 percent. 3. Mission of the Appalachian Regional Commission Section 14301 of title 40, United States Code, is amended by striking subsection (a) and inserting the following: (a) Establishment and mission (1) Establishment There is an Appalachian Regional Commission (referred to in this chapter as the Commission ). (2) Mission The mission of the Commission shall be to focus primarily on poverty reduction and economic development in areas in the Appalachian region with the most persistent poverty. . 4. Headquarters of the Appalachian Regional Commission (a) In general Section 14301 of title 40, United States Code, is amended by adding at the end the following: (g) Headquarters The headquarters of the Commission shall be located in the Appalachian region. . (b) Implementation The Federal Cochairman of the Commission shall take such actions as may be necessary to carry out the amendment made by subsection (a). 5. Grant expenditures Section 14524(d) of title 40, United States Code, is amended by striking 50 percent and inserting 60 percent . 6. Area development funds for distressed counties Section 14526(b) of title 40, United States Code, is amended— (1) by striking In program and and inserting the following: (1) In general In program and