; and (II) demonstrating for each such service area, an increase equal to or greater than the national increase in such problems, between— (aa) 1999; and (bb) 2016 or the latest year for which data are available; and (ii) a description of how the eligible entity will prioritize support for significantly impacted service areas described in clause (i)(I). (B) Information To meet the requirements described in subparagraph (A)(i)(II), the eligible entity may use information including data on— (i) the incidence or prevalence of opioid abuse and other substance use disorders; (ii) the age-adjusted rate of drug overdose deaths, as determined by the Director of the Centers for Disease Control and Prevention; (iii) the rate of non-fatal hospitalizations related to opioid abuse or other substance use disorders; (iv) the number of arrests or convictions, or a relevant law enforcement statistic, that reasonably shows an increase in opioid abuse or another substance use disorder; or (v) in the case of an eligible entity described in subsection (a)(3)(C), other alternative relevant data as determined appropriate by the Secretary. (C) Support for state strategy The eligible entity may include in the application information describing how the proposed services and activities are aligned with the State, outlying area, or Tribal strategy, as applicable, for addressing problems described in subparagraph (A) in specific service areas or across the State, outlying area, or Tribal land. (3) Economic and employment conditions demonstrate additional Federal support needed (A) Demonstration An eligible entity shall include in the application information that demonstrates that a high rate of a substance use disorder has caused, or is coincident to— (i) an economic or employment downturn in the service area