; or ; and (C) by adding at the end the following: (iii) accommodate different approved risk evaluation and mitigation strategies for a reference drug product and a drug that is the subject of an abbreviated new drug application. ; and (2) in subsection (i)(1), by striking subparagraph (B) and inserting the following: (B) Elements to assure safe use, if required under subsection (f) for the listed drug. (i) Subject to clause (ii), a drug that is the subject of an abbreviated new drug application may use— (I) a single, shared system with the listed drug under subsection (f); or (II) a different, comparable aspect of the elements to assure safe use under subsection (f). (ii) The Secretary may require a drug that is the subject of an abbreviated new drug application and the listed drug to use a single, shared system under subsection (f), if the Secretary determines that no different, comparable aspect of the elements to assure safe use could satisfy the requirements of subsection (f). .