; considerations (A) Application To be eligible to receive an award under paragraph (1) an entity shall submit an application to the Secretary at such a time, in such manner, and containing such information as the Secretary may reasonably require. (B) Considerations In evaluating the applications in subparagraph (A), the Secretary shall consider the existing infrastructure of the entity that would allow for the timely capture of biospecimens and related clinical and demographic information for children, adolescents, and young adults with cancer. (5) Privacy protections; consent (A) In general The Secretary may not make an award under paragraph (1) to an entity unless the Secretary ensures that such entity— (i) collects biospecimens and associated clinical and demographic information from children and adolescents with appropriate permission from parents or legal guardians in accordance with Federal and State law; and (ii) adheres to strict confidentiality to protect the identity and privacy of patients in accordance with Federal and State law. (B) Consent The Secretary shall establish an appropriate process for achieving consent from the patient, parent, or legal guardian. (6) Single point of access; standard data