; and (ii) showing, for each such service area, an increase equal to or greater than the national increase in such problems, between— (I) 1999; and (II) 2016 or the latest year for which data are available. (B) Information In making the showing described in subparagraph (A)(ii), the eligible entity may use information including data on— (i) the incidence or prevalence of opioid abuse and other substance use disorders; (ii) the per capita drug overdose mortality rate, as determined by the Director of the Centers for Disease Control and Prevention; (iii) the rate of non-fatal hospitalizations related to opioid abuse or another substance use disorder; or (iv) the number of arrests or convictions, or a relevant law enforcement statistic, that reasonably shows an increase in opioid abuse or another substance use disorder. (C) Support for State strategy The eligible entity shall also include in the application information describing how the proposed services and activities support the State’s strategy for addressing problems described in subparagraph (A) in specific regions or across the State, outlaying area, or Tribal entity. (3) Economic and employment conditions demonstrate additional Federal support needed (A) Demonstration An eligible entity shall include in the application information that demonstrates that a high rate of a substance use disorder has caused, or is coincident to, an economic or employment downturn in the service area. (B) Information In making the demonstration described in subparagraph (A), the eligible entity may use information including— (i) documentation of any layoff, announced future layoff, legacy industry decline, decrease in an employment or labor market participation rate, or economic impact, whether or not the result described in this clause is overtly related to a high rate of a substance use disorder