; (ii) the known and estimated flows into the United States from all sources in the calendar year and each of the previous 3 calendar years; (iii) the total amount of known flows that could not be interdicted or disrupted in the calendar year and each of the previous 3 calendar years; (iv) the known and estimated levels of domestic production in the calendar year and each of the previous three calendar years, including the levels of domestic production if the drug is a prescription drug, as determined under the Federal Food, Drug, and Cosmetic Act, for which a listing is in effect under section 202 of the Controlled Substances Act ( 21 U.S.C. 812 )