; and (B) manufactured, imported, distributed, or marketed for use in cosmetics. 617. Treatment of cosmetics based on ingredient lists (a) In general Subject to subsections (b)(5) and (d)(4) of section 616 , a brand owner may only distribute in interstate commerce a cosmetic that meets the safety standard under section 614(a) . (b) Presumption related to the safety of cosmetics (1) In general Subject to paragraph (2) , for purposes of subsection (a) , the Secretary shall presume that the following cosmetics meet the safety standard under section 614(a) : (A) A cosmetic that is made solely of ingredients on the list under section 616(c)(1) (relating to ingredients that are safe without limits). (B) A cosmetic that is made solely of ingredients on the list under section 616(b)(1)(B) (relating to ingredients subject to restrictions) and the use of each of such ingredients in such cosmetic is in compliance with the restrictions on the use of such ingredients specified under section 616(b)(3) . (C) A cosmetic that is made solely of ingredients described under subparagraph (A) and subparagraph (B) . (2) Exceptions The Secretary may require that a brand owner demonstrate that a cosmetic meets the safety standard under section 614(a) (including by requiring that the brand owner conduct safety testing, or request such safety testing from relevant suppliers and manufacturers, of a cosmetic described under paragraph (1) ) if the cosmetic— (A) contains penetration enhancers, sensitizers, estrogenic chemicals, or other similar ingredients; (B) contains ingredients that react with each other or with other substances to form harmful byproducts