; (2) under such program, require that such information be transmitted by such air carriers and other persons at the earliest point practicable prior to loading of such cargo onto an aircraft destined to or transiting through the United States; (3) establish appropriate communications systems with freight forwarders, shippers, and air carriers; (4) establish a system that will allow freight forwarders, shippers, and air carriers to provide shipment level data for air cargo, departing from any location that is inbound to the United States; and (5) coordinate with the Administrator of the Transportation Security Administration to identify opportunities in which the information furnished in compliance with the ACAS Program could be used by the Administrator. (b) Inspection of high-Risk cargo Under the ACAS Program, the Secretary shall ensure that all cargo that has been identified as high risk is inspected— (1) prior to the loading of such cargo onto aircraft at the last point of departure