; and (C) in paragraph (6) (as redesignated by subparagraph (A)), by striking , acting through the Director of the Office of Science of the Department of Energy . (3) Department of Energy High-End computing research and development program Section 3 of the American Super Computing Leadership Act of 2017 ( 15 U.S.C. 5542 ) is amended— (A) in subsection (a)(1), by striking program and inserting coordinated program across the Department ; (B) in subsection (b)(2), by striking , which may and all that follows through architectures ; and (C) by striking subsection (d) and inserting the following: (d) Exascale computing program (1) In general The Secretary shall conduct a research program (referred to in this subsection as the Program ) for exascale computing, including the development of 2 or more exascale computing machine architectures, to promote the missions of the Department. (2) Execution (A) In general In carrying out the Program, the Secretary shall— (i) establish 2 or more National Laboratory partnerships with industry partners and institutions of higher education for the research and development of 2 or more exascale computing architectures across all applicable organizations of the Department; (ii) conduct mission-related codesign activities in developing the exascale computing architectures under clause (i); (iii) develop such advancements in hardware and software technology as are required to fully realize the potential of an exascale production system in addressing Department target applications and solving scientific problems involving predictive modeling and simulation and large scale data analytics and management; (iv) explore the use of exascale computing technologies to advance a broad range of science and engineering