; or (2) that is included on the list under section 506E. (b) Request from sponsors A request to expedite the development and review of an application under subsection (a) shall be submitted by the applicant prior to the submission of such application. (c) Other applications Nothing in this section shall prevent the Secretary from expediting the development and review of other applications as the Secretary determines appropriate. (d) Additional communication The Secretary shall take such actions as are appropriate to expedite the development and review of the application for approval of a drug described in subsection (a), including, as appropriate— (1) holding meetings with the sponsor and the review team throughout the development of the drug prior to submission of the application; (2) providing timely advice to, and interactive communication with, the sponsor regarding the development of the application to ensure that the collection of nonclinical and clinical data necessary for approval is as efficient as practicable; (3) in the case of a complex product, assigning a cross-disciplinary project lead for the review team to facilitate an efficient review of the development program and application, including manufacturing inspections