; or (ii) in the case of a drug for which the average manufacturer price is not available, the manufacturer’s average sales price (as defined in section 1847A(c)(1) of the Social Security Act (42 U.S.C. 1395w-3a(c)(1)). (C) Commerce The term commerce has the meaning given such term in section 4 of the Federal Trade Commission Act ( 15 U.S.C. 44 ). (D) Prescription drug The term prescription drug means any drug subject to section 503(b)(1) of the Federal Food, Drug, and Cosmetic Act ( 21 U.S.C. 353(b)(1) ) which is covered by a Federal health care program (as defined in section 1128B(f) of the Social Security Act (42 U.S.C. 1320a–7b(f))). (E) Price spike (i) In general The term price spike means an increase in the average price in commerce of a prescription drug for which the price spike percentage is equal to or greater than the applicable price increase allowance. (ii) Price spike percentage The price spike percentage is the percentage (if any) by which— (I) the average price of a prescription drug in commerce for the most recently completed calendar year; exceeds (II) the average price of such drug in commerce for the calendar year preceding such year. (iii) Applicable price increase allowance The applicable price increase allowance for any calendar year is the percentage (rounded to the nearest one-tenth of 1 percent) by which the medical care component of the consumer price index for all urban consumers (as published by the Bureau of Labor Statistics) for that year exceeds such component for the preceding calendar year. (F) Price spike revenue (i) In general The price spike revenue for any calendar year is an amount equal to— (I) the gross price spike revenue; minus (II) the adjustment amount. (ii) Gross price spike revenue The gross price spike revenue for any calendar year is an amount equal to the product of— (I) an amount equal to the difference between subclause (I) of subparagraph (E)(ii) and subclause (II) of such subparagraph