; or (II) inadequate grounds exist to support the actions required by the order; or (ii) that the order under paragraph (1) was appropriate as issued. (E) Amendment or vacation of order (i) Amendment In the case of a determination made under subparagraph (D)(i)(I) , the Secretary shall amend the order made under paragraph (1) accordingly. (ii) Vacation In the case of a determination made under subparagraph (D)(i)(II) , the Secretary shall vacate the order made under paragraph (1) . (3) Order to Recall (A) Amendment Except as provided under subsection (d) , if after providing an opportunity for an informal hearing under paragraph (2)(C) , the Secretary determines that the order should be amended to include a recall of the drug with respect to which the order was issued, the Secretary shall amend the order to require a recall. (B) Contents An amended order under subparagraph (A) shall— (i) specify a timetable in which the recall will occur; (ii) require periodic reports to the Secretary describing the progress of the recall; and (iii) provide for notice, including to individuals as appropriate, to persons who may be affected by the recall. In providing for such notice, the Secretary may allow for the assistance of health professionals, State or local officials, or other individuals designated by the Secretary. (C) Nondelegation An amended order under this paragraph shall be ordered by the Secretary or an official designated by the Secretary. An official may not be so designated unless the official is the director of the district under this Act in which the drug involved is located, or is an official senior to such director. (d) Emergency Recall Order (1) In general If the Secretary has credible evidence or information that a drug subject to an order under subsection (c)(1) presents an imminent threat of serious adverse health consequences or death to humans or animals, the Secretary may issue an order requiring any person who distributes such drug— (A) to immediately recall such drug