; (v) the voluntary nature of clinical practice guidelines; (vi) the complexities presented by coinfections relating to symptomology, diagnosis, and treatment, including prudently acting in the patient’s interest in non- or low-incidence States; and (vii) the identification of significant research gaps most impacting diagnosis and treatment, and significant research being conducted to address those gaps. (E) Process for developing physician education program The Secretary of Health and Human Services shall— (i) conduct a public meeting to solicit input for the design of the physician education program under subparagraph (D); (ii) give the public notice of such meeting at least 45 days in advance; (iii) also solicit input on the design of the physician education program from the Tick-Borne Disease Working Group; (iv) publish a proposed syllabus for the physician education program not more than 120 days after the public meeting; (v) allow for a 60-day public comment period before publishing such syllabus in final form