1. Short title This Act may be cited as the Rare disease Advancement, Research, and Education Act of 2018 or the RARE Act of 2018 . 2. Improving programs and activities of HHS concerning rare diseases and conditions (a) NIH Paragraph (1) of section 402A(a) of the Public Health Service Act ( 42 U.S.C. 282a(a) ) is amended by adding at the end the following: In addition to the amounts authorized to be appropriated by the preceding sentence, there is authorized to be appropriated $10,000,000 for each of fiscal years 2019 through 2023 for carrying out section 481A (relating to rare disease regional centers of excellence). . (b) CDC surveillance of rare diseases and conditions Title III of the Public Health Service Act is amended by inserting after section 317T of such Act ( 42 U.S.C. 247b–22 ) the following: 317U CDC surveillance of rare diseases and conditions (a) In General The Secretary, acting through the Director of the Centers for Disease Control and Prevention and in coordination with other agencies as the Secretary determines, shall, as appropriate— (1) enhance and expand infrastructure and activities to track the epidemiology of rare diseases and conditions; and (2) incorporate information obtained through such activities into an integrated surveillance system, which may consist of or include a registry, to be known as the National Rare Disease or Condition Surveillance System. (b) Research The Secretary shall ensure that the National Rare Disease or Condition Surveillance System is designed in a manner that facilitates further research on rare diseases and conditions. (c) Content In carrying out subsection (a), the Secretary— (1) shall provide for the collection and storage of information on the incidence and prevalence of rare diseases and conditions in the United States