Sertoli cell nodule
Introduction A '''Sertoli cell nodule''' is a benign proliferation of Sertoli cells that arises in association with cryptorchidism (undescended testis). They are not composed of a clonal cell population, i.e. neoplastic; thus, technically, they should not be called an ''adenoma''.__TOC__
Pathology Sertoli cell nodules are unencapsulated nodules that consist of:# cells arranged in well-formed tubules (that vaguely resemble immature Sertoli cells), with# bland hyperchromatic oval/round nuclei that are stratified, and# may contain eosinophilic (hyaline) blob in lumen (centre).Image:Sertoli cell nodule intermed mag.jpg|Micrograph of a Sertoli cell nodule. H&E stain.Image:Sertoli cell nodule low mag.jpg|Micrograph of a Sertoli cell nodule. H&E stain.
References
Further reading * '' Testis, Sex Cord Stromal Tumor'' - eMedicine. * *