Bromocyclohexane
Introduction '''Bromocyclohexane''' (also called '''cyclohexyl bromide''', abbreviated '''CXB''') is an organic compound with the chemical formula .
Uses and reactions It is used to match the refractive index of PMMA for example in confocal microscopy of colloids. A mixture of ''cis''-decalin and CXB can simultaneously match optical index and density of PMMA. Due to the moderate dielectric constant of CXB (ε = 7.9 ), PMMA acquires charges that can be screened by the addition of salt (e.g. tetrabutyl ammonium bromide), leading to a very good approximation of colloidal hard sphere. A drawback is that CXB is a good solvent for PMMA, causing it to swell over time, which may lead to a poor determination of particle radii and determination of solid volume fraction.It is a standard coupling partner of cross coupling reactions. Similarly, cyclohexyl bromide is a standard alkylating agent.
Synthesis Bromocyclohexane can be prepared by the free radical bromination of cyclohexane.
Safety Bromocyclohexane is an alkylating agent.
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