Nuage (cell biology)
Introduction '''Nuage''' are ''Drosophila melanogaster'' germline granules. Nuage are the hallmark of ''Drosophila melanogaster'' germline cells, which have an electron-dense perinuclear structure and can silence the selfish genetic elements in ''Drosophila melanogaster''. The term 'Nuage' comes from the French word for 'cloud', as they appear as nebulous electron-dense bodies by electron microscopy. They are found in nurse cells of the developing ''Drosophila melanogaster'' egg chamber and are composed of various types of proteins, including RNA-helicases, Tudor domain proteins, Piwi-clade Argonaute proteins, in addition to a PRMT5 methylosome composed of Capsuléen  and its co-factor, Valois (MEP50).See piRNA for more information.
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