5-Fluoro-DMT
Introduction '''5-Fluoro-''N'',''N''-dimethyltryptamine''' ('''5-fluoro-DMT''', '''5F-DMT''') is a tryptamine derivative related to compounds such as 5-bromo-DMT and 5-MeO-DMT. Fluorination of psychedelic tryptamines either reduces or has little effect on 5-HT2A/C receptor affinity or intrinsic activity, although 6-fluoro-DET is inactive as a psychedelic despite acting as a 5-HT2A agonist (cf. lisuride), while 4-fluoro-5-methoxy-DMT is a much stronger agonist at 5-HT1A than 5-HT2A.
See also * 5-Fluoro-AMT* 5-Fluoro-DET* 5-Fluoro-MET* 6-fluoro-AMT* 6-Fluoro-DMT* 4-fluoro-5-methoxy-DMT* 6-Fluoro-DET( 6-Fluoro-DET)* O-4310*It's worth noting that GR-159897 is based on the same structure.
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