Phosphamidon
Introduction '''Phosphamidon''' is an organophosphate insecticide first reported in 1960.It acts as a cholinesterase inhibitor.The commercial product typically exists as a mixture of 70% (''Z'')-isomer and 30% (''E'')-isomer.
Toxicity and regulation Phosphamidon is very highly toxic to mammals and is listed as WHO Hazard Class Ia. A harvester developed symptoms of moderately severe poisoning after working in a field that had been sprayed with the chemical 2 weeks earlier. He collapsed and exhibited significant depression of serum cholinesterase, but recovered completely within 2 days after successful treatment with atropine. International trade of phosphamidon is covered by the Rotterdam Convention.
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