4-Hydroxybenzaldehyde
Introduction '''4-Hydroxybenzaldehyde''' (2-hydroxybenzaldehyde) is an organic compound with the formula . Along with 2-hydroxybenzaldehyde and 3-hydroxybenzaldehyde, it is one of the three isomers of hydroxybenzaldehyde.
Synthesis, reactions, uses 4-Hydroxybenzaldehyde is prepared by reaction of phenol with chloroform, which gives isomeric hydroxybenzal chlorides. Hydrolysis of the C-Cl bonds gives the aldehyde.4-Hydroxybenzaldehyde is a precursor to 4-hydroxyphenylglycine, a precursor to penicillins. In the Dakin oxidation, 4-hydroxybenzaldehyde reacts with hydrogen peroxide in base to form hydroquinone.
Metabolism and occurrence p-Hydroxybenzaldehyde dehydrogenase is an enzyme found in carrots (''Daucus carota'').4-Hydroxybenzaldehyde is found in the orchids ''Gastrodia elata'', ''Galeola faberi'', and the ''Vanilla'' orchids.
See also * Salicylaldehyde (2-hydroxybenzaldehyde)
References
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