## Protocol Section
### Identification Module
**NCT ID:** NCT06437327

**Brief Title:** Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome

**Official Title:** Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome

#### Organization Study ID Info
**ID:** FUI/CTR/2024/10
#### Organization
**Class:** OTHER
**Full Name:** Foundation University Islamabad
### Status Module
#### Completion Date
**Date:** 2024-06-20

**Type:** ESTIMATED

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2024-05-31

**Type:** ESTIMATED

**Last Update Submit Date:** 2024-05-27

**Overall Status:** RECRUITING

#### Primary Completion Date
**Date:** 2023-11-20

**Type:** ACTUAL

#### Start Date
**Date:** 2023-07-15

**Type:** ACTUAL

**Status Verified Date:** 2024-05

#### Study First Post Date
**Date:** 2024-05-31
**Type:** ESTIMATED
**Study First Submit Date:** 2024-05-27
**Study First Submit QC Date:** 2024-05-27
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Foundation University Islamabad

#### Responsible Party

**Type:** SPONSOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** This study is a randomized controlled trial and the purpose of this study is to compare the effects between active release technique and hold relax technique in patients with Piriformis syndrome.

**Detailed Description:** The purpose of this study is to compare the effects between active release technique and hold relax technique in patients with piriformis syndrome pain, range of motion, and functional disability, in adults (age: 25-55 years)

1. Numeric pain rating scale
2. Goniometer
3. Oswestry Disability Questionairre Data will be collected before and after the intervention protocol for each participant.

Data collection procedure: Participants of interest would be approached and explained about the research. Informed written consent will be taken. Pre and post-intervention scores will be recorded.

### Conditions Module

**Conditions:**

- Piriformis Syndrome

### Design Module

#### Design Info

**Allocation:** RANDOMIZED

**Intervention Model:** PARALLEL

**Intervention Model Description:** Randomized Controlled Trial

##### Masking Info

**Masking:** NONE

**Primary Purpose:** TREATMENT

#### Enrollment Info

**Count:** 40

**Type:** ESTIMATED

**Phases:**

- NA

**Study Type:** INTERVENTIONAL

### Arms Interventions Module

#### Arm Group 1

**Description:** Hot pack for 10 minutes Interferential Current (IFC) for 10 minutes Active release technique is applied (patient is prone lying with knee flexed, Pressure is applied on taut band and patient is asked to move the leg in internal rotation to achieve maximal lengthening) Repetitions 5 to 7 times hold for 5 to 20 seconds

**Intervention Names:**

- Procedure: Electrotherapy

- Procedure: Active release technique

**Label:** Experimiental Group 1

**Type:** EXPERIMENTAL

#### Arm Group 2

**Description:** Hot pack for 10 minutes Interferential Current (IFC) for 10 minutes Hold relax technique This technique is applied while the patient is in supine lying with one leg crossed over the other Patient is instructed to contract the piriformis against the manual resistance for 5 to 10 secs Then 15 secs of passive stretch is given repetitions x 5 times

**Intervention Names:**

- Procedure: Electrotherapy

- Procedure: Hold relax technique

**Label:** Experimental Group 2

**Type:** EXPERIMENTAL

### Interventions

#### Intervention 1

**Arm Group Labels:**

- Experimental Group 2

- Experimiental Group 1

**Description:** Hot pack for 10 minutes Interferential Current (IFC) for 10 minutes

**Name:** Electrotherapy

**Type:** PROCEDURE

#### Intervention 2

**Arm Group Labels:**

- Experimiental Group 1

**Description:** Active release technique is applied (patient is prone lying with knee flexed, Pressure is applied on taut band and patient is asked to move the leg in internal rotation to achieve maximal lengthening) Repetitions 5 to 7 times hold for 5 to 20 seconds

**Name:** Active release technique

**Type:** PROCEDURE

#### Intervention 3

**Arm Group Labels:**

- Experimental Group 2

**Description:** This technique is applied while the patient is in supine lying with one leg crossed over the other Patient is instructed to contract the piriformis against the manual resistance for 5 to 10 secs Then 15 secs of passive stretch is given repetitions x 5 times

**Name:** Hold relax technique

**Type:** PROCEDURE

### Outcomes Module

#### Primary Outcomes

**Description:** Numeric Pain Rating Scale (NPRS): ICC (0.93-0.96).It has a scale of 0-10 or 0-100 points and can be given verbally or in writing.

**Measure:** Pain intensity

**Time Frame:** 2 weeks

**Description:** Physical Function will be measured using Oswestry disability Questionnaire

**Measure:** Physical Function using Oswestry disability Questionnaire

**Time Frame:** 2 weeks

**Description:** Hip internal rotation using Goniometer

**Measure:** Hip internal rotation range of motion

**Time Frame:** 2 weeks

### Eligibility Module

**Eligibility Criteria:** Inclusion criteria:

* Gender: Both male and female
* Individuals aged 25-55 years
* Tenderness to palpation over sciatic foramen
* Positive FAIR Test.

Exclusion criteria :

* History of hip, pelvic, or Femoral fractures.
* Malignancies.
* Avascular necrosis of Femoral head.
* Inflammatory conditions (e.g. Rheumatoid Arthritis)

**Maximum Age:** 55 Years

**Minimum Age:** 25 Years

**Sex:** ALL

**Standard Ages:**

- ADULT

### Contacts Locations Module

#### Central Contacts

**Contact 1:**

**Email:** qasim111298@gmail.com

**Name:** Mohammad Ali, MS-MSKPT*

**Phone:** 03415161695

**Role:** CONTACT

#### Locations

**Location 1:**

**City:** Rawalpindi

**Contacts:**

***Contact 1:***

- **Email:** furqan.hassan@fui.edu.pk

- **Name:** Furqan Hassan, MS-OMPT,PHD*

- **Phone:** 03334056768

- **Role:** CONTACT

**Country:** Pakistan

**Facility:** Foundation University College of Physical Therapy

**State:** Punjab

**Status:** RECRUITING

**Zip:** 46000

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000004194

- Term: Disease

- ID: D000010335

- Term: Pathologic Processes

- ID: D000020426

- Term: Sciatic Neuropathy

- ID: D000020422

- Term: Mononeuropathies

- ID: D000010523

- Term: Peripheral Nervous System Diseases

- ID: D000009468

- Term: Neuromuscular Diseases

- ID: D000009422

- Term: Nervous System Diseases

- ID: D000009408

- Term: Nerve Compression Syndromes

- ID: D000009437

- Term: Neuralgia

- ID: D000010146

- Term: Pain

- ID: D000009461

- Term: Neurologic Manifestations

- ID: D000017699

- Term: Pelvic Pain

### Condition Browse Module - Browse Branches

- Abbrev: BC10

- Name: Nervous System Diseases

- Abbrev: BC23

- Name: Symptoms and General Pathology

- Abbrev: All

- Name: All Conditions

- Abbrev: BC16

- Name: Diseases and Abnormalities at or Before Birth

- Abbrev: Rare

- Name: Rare Diseases

### Condition Browse Module - Browse Leaves

- ID: M28404

- Name: Piriformis Muscle Syndrome

- Relevance: HIGH

- As Found: Piriformis Syndrome

- ID: M16355

- Name: Syndrome

- Relevance: HIGH

- As Found: Syndrome

- ID: M22222

- Name: Sciatic Neuropathy

- Relevance: LOW

- As Found: Unknown

- ID: M22218

- Name: Mononeuropathies

- Relevance: LOW

- As Found: Unknown

- ID: M13432

- Name: Peripheral Nervous System Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M12411

- Name: Neuromuscular Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M12352

- Name: Nerve Compression Syndromes

- Relevance: LOW

- As Found: Unknown

- ID: M5853

- Name: Charcot-Marie-Tooth Disease

- Relevance: LOW

- As Found: Unknown

- ID: M18092

- Name: Hereditary Sensory and Motor Neuropathy

- Relevance: LOW

- As Found: Unknown

- ID: M12381

- Name: Neuralgia

- Relevance: LOW

- As Found: Unknown

- ID: M13066

- Name: Pain

- Relevance: LOW

- As Found: Unknown

- ID: M12404

- Name: Neurologic Manifestations

- Relevance: LOW

- As Found: Unknown

- ID: M19918

- Name: Pelvic Pain

- Relevance: LOW

- As Found: Unknown

- ID: T4568

- Name: Piriformis Syndrome

- Relevance: HIGH

- As Found: Piriformis Syndrome

- ID: T1081

- Name: Charcot-Marie-Tooth Disease

- Relevance: LOW

- As Found: Unknown

- ID: T2761

- Name: Hereditary Motor and Sensory Neuropathy

- Relevance: LOW

- As Found: Unknown

- ID: T2766

- Name: Hereditary Neuropathy With Liability to Pressure Palsies

- Relevance: LOW

- As Found: Unknown

- ID: T5067

- Name: Roussy Levy Syndrome

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000055958

- Term: Piriformis Muscle Syndrome

- ID: D000013577

- Term: Syndrome

### Misc Info Module

- Version Holder: 2024-05-31
