## Protocol Section
### Identification Module
**NCT ID:** NCT06427070

**Brief Title:** Effectiveness of Two Intracanal Irrigation Solutions

**Official Title:** Effectiveness of Two Intracanal Irrigation Solutions Delivered Through Cryotherapy on Post-Endodontic Pain Relieve. A Randomized Clinical Trial

#### Organization Study ID Info
**ID:** CHX 2024
#### Organization
**Class:** OTHER
**Full Name:** Misr University for Science and Technology
### Status Module
#### Completion Date
**Date:** 2024-06-01

**Type:** ESTIMATED

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2024-05-23

**Type:** ACTUAL

**Last Update Submit Date:** 2024-05-18

**Overall Status:** NOT_YET_RECRUITING

#### Primary Completion Date
**Date:** 2024-05-30

**Type:** ESTIMATED

#### Start Date
**Date:** 2024-05-23

**Type:** ESTIMATED

**Status Verified Date:** 2024-05

#### Study First Post Date
**Date:** 2024-05-23
**Type:** ACTUAL
**Study First Submit Date:** 2024-05-14
**Study First Submit QC Date:** 2024-05-18
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Misr University for Science and Technology

#### Responsible Party

**Investigator Affiliation:** Misr University for Science and Technology

**Investigator Full Name:** Manal Mohamed

**Investigator Title:** Lecturer at Misr university

**Type:** PRINCIPAL_INVESTIGATOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

**Is US Export:** False

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** The aim of the present clinical trial is to investigate and compare the effect of crayotherapy utilizing two intra-canal final irrigating solutions on postoperative pain.

**Detailed Description:** 1. st: Comparison of pain reduction algorism after cryotherapy using the two tested irrigating materials
2. nd. Number and frequency of analgesics taken for pain relief during one week postoperative

### Conditions Module

**Conditions:**

- Irreversible Pulpitis

**Keywords:**

- Pulpitis

- CHX

- Saline

### Design Module

#### Design Info

**Allocation:** NA

**Intervention Model:** SINGLE_GROUP

##### Masking Info

**Masking:** NONE

**Primary Purpose:** TREATMENT

#### Enrollment Info

**Count:** 1

**Type:** ESTIMATED

**Phases:**

- NA

**Study Type:** INTERVENTIONAL

### Arms Interventions Module

#### Arm Group 1

**Description:** Group 1 sodium hypochlorite Group 2 saline Group 3 chlorohexidine

**Intervention Names:**

- Other: Irrigating solution

**Label:** Irrigating solutions

**Type:** EXPERIMENTAL

### Interventions

#### Intervention 1

**Arm Group Labels:**

- Irrigating solutions

**Description:** Saline, sodium hypochlorite, chlorohexidine

**Name:** Irrigating solution

**Other Names:**

- Chlorohexidine

**Type:** OTHER

### Outcomes Module

#### Primary Outcomes

**Description:** pain scale Comparison of the 2 selected irrigating solutions

**Measure:** pain scale

**Time Frame:** 1 week

**Description:** Frequency of analgesics for pain relief

**Measure:** Analgesics Frequency

**Time Frame:** 1 week

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* Case diagnosed as having symptomatic irreversible pulpitis with symptomatic apical periodontitis
* Patients requiring emergency RCT
* Pre-operative pain score 7 on Numerical Rating (NRS) scale
* Middle aged males (25-50)
* Medical profile ASA1
* Willing to sign the consent form
* Willing to answer our call for one week period

Exclusion Criteria:

* Females
* Medical conditions above ASA1
* Multi-rooted teeth
* Patients younger or older than (25-50)

**Healthy Volunteers:** True

**Maximum Age:** 50 Years

**Minimum Age:** 25 Years

**Sex:** MALE

**Standard Ages:**

- ADULT

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000003788

- Term: Dental Pulp Diseases

- ID: D000014076

- Term: Tooth Diseases

- ID: D000009057

- Term: Stomatognathic Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC07

- Name: Mouth and Tooth Diseases

- Abbrev: All

- Name: All Conditions

- Abbrev: BC23

- Name: Symptoms and General Pathology

### Condition Browse Module - Browse Leaves

- ID: M14525

- Name: Pulpitis

- Relevance: HIGH

- As Found: Pulpitis

- ID: M13066

- Name: Pain

- Relevance: LOW

- As Found: Unknown

- ID: M6984

- Name: Dental Pulp Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M16831

- Name: Tooth Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M12017

- Name: Stomatognathic Diseases

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000011671

- Term: Pulpitis

### Intervention Browse Module - Browse Branches

- Abbrev: Antipy

- Name: Antipyretics

- Abbrev: Analg

- Name: Analgesics

- Abbrev: All

- Name: All Drugs and Chemicals

- Abbrev: Infe

- Name: Anti-Infective Agents

- Abbrev: PhSol

- Name: Pharmaceutical Solutions

### Intervention Browse Module - Browse Leaves

- ID: M2340

- Name: Acetaminophen

- Relevance: LOW

- As Found: Unknown

- ID: M15775

- Name: Sodium Hypochlorite

- Relevance: LOW

- As Found: Unknown

- ID: M44557

- Name: Eusol

- Relevance: LOW

- As Found: Unknown

- ID: M21860

- Name: Pharmaceutical Solutions

- Relevance: LOW

- As Found: Unknown

### Misc Info Module

- Version Holder: 2024-05-31
