## Protocol Section
### Identification Module
**NCT ID:** NCT06421727

**Brief Title:** Rehabilitation Of Balance Function In Patients With Persistent Postural Perceptual Dizziness.

**Official Title:** Rehabilitation Of Balance Function In Patients With Persistent Postural Perceptual Dizziness: A Longitudinal Study

#### Organization Study ID Info
**ID:** Soh-Med-24-01-06MD
#### Organization
**Class:** OTHER
**Full Name:** Sohag University
### Status Module
#### Completion Date
**Date:** 2026-03-01

**Type:** ESTIMATED

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2024-05-20

**Type:** ACTUAL

**Last Update Submit Date:** 2024-05-17

**Overall Status:** NOT_YET_RECRUITING

#### Primary Completion Date
**Date:** 2026-01-01

**Type:** ESTIMATED

#### Start Date
**Date:** 2024-06-30

**Type:** ESTIMATED

**Status Verified Date:** 2024-05

#### Study First Post Date
**Date:** 2024-05-20
**Type:** ACTUAL
**Study First Submit Date:** 2024-04-20
**Study First Submit QC Date:** 2024-05-17
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Sohag University

#### Responsible Party

**Investigator Affiliation:** Sohag University

**Investigator Full Name:** Nada Mostafa Abdelhamid

**Investigator Title:** Assistant lecturer

**Type:** PRINCIPAL_INVESTIGATOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** Rehabilitation Of Balance Function In Patients With Persistent Postural Perceptual Dizziness: A longitudinal Study

**Detailed Description:** this study will be conducted to show the long term effect of combined vestibular rehabilitation incorporating optokinetic stimulation and virtual reality exercises on persistent postural perceptual dizziness patients.

Aim:1.Evaluate the balance control function in patients with persistent postural perceptual dizziness using computerized dynamic posturography.

2.To study effect of rehabilitation using optokinetic stimulation and virtual reality on persistent postural perceptual dizziness patients.

3.To follow up patients after the vestibular rehabilitation therapy to study the persistence of improvement" if any" in patients with persistent postural perceptual dizziness .

Type of the study : prospective cohort and longitudinal study. Sources of data : Audio-vestibular medicine unit , Sohag University Hospital. Study group : consists of 36 patients age ranged from 18-65 years suffering from symptoms of persistent postural perceptual vertigo.

All subjects will be submitted to:

A- Detailed medical history, full history of dizziness. B-Acoustic impedance test. C-Basic audiological evaluation. D- Vestibular assessment.

### Conditions Module

**Conditions:**

- Persistent Postural Perceptual Dizziness

### Design Module

#### Design Info

**Allocation:** NA

**Intervention Model:** SINGLE_GROUP

**Intervention Model Description:** combined vestibular rehabilitation incorporating optokinetic stimulation and virtual reality exercises on persistent postural perceptual dizziness patients.

##### Masking Info

**Masking:** NONE

**Primary Purpose:** TREATMENT

#### Enrollment Info

**Count:** 36

**Type:** ESTIMATED

**Phases:**

- NA

**Study Type:** INTERVENTIONAL

### Arms Interventions Module

#### Arm Group 1

**Description:** combined vestibular rehabilitation incorporating optokinetic stimulation and virtual reality exercises (by device Virtual reality system(Meta Quest 2_Advanced All-In-One Virtual Reality Headset_ 128 GB)) on persistent postural perceptual dizziness patients.

**Intervention Names:**

- Other: Rehabilitation by optokinetic stimulation and virtual reality exercises .

**Label:** Rehabilitation by optokinetic stimulation and virtual reality exercises .

**Type:** OTHER

### Interventions

#### Intervention 1

**Arm Group Labels:**

- Rehabilitation by optokinetic stimulation and virtual reality exercises .

**Description:** Rehabilitation by optokinetic stimulation and virtual reality exercises(by deviceVirtual reality system(Meta Quest 2_Advanced All-In-One Virtual Reality Headset_ 128 GB)).

**Name:** Rehabilitation by optokinetic stimulation and virtual reality exercises .

**Type:** OTHER

### Outcomes Module

#### Primary Outcomes

**Description:** Improvement of dizziness measured by Computerized dynamic posturography:6 conditions, the maximum handicap score 0/6 and the minimum 6/6.

**Measure:** Rehabilitation Of Balance Function In Patients With Persistent Postural Perceptual Dizziness : A longitudinal Study

**Time Frame:** 2 years

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* Age: from 18 years to 65 years old.
* Gender: males and females.
* Can withstand and willing to undergo repeated vestibular rehabilitation therapy .\*No history of any disease required to give treatment that could affect results.

Exclusion Criteria:

* Neurological disorders, paresis, paralysis, motor disorder, ataxia, brain mass, multiple sclerosis and stroke with grade 4 muscle power or below.
* Otological disorders e.g. middle ear pathology (chronic suppurative otitis media, Tumor).
* Psychiatric disorders e.g. Schizophrenia and endogenous depression.
* Severely ill patients who would not tolerate vestibular rehabilitation therapy .

**Healthy Volunteers:** True

**Maximum Age:** 65 Years

**Minimum Age:** 18 Years

**Sex:** ALL

**Standard Ages:**

- ADULT

- OLDER_ADULT

### Contacts Locations Module

#### Central Contacts

**Contact 1:**

**Email:** nadamostafaelhakeem@yahoo.com

**Name:** nada elhakeem

**Phone:** 01000401121

**Role:** CONTACT

**Contact 2:**

**Email:** dmostafa4@yahoo.com

**Name:** mostafa yossif

**Phone:** 01001313395

**Role:** CONTACT

#### Overall Officials

**Official 1:**

**Affiliation:** sohag university hospital

**Name:** Maha Ahmed

**Role:** STUDY_CHAIR

### IPD Sharing Statement Module

**IPD Sharing:** NO

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000012678

- Term: Sensation Disorders

- ID: D000009461

- Term: Neurologic Manifestations

- ID: D000015837

- Term: Vestibular Diseases

- ID: D000007759

- Term: Labyrinth Diseases

- ID: D000004427

- Term: Ear Diseases

- ID: D000010038

- Term: Otorhinolaryngologic Diseases

- ID: D000009422

- Term: Nervous System Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC09

- Name: Ear, Nose, and Throat Diseases

- Abbrev: BC10

- Name: Nervous System Diseases

- Abbrev: BC23

- Name: Symptoms and General Pathology

- Abbrev: All

- Name: All Conditions

### Condition Browse Module - Browse Leaves

- ID: M17462

- Name: Vertigo

- Relevance: HIGH

- As Found: Dizziness

- ID: M7420

- Name: Dizziness

- Relevance: HIGH

- As Found: Dizziness

- ID: M15490

- Name: Sensation Disorders

- Relevance: LOW

- As Found: Unknown

- ID: M12404

- Name: Neurologic Manifestations

- Relevance: LOW

- As Found: Unknown

- ID: M18387

- Name: Vestibular Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M10779

- Name: Labyrinth Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M10782

- Name: Labyrinthitis

- Relevance: LOW

- As Found: Unknown

- ID: M7601

- Name: Ear Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M12961

- Name: Otorhinolaryngologic Diseases

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000014717

- Term: Vertigo

- ID: D000004244

- Term: Dizziness

### Misc Info Module

- Version Holder: 2024-05-31
