## Protocol Section
### Identification Module
**NCT ID:** NCT04406779

**Brief Title:** The Frequency of Thyroid Diseases in Women With Breast Cancer

**Official Title:** The Frequency of Thyroid Diseases in Women With Breast Cancer

#### Organization Study ID Info
**ID:** UsakU-Cevdet1
#### Organization
**Class:** OTHER
**Full Name:** Uşak University
### Status Module
#### Completion Date
**Date:** 2017-03-31

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2020-05-28

**Type:** ACTUAL

**Last Update Submit Date:** 2020-05-22

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2017-03-31

**Type:** ACTUAL

#### Start Date
**Date:** 2016-03-01

**Type:** ACTUAL

**Status Verified Date:** 2020-05

#### Study First Post Date
**Date:** 2020-05-28
**Type:** ACTUAL
**Study First Submit Date:** 2020-05-22
**Study First Submit QC Date:** 2020-05-22
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Uşak University

#### Responsible Party

**Investigator Affiliation:** Uşak University

**Investigator Full Name:** Cevdet Duran

**Investigator Title:** M.D.

**Type:** PRINCIPAL_INVESTIGATOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

### Description Module

**Brief Summary:** Breast cancer and thyroid disorders are important health challenges commonly encountered in women. The relationship between both conditions still remains unknown. In this study, the frequency of thyroid diseases was investigated in breast cancer patients

### Conditions Module

**Conditions:**

- Breast Cancer

- Thyroid Diseases

### Design Module

#### Design Info

**Observational Model:** CASE_CONTROL

**Time Perspective:** PROSPECTIVE

#### Enrollment Info

**Count:** 160

**Type:** ACTUAL

**Study Type:** OBSERVATIONAL

### Arms Interventions Module

#### Arm Group 1

**Description:** Patients with breast cancer

**Intervention Names:**

- Device: thyroid USG was perform, blood samples were taken for the meausurement of thyroid hormone and autoantibodies

**Label:** Patients with breast cancer

#### Arm Group 2

**Description:** Healthy patients without breast cancer

**Intervention Names:**

- Device: thyroid USG was perform, blood samples were taken for the meausurement of thyroid hormone and autoantibodies

**Label:** Control

### Interventions

#### Intervention 1

**Arm Group Labels:**

- Control

- Patients with breast cancer

**Description:** thyroid USG was perform, blood samples were taken for the meausurement of thyroid hormone and autoantibodies

**Name:** thyroid USG was perform, blood samples were taken for the meausurement of thyroid hormone and autoantibodies

**Type:** DEVICE

### Outcomes Module

#### Primary Outcomes

**Measure:** to investigate the frequency of thyroid diseases in breast cancer patients.

**Time Frame:** 1 year

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* women, the age between 18-65 years who were diagnosed with breast cancer, but not underwent surgery, radiotherapy or chemothreapy were included into the study

Exclusion Criteria:

* Those with pregnancy, known liver and renal failure, the history of any malignancy other than breast cancer, undergoing a surgical operation due to breast cancer, also those receiving chemotherapy/radiotherapy for the same reason or undergoing partial or complete thyroid surgery or a surgical operation within the past 6 months, and also the patients taking oral anti-diabetic medication, insulin, steroids, thiazide, anti-psychotics and immuno-suppressive medicines affecting the levels of blood glucose, insulin and IR, smokers and those consuming alcohol were excluded

**Gender Based:** True

**Maximum Age:** 65 Years

**Minimum Age:** 18 Years

**Sampling Method:** PROBABILITY_SAMPLE

**Sex:** FEMALE

**Standard Ages:**

- ADULT

- OLDER_ADULT

**Study Population:** women, aged between 18-65 years who were diagnosed with breast cancer, but not underwent surgery, radiotherapy or chemothreapy were included into the study as patients groups. Age matched healthy controls were enrolled as controls.

### IPD Sharing Statement Module

**IPD Sharing:** NO

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000009371

- Term: Neoplasms by Site

- ID: D000009369

- Term: Neoplasms

- ID: D000001941

- Term: Breast Diseases

- ID: D000012871

- Term: Skin Diseases

- ID: D000004700

- Term: Endocrine System Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC04

- Name: Neoplasms

- Abbrev: BC17

- Name: Skin and Connective Tissue Diseases

- Abbrev: All

- Name: All Conditions

- Abbrev: BC19

- Name: Gland and Hormone Related Diseases

### Condition Browse Module - Browse Leaves

- ID: M5220

- Name: Breast Neoplasms

- Relevance: HIGH

- As Found: Breast Cancer

- ID: M16718

- Name: Thyroid Diseases

- Relevance: HIGH

- As Found: Thyroid Diseases

- ID: M5218

- Name: Breast Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M15674

- Name: Skin Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M7862

- Name: Endocrine System Diseases

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000001943

- Term: Breast Neoplasms

- ID: D000013959

- Term: Thyroid Diseases

### Intervention Browse Module - Ancestors

- ID: D000006730

- Term: Hormones, Hormone Substitutes, and Hormone Antagonists

- ID: D000045505

- Term: Physiological Effects of Drugs

- ID: D000007155

- Term: Immunologic Factors

### Intervention Browse Module - Browse Branches

- Abbrev: All

- Name: All Drugs and Chemicals

### Intervention Browse Module - Browse Leaves

- ID: M4625

- Name: Autoantibodies

- Relevance: HIGH

- As Found: Relate

- ID: M9789

- Name: Hormones

- Relevance: HIGH

- As Found: Loss

- ID: M9788

- Name: Hormone Antagonists

- Relevance: LOW

- As Found: Unknown

- ID: M10201

- Name: Immunologic Factors

- Relevance: LOW

- As Found: Unknown

### Intervention Browse Module - Meshes

- ID: D000006728

- Term: Hormones

- ID: D000001323

- Term: Autoantibodies

### Misc Info Module

- Version Holder: 2024-05-24
