## Protocol Section
### Identification Module
**NCT ID:** NCT02582879

**Acronym:** informCLL

**Brief Title:** informCLL™: A Disease Registry for Patients With Chronic Lymphocytic Leukemia

**Official Title:** informCLL™: A Disease Registry for Patients With Chronic Lymphocytic Leukemia

#### Organization Study ID Info
**ID:** PCYC-1134M-CA
#### Organization
**Class:** INDUSTRY
**Full Name:** Pharmacyclics LLC.
### Status Module
#### Completion Date
**Date:** 2021-07-21

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2022-07-22

**Type:** ACTUAL

**Last Update Submit Date:** 2022-07-19

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2021-07-21

**Type:** ACTUAL

#### Start Date
**Date:** 2015-09

**Status Verified Date:** 2022-07

#### Study First Post Date
**Date:** 2015-10-21
**Type:** ESTIMATED
**Study First Submit Date:** 2015-09-08
**Study First Submit QC Date:** 2015-10-19
### Sponsor Collaborators Module

#### Collaborators

**Class:** INDUSTRY

**Name:** Janssen, LP

#### Lead Sponsor

**Class:** INDUSTRY

**Name:** Pharmacyclics LLC.

#### Responsible Party

**Type:** SPONSOR

### Oversight Module

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** The study is designed as a multicenter, prospective, observational registry of CLL/SLL patients who are initiating approved oral kinase inhibitors, BCL-2 inhibitors or other approved anti-CLL therapies/regimens. The study will characterize treatment patterns and their association with patient characteristics, healthcare resource utilization, and clinical outcomes, as well as patient-reported outcome (PRO) measures.

**Detailed Description:** This multicenter, prospective, observational registry of CLL patients is designed to characterize and describe treatment patterns for those initiating treatment with approved oral kinase inhibitors and other approved anti-CLL therapies/ regimens. The registry will provide information on regimens used to treat first-line and later lines of CLL as well as the sequencing of treatment regimens. The registry will also evaluate the association of these treatment patterns with patient characteristics, healthcare resource utilization, and functional outcomes including patient-reported HRQoL. These data will provide information to physicians that may help guide clinical practice and appropriate use of therapies, and will also provide information on HRQoL and healthcare resource utilization that will be of interest to healthcare decision makers.

### Conditions Module

**Conditions:**

- Chronic Lymphocytic Leukemia (CLL)

**Keywords:**

- Chronic Lymphocytic Leukemia

- CLL

- Small Lymphocytic Leukemia

- SLL

### Design Module

#### Bio Spec

**Description:** blood samples

**Retention:** SAMPLES_WITH_DNA

#### Design Info

**Observational Model:** COHORT

**Time Perspective:** PROSPECTIVE

#### Enrollment Info

**Count:** 1504

**Type:** ACTUAL

**Patient Registry:** True

**Study Type:** OBSERVATIONAL

**Target Duration:** 2 Years

### Arms Interventions Module

#### Arm Group 1

**Description:** Patients with CLL/SLL in a real-world setting initiating treatment with approved oral kinase inhibitors, BCL-2 inhibitors and other approved anti-CLL therapies/regimens.

**Label:** Patient with CLL/SLL

### Outcomes Module

#### Primary Outcomes

**Description:** - Summarize baseline characteristics of study participants

**Measure:** Summarize baseline characteristics of study population, among CLL patients in a real-world setting

**Time Frame:** up to 7 years

**Description:** * Summarize number of participants on various initial and subsequent treatments
* Summarize proportion of patients switching therapies at each follow up time point

**Measure:** Summarize treatment patterns among CLL patients in a real-world setting

**Time Frame:** up to 7 years

**Description:** - Measures of effectiveness used will include survival status, ECOG Health status, response assessments as evaluated by the investigator such as: complete response, partial response, stable disease, progressive disease

**Measure:** Summarize clinical outcomes among CLL patients in a real-world setting

**Time Frame:** up to 7 years

**Description:** - Summarize health care resource utilization among study participants

**Measure:** Summarize health care resource utilization among CLL patients in a real-world setting

**Time Frame:** up to 7 years

#### Secondary Outcomes

**Description:** - Summarize frequencies and percentages of AEs, that led to discontinuation/modification/interruption of therapy or death in CLL patients

**Measure:** Summarize non serious adverse events (AEs) that led to discontinuation/modification/interruption of therapy and all serious adverse events in CLL patients

**Time Frame:** up to 7 years

**Description:** - Summarize HRQoL scores as measured by FACT-G and additional questions from other PRO instruments at baseline and each follow-up

**Measure:** Summarize patient-reported HRQoL scores

**Time Frame:** up to 7 years

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* Age of at least 18 years
* Clinical diagnosis of CLL/SLL that meets published diagnostic criteria (Hallek 2008)
* Initiating anti-CLL/SLL treatment regimen (excluding clinical trials) within ±45 days of enrollment
* Availability of documentation of previous CLL/SLL treatment and duration of response in the patient's medical records if patient has received prior line(s) of treatment (i.e. NOT treatment naïve)
* Willing and able to provide informed consent
* Willing and able to complete PRO instrument
* Willing and able to provide information on patient survey questionnaire
* Willing and able to provide a blood sample at time of enrollment prior to receiving treatment, as possible

Exclusion Criteria:

* Diagnosis of B-cell malignancies other than CLL/SLL
* Estimated life expectancy \<6 months
* Currently receiving treatment in an interventional clinical trial at time of entry into this study \* Note- Exceptions: 1) Patients may enroll in interventional clinical trials for indications other than CLL/SLL, 2) The interventional clinical trial treatment is not the treatment used for meeting Inclusion Criteria #2 (or "Index Treatment"), 3) Patients may enroll in an interventional clinical trial indicated for CLL/SLL as later line of treatment after discontinuing the Index Treatment

**Minimum Age:** 18 Years

**Sampling Method:** NON_PROBABILITY_SAMPLE

**Sex:** ALL

**Standard Ages:**

- ADULT

- OLDER_ADULT

**Study Population:** The registry will aim to enroll approximately 1500 patients with CLL/SLL from a total of 200 sites in the US over a 45 month enrollment period. In order to best capture real-world treatment patterns, site recruitment will aim to include approximately 85% of sites from the community hematology-oncology setting.

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Huntsville

**Country:** United States

**Facility:** Clearview Cancer Institute

**State:** Alabama

**Zip:** 35805

**Location 2:**

**City:** Muscle Shoals

**Country:** United States

**Facility:** Northwest Alabama Cancer Center, PC

**State:** Alabama

**Zip:** 35661

**Location 3:**

**City:** Glendale

**Country:** United States

**Facility:** Arizona Oncology Associates, PC - HAL

**State:** Arizona

**Zip:** 85308

**Location 4:**

**City:** Phoenix

**Country:** United States

**Facility:** Arizona Oncology Associates, PC - HAL

**State:** Arizona

**Zip:** 85016

**Location 5:**

**City:** Phoenix

**Country:** United States

**Facility:** Arizona Oncology Associates, PC - HAL

**State:** Arizona

**Zip:** 85027

**Location 6:**

**City:** Tempe

**Country:** United States

**Facility:** Arizona Oncology Associates, PC - HAL-Scottsdale

**State:** Arizona

**Zip:** 85284

**Location 7:**

**City:** Fort Smith

**Country:** United States

**Facility:** Mercy Research

**State:** Arkansas

**Zip:** 72903

**Location 8:**

**City:** Hot Springs

**Country:** United States

**Facility:** Genesis Cancer Center

**State:** Arkansas

**Zip:** 71913

**Location 9:**

**City:** Jonesboro

**Country:** United States

**Facility:** Clopton Clinic of Jonesboro, Inc.

**State:** Arkansas

**Zip:** 72401

**Location 10:**

**City:** Little Rock

**Country:** United States

**Facility:** CARTI - Central Arkansas Radiation Therapy Institute

**State:** Arkansas

**Zip:** 72205

**Location 11:**

**City:** Concord

**Country:** United States

**Facility:** John Muir Health

**State:** California

**Zip:** 94520

**Location 12:**

**City:** Oceanside

**Country:** United States

**Facility:** North County Oncology Medical Clinic

**State:** California

**Zip:** 92056

**Location 13:**

**City:** Saint Helena

**Country:** United States

**Facility:** Gregory Smith, MD (Private Practice)

**State:** California

**Zip:** 94574

**Location 14:**

**City:** Santa Barbara

**Country:** United States

**Facility:** Sansum Clinic

**State:** California

**Zip:** 93105

**Location 15:**

**City:** Santa Rosa

**Country:** United States

**Facility:** St Joseph Heritage Healthcare

**State:** California

**Zip:** 95403

**Location 16:**

**City:** Solvang

**Country:** United States

**Facility:** Sansum Clinic

**State:** California

**Zip:** 93463

**Location 17:**

**City:** Vallejo

**Country:** United States

**Facility:** Solano Hematology Oncology

**State:** California

**Zip:** 94589

**Location 18:**

**City:** Aurora

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Aurora

**State:** Colorado

**Zip:** 80012

**Location 19:**

**City:** Boulder

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Boulder

**State:** Colorado

**Zip:** 80303

**Location 20:**

**City:** Colorado Springs

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers

**State:** Colorado

**Zip:** 80907

**Location 21:**

**City:** Denver

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP

**State:** Colorado

**Zip:** 80218

**Location 22:**

**City:** Denver

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP

**State:** Colorado

**Zip:** 80220

**Location 23:**

**City:** Lakewood

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Lakewood

**State:** Colorado

**Zip:** 80228

**Location 24:**

**City:** Littleton

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Littleton

**State:** Colorado

**Zip:** 80120-4413

**Location 25:**

**City:** Lone Tree

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Sky Ridge

**State:** Colorado

**Zip:** 80124

**Location 26:**

**City:** Longmont

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Longmont

**State:** Colorado

**Zip:** 80501

**Location 27:**

**City:** Parker

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Parker

**State:** Colorado

**Zip:** 80138

**Location 28:**

**City:** Pueblo

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Pueblo

**State:** Colorado

**Zip:** 81008

**Location 29:**

**City:** Thornton

**Country:** United States

**Facility:** Rocky Mountain Cancer Centers, LLP- Thornton

**State:** Colorado

**Zip:** 80260

**Location 30:**

**City:** Boynton Beach

**Country:** United States

**Facility:** University Cancer Institute, LLC

**State:** Florida

**Zip:** 33426

**Location 31:**

**City:** Fort Lauderdale

**Country:** United States

**Facility:** Broward Oncology Associates, PA

**State:** Florida

**Zip:** 33308

**Location 32:**

**City:** Jacksonville

**Country:** United States

**Facility:** Cancer Specialists, LLC

**State:** Florida

**Zip:** 32082

**Location 33:**

**City:** Jacksonville

**Country:** United States

**Facility:** Baptist MD Anderson Cancer Center

**State:** Florida

**Zip:** 32207

**Location 34:**

**City:** Lakeland

**Country:** United States

**Facility:** Lakeland Regional Health Systems Inc

**State:** Florida

**Zip:** 33805

**Location 35:**

**City:** Lakeland

**Country:** United States

**Facility:** Watson Clinic Cancer and Research Center

**State:** Florida

**Zip:** 33805

**Location 36:**

**City:** Pensacola

**Country:** United States

**Facility:** Sacred Heart Cancer Center

**State:** Florida

**Zip:** 32504

**Location 37:**

**City:** Albany

**Country:** United States

**Facility:** Phoebe Putney Memorial Hospital

**State:** Georgia

**Zip:** 31701

**Location 38:**

**City:** Augusta

**Country:** United States

**Facility:** Georgia Cancer Center at Augusta University

**State:** Georgia

**Zip:** 30912

**Location 39:**

**City:** Brunswick

**Country:** United States

**Facility:** Southeast Georgia Physician Associates Hematology & Oncology

**State:** Georgia

**Zip:** 31520

**Location 40:**

**City:** Chicago

**Country:** United States

**Facility:** The University of Chicago

**State:** Illinois

**Zip:** 60637

**Location 41:**

**City:** Harvey

**Country:** United States

**Facility:** Ingalls Memorial Hospital

**State:** Illinois

**Zip:** 60426

**Location 42:**

**City:** Normal

**Country:** United States

**Facility:** Mid-Illinois Hematology & Oncology Associates,Ltd.

**State:** Illinois

**Zip:** 61761

**Location 43:**

**City:** Peoria

**Country:** United States

**Facility:** Illinois Cancer Care, P.C.

**State:** Illinois

**Zip:** 61615-7828

**Location 44:**

**City:** Rockford

**Country:** United States

**Facility:** OSF Saint Anthony Medical Center

**State:** Illinois

**Zip:** 61108

**Location 45:**

**City:** Skokie

**Country:** United States

**Facility:** Orchard Healthcare Research Inc.

**State:** Illinois

**Zip:** 60077

**Location 46:**

**City:** Tinley Park

**Country:** United States

**Facility:** Healthcare Research Network III, LLC

**State:** Illinois

**Zip:** 60487

**Location 47:**

**City:** Anderson

**Country:** United States

**Facility:** St. Vincent Anderson Regional Hospital

**State:** Indiana

**Zip:** 46016

**Location 48:**

**City:** Indianapolis

**Country:** United States

**Facility:** Community Health Network

**State:** Indiana

**Zip:** 46219

**Location 49:**

**City:** Indianapolis

**Country:** United States

**Facility:** Investigative Clinical Research of Indiana, LLC

**State:** Indiana

**Zip:** 46260

**Location 50:**

**City:** Lafayette

**Country:** United States

**Facility:** Horizon Oncology Research, Inc

**State:** Indiana

**Zip:** 47905

**Location 51:**

**City:** South Bend

**Country:** United States

**Facility:** Memorial Medical Group Clinical Research Institute

**State:** Indiana

**Zip:** 46601

**Location 52:**

**City:** Vincennes

**Country:** United States

**Facility:** Good Samaritan Hospital

**State:** Indiana

**Zip:** 47591

**Location 53:**

**City:** Ames

**Country:** United States

**Facility:** McFarland Clinic, P.C.

**State:** Iowa

**Zip:** 50010-3014

**Location 54:**

**City:** Cedar Rapids

**Country:** United States

**Facility:** Physicians Clinic of Iowa

**State:** Iowa

**Zip:** 52402

**Location 55:**

**City:** Waterloo

**Country:** United States

**Facility:** Covenant Clinic

**State:** Iowa

**Zip:** 50702

**Location 56:**

**City:** Topeka

**Country:** United States

**Facility:** Cotton-O'Neil Clinical Research Center, Hematology and Oncology

**State:** Kansas

**Zip:** 66606

**Location 57:**

**City:** Mount Sterling

**Country:** United States

**Facility:** Montgomery Cancer Center

**State:** Kentucky

**Zip:** 40353

**Location 58:**

**City:** Paducah

**Country:** United States

**Facility:** West Ky Hematology & Oncology Group, PSC

**State:** Kentucky

**Zip:** 42003

**Location 59:**

**City:** Covington

**Country:** United States

**Facility:** Pontchartrain Cancer Center

**State:** Louisiana

**Zip:** 70433

**Location 60:**

**City:** New Orleans

**Country:** United States

**Facility:** Tulane University

**State:** Louisiana

**Zip:** 70112

**Location 61:**

**City:** Shreveport

**Country:** United States

**Facility:** Willis-Knighton Cancer Center

**State:** Louisiana

**Zip:** 71103

**Location 62:**

**City:** Shreveport

**Country:** United States

**Facility:** Christus Cancer Treatment Center

**State:** Louisiana

**Zip:** 71105

**Location 63:**

**City:** Lewiston

**Country:** United States

**Facility:** Maine Research Associates

**State:** Maine

**Zip:** 04240

**Location 64:**

**City:** Rockport

**Country:** United States

**Facility:** Penobscot Bay Medical Center

**State:** Maine

**Zip:** 04856

**Location 65:**

**City:** Scarborough

**Country:** United States

**Facility:** Maine Center for Cancer Medicine

**State:** Maine

**Zip:** 04074

**Location 66:**

**City:** Cumberland

**Country:** United States

**Facility:** Western Maryland Health System

**State:** Maryland

**Zip:** 21502

**Location 67:**

**City:** Hagerstown

**Country:** United States

**Facility:** Antietam Oncology and Hematology Group PC

**State:** Maryland

**Zip:** 21740

**Location 68:**

**City:** Pittsfield

**Country:** United States

**Facility:** Berkshire Hematology Oncology, PC

**State:** Massachusetts

**Zip:** 01201

**Location 69:**

**City:** Plymouth

**Country:** United States

**Facility:** Beth Israel Deaconess Hospital- Plymouth

**State:** Massachusetts

**Zip:** 02360

**Location 70:**

**City:** Kalamazoo

**Country:** United States

**Facility:** West Michigan Cancer Center

**State:** Michigan

**Zip:** 49007

**Location 71:**

**City:** Novi

**Country:** United States

**Facility:** St John Providence Hospital

**State:** Michigan

**Zip:** 48374-1233

**Location 72:**

**City:** Saint Cloud

**Country:** United States

**Facility:** Coborn Cancer Center

**State:** Minnesota

**Zip:** 56303

**Location 73:**

**City:** Jackson

**Country:** United States

**Facility:** Jackson Oncology Associates

**State:** Mississippi

**Zip:** 39202

**Location 74:**

**City:** Bolivar

**Country:** United States

**Facility:** Central Cancer Care Center

**State:** Missouri

**Zip:** 65613

**Location 75:**

**City:** Jefferson City

**Country:** United States

**Facility:** Jefferson City Medical Group

**State:** Missouri

**Zip:** 65109

**Location 76:**

**City:** Saint Joseph

**Country:** United States

**Facility:** Heartland Regional Medical Center d/b/a Cancer Care St. Joseph Mosaic Life Care

**State:** Missouri

**Zip:** 64506

**Location 77:**

**City:** Billings

**Country:** United States

**Facility:** St. Vincent Frontier Cancer Center

**State:** Montana

**Zip:** 59102

**Location 78:**

**City:** Hastings

**Country:** United States

**Facility:** Mary Lanning Healthcare Morrison Cancer Center

**State:** Nebraska

**Zip:** 68901

**Location 79:**

**City:** Lincoln

**Country:** United States

**Facility:** Nebraska Hematology-Oncology, P.C

**State:** Nebraska

**Zip:** 68506

**Location 80:**

**City:** Lincoln

**Country:** United States

**Facility:** Southeast Nebraska Cancer Center

**State:** Nebraska

**Zip:** 68510

**Location 81:**

**City:** Omaha

**Country:** United States

**Facility:** Cancer Alliance of Nebraska

**State:** Nebraska

**Zip:** 68106

**Location 82:**

**City:** Elizabeth

**Country:** United States

**Facility:** Trinitas Hospital

**State:** New Jersey

**Zip:** 07207

**Location 83:**

**City:** Englewood

**Country:** United States

**Facility:** Hematology Oncology Physicians of Englewood, PA

**State:** New Jersey

**Zip:** 07631

**Location 84:**

**City:** Neptune

**Country:** United States

**Facility:** Meridian Health Systems

**State:** New Jersey

**Zip:** 07753

**Location 85:**

**City:** New Brunswick

**Country:** United States

**Facility:** Saint Peter's University Hospital

**State:** New Jersey

**Zip:** 08901

**Location 86:**

**City:** Paramus

**Country:** United States

**Facility:** The Valley Hospital

**State:** New Jersey

**Zip:** 07652

**Location 87:**

**City:** Williamstown

**Country:** United States

**Facility:** Southern Oncology Hematology Associates

**State:** New Jersey

**Zip:** 08360

**Location 88:**

**City:** Farmington

**Country:** United States

**Facility:** San Juan Oncology Associates

**State:** New Mexico

**Zip:** 87401

**Location 89:**

**City:** Bronx

**Country:** United States

**Facility:** Eastchester Center for Cancer Care

**State:** New York

**Zip:** 10469

**Location 90:**

**City:** East Hills

**Country:** United States

**Facility:** St. Francis Hospital

**State:** New York

**Zip:** 11548

**Location 91:**

**City:** East Setauket

**Country:** United States

**Facility:** North Shore Hematology Oncology Associates, PC

**State:** New York

**Zip:** 11733

**Location 92:**

**City:** East Syracuse

**Country:** United States

**Facility:** Hematology Oncology Associates Of Central New York

**State:** New York

**Zip:** 13057

**Location 93:**

**City:** Glens Falls

**Country:** United States

**Facility:** Glen Falls Hospital Cancer Center

**State:** New York

**Zip:** 12801

**Location 94:**

**City:** Manhasset

**Country:** United States

**Facility:** North Shore Long Island Jewish Hospital

**State:** New York

**Zip:** 11030

**Location 95:**

**City:** Mount Kisco

**Country:** United States

**Facility:** Northern Westchester Hospital

**State:** New York

**Zip:** 10549

**Location 96:**

**City:** New York

**Country:** United States

**Facility:** MHO Research Foundation, Inc.

**State:** New York

**Zip:** 10016

**Location 97:**

**City:** Nyack

**Country:** United States

**Facility:** Hematology Oncology Associates of Rockland

**State:** New York

**Zip:** 10960

**Location 98:**

**City:** Syracuse

**Country:** United States

**Facility:** SUNY Upstate Medical Center

**State:** New York

**Zip:** 13210

**Location 99:**

**City:** White Plains

**Country:** United States

**Facility:** White Plains Hospital

**State:** New York

**Zip:** 10601

**Location 100:**

**City:** Williamsville

**Country:** United States

**Facility:** CCS Oncology

**State:** New York

**Zip:** 14221

**Location 101:**

**City:** Cary

**Country:** United States

**Facility:** Waverly Hematology Oncology

**State:** North Carolina

**Zip:** 27518

**Location 102:**

**City:** Charlotte

**Country:** United States

**Facility:** Levine Cancer Institute

**State:** North Carolina

**Zip:** 28204

**Location 103:**

**City:** Greenville

**Country:** United States

**Facility:** Leo Jenkins Cancer Center/ECU School of Medicine

**State:** North Carolina

**Zip:** 27834

**Location 104:**

**City:** Morehead City

**Country:** United States

**Facility:** Raab Clinic

**State:** North Carolina

**Zip:** 28557

**Location 105:**

**City:** Cleveland

**Country:** United States

**Facility:** Cleveland Clinic

**State:** Ohio

**Zip:** 44195

**Location 106:**

**City:** Columbus

**Country:** United States

**Facility:** Mid Ohio Oncology Hematology, DBA The Mark H. Zangmeister Center

**State:** Ohio

**Zip:** 43219

**Location 107:**

**City:** Middletown

**Country:** United States

**Facility:** Wright State University

**State:** Ohio

**Zip:** 45005

**Location 108:**

**City:** Toledo

**Country:** United States

**Facility:** Toledo Community Hospital Oncology Program - CCOP Toledo

**State:** Ohio

**Zip:** 43623

**Location 109:**

**City:** Youngstown

**Country:** United States

**Facility:** St. Elizabeth Hospital

**State:** Ohio

**Zip:** 44501

**Location 110:**

**City:** Oklahoma City

**Country:** United States

**Facility:** Mercy Research - Mercy Clinic Oncology and Hematology

**State:** Oklahoma

**Zip:** 73120

**Location 111:**

**City:** Eugene

**Country:** United States

**Facility:** Willamette Valley Cancer Institute and Research Center

**State:** Oregon

**Zip:** 97401

**Location 112:**

**City:** Medford

**Country:** United States

**Facility:** Hematology Oncology Associates, PC

**State:** Oregon

**Zip:** 97504

**Location 113:**

**City:** Medford

**Country:** United States

**Facility:** Hematology Oncology Associates

**State:** Oregon

**Zip:** 97504

**Location 114:**

**City:** Portland

**Country:** United States

**Facility:** Compass Oncology- Hoyt

**State:** Oregon

**Zip:** 97213-2982

**Location 115:**

**City:** Portland

**Country:** United States

**Facility:** Compass Oncology- Barnes

**State:** Oregon

**Zip:** 97225

**Location 116:**

**City:** Portland

**Country:** United States

**Facility:** Compass Oncology- Broadway

**State:** Oregon

**Zip:** 97227

**Location 117:**

**City:** Springfield

**Country:** United States

**Facility:** Willamette Valley Cancer Institute and Research Center

**State:** Oregon

**Zip:** 97477

**Location 118:**

**City:** Tualatin

**Country:** United States

**Facility:** Compass Oncology- Tualatin

**State:** Oregon

**Zip:** 97062

**Location 119:**

**City:** Lancaster

**Country:** United States

**Facility:** Lancaster Cancer Center

**State:** Pennsylvania

**Zip:** 17605

**Location 120:**

**City:** Monroeville

**Country:** United States

**Facility:** University Cancer Institute, LLC

**State:** Pennsylvania

**Zip:** 15232

**Location 121:**

**City:** Philadelphia

**Country:** United States

**Facility:** Einstein Medical Center

**State:** Pennsylvania

**Zip:** 19141

**Location 122:**

**City:** Scranton

**Country:** United States

**Facility:** Hematology & Oncology Associates of Northeastern PA

**State:** Pennsylvania

**Zip:** 18510

**Location 123:**

**City:** Williamsport

**Country:** United States

**Facility:** Susquehanna Cancer Center

**State:** Pennsylvania

**Zip:** 17701

**Location 124:**

**City:** York

**Country:** United States

**Facility:** Cancer Care Associates of York

**State:** Pennsylvania

**Zip:** 17403

**Location 125:**

**City:** Charleston

**Country:** United States

**Facility:** Charleston Cancer Center

**State:** South Carolina

**Zip:** 29406

**Location 126:**

**City:** Easley

**Country:** United States

**Facility:** Cancer Centers of the Carolinas- Easley

**State:** South Carolina

**Zip:** 29640

**Location 127:**

**City:** Greenville

**Country:** United States

**Facility:** Cancer Centers of the Carolinas- Butternut

**State:** South Carolina

**Zip:** 29605

**Location 128:**

**City:** Greenville

**Country:** United States

**Facility:** Hematology and Oncology Associates of SC, LLC

**State:** South Carolina

**Zip:** 29605

**Location 129:**

**City:** Greenville

**Country:** United States

**Facility:** Greenville Hospital System Medical Center

**State:** South Carolina

**Zip:** 29615

**Location 130:**

**City:** Greer

**Country:** United States

**Facility:** Greenville Health System

**State:** South Carolina

**Zip:** 29650

**Location 131:**

**City:** Hilton Head Island

**Country:** United States

**Facility:** South Carolina Cancer Specialists

**State:** South Carolina

**Zip:** 29926

**Location 132:**

**City:** Rock Hill

**Country:** United States

**Facility:** Carolina Blood and Cancer Care Associates

**State:** South Carolina

**Zip:** 29732

**Location 133:**

**City:** Seneca

**Country:** United States

**Facility:** Cancer Centers of the Carolinas - Seneca

**State:** South Carolina

**Zip:** 29672

**Location 134:**

**City:** Spartanburg

**Country:** United States

**Facility:** Spartanburg Regional Healthcare System

**State:** South Carolina

**Zip:** 29303

**Location 135:**

**City:** Spartanburg

**Country:** United States

**Facility:** Cancer Centers of the Carolinas- Spartanburg

**State:** South Carolina

**Zip:** 29307

**Location 136:**

**City:** Watertown

**Country:** United States

**Facility:** Prairie Lakes Hospital

**State:** South Dakota

**Zip:** 57201

**Location 137:**

**City:** Cookeville

**Country:** United States

**Facility:** Cookeville Regional Medical Center

**State:** Tennessee

**Zip:** 38501

**Location 138:**

**City:** Jackson

**Country:** United States

**Facility:** Jackson Madison County General Hospital

**State:** Tennessee

**Zip:** 38301

**Location 139:**

**City:** Nashville

**Country:** United States

**Facility:** Meharry Medical College

**State:** Tennessee

**Zip:** 37208

**Location 140:**

**City:** Nashville

**Country:** United States

**Facility:** Vanderbilt University Medical Center

**State:** Tennessee

**Zip:** 37232

**Location 141:**

**City:** Abilene

**Country:** United States

**Facility:** Hendrick Cancer Center

**State:** Texas

**Zip:** 79601

**Location 142:**

**City:** Abilene

**Country:** United States

**Facility:** Texas Oncology - Abilene

**State:** Texas

**Zip:** 79606-5208

**Location 143:**

**City:** Allen

**Country:** United States

**Facility:** Texas Oncology- Allen

**State:** Texas

**Zip:** 75013

**Location 144:**

**City:** Amarillo

**Country:** United States

**Facility:** Texas Oncology - Amarillo

**State:** Texas

**Zip:** 79106

**Location 145:**

**City:** Arlington

**Country:** United States

**Facility:** Texas Oncoogy - Arlington North

**State:** Texas

**Zip:** 76012

**Location 146:**

**City:** Arlington

**Country:** United States

**Facility:** Texas Oncology- Arlington South

**State:** Texas

**Zip:** 76014

**Location 147:**

**City:** Austin

**Country:** United States

**Facility:** Texas Oncology - Austin Midtown

**State:** Texas

**Zip:** 78705

**Location 148:**

**City:** Austin

**Country:** United States

**Facility:** Texas Oncology - P.A.- Austin

**State:** Texas

**Zip:** 78731

**Location 149:**

**City:** Austin

**Country:** United States

**Facility:** South Austin Cancer Center

**State:** Texas

**Zip:** 78745

**Location 150:**

**City:** Beaumont

**Country:** United States

**Facility:** Texas Oncology - PA

**State:** Texas

**Zip:** 77701

**Location 151:**

**City:** Beaumont

**Country:** United States

**Facility:** Texas Oncology, P.A - Beaumont

**State:** Texas

**Zip:** 77702

**Location 152:**

**City:** Bedford

**Country:** United States

**Facility:** Texas Oncology-Bedford

**State:** Texas

**Zip:** 76022

**Location 153:**

**City:** Carrollton

**Country:** United States

**Facility:** Texas Oncology - Carrollton

**State:** Texas

**Zip:** 75010

**Location 154:**

**City:** Dallas

**Country:** United States

**Facility:** Texas Oncology - Dallas Presbyterian

**State:** Texas

**Zip:** 75231

**Location 155:**

**City:** Dallas

**Country:** United States

**Facility:** Baylor Charles A. Sammons Cancer Center

**State:** Texas

**Zip:** 75246

**Location 156:**

**City:** El Paso

**Country:** United States

**Facility:** El Paso Cancer Treatment Center- West

**State:** Texas

**Zip:** 79902

**Location 157:**

**City:** El Paso

**Country:** United States

**Facility:** Texas Oncology - P.A. - El Paso

**State:** Texas

**Zip:** 79915

**Location 158:**

**City:** El Paso

**Country:** United States

**Facility:** Texas Oncology - El Paso

**State:** Texas

**Zip:** 79939

**Location 159:**

**City:** Flower Mound

**Country:** United States

**Facility:** Texas Oncology, P.A.- Flower Mound

**State:** Texas

**Zip:** 75028

**Location 160:**

**City:** Grapevine

**Country:** United States

**Facility:** Texas Oncology-Grapevine

**State:** Texas

**Zip:** 76051

**Location 161:**

**City:** Harlingen

**Country:** United States

**Facility:** Texas Oncology PA

**State:** Texas

**Zip:** 78550

**Location 162:**

**City:** Longview

**Country:** United States

**Facility:** Texas Oncology - P.A.- Longview

**State:** Texas

**Zip:** 75601

**Location 163:**

**City:** McAllen

**Country:** United States

**Facility:** Texas Oncology - P.A.-McAllen

**State:** Texas

**Zip:** 78503

**Location 164:**

**City:** McKinney

**Country:** United States

**Facility:** Texas Oncology- McKinney

**State:** Texas

**Zip:** 75071

**Location 165:**

**City:** Mesquite

**Country:** United States

**Facility:** Texas Oncology -P.A.- Mesquite

**State:** Texas

**Zip:** 75150

**Location 166:**

**City:** Midland

**Country:** United States

**Facility:** Texas Oncology - P.A.- Midland

**State:** Texas

**Zip:** 79701

**Location 167:**

**City:** Odessa

**Country:** United States

**Facility:** Texas Oncology - P.A.- Odessa

**State:** Texas

**Zip:** 79761

**Location 168:**

**City:** Paris

**Country:** United States

**Facility:** Texas Oncology - P.A.- Paris

**State:** Texas

**Zip:** 75460-5004

**Location 169:**

**City:** Plano

**Country:** United States

**Facility:** Texas Oncology - P.A.- Plano

**State:** Texas

**Zip:** 75075-7787

**Location 170:**

**City:** Plano

**Country:** United States

**Facility:** Texas Oncology- Plano West

**State:** Texas

**Zip:** 75093

**Location 171:**

**City:** Rockwall

**Country:** United States

**Facility:** Texas Oncology - Rockwall

**State:** Texas

**Zip:** 75032

**Location 172:**

**City:** San Antonio

**Country:** United States

**Facility:** Texas Oncology- San Antonio Downtown

**State:** Texas

**Zip:** 78212

**Location 173:**

**City:** San Antonio

**Country:** United States

**Facility:** Texas Oncology- San Antonio Northeast

**State:** Texas

**Zip:** 78217

**Location 174:**

**City:** San Antonio

**Country:** United States

**Facility:** Texas Oncology- San Antonio Stone Oak

**State:** Texas

**Zip:** 78258

**Location 175:**

**City:** Sherman

**Country:** United States

**Facility:** Texas Oncology - P.A.-Sherman

**State:** Texas

**Zip:** 75090

**Location 176:**

**City:** Sugar Land

**Country:** United States

**Facility:** Texas Oncology - P.A.-Sugar Land

**State:** Texas

**Zip:** 77479

**Location 177:**

**City:** Tyler

**Country:** United States

**Facility:** Tyler Hematology Oncology

**State:** Texas

**Zip:** 75701

**Location 178:**

**City:** Tyler

**Country:** United States

**Facility:** Texas Oncology-P.A-Tyler

**State:** Texas

**Zip:** 75702

**Location 179:**

**City:** Waco

**Country:** United States

**Facility:** Texas Oncology, P.A. - Horizon Circle

**State:** Texas

**Zip:** 76712

**Location 180:**

**City:** Waco

**Country:** United States

**Facility:** Texas Oncology, P.A. - Waco

**State:** Texas

**Zip:** 76712

**Location 181:**

**City:** Webster

**Country:** United States

**Facility:** Texas Oncology-P.A.- Webster

**State:** Texas

**Zip:** 77598-4420

**Location 182:**

**City:** Weslaco

**Country:** United States

**Facility:** Texas Oncology-Weslaco

**State:** Texas

**Zip:** 78596

**Location 183:**

**City:** Newport News

**Country:** United States

**Facility:** Cancer Specialists of Tidewater

**State:** Virginia

**Zip:** 23601

**Location 184:**

**City:** Winchester

**Country:** United States

**Facility:** Shenandoah Oncology, P.C.

**State:** Virginia

**Zip:** 22601

**Location 185:**

**City:** Everett

**Country:** United States

**Facility:** Providence Everett Medical Center

**State:** Washington

**Zip:** 98201

**Location 186:**

**City:** Seattle

**Country:** United States

**Facility:** Swedish Cancer Institute

**State:** Washington

**Zip:** 98104

**Location 187:**

**City:** Tacoma

**Country:** United States

**Facility:** Multicare Institute for Research and Innovation

**State:** Washington

**Zip:** 98405

**Location 188:**

**City:** Vancouver

**Country:** United States

**Facility:** Compass oncology

**State:** Washington

**Zip:** 98684

**Location 189:**

**City:** Walla Walla

**Country:** United States

**Facility:** Providence St. Mary Regional Cancer Center

**State:** Washington

**Zip:** 99362

**Location 190:**

**City:** Yakima

**Country:** United States

**Facility:** Yakima Valley Memorial Hospital/North Star Lodge

**State:** Washington

**Zip:** 98902

**Location 191:**

**City:** Green Bay

**Country:** United States

**Facility:** HSHS St. Vincent Hospital Regional Cancer Center

**State:** Wisconsin

**Zip:** 54301

**Location 192:**

**City:** Waukesha

**Country:** United States

**Facility:** ProHealth Care

**State:** Wisconsin

**Zip:** 53188

#### Overall Officials

**Official 1:**

**Affiliation:** Pharmacyclics LLC.

**Name:** Alex Young

**Role:** STUDY_DIRECTOR

### References Module

#### References

**Citation:** Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Dohner H, Hillmen P, Keating MJ, Montserrat E, Rai KR, Kipps TJ; International Workshop on Chronic Lymphocytic Leukemia. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood. 2008 Jun 15;111(12):5446-56. doi: 10.1182/blood-2007-06-093906. Epub 2008 Jan 23. Erratum In: Blood. 2008 Dec 15;112(13):5259.

**PMID:** 18216293

#### See Also Links

**Label:** clinical study report synopsis

**URL:** https://www.abbvieclinicaltrials.com/study/?id=PCYC-1134M-CA&Latitude=&Longitude=&LocationName=#additional-resources-section

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000009370

- Term: Neoplasms by Histologic Type

- ID: D000009369

- Term: Neoplasms

- ID: D000006402

- Term: Hematologic Diseases

- ID: D000008232

- Term: Lymphoproliferative Disorders

- ID: D000008206

- Term: Lymphatic Diseases

- ID: D000007160

- Term: Immunoproliferative Disorders

- ID: D000007154

- Term: Immune System Diseases

- ID: D000015448

- Term: Leukemia, B-Cell

- ID: D000002908

- Term: Chronic Disease

- ID: D000020969

- Term: Disease Attributes

- ID: D000010335

- Term: Pathologic Processes

### Condition Browse Module - Browse Branches

- Abbrev: BC04

- Name: Neoplasms

- Abbrev: BC15

- Name: Blood and Lymph Conditions

- Abbrev: All

- Name: All Conditions

- Abbrev: BC20

- Name: Immune System Diseases

- Abbrev: BC23

- Name: Symptoms and General Pathology

- Abbrev: Rare

- Name: Rare Diseases

### Condition Browse Module - Browse Leaves

- ID: M10945

- Name: Leukemia

- Relevance: HIGH

- As Found: Leukemia

- ID: M10951

- Name: Leukemia, Lymphoid

- Relevance: HIGH

- As Found: Lymphocytic Leukemia

- ID: M18116

- Name: Leukemia, Lymphocytic, Chronic, B-Cell

- Relevance: HIGH

- As Found: Chronic Lymphocytic Leukemia

- ID: M12315

- Name: Neoplasms by Histologic Type

- Relevance: LOW

- As Found: Unknown

- ID: M9490

- Name: Hematologic Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M11225

- Name: Lymphoproliferative Disorders

- Relevance: LOW

- As Found: Unknown

- ID: M11203

- Name: Lymphatic Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M10206

- Name: Immunoproliferative Disorders

- Relevance: LOW

- As Found: Unknown

- ID: M10200

- Name: Immune System Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M18115

- Name: Leukemia, B-Cell

- Relevance: LOW

- As Found: Unknown

- ID: M6147

- Name: Chronic Disease

- Relevance: LOW

- As Found: Unknown

- ID: M22700

- Name: Disease Attributes

- Relevance: LOW

- As Found: Unknown

- ID: T1308

- Name: Chronic Lymphocytic Leukemia

- Relevance: HIGH

- As Found: Chronic Lymphocytic Leukemia

- ID: T1303

- Name: Chronic Graft Versus Host Disease

- Relevance: HIGH

- As Found: Chronic

### Condition Browse Module - Meshes

- ID: D000007938

- Term: Leukemia

- ID: D000007945

- Term: Leukemia, Lymphoid

- ID: D000015451

- Term: Leukemia, Lymphocytic, Chronic, B-Cell

### Misc Info Module

- Version Holder: 2024-05-24
