## Protocol Section
### Identification Module
**NCT ID:** NCT00898079

**Brief Title:** Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

**Official Title:** A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors

**NCT ID Aliases:**
- NCT00228735
#### Organization Study ID Info
**ID:** ABTR01B1
#### Organization
**Class:** NETWORK
**Full Name:** Children's Oncology Group
#### Secondary ID Infos
**Domain:** CTRP (Clinical Trial Reporting Program)
**ID:** NCI-2009-00324
**Type:** REGISTRY
**ID:** CDR0000271415
**ID:** COG-ABTR01B1
**Domain:** Childrens Oncology Group
**ID:** ABTR01B1
**Type:** OTHER
**Domain:** CTEP
**ID:** ABTR01B1
**Type:** OTHER
**ID:** U10CA098543
**Link:** https://reporter.nih.gov/quickSearch/U10CA098543
**Type:** NIH
**ID:** UG1CA189958
**Link:** https://reporter.nih.gov/quickSearch/UG1CA189958
**Type:** NIH
### Status Module
#### Completion Date
**Date:** 2018-06-30

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2018-07-19

**Type:** ACTUAL

**Last Update Submit Date:** 2018-07-17

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2018-06-30

**Type:** ACTUAL

#### Start Date
**Date:** 2003-10-13

**Type:** ACTUAL

**Status Verified Date:** 2018-07

#### Study First Post Date
**Date:** 2009-05-12
**Type:** ESTIMATED
**Study First Submit Date:** 2009-05-09
**Study First Submit QC Date:** 2009-05-09
### Sponsor Collaborators Module

#### Collaborators

**Class:** NIH

**Name:** National Cancer Institute (NCI)

#### Lead Sponsor

**Class:** NETWORK

**Name:** Children's Oncology Group

#### Responsible Party

**Type:** SPONSOR

### Description Module

**Brief Summary:** This study is collecting and storing malignant, borderline malignant neoplasms, and related biological samples from young patients with cancer. Collecting and storing samples of tumor tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help the study of cancer in the future.

**Detailed Description:** OBJECTIVES:

I. Collect malignant, borderline malignant neoplasms, and related biological specimens from Children's Oncology Group institutions for cases in which there is no disease-specific biologic protocol.

II. Provide a repository for long-term storage of malignant, borderline malignant neoplasms, and related biological specimens from these patients.

III. Make specimens available to qualified researchers to understand the biology of cancer in these patients.

OUTLINE:

Tumor tissue samples, blood, and bone marrow aspirates are collected and stored for future analysis.

### Conditions Module

**Conditions:**

- Acute Undifferentiated Leukemia

- Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative

- Childhood Acute Lymphoblastic Leukemia

- Childhood Acute Myeloid Leukemia

- Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive

- Childhood Solid Neoplasm

- Chronic Lymphocytic Leukemia

- Hairy Cell Leukemia

- Juvenile Myelomonocytic Leukemia

- Mast Cell Leukemia

- Neoplasm of Uncertain Malignant Potential

- Prolymphocytic Leukemia

- Secondary Acute Myeloid Leukemia

- T-Cell Large Granular Lymphocyte Leukemia

### Design Module

#### Enrollment Info

**Count:** 2545

**Type:** ACTUAL

**Study Type:** OBSERVATIONAL

### Arms Interventions Module

#### Arm Group 1

**Description:** Tumor tissue samples, blood, and bone marrow aspirates are collected and stored for future analysis.

**Intervention Names:**

- Other: Cytology Specimen Collection Procedure

**Label:** Observational

### Interventions

#### Intervention 1

**Arm Group Labels:**

- Observational

**Description:** Correlative studies

**Name:** Cytology Specimen Collection Procedure

**Other Names:**

- Cytologic Sampling

**Type:** OTHER

### Outcomes Module

#### Primary Outcomes

**Measure:** Repository of malignant, borderline malignant neoplasms, and related biological specimens

**Time Frame:** Baseline

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* Meets any of the following criteria:

  * Diagnosed with primary neoplasm
  * Developed a second malignant neoplasm
  * Any diagnoses having an ICD-O Morphology Code ending in 1, 2, or 3 as listed in the International Classification of Disease for Oncology, Third Edition
* Must have biological specimens including solid tumors and leukemias available

  * Solid tumors meeting the following criteria:

    * Snap frozen primary tumor OR OCT embedded primary tumor OR formalin fixed (block or tissue in formalin) primary tumor AND at least 10 unstained paraffin slides for NIH Mandated QC (tumors that have undergone central pathology review are allowed)

      * Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
  * Pleural fluid or cytologic specimens meeting the following criteria:

    * At least 1 mL of fluid and at least 2 unstained cytospin slides (or 2 unstained smears)

      * Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
  * ALL/AML

    * 3-6 mL of bone marrow aspirate and 10 mL of whole blood
* Not eligible for disease-specific biology or banking protocol

**Maximum Age:** 30 Years

**Sampling Method:** NON_PROBABILITY_SAMPLE

**Sex:** ALL

**Standard Ages:**

- CHILD

- ADULT

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Birmingham

**Country:** United States

**Facility:** Children's Hospital of Alabama

**State:** Alabama

**Zip:** 35233

**Location 2:**

**City:** Birmingham

**Country:** United States

**Facility:** University of Alabama at Birmingham Cancer Center

**State:** Alabama

**Zip:** 35233

**Location 3:**

**City:** Phoenix

**Country:** United States

**Facility:** Phoenix Childrens Hospital

**State:** Arizona

**Zip:** 85016

**Location 4:**

**City:** Little Rock

**Country:** United States

**Facility:** Arkansas Children's Hospital

**State:** Arkansas

**Zip:** 72202-3591

**Location 5:**

**City:** Little Rock

**Country:** United States

**Facility:** University of Arkansas for Medical Sciences

**State:** Arkansas

**Zip:** 72205

**Location 6:**

**City:** Downey

**Country:** United States

**Facility:** Kaiser Permanente Downey Medical Center

**State:** California

**Zip:** 90242

**Location 7:**

**City:** Duarte

**Country:** United States

**Facility:** City of Hope Comprehensive Cancer Center

**State:** California

**Zip:** 91010

**Location 8:**

**City:** Loma Linda

**Country:** United States

**Facility:** Loma Linda University Medical Center

**State:** California

**Zip:** 92354

**Location 9:**

**City:** Long Beach

**Country:** United States

**Facility:** Miller Children's and Women's Hospital Long Beach

**State:** California

**Zip:** 90806

**Location 10:**

**City:** Los Angeles

**Country:** United States

**Facility:** Children's Hospital Los Angeles

**State:** California

**Zip:** 90027

**Location 11:**

**City:** Los Angeles

**Country:** United States

**Facility:** Cedars Sinai Medical Center

**State:** California

**Zip:** 90048

**Location 12:**

**City:** Los Angeles

**Country:** United States

**Facility:** Mattel Children's Hospital UCLA

**State:** California

**Zip:** 90095

**Location 13:**

**City:** Los Angeles

**Country:** United States

**Facility:** UCLA / Jonsson Comprehensive Cancer Center

**State:** California

**Zip:** 90095

**Location 14:**

**City:** Madera

**Country:** United States

**Facility:** Children's Hospital Central California

**State:** California

**Zip:** 93636-8762

**Location 15:**

**City:** Oakland

**Country:** United States

**Facility:** Children's Hospital and Research Center at Oakland

**State:** California

**Zip:** 94609-1809

**Location 16:**

**City:** Oakland

**Country:** United States

**Facility:** Kaiser Permanente-Oakland

**State:** California

**Zip:** 94611

**Location 17:**

**City:** Orange

**Country:** United States

**Facility:** Children's Hospital of Orange County

**State:** California

**Zip:** 92868

**Location 18:**

**City:** Palo Alto

**Country:** United States

**Facility:** Lucile Packard Children's Hospital Stanford University

**State:** California

**Zip:** 94304

**Location 19:**

**City:** San Diego

**Country:** United States

**Facility:** Rady Children's Hospital - San Diego

**State:** California

**Zip:** 92123

**Location 20:**

**City:** San Francisco

**Country:** United States

**Facility:** UCSF Medical Center-Parnassus

**State:** California

**Zip:** 94143

**Location 21:**

**City:** San Francisco

**Country:** United States

**Facility:** UCSF Medical Center-Mission Bay

**State:** California

**Zip:** 94158

**Location 22:**

**City:** Aurora

**Country:** United States

**Facility:** Children's Hospital Colorado

**State:** Colorado

**Zip:** 80045

**Location 23:**

**City:** Denver

**Country:** United States

**Facility:** Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center

**State:** Colorado

**Zip:** 80218

**Location 24:**

**City:** Hartford

**Country:** United States

**Facility:** Connecticut Children's Medical Center

**State:** Connecticut

**Zip:** 06106

**Location 25:**

**City:** Wilmington

**Country:** United States

**Facility:** Alfred I duPont Hospital for Children

**State:** Delaware

**Zip:** 19803

**Location 26:**

**City:** Washington

**Country:** United States

**Facility:** MedStar Georgetown University Hospital

**State:** District of Columbia

**Zip:** 20007

**Location 27:**

**City:** Washington

**Country:** United States

**Facility:** Children's National Medical Center

**State:** District of Columbia

**Zip:** 20010

**Location 28:**

**City:** Fort Lauderdale

**Country:** United States

**Facility:** Broward Health Medical Center

**State:** Florida

**Zip:** 33316

**Location 29:**

**City:** Fort Myers

**Country:** United States

**Facility:** Lee Memorial Health System

**State:** Florida

**Zip:** 33901

**Location 30:**

**City:** Fort Myers

**Country:** United States

**Facility:** Golisano Children's Hospital of Southwest Florida

**State:** Florida

**Zip:** 33908

**Location 31:**

**City:** Gainesville

**Country:** United States

**Facility:** University of Florida Health Science Center - Gainesville

**State:** Florida

**Zip:** 32610

**Location 32:**

**City:** Hollywood

**Country:** United States

**Facility:** Memorial Regional Hospital/Joe DiMaggio Children's Hospital

**State:** Florida

**Zip:** 33021

**Location 33:**

**City:** Jacksonville

**Country:** United States

**Facility:** Nemours Children's Clinic-Jacksonville

**State:** Florida

**Zip:** 32207

**Location 34:**

**City:** Miami

**Country:** United States

**Facility:** University of Miami Miller School of Medicine-Sylvester Cancer Center

**State:** Florida

**Zip:** 33136

**Location 35:**

**City:** Miami

**Country:** United States

**Facility:** Nicklaus Children's Hospital

**State:** Florida

**Zip:** 33155

**Location 36:**

**City:** Miami

**Country:** United States

**Facility:** Miami Cancer Institute

**State:** Florida

**Zip:** 33176

**Location 37:**

**City:** Orlando

**Country:** United States

**Facility:** Florida Hospital Orlando

**State:** Florida

**Zip:** 32803

**Location 38:**

**City:** Orlando

**Country:** United States

**Facility:** Nemours Children's Clinic - Orlando

**State:** Florida

**Zip:** 32806

**Location 39:**

**City:** Orlando

**Country:** United States

**Facility:** Nemours Children's Hospital

**State:** Florida

**Zip:** 32827

**Location 40:**

**City:** Pensacola

**Country:** United States

**Facility:** Nemours Children's Clinic - Pensacola

**State:** Florida

**Zip:** 32504

**Location 41:**

**City:** Saint Petersburg

**Country:** United States

**Facility:** Johns Hopkins All Children's Hospital

**State:** Florida

**Zip:** 33701

**Location 42:**

**City:** Tampa

**Country:** United States

**Facility:** Tampa General Hospital

**State:** Florida

**Zip:** 33606

**Location 43:**

**City:** Tampa

**Country:** United States

**Facility:** Saint Joseph's Hospital/Children's Hospital-Tampa

**State:** Florida

**Zip:** 33607

**Location 44:**

**City:** West Palm Beach

**Country:** United States

**Facility:** Saint Mary's Hospital

**State:** Florida

**Zip:** 33407

**Location 45:**

**City:** Atlanta

**Country:** United States

**Facility:** Children's Healthcare of Atlanta - Egleston

**State:** Georgia

**Zip:** 30322

**Location 46:**

**City:** Savannah

**Country:** United States

**Facility:** Memorial Health University Medical Center

**State:** Georgia

**Zip:** 31404

**Location 47:**

**City:** Honolulu

**Country:** United States

**Facility:** University of Hawaii Cancer Center

**State:** Hawaii

**Zip:** 96813

**Location 48:**

**City:** Honolulu

**Country:** United States

**Facility:** Kapiolani Medical Center for Women and Children

**State:** Hawaii

**Zip:** 96826

**Location 49:**

**City:** Boise

**Country:** United States

**Facility:** Saint Luke's Mountain States Tumor Institute

**State:** Idaho

**Zip:** 83712

**Location 50:**

**City:** Chicago

**Country:** United States

**Facility:** Lurie Children's Hospital-Chicago

**State:** Illinois

**Zip:** 60611

**Location 51:**

**City:** Chicago

**Country:** United States

**Facility:** University of Illinois

**State:** Illinois

**Zip:** 60612

**Location 52:**

**City:** Chicago

**Country:** United States

**Facility:** University of Chicago Comprehensive Cancer Center

**State:** Illinois

**Zip:** 60637

**Location 53:**

**City:** Maywood

**Country:** United States

**Facility:** Loyola University Medical Center

**State:** Illinois

**Zip:** 60153

**Location 54:**

**City:** Park Ridge

**Country:** United States

**Facility:** Advocate Children's Hospital-Park Ridge

**State:** Illinois

**Zip:** 60068

**Location 55:**

**City:** Park Ridge

**Country:** United States

**Facility:** Advocate Lutheran General Hospital

**State:** Illinois

**Zip:** 60068

**Location 56:**

**City:** Peoria

**Country:** United States

**Facility:** Saint Jude Midwest Affiliate

**State:** Illinois

**Zip:** 61637

**Location 57:**

**City:** Springfield

**Country:** United States

**Facility:** Southern Illinois University School of Medicine

**State:** Illinois

**Zip:** 62702

**Location 58:**

**City:** Indianapolis

**Country:** United States

**Facility:** Riley Hospital for Children

**State:** Indiana

**Zip:** 46202

**Location 59:**

**City:** Indianapolis

**Country:** United States

**Facility:** Saint Vincent Hospital and Health Care Center

**State:** Indiana

**Zip:** 46260

**Location 60:**

**City:** Des Moines

**Country:** United States

**Facility:** Blank Children's Hospital

**State:** Iowa

**Zip:** 50309

**Location 61:**

**City:** Iowa City

**Country:** United States

**Facility:** University of Iowa/Holden Comprehensive Cancer Center

**State:** Iowa

**Zip:** 52242

**Location 62:**

**City:** Kansas City

**Country:** United States

**Facility:** University of Kansas Cancer Center

**State:** Kansas

**Zip:** 66160

**Location 63:**

**City:** Lexington

**Country:** United States

**Facility:** University of Kentucky/Markey Cancer Center

**State:** Kentucky

**Zip:** 40536

**Location 64:**

**City:** Louisville

**Country:** United States

**Facility:** Norton Children's Hospital

**State:** Kentucky

**Zip:** 40202

**Location 65:**

**City:** New Orleans

**Country:** United States

**Facility:** Tulane University Health Sciences Center

**State:** Louisiana

**Zip:** 70112

**Location 66:**

**City:** New Orleans

**Country:** United States

**Facility:** Children's Hospital New Orleans

**State:** Louisiana

**Zip:** 70118

**Location 67:**

**City:** New Orleans

**Country:** United States

**Facility:** Ochsner Medical Center Jefferson

**State:** Louisiana

**Zip:** 70121

**Location 68:**

**City:** Scarborough

**Country:** United States

**Facility:** Maine Children's Cancer Program

**State:** Maine

**Zip:** 04074

**Location 69:**

**City:** Baltimore

**Country:** United States

**Facility:** Sinai Hospital of Baltimore

**State:** Maryland

**Zip:** 21215

**Location 70:**

**City:** Bethesda

**Country:** United States

**Facility:** Walter Reed National Military Medical Center

**State:** Maryland

**Zip:** 20889-5600

**Location 71:**

**City:** Boston

**Country:** United States

**Facility:** Dana-Farber Cancer Institute

**State:** Massachusetts

**Zip:** 02215

**Location 72:**

**City:** Springfield

**Country:** United States

**Facility:** Baystate Medical Center

**State:** Massachusetts

**Zip:** 01199

**Location 73:**

**City:** Ann Arbor

**Country:** United States

**Facility:** C S Mott Children's Hospital

**State:** Michigan

**Zip:** 48109

**Location 74:**

**City:** Detroit

**Country:** United States

**Facility:** Wayne State University/Karmanos Cancer Institute

**State:** Michigan

**Zip:** 48201

**Location 75:**

**City:** Detroit

**Country:** United States

**Facility:** Saint John Hospital and Medical Center

**State:** Michigan

**Zip:** 48236

**Location 76:**

**City:** East Lansing

**Country:** United States

**Facility:** Michigan State University Clinical Center

**State:** Michigan

**Zip:** 48824-7016

**Location 77:**

**City:** Flint

**Country:** United States

**Facility:** Hurley Medical Center

**State:** Michigan

**Zip:** 48503

**Location 78:**

**City:** Grand Rapids

**Country:** United States

**Facility:** Helen DeVos Children's Hospital at Spectrum Health

**State:** Michigan

**Zip:** 49503

**Location 79:**

**City:** Kalamazoo

**Country:** United States

**Facility:** Bronson Methodist Hospital

**State:** Michigan

**Zip:** 49007

**Location 80:**

**City:** Kalamazoo

**Country:** United States

**Facility:** Kalamazoo Center for Medical Studies

**State:** Michigan

**Zip:** 49008

**Location 81:**

**City:** Minneapolis

**Country:** United States

**Facility:** Children's Hospitals and Clinics of Minnesota - Minneapolis

**State:** Minnesota

**Zip:** 55404

**Location 82:**

**City:** Minneapolis

**Country:** United States

**Facility:** University of Minnesota/Masonic Cancer Center

**State:** Minnesota

**Zip:** 55455

**Location 83:**

**City:** Rochester

**Country:** United States

**Facility:** Mayo Clinic

**State:** Minnesota

**Zip:** 55905

**Location 84:**

**City:** Jackson

**Country:** United States

**Facility:** University of Mississippi Medical Center

**State:** Mississippi

**Zip:** 39216

**Location 85:**

**City:** Columbia

**Country:** United States

**Facility:** Columbia Regional

**State:** Missouri

**Zip:** 65201

**Location 86:**

**City:** Kansas City

**Country:** United States

**Facility:** The Childrens Mercy Hospital

**State:** Missouri

**Zip:** 64108

**Location 87:**

**City:** Saint Louis

**Country:** United States

**Facility:** Cardinal Glennon Children's Medical Center

**State:** Missouri

**Zip:** 63104

**Location 88:**

**City:** Saint Louis

**Country:** United States

**Facility:** Washington University School of Medicine

**State:** Missouri

**Zip:** 63110

**Location 89:**

**City:** Omaha

**Country:** United States

**Facility:** Children's Hospital and Medical Center of Omaha

**State:** Nebraska

**Zip:** 68114

**Location 90:**

**City:** Omaha

**Country:** United States

**Facility:** University of Nebraska Medical Center

**State:** Nebraska

**Zip:** 68198

**Location 91:**

**City:** Las Vegas

**Country:** United States

**Facility:** Nevada Cancer Research Foundation CCOP

**State:** Nevada

**Zip:** 89106

**Location 92:**

**City:** Las Vegas

**Country:** United States

**Facility:** Children's Specialty Center of Nevada II

**State:** Nevada

**Zip:** 89109

**Location 93:**

**City:** Las Vegas

**Country:** United States

**Facility:** Sunrise Hospital and Medical Center

**State:** Nevada

**Zip:** 89109

**Location 94:**

**City:** Hackensack

**Country:** United States

**Facility:** Hackensack University Medical Center

**State:** New Jersey

**Zip:** 07601

**Location 95:**

**City:** Livingston

**Country:** United States

**Facility:** Saint Barnabas Medical Center

**State:** New Jersey

**Zip:** 07039

**Location 96:**

**City:** Morristown

**Country:** United States

**Facility:** Morristown Medical Center

**State:** New Jersey

**Zip:** 07960

**Location 97:**

**City:** New Brunswick

**Country:** United States

**Facility:** Saint Peter's University Hospital

**State:** New Jersey

**Zip:** 08901

**Location 98:**

**City:** New Brunswick

**Country:** United States

**Facility:** Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital

**State:** New Jersey

**Zip:** 08903

**Location 99:**

**City:** Newark

**Country:** United States

**Facility:** Newark Beth Israel Medical Center

**State:** New Jersey

**Zip:** 07112

**Location 100:**

**City:** Paterson

**Country:** United States

**Facility:** Saint Joseph's Regional Medical Center

**State:** New Jersey

**Zip:** 07503

**Location 101:**

**City:** Summit

**Country:** United States

**Facility:** Overlook Hospital

**State:** New Jersey

**Zip:** 07902

**Location 102:**

**City:** Albuquerque

**Country:** United States

**Facility:** University of New Mexico Cancer Center

**State:** New Mexico

**Zip:** 87102

**Location 103:**

**City:** Albany

**Country:** United States

**Facility:** Albany Medical Center

**State:** New York

**Zip:** 12208

**Location 104:**

**City:** Bronx

**Country:** United States

**Facility:** Montefiore Medical Center - Moses Campus

**State:** New York

**Zip:** 10467

**Location 105:**

**City:** Brooklyn

**Country:** United States

**Facility:** Brooklyn Hospital Center

**State:** New York

**Zip:** 11201

**Location 106:**

**City:** Brooklyn

**Country:** United States

**Facility:** Maimonides Medical Center

**State:** New York

**Zip:** 11219

**Location 107:**

**City:** Buffalo

**Country:** United States

**Facility:** Roswell Park Cancer Institute

**State:** New York

**Zip:** 14263

**Location 108:**

**City:** Mineola

**Country:** United States

**Facility:** NYU Winthrop Hospital

**State:** New York

**Zip:** 11501

**Location 109:**

**City:** New Hyde Park

**Country:** United States

**Facility:** The Steven and Alexandra Cohen Children's Medical Center of New York

**State:** New York

**Zip:** 11040

**Location 110:**

**City:** New York

**Country:** United States

**Facility:** Laura and Isaac Perlmutter Cancer Center at NYU Langone

**State:** New York

**Zip:** 10016

**Location 111:**

**City:** New York

**Country:** United States

**Facility:** Mount Sinai Hospital

**State:** New York

**Zip:** 10029

**Location 112:**

**City:** New York

**Country:** United States

**Facility:** Columbia University/Herbert Irving Cancer Center

**State:** New York

**Zip:** 10032

**Location 113:**

**City:** Rochester

**Country:** United States

**Facility:** University of Rochester

**State:** New York

**Zip:** 14642

**Location 114:**

**City:** Stony Brook

**Country:** United States

**Facility:** Stony Brook University Medical Center

**State:** New York

**Zip:** 11794

**Location 115:**

**City:** Syracuse

**Country:** United States

**Facility:** State University of New York Upstate Medical University

**State:** New York

**Zip:** 13210

**Location 116:**

**City:** Valhalla

**Country:** United States

**Facility:** New York Medical College

**State:** New York

**Zip:** 10595

**Location 117:**

**City:** Asheville

**Country:** United States

**Facility:** Mission Hospital Inc-Memorial Campus

**State:** North Carolina

**Zip:** 28801

**Location 118:**

**City:** Chapel Hill

**Country:** United States

**Facility:** UNC Lineberger Comprehensive Cancer Center

**State:** North Carolina

**Zip:** 27599

**Location 119:**

**City:** Charlotte

**Country:** United States

**Facility:** Carolinas Medical Center/Levine Cancer Institute

**State:** North Carolina

**Zip:** 28203

**Location 120:**

**City:** Charlotte

**Country:** United States

**Facility:** Novant Health Presbyterian Medical Center

**State:** North Carolina

**Zip:** 28204

**Location 121:**

**City:** Durham

**Country:** United States

**Facility:** Duke University Medical Center

**State:** North Carolina

**Zip:** 27710

**Location 122:**

**City:** Winston-Salem

**Country:** United States

**Facility:** Wake Forest University Health Sciences

**State:** North Carolina

**Zip:** 27157

**Location 123:**

**City:** Fargo

**Country:** United States

**Facility:** Sanford Broadway Medical Center

**State:** North Dakota

**Zip:** 58122

**Location 124:**

**City:** Akron

**Country:** United States

**Facility:** Children's Hospital Medical Center of Akron

**State:** Ohio

**Zip:** 44308

**Location 125:**

**City:** Cincinnati

**Country:** United States

**Facility:** Cincinnati Children's Hospital Medical Center

**State:** Ohio

**Zip:** 45229

**Location 126:**

**City:** Cleveland

**Country:** United States

**Facility:** Rainbow Babies and Childrens Hospital

**State:** Ohio

**Zip:** 44106

**Location 127:**

**City:** Cleveland

**Country:** United States

**Facility:** Cleveland Clinic Foundation

**State:** Ohio

**Zip:** 44195

**Location 128:**

**City:** Columbus

**Country:** United States

**Facility:** Nationwide Children's Hospital

**State:** Ohio

**Zip:** 43205

**Location 129:**

**City:** Dayton

**Country:** United States

**Facility:** Dayton Children's Hospital

**State:** Ohio

**Zip:** 45404

**Location 130:**

**City:** Toledo

**Country:** United States

**Facility:** Mercy Children's Hospital

**State:** Ohio

**Zip:** 43608

**Location 131:**

**City:** Youngstown

**Country:** United States

**Facility:** Tod Children's Hospital - Forum Health

**State:** Ohio

**Zip:** 44501

**Location 132:**

**City:** Oklahoma City

**Country:** United States

**Facility:** University of Oklahoma Health Sciences Center

**State:** Oklahoma

**Zip:** 73104

**Location 133:**

**City:** Portland

**Country:** United States

**Facility:** Legacy Emanuel Children's Hospital

**State:** Oregon

**Zip:** 97227

**Location 134:**

**City:** Portland

**Country:** United States

**Facility:** Legacy Emanuel Hospital and Health Center

**State:** Oregon

**Zip:** 97227

**Location 135:**

**City:** Portland

**Country:** United States

**Facility:** Oregon Health and Science University

**State:** Oregon

**Zip:** 97239

**Location 136:**

**City:** Bethlehem

**Country:** United States

**Facility:** Lehigh Valley Hospital - Muhlenberg

**State:** Pennsylvania

**Zip:** 18017

**Location 137:**

**City:** Danville

**Country:** United States

**Facility:** Geisinger Medical Center

**State:** Pennsylvania

**Zip:** 17822

**Location 138:**

**City:** Hershey

**Country:** United States

**Facility:** Penn State Children's Hospital

**State:** Pennsylvania

**Zip:** 17033

**Location 139:**

**City:** Philadelphia

**Country:** United States

**Facility:** Children's Hospital of Philadelphia

**State:** Pennsylvania

**Zip:** 19104

**Location 140:**

**City:** Philadelphia

**Country:** United States

**Facility:** Saint Christopher's Hospital for Children

**State:** Pennsylvania

**Zip:** 19134

**Location 141:**

**City:** Pittsburgh

**Country:** United States

**Facility:** Children's Hospital of Pittsburgh of UPMC

**State:** Pennsylvania

**Zip:** 15224

**Location 142:**

**City:** Charleston

**Country:** United States

**Facility:** Medical University of South Carolina

**State:** South Carolina

**Zip:** 29425

**Location 143:**

**City:** Columbia

**Country:** United States

**Facility:** Palmetto Health Richland

**State:** South Carolina

**Zip:** 29203

**Location 144:**

**City:** Greenville

**Country:** United States

**Facility:** BI-LO Charities Children's Cancer Center

**State:** South Carolina

**Zip:** 29605

**Location 145:**

**City:** Greenville

**Country:** United States

**Facility:** Greenville Cancer Treatment Center

**State:** South Carolina

**Zip:** 29605

**Location 146:**

**City:** Sioux Falls

**Country:** United States

**Facility:** Sanford USD Medical Center - Sioux Falls

**State:** South Dakota

**Zip:** 57117-5134

**Location 147:**

**City:** Chattanooga

**Country:** United States

**Facility:** T C Thompson Children's Hospital

**State:** Tennessee

**Zip:** 37403

**Location 148:**

**City:** Johnson City

**Country:** United States

**Facility:** East Tennessee State University

**State:** Tennessee

**Zip:** 37614-0054

**Location 149:**

**City:** Knoxville

**Country:** United States

**Facility:** East Tennessee Childrens Hospital

**State:** Tennessee

**Zip:** 37916

**Location 150:**

**City:** Nashville

**Country:** United States

**Facility:** Vanderbilt University/Ingram Cancer Center

**State:** Tennessee

**Zip:** 37232

**Location 151:**

**City:** Amarillo

**Country:** United States

**Facility:** Texas Tech University Health Sciences Center-Amarillo

**State:** Texas

**Zip:** 79106

**Location 152:**

**City:** Austin

**Country:** United States

**Facility:** Dell Children's Medical Center of Central Texas

**State:** Texas

**Zip:** 78723

**Location 153:**

**City:** Corpus Christi

**Country:** United States

**Facility:** Driscoll Children's Hospital

**State:** Texas

**Zip:** 78411

**Location 154:**

**City:** Dallas

**Country:** United States

**Facility:** Medical City Dallas Hospital

**State:** Texas

**Zip:** 75230

**Location 155:**

**City:** Fort Sam Houston

**Country:** United States

**Facility:** Brooke Army Medical Center

**State:** Texas

**Zip:** 78234

**Location 156:**

**City:** Fort Worth

**Country:** United States

**Facility:** Cook Children's Medical Center

**State:** Texas

**Zip:** 76104

**Location 157:**

**City:** Houston

**Country:** United States

**Facility:** Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

**State:** Texas

**Zip:** 77030

**Location 158:**

**City:** Lubbock

**Country:** United States

**Facility:** Covenant Children's Hospital

**State:** Texas

**Zip:** 79410

**Location 159:**

**City:** San Antonio

**Country:** United States

**Facility:** Methodist Children's Hospital of South Texas

**State:** Texas

**Zip:** 78229

**Location 160:**

**City:** San Antonio

**Country:** United States

**Facility:** University of Texas Health Science Center at San Antonio

**State:** Texas

**Zip:** 78229

**Location 161:**

**City:** Temple

**Country:** United States

**Facility:** Scott and White Memorial Hospital

**State:** Texas

**Zip:** 76508

**Location 162:**

**City:** Salt Lake City

**Country:** United States

**Facility:** Primary Children's Hospital

**State:** Utah

**Zip:** 84113

**Location 163:**

**City:** Burlington

**Country:** United States

**Facility:** University of Vermont College of Medicine

**State:** Vermont

**Zip:** 05405

**Location 164:**

**City:** Falls Church

**Country:** United States

**Facility:** Inova Fairfax Hospital

**State:** Virginia

**Zip:** 22042

**Location 165:**

**City:** Norfolk

**Country:** United States

**Facility:** Children's Hospital of The King's Daughters

**State:** Virginia

**Zip:** 23507

**Location 166:**

**City:** Roanoke

**Country:** United States

**Facility:** Carilion Clinic Children's Hospital

**State:** Virginia

**Zip:** 24014

**Location 167:**

**City:** Seattle

**Country:** United States

**Facility:** Seattle Children's Hospital

**State:** Washington

**Zip:** 98105

**Location 168:**

**City:** Spokane

**Country:** United States

**Facility:** Providence Sacred Heart Medical Center and Children's Hospital

**State:** Washington

**Zip:** 99204

**Location 169:**

**City:** Tacoma

**Country:** United States

**Facility:** Mary Bridge Children's Hospital and Health Center

**State:** Washington

**Zip:** 98405

**Location 170:**

**City:** Tacoma

**Country:** United States

**Facility:** Madigan Army Medical Center

**State:** Washington

**Zip:** 98431

**Location 171:**

**City:** Charleston

**Country:** United States

**Facility:** West Virginia University Charleston Division

**State:** West Virginia

**Zip:** 25304

**Location 172:**

**City:** Green Bay

**Country:** United States

**Facility:** Saint Vincent Hospital Cancer Center Green Bay

**State:** Wisconsin

**Zip:** 54301

**Location 173:**

**City:** Madison

**Country:** United States

**Facility:** University of Wisconsin Hospital and Clinics

**State:** Wisconsin

**Zip:** 53792

**Location 174:**

**City:** Marshfield

**Country:** United States

**Facility:** Marshfield Clinic

**State:** Wisconsin

**Zip:** 54449

**Location 175:**

**City:** Milwaukee

**Country:** United States

**Facility:** Children's Hospital of Wisconsin

**State:** Wisconsin

**Zip:** 53226

**Location 176:**

**City:** North Adelaide

**Country:** Australia

**Facility:** Women's and Children's Hospital-Adelaide

**State:** South Australia

**Zip:** 5006

**Location 177:**

**City:** Perth

**Country:** Australia

**Facility:** Princess Margaret Hospital for Children

**State:** Western Australia

**Zip:** 6008

**Location 178:**

**City:** Edmonton

**Country:** Canada

**Facility:** University of Alberta Hospital

**State:** Alberta

**Zip:** T6G 2B7

**Location 179:**

**City:** Vancouver

**Country:** Canada

**Facility:** British Columbia Children's Hospital

**State:** British Columbia

**Zip:** V6H 3V4

**Location 180:**

**City:** Winnipeg

**Country:** Canada

**Facility:** CancerCare Manitoba

**State:** Manitoba

**Zip:** R3E 0V9

**Location 181:**

**City:** Halifax

**Country:** Canada

**Facility:** IWK Health Centre

**State:** Nova Scotia

**Zip:** B3K 6R8

**Location 182:**

**City:** Hamilton

**Country:** Canada

**Facility:** McMaster Children's Hospital at Hamilton Health Sciences

**State:** Ontario

**Zip:** L8N 3Z5

**Location 183:**

**City:** Kingston

**Country:** Canada

**Facility:** Kingston Health Sciences Centre

**State:** Ontario

**Zip:** K7L 2V7

**Location 184:**

**City:** Ottawa

**Country:** Canada

**Facility:** Children's Hospital of Eastern Ontario

**State:** Ontario

**Zip:** K1H 8L1

**Location 185:**

**City:** Toronto

**Country:** Canada

**Facility:** Hospital for Sick Children

**State:** Ontario

**Zip:** M5G 1X8

**Location 186:**

**City:** Montreal

**Country:** Canada

**Facility:** The Montreal Children's Hospital of the MUHC

**State:** Quebec

**Zip:** H3H 1P3

**Location 187:**

**City:** Montreal

**Country:** Canada

**Facility:** Centre Hospitalier Universitaire Sainte-Justine

**State:** Quebec

**Zip:** H3T 1C5

**Location 188:**

**City:** Regina

**Country:** Canada

**Facility:** Allan Blair Cancer Centre

**State:** Saskatchewan

**Zip:** S4T 7T1

**Location 189:**

**City:** Saskatoon

**Country:** Canada

**Facility:** Saskatoon Cancer Centre

**State:** Saskatchewan

**Zip:** S7N 4H4

**Location 190:**

**City:** Grafton

**Country:** New Zealand

**Facility:** Starship Children's Hospital

**State:** Auckland

**Zip:** 1145

**Location 191:**

**City:** San Juan

**Country:** Puerto Rico

**Facility:** San Jorge Children's Hospital

**Zip:** 00912

**Location 192:**

**City:** Geneva

**Country:** Switzerland

**Facility:** Swiss Pediatric Oncology Group - Geneva

**Zip:** 1205

#### Overall Officials

**Official 1:**

**Affiliation:** Children's Oncology Group

**Name:** Nilsa Ramirez

**Role:** PRINCIPAL_INVESTIGATOR

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000009370

- Term: Neoplasms by Histologic Type

- ID: D000006402

- Term: Hematologic Diseases

- ID: D000007945

- Term: Leukemia, Lymphoid

- ID: D000008232

- Term: Lymphoproliferative Disorders

- ID: D000008206

- Term: Lymphatic Diseases

- ID: D000007160

- Term: Immunoproliferative Disorders

- ID: D000007154

- Term: Immune System Diseases

- ID: D000015448

- Term: Leukemia, B-Cell

- ID: D000002908

- Term: Chronic Disease

- ID: D000020969

- Term: Disease Attributes

- ID: D000010335

- Term: Pathologic Processes

- ID: D000009196

- Term: Myeloproliferative Disorders

- ID: D000001855

- Term: Bone Marrow Diseases

- ID: D000054437

- Term: Myelodysplastic-Myeloproliferative Diseases

- ID: D000015458

- Term: Leukemia, T-Cell

- ID: D000034721

- Term: Mastocytosis, Systemic

- ID: D000008415

- Term: Mastocytosis

- ID: D000090362

- Term: Mast Cell Activation Disorders

### Condition Browse Module - Browse Branches

- Abbrev: BC04

- Name: Neoplasms

- Abbrev: BC15

- Name: Blood and Lymph Conditions

- Abbrev: All

- Name: All Conditions

- Abbrev: BC20

- Name: Immune System Diseases

- Abbrev: BC23

- Name: Symptoms and General Pathology

- Abbrev: Rare

- Name: Rare Diseases

### Condition Browse Module - Browse Leaves

- ID: M10945

- Name: Leukemia

- Relevance: HIGH

- As Found: Leukemia

- ID: M10955

- Name: Leukemia, Myeloid

- Relevance: HIGH

- As Found: Myeloid Leukemia

- ID: M18127

- Name: Leukemia, Myeloid, Acute

- Relevance: HIGH

- As Found: Acute Myeloid Leukemia

- ID: M10951

- Name: Leukemia, Lymphoid

- Relevance: LOW

- As Found: Unknown

- ID: M18116

- Name: Leukemia, Lymphocytic, Chronic, B-Cell

- Relevance: HIGH

- As Found: Chronic Lymphocytic Leukemia

- ID: M18123

- Name: Leukemia, Myelogenous, Chronic, BCR-ABL Positive

- Relevance: HIGH

- As Found: Chronic Myelogenous Leukemia, BCR-ABL1 Positive

- ID: M27585

- Name: Precursor Cell Lymphoblastic Leukemia-Lymphoma

- Relevance: HIGH

- As Found: Acute Lymphoblastic Leukemia

- ID: M12307

- Name: Neoplasm Metastasis

- Relevance: LOW

- As Found: Unknown

- ID: M18122

- Name: Leukemia, Prolymphocytic

- Relevance: HIGH

- As Found: Prolymphocytic Leukemia

- ID: M27706

- Name: Leukemia, Myelomonocytic, Juvenile

- Relevance: HIGH

- As Found: Juvenile Myelomonocytic Leukemia

- ID: M10950

- Name: Leukemia, Hairy Cell

- Relevance: HIGH

- As Found: Hairy cell leukemia

- ID: M27552

- Name: Leukemia, Large Granular Lymphocytic

- Relevance: HIGH

- As Found: T-cell large granular lymphocyte leukemia

- ID: M10952

- Name: Leukemia, Mast-Cell

- Relevance: HIGH

- As Found: Mast cell leukemia

- ID: M11220

- Name: Lymphoma

- Relevance: LOW

- As Found: Unknown

- ID: M27708

- Name: Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

- Relevance: HIGH

- As Found: Atypical chronic myeloid leukemia

- ID: M12315

- Name: Neoplasms by Histologic Type

- Relevance: LOW

- As Found: Unknown

- ID: M9490

- Name: Hematologic Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M11225

- Name: Lymphoproliferative Disorders

- Relevance: LOW

- As Found: Unknown

- ID: M11203

- Name: Lymphatic Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M10206

- Name: Immunoproliferative Disorders

- Relevance: LOW

- As Found: Unknown

- ID: M10200

- Name: Immune System Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M18115

- Name: Leukemia, B-Cell

- Relevance: LOW

- As Found: Unknown

- ID: M6147

- Name: Chronic Disease

- Relevance: LOW

- As Found: Unknown

- ID: M22700

- Name: Disease Attributes

- Relevance: LOW

- As Found: Unknown

- ID: M12149

- Name: Myeloproliferative Disorders

- Relevance: LOW

- As Found: Unknown

- ID: M5134

- Name: Bone Marrow Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M27707

- Name: Myelodysplastic-Myeloproliferative Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M18119

- Name: Leukemia, T-Cell

- Relevance: LOW

- As Found: Unknown

- ID: M11399

- Name: Mastocytosis

- Relevance: LOW

- As Found: Unknown

- ID: M24449

- Name: Mastocytosis, Systemic

- Relevance: LOW

- As Found: Unknown

- ID: M2776

- Name: Mast Cell Activation Disorders

- Relevance: LOW

- As Found: Unknown

- ID: T3995

- Name: Myeloid Leukemia

- Relevance: HIGH

- As Found: Myeloid Leukemia

- ID: T182

- Name: Acute Myeloid Leukemia

- Relevance: HIGH

- As Found: Acute Myeloid Leukemia

- ID: T188

- Name: Acute Non Lymphoblastic Leukemia

- Relevance: HIGH

- As Found: Acute Myeloid Leukemia

- ID: T1308

- Name: Chronic Lymphocytic Leukemia

- Relevance: HIGH

- As Found: Chronic Lymphocytic Leukemia

- ID: T1303

- Name: Chronic Graft Versus Host Disease

- Relevance: HIGH

- As Found: Chronic

- ID: T1309

- Name: Chronic Myeloid Leukemia

- Relevance: HIGH

- As Found: Chronic Myeloid Leukemia

- ID: T175

- Name: Acute Lymphoblastic Leukemia

- Relevance: HIGH

- As Found: Acute Lymphoblastic Leukemia

- ID: T3533

- Name: Lymphoblastic Lymphoma

- Relevance: LOW

- As Found: Unknown

- ID: T170

- Name: Acute Graft Versus Host Disease

- Relevance: LOW

- As Found: Unknown

- ID: T1134

- Name: Childhood Acute Lymphoblastic Leukemia

- Relevance: HIGH

- As Found: Childhood acute lymphoblastic leukemia

- ID: T1310

- Name: Chronic Myelomonocytic Leukemia

- Relevance: HIGH

- As Found: Juvenile Myelomonocytic Leukemia

- ID: T3174

- Name: Juvenile Myelomonocytic Leukemia

- Relevance: HIGH

- As Found: Juvenile Myelomonocytic Leukemia

- ID: T2650

- Name: Hairy Cell Leukemia

- Relevance: HIGH

- As Found: Hairy cell leukemia

- ID: T238

- Name: Aggressive NK Cell Leukemia

- Relevance: HIGH

- As Found: Large granular lymphocyte leukemia

- ID: T5568

- Name: T-cell Large Granular Lymphocyte Leukemia

- Relevance: HIGH

- As Found: T-cell large granular lymphocyte leukemia

- ID: T3543

- Name: Lymphosarcoma

- Relevance: LOW

- As Found: Unknown

- ID: T1311

- Name: Chronic Myeloproliferative Disorders

- Relevance: LOW

- As Found: Unknown

- ID: T3994

- Name: Myelodysplastic/myeloproliferative Disease

- Relevance: LOW

- As Found: Unknown

- ID: T3626

- Name: Mastocytosis

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000007938

- Term: Leukemia

- ID: D000009369

- Term: Neoplasms

- ID: D000007951

- Term: Leukemia, Myeloid

- ID: D000015470

- Term: Leukemia, Myeloid, Acute

- ID: D000054198

- Term: Precursor Cell Lymphoblastic Leukemia-Lymphoma

- ID: D000015451

- Term: Leukemia, Lymphocytic, Chronic, B-Cell

- ID: D000015464

- Term: Leukemia, Myelogenous, Chronic, BCR-ABL Positive

- ID: D000007943

- Term: Leukemia, Hairy Cell

- ID: D000015463

- Term: Leukemia, Prolymphocytic

- ID: D000054438

- Term: Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

- ID: D000054429

- Term: Leukemia, Myelomonocytic, Juvenile

- ID: D000054066

- Term: Leukemia, Large Granular Lymphocytic

- ID: D000007946

- Term: Leukemia, Mast-Cell

### Misc Info Module

- Version Holder: 2024-05-24
