## Protocol Section
### Identification Module
**NCT ID:** NCT01502579

**Brief Title:** An Observational Study of IgA Nephropathy: Pathological Variants and Clinical Data

**Official Title:** An Observational Study of the Relationship Between Pathological Variants and Clinical Data at Presentation and Follow-up in IgA Nephropathy

#### Organization Study ID Info
**ID:** GGH201106
#### Organization
**Class:** OTHER
**Full Name:** Guangdong Provincial People's Hospital
### Status Module
#### Completion Date
**Date:** 2013-08

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2013-08-28

**Type:** ESTIMATED

**Last Update Submit Date:** 2013-08-27

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2013-08

**Type:** ACTUAL

#### Start Date
**Date:** 2011-09

**Status Verified Date:** 2013-08

#### Study First Post Date
**Date:** 2011-12-30
**Type:** ESTIMATED
**Study First Submit Date:** 2011-12-29
**Study First Submit QC Date:** 2011-12-29
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Guangdong Provincial People's Hospital

#### Responsible Party

**Investigator Affiliation:** Guangdong Provincial People's Hospital

**Investigator Full Name:** Wei Shi

**Investigator Title:** Professor

**Type:** PRINCIPAL_INVESTIGATOR

### Oversight Module

**Oversight Has DMC:** True

### Description Module

**Brief Summary:** The pathological variants of IgA nephropathy identified by the Oxford classification may be related to the clinical data at presentation and follow-up, including proteinuria and renal function. This study is aimed to identify the potential relationship between pathological variants and clinical data in IgA nephropathy.

### Conditions Module

**Conditions:**

- IgA Nephropathy

**Keywords:**

- IgA nephropathy

### Design Module

#### Design Info

**Time Perspective:** PROSPECTIVE

#### Enrollment Info

**Count:** 603

**Type:** ACTUAL

**Study Type:** OBSERVATIONAL

### Outcomes Module

#### Primary Outcomes

**Measure:** glomerular filtration rate decline or end-stage renal disease or doubling of serum creatinine

**Time Frame:** after the biopsy

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* biopsy-proven IgA nephropathy;

Exclusion Criteria:

**Maximum Age:** 80 Years

**Minimum Age:** 18 Years

**Sampling Method:** PROBABILITY_SAMPLE

**Sex:** ALL

**Standard Ages:**

- ADULT

- OLDER_ADULT

**Study Population:** The population from which the cohort will be selected is these who have received renal biopsy in Guangdong General Hospital

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Guangzhou

**Country:** China

**Facility:** Guangdong General Hospital

**State:** Guangdong

**Zip:** 510080

#### Overall Officials

**Official 1:**

**Affiliation:** Guangdong Provincial People's Hospital

**Name:** Wei Shi, MD,PhD

**Role:** PRINCIPAL_INVESTIGATOR

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000014570

- Term: Urologic Diseases

- ID: D000052776

- Term: Female Urogenital Diseases

- ID: D000005261

- Term: Female Urogenital Diseases and Pregnancy Complications

- ID: D000091642

- Term: Urogenital Diseases

- ID: D000052801

- Term: Male Urogenital Diseases

- ID: D000005921

- Term: Glomerulonephritis

- ID: D000009393

- Term: Nephritis

- ID: D000001327

- Term: Autoimmune Diseases

- ID: D000007154

- Term: Immune System Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BXS

- Name: Urinary Tract, Sexual Organs, and Pregnancy Conditions

- Abbrev: All

- Name: All Conditions

- Abbrev: BC20

- Name: Immune System Diseases

- Abbrev: Rare

- Name: Rare Diseases

### Condition Browse Module - Browse Leaves

- ID: M10698

- Name: Kidney Diseases

- Relevance: HIGH

- As Found: Nephropathy

- ID: M9032

- Name: Glomerulonephritis, IGA

- Relevance: HIGH

- As Found: IgA Nephropathy

- ID: M9031

- Name: Glomerulonephritis

- Relevance: LOW

- As Found: Unknown

- ID: M17319

- Name: Urologic Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M2875

- Name: Urogenital Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M27093

- Name: Female Urogenital Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M14127

- Name: Pregnancy Complications

- Relevance: LOW

- As Found: Unknown

- ID: M8399

- Name: Female Urogenital Diseases and Pregnancy Complications

- Relevance: LOW

- As Found: Unknown

- ID: M27095

- Name: Male Urogenital Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M12338

- Name: Nephritis

- Relevance: LOW

- As Found: Unknown

- ID: M4629

- Name: Autoimmune Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M10200

- Name: Immune System Diseases

- Relevance: LOW

- As Found: Unknown

- ID: T3008

- Name: IgA Nephropathy

- Relevance: HIGH

- As Found: IgA Nephropathy

- ID: T2525

- Name: Glomerulonephritis

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000007674

- Term: Kidney Diseases

- ID: D000005922

- Term: Glomerulonephritis, IGA

### Intervention Browse Module - Browse Branches

- Abbrev: All

- Name: All Drugs and Chemicals

### Intervention Browse Module - Browse Leaves

- ID: M10118

- Name: Immunoglobulin A

- Relevance: LOW

- As Found: Unknown

### Misc Info Module

- Version Holder: 2024-05-24
