## Protocol Section
### Identification Module
**NCT ID:** NCT01563679

**Brief Title:** Analysis of Percutaneous Ablations for Cancer Treatment

**Official Title:** Prospective Analysis of Percutaneous Ablations for Cancer Treatment

#### Organization Study ID Info
**ID:** IRB00054905
#### Organization
**Class:** OTHER
**Full Name:** Emory University
#### Secondary ID Infos
**Domain:** Other
**ID:** RAD2160-11
**Type:** OTHER
### Status Module
#### Completion Date
**Date:** 2014-01

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2014-05-28

**Type:** ESTIMATED

**Last Update Submit Date:** 2014-05-23

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2014-01

**Type:** ACTUAL

#### Start Date
**Date:** 2012-02

**Status Verified Date:** 2014-05

#### Study First Post Date
**Date:** 2012-03-27
**Type:** ESTIMATED
**Study First Submit Date:** 2012-03-12
**Study First Submit QC Date:** 2012-03-23
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Emory University

#### Responsible Party

**Investigator Affiliation:** Emory University

**Investigator Full Name:** Hyun Kevin Kim

**Investigator Title:** Director of Interventional Radiology and Image-guided Medicine

**Type:** PRINCIPAL_INVESTIGATOR

### Oversight Module

**Oversight Has DMC:** True

### Description Module

**Brief Summary:** This is a study involving patients with cancer who are referred by their treating physician for percutaneous locoregional therapies.

Patient's clinical and radiology findings, pathology findings, survival, treatment responses, and complications after their locoregional therapy will be studied.

**Detailed Description:** The efficacy of the percutaneous and transarterial treatments for solid tumors will be studied. Prospective study on patients who receive percutaneous locoregional therapies, including radiofrequency ablation (RFA), cryoablation, microwave ablation, IRE and chemical ablation for treatment of cancer will be performed.

Preoperative clinic chart, procedure note, postoperative chart, pre- and post-operative CT, MRI or Ultrasound, angiographic findings, biopsy results and pathologic findings, will be reviewed. Patient survival, treatment responses, complications after the therapy will be collected from clinic visits and clinical encounters.

Patient overall performance status before and after procedures will be assessed using the Quality of Life questionnaire (SF-36™ Health Survey).

### Conditions Module

**Conditions:**

- Cancer

**Keywords:**

- cancer

- locoregional therapies

- RFA

- Cryoablation

- Microwave ablation

- chemical ablation

- Irreversible electroporation

### Design Module

#### Design Info

**Time Perspective:** PROSPECTIVE

#### Enrollment Info

**Count:** 26

**Type:** ACTUAL

**Study Type:** OBSERVATIONAL

### Outcomes Module

#### Primary Outcomes

**Description:** Patients will complete the QOL questionnare during their follow up visits after procedure. 1 month, 3 months, 6 months and 1 year.

**Measure:** Effect of percutaneous and transarterial treatments for cancer in quality of life

**Time Frame:** 1 year

#### Secondary Outcomes

**Description:** Patients will be followed up 1, 3, 6 and 1year intervals after procedure.

**Measure:** response rate to percutaneous and transarterial treatment for cancer

**Time Frame:** 1 month, 3 months, 6 months, 1 year.

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* 18yrs of age
* Cancer diagnosis
* Candidate for Locoregional therapy
* Willingness to sign informed consent

Exclusion Criteria:

* Unable to sign informed consent
* Patients not eligible for locoregional therapies

**Minimum Age:** 18 Years

**Sampling Method:** NON_PROBABILITY_SAMPLE

**Sex:** ALL

**Standard Ages:**

- ADULT

- OLDER_ADULT

**Study Population:** Patients who undergo ablative therapy procedures, in the Interventional Radiology department as part of a clinical treatment for cancer.

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Altanta

**Country:** United States

**Facility:** Emory University Hospital

**State:** Georgia

**Zip:** 30322

#### Overall Officials

**Official 1:**

**Affiliation:** Emory University

**Name:** Hyun S Kim, MD

**Role:** PRINCIPAL_INVESTIGATOR

## Derived Section

### Misc Info Module

- Version Holder: 2024-05-24
