## Protocol Section
### Identification Module
**NCT ID:** NCT05886179

**Brief Title:** COVID-19 IN CHILDREN IN NIGER, 2020

**Official Title:** Factors Associated With COVID-19 in Children Aged 0-15 Years in Niger, 2020

#### Organization Study ID Info
**ID:** CERMES
#### Organization
**Class:** OTHER
**Full Name:** Centre de Recherche Médicale et Sanitaire
### Status Module
#### Completion Date
**Date:** 2021-01-15

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2023-06-02

**Type:** ACTUAL

**Last Update Submit Date:** 2023-05-31

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2020-08-28

**Type:** ACTUAL

#### Start Date
**Date:** 2020-02-25

**Type:** ACTUAL

**Status Verified Date:** 2023-05

#### Study First Post Date
**Date:** 2023-06-02
**Type:** ACTUAL
**Study First Submit Date:** 2023-05-31
**Study First Submit QC Date:** 2023-05-31
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Centre de Recherche Médicale et Sanitaire

#### Responsible Party

**Investigator Affiliation:** Centre de Recherche Médicale et Sanitaire

**Investigator Full Name:** IDE AMADOU Habibatou

**Investigator Title:** Doctor

**Type:** PRINCIPAL_INVESTIGATOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** On January 30, 2020, the WHO declared COVID-19 a global health emergency. Children were affected with less severe forms. Niger had implemented measures in a context where children are a source of contamination. The objective was to determine the factors associated with COVID-19 in children in Niger from February to August 2020 through an analysis of the national database.

**Detailed Description:** We conducted an analytical cross-sectional study including all COVID-19 suspects in the database. We used Excel and Epi Info 7.2.4. software for data extraction and analysis. Frequencies and proportions were calculated, we estimated in a logistic regression the OR of association with their 95% confidence interval, the factors associated with COVID-19 at the threshold of p\<0.05.

Results: Of 572 notified suspected COVID-19 cases in children aged 0-15 years, 11.36% were positive. The median age of infected children was 10 years \[IQR: 5- 13 years\]. The sex ratio of males to females was 2.1. Children aged 11-15 years were 49.2%, 61.5% resided in Niamey, 4.6% had comorbidities. The notion of travel was 12.3% and 40% had a notion of contact, 24.4% had a fever, 23.2% had a cough, 18% were hospitalized and the case fatality was 1.5%. In etiological analysis, the factors associated with COVID-19 were sex ORa= 0.51 \[0.28-0.93\] p=0.028, the presence of symptoms ORa= 2.29 \[1.23-4.25\] p=0.008 and the notion of contact ORa= 0.32 \[0.13-0.77\] p=0.011.

exposed children were sensitive to COVID-19, all age groups were affected with a male predominance. We recommend barrier measures adapted to young people, early detection and management of infected children.

### Conditions Module

**Conditions:**

- to Contribute to a Better Control of COVID-19 in Children in Niger

**Keywords:**

- factors, COVID-19, children, database, Niger

### Design Module

#### Design Info

**Observational Model:** OTHER

**Time Perspective:** RETROSPECTIVE

#### Enrollment Info

**Count:** 572

**Type:** ACTUAL

**Study Type:** OBSERVATIONAL

### Arms Interventions Module

### Interventions

#### Intervention 1

**Description:** analytical cross-sectional study with retrospective collection of epidemiological surveillance data on COVID-19 in Niger.

**Name:** cross-sectional study

**Type:** OTHER

### Outcomes Module

#### Primary Outcomes

**Description:** The first step concerned the descriptive part where the frequencies, proportions, means and extreme values of the variables were calculated. Some of these variables were presented in the form of tables and graphs.

**Measure:** data base analysis

**Time Frame:** May 2021

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* Children aged 0-15 years suspected of having COVID-19 whose data were in the DSRE database were included

Exclusion Criteria:

* Children whose data is not complete

**Maximum Age:** 15 Years

**Minimum Age:** 0 Years

**Sampling Method:** NON_PROBABILITY_SAMPLE

**Sex:** ALL

**Standard Ages:**

- CHILD

**Study Population:** This was an analytical cross-sectional study with retrospective collection of epidemiological surveillance data on COVID-19 in Niger. The study period spanned six (6) months from February 25 to August 28, 2020. Children aged 0-15 years suspected of having COVID-19 whose data were in the DSRE database were included. We used the data extraction form that served as a secondary database containing only our variables of interest.

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Niamey

**Country:** Niger

**Facility:** IDE AMADOU Habibatou

**Zip:** BP: 10887, Niamey, Niger

### IPD Sharing Statement Module

**Description:** What is IPD ?

**IPD Sharing:** NO

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000011024

- Term: Pneumonia, Viral

- ID: D000011014

- Term: Pneumonia

- ID: D000012141

- Term: Respiratory Tract Infections

- ID: D000007239

- Term: Infections

- ID: D000014777

- Term: Virus Diseases

- ID: D000018352

- Term: Coronavirus Infections

- ID: D000003333

- Term: Coronaviridae Infections

- ID: D000030341

- Term: Nidovirales Infections

- ID: D000012327

- Term: RNA Virus Infections

- ID: D000008171

- Term: Lung Diseases

- ID: D000012140

- Term: Respiratory Tract Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC01

- Name: Infections

- Abbrev: BC08

- Name: Respiratory Tract (Lung and Bronchial) Diseases

- Abbrev: All

- Name: All Conditions

- Abbrev: BC23

- Name: Symptoms and General Pathology

### Condition Browse Module - Browse Leaves

- ID: M2561

- Name: COVID-19

- Relevance: HIGH

- As Found: COVID-19

- ID: M13904

- Name: Pneumonia

- Relevance: LOW

- As Found: Unknown

- ID: M13914

- Name: Pneumonia, Viral

- Relevance: LOW

- As Found: Unknown

- ID: M10283

- Name: Infections

- Relevance: LOW

- As Found: Unknown

- ID: M6368

- Name: Communicable Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M14978

- Name: Respiratory Tract Infections

- Relevance: LOW

- As Found: Unknown

- ID: M17522

- Name: Virus Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M20490

- Name: Coronavirus Infections

- Relevance: LOW

- As Found: Unknown

- ID: M6555

- Name: Coronaviridae Infections

- Relevance: LOW

- As Found: Unknown

- ID: M23685

- Name: Nidovirales Infections

- Relevance: LOW

- As Found: Unknown

- ID: M15149

- Name: RNA Virus Infections

- Relevance: LOW

- As Found: Unknown

- ID: M11168

- Name: Lung Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M14977

- Name: Respiratory Tract Diseases

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000086382

- Term: COVID-19

### Misc Info Module

- Version Holder: 2024-05-24
