## Protocol Section
### Identification Module
**NCT ID:** NCT05128279

**Acronym:** AIS

**Brief Title:** Adolescent and Young Adulte Scoliosis

**Official Title:** Analysis of Corrections of Adolescent and Young Adulte Scoliosis by Posterior Instrumentation

#### Organization Study ID Info
**ID:** 7961
#### Organization
**Class:** OTHER
**Full Name:** University Hospital, Strasbourg, France
### Status Module
#### Completion Date
**Date:** 2023-03-18

**Type:** ESTIMATED

#### Expanded Access Info
**Last Known Status:** RECRUITING
#### Last Update Post Date
**Date:** 2021-11-30

**Type:** ACTUAL

**Last Update Submit Date:** 2021-11-23

**Overall Status:** UNKNOWN

#### Primary Completion Date
**Date:** 2023-03

**Type:** ESTIMATED

#### Start Date
**Date:** 2020-10-28

**Type:** ACTUAL

**Status Verified Date:** 2021-10

#### Study First Post Date
**Date:** 2021-11-19
**Type:** ACTUAL
**Study First Submit Date:** 2021-10-20
**Study First Submit QC Date:** 2021-11-17
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** University Hospital, Strasbourg, France

#### Responsible Party

**Type:** SPONSOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** Thoracic hypocyphosis and greater lumbar lordosis after correction of idiopathic scoliosis in adolescents and young adults may adversely affect overall sagittal alignment and increase the risk of proximal junctional kyphosis.

The objective of this study is to analyze surgical corrections and maintenance of correction over time using modern posterior instrumentation strategies by comparing technical developments.

### Conditions Module

**Conditions:**

- Idiopathic Scoliosis

**Keywords:**

- Idiopathic scoliosis

- Thoracic hyperkyphosis

- Cyphosis

### Design Module

#### Design Info

**Observational Model:** CASE_CONTROL

**Time Perspective:** RETROSPECTIVE

#### Enrollment Info

**Count:** 150

**Type:** ESTIMATED

**Study Type:** OBSERVATIONAL

### Outcomes Module

#### Primary Outcomes

**Measure:** Study of corrections of adolescent and young adult scoliosis by posterior instrumentation

**Time Frame:** Files analysed retrospectively from January 01, 2010 to December 31, 2020 will be examined]

### Eligibility Module

**Eligibility Criteria:** Inclusion criteria:

* Major subjects\> 18 years old
* Subject with a surgical indication for arthrodesis and surgical correction of adolescent or young adult scoliosis
* Subject not having expressed his opposition, after information, to the reuse of his data for the purposes of this research.

Exclusion criteria:

* Subject having expressed opposition to participating in the study
* Subject under guardianship or guardianship
* Subject under safeguard of justice

**Minimum Age:** 18 Years

**Sampling Method:** NON_PROBABILITY_SAMPLE

**Sex:** ALL

**Standard Ages:**

- ADULT

- OLDER_ADULT

**Study Population:** Major subjects with a surgical indication for arthrodesis and surgical correction of adolescent or young adult scoliosis

### Contacts Locations Module

#### Central Contacts

**Contact 1:**

**Email:** YannPhilippe.CHARLES@chru-strasbourg.fr

**Name:** Yann Philippe CHARLES, MD, PhD

**Phone:** 33 3 68 76 52 68

**Role:** CONTACT

**Contact 2:**

**Email:** said.chayer@chru-strasbourg.fr

**Name:** Saïd CHAYER, PhD, HDR

**Role:** CONTACT

#### Locations

**Location 1:**

**City:** Strasbourg

**Contacts:**

***Contact 1:***

- **Email:** YannPhilippe.CHARLES@chru-strasbourg.fr

- **Name:** Yann Philippe CHARLES, MD, PhD

- **Phone:** 33 3 68 76 52 68

- **Role:** CONTACT

***Contact 2:***

- **Name:** Saïd CHAYER, PhD, HDR

- **Role:** CONTACT

***Contact 3:***

- **Name:** Yann Philippe CHARLES, MD, PhD

- **Role:** PRINCIPAL_INVESTIGATOR

***Contact 4:***

- **Name:** Nicolas TUZIN, Statistician

- **Role:** SUB_INVESTIGATOR

**Country:** France

**Facility:** Service de Chirurgie du Rachis - Hôpitaux Universitaires de Strasbourg

**Status:** RECRUITING

**Zip:** 67091

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000013121

- Term: Spinal Curvatures

- ID: D000013122

- Term: Spinal Diseases

- ID: D000001847

- Term: Bone Diseases

- ID: D000009140

- Term: Musculoskeletal Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC05

- Name: Musculoskeletal Diseases

- Abbrev: All

- Name: All Conditions

### Condition Browse Module - Browse Leaves

- ID: M15417

- Name: Scoliosis

- Relevance: HIGH

- As Found: Scoliosis

- ID: M10758

- Name: Kyphosis

- Relevance: LOW

- As Found: Unknown

- ID: M15918

- Name: Spinal Curvatures

- Relevance: LOW

- As Found: Unknown

- ID: M15919

- Name: Spinal Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M5126

- Name: Bone Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M12097

- Name: Musculoskeletal Diseases

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000012600

- Term: Scoliosis

### Misc Info Module

- Version Holder: 2024-05-24
