## Protocol Section
### Identification Module
**NCT ID:** NCT01358279

**Brief Title:** Transcranial Direct Current Stimulation for Migraine Attack

**Official Title:** Manho Kim, MD, PhD Professor, Neurology Seoul National University Hospital,

#### Organization Study ID Info
**ID:** 2009-4615-A
#### Organization
**Class:** OTHER
**Full Name:** Seoul National University Hospital
### Status Module
#### Completion Date
**Date:** 2011-03

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2016-10-25

**Type:** ESTIMATED

**Last Update Submit Date:** 2016-10-23

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2009-10

**Type:** ACTUAL

#### Start Date
**Date:** 2009-01

**Status Verified Date:** 2016-10

#### Study First Post Date
**Date:** 2011-05-23
**Type:** ESTIMATED
**Study First Submit Date:** 2011-05-18
**Study First Submit QC Date:** 2011-05-20
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Seoul National University Hospital

#### Responsible Party

**Investigator Affiliation:** Seoul National University Hospital

**Investigator Full Name:** Manho Kim

**Investigator Title:** Manho Kim, MD, PhD Professor, Neurology Seoul National University Hospital

**Type:** PRINCIPAL_INVESTIGATOR

### Description Module

**Brief Summary:** This study is conducted to investigate the therapeutic efficacy and safety of transcranial direct current stimulation (tDCS) over the primary motor cortex of patients with acute migraine attack.

### Conditions Module

**Conditions:**

- Acute Migraine

### Design Module

#### Design Info

**Allocation:** NA

**Intervention Model:** SINGLE_GROUP

##### Masking Info

**Masking:** NONE

**Primary Purpose:** TREATMENT

#### Enrollment Info

**Count:** 32

**Type:** ACTUAL

**Phases:**

- NA

**Study Type:** INTERVENTIONAL

### Arms Interventions Module

#### Arm Group 1

**Intervention Names:**

- Procedure: transcranial direct current stimulation

**Label:** migraine

**Type:** EXPERIMENTAL

### Interventions

#### Intervention 1

**Arm Group Labels:**

- migraine

**Description:** A constant current of 2 mA intensity applied for 20 min over C3 or C4

**Name:** transcranial direct current stimulation

**Type:** PROCEDURE

### Outcomes Module

#### Primary Outcomes

**Measure:** Number of participants who experienced pain relief of one level or more

**Time Frame:** at 2h post-treatment

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* Aged 17-70 years
* Migraine

  * With or without aura
  * The first attack of migraine was earlier than 50 years of age
  * One to 8 moderate to severe migraine attacks per month in the 2 months preceding the screening
* Willing and able to give written informed consent
* Able to read, comprehend and complete the diary form

Exclusion Criteria:

* Not able to distinguish between migraine and non-migraine headache
* Combined headache, including the tension type headache and medication overuse headache
* Pregnant, actively trying to become pregnant or breast-feeding women
* Uncontrolled and significant medical illness
* Vertebrobasilar or hemiplegic migraine according to the International Headache Society diagnostic criteria
* Having intracranial metal implants or a cardiac pacemaker
* A history of epilepsy or other organic brain disorders
* A history of psychological diseases
* Having changed medications for migraine within 1 month before giving us informed consent
* Drug abuser or alcoholics

**Maximum Age:** 70 Years

**Minimum Age:** 17 Years

**Sex:** ALL

**Standard Ages:**

- CHILD

- ADULT

- OLDER_ADULT

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Seoul

**Country:** Korea, Republic of

**Facility:** Seoul National University Hospital

**Zip:** 110-744

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000051270

- Term: Headache Disorders, Primary

- ID: D000020773

- Term: Headache Disorders

- ID: D000001927

- Term: Brain Diseases

- ID: D000002493

- Term: Central Nervous System Diseases

- ID: D000009422

- Term: Nervous System Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC10

- Name: Nervous System Diseases

- Abbrev: All

- Name: All Conditions

- Abbrev: BC23

- Name: Symptoms and General Pathology

- Abbrev: Rare

- Name: Rare Diseases

### Condition Browse Module - Browse Leaves

- ID: M11852

- Name: Migraine Disorders

- Relevance: HIGH

- As Found: Migraine

- ID: M9351

- Name: Headache

- Relevance: LOW

- As Found: Unknown

- ID: M22529

- Name: Headache Disorders

- Relevance: LOW

- As Found: Unknown

- ID: M26657

- Name: Headache Disorders, Primary

- Relevance: LOW

- As Found: Unknown

- ID: M5204

- Name: Brain Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M5742

- Name: Central Nervous System Diseases

- Relevance: LOW

- As Found: Unknown

- ID: T170

- Name: Acute Graft Versus Host Disease

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000008881

- Term: Migraine Disorders

### Misc Info Module

- Version Holder: 2024-05-24
