## Protocol Section
### Identification Module
**NCT ID:** NCT03626779

**Brief Title:** Bone Density in Immediate Implant Placment and Loading(BDIIPL)

**Official Title:** Prf Controlled,Randamized Cinical Trial of EFFECTS OF THE PLATELET-RICH FIBRIN (PRF) ON BONE DENSITY IN IMMEDIATE IMPLANT PLACEMENT AND LOADING IN ESTHETIC ZONE

#### Organization Study ID Info
**ID:** Cairo U
#### Organization
**Class:** OTHER
**Full Name:** Cairo University
### Status Module
#### Completion Date
**Date:** 2019-08-30

**Type:** ESTIMATED

#### Expanded Access Info
**Last Known Status:** NOT_YET_RECRUITING
#### Last Update Post Date
**Date:** 2018-08-22

**Type:** ACTUAL

**Last Update Submit Date:** 2018-08-21

**Overall Status:** UNKNOWN

#### Primary Completion Date
**Date:** 2019-08-30

**Type:** ESTIMATED

#### Start Date
**Date:** 2018-09-01

**Type:** ESTIMATED

**Status Verified Date:** 2018-08

#### Study First Post Date
**Date:** 2018-08-13
**Type:** ACTUAL
**Study First Submit Date:** 2018-07-30
**Study First Submit QC Date:** 2018-08-09
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** Ahmed adel shaaban

#### Responsible Party

**Investigator Affiliation:** Cairo University

**Investigator Full Name:** Ahmed adel shaaban

**Investigator Title:** CairoU

**Type:** SPONSOR_INVESTIGATOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** Atrumatic extraction ,immediate implant placment , prf as plug,immediate loading , mesure bone density 0-3-6-9 month

**Detailed Description:** Atrumatic extraction unrestorable tooth in esthetic zone and immediate implant placment and withdrow 10cc blood sample to gain prf plug as membrane and immediate provisional for one week and final restoration after 1 week , and mesure bone density from 0-3-6-9 month

### Conditions Module

**Conditions:**

- Bone Density Increased

### Design Module

#### Design Info

**Allocation:** RANDOMIZED

**Intervention Model:** PARALLEL

##### Masking Info

**Masking:** SINGLE

**Who Masked:**

- INVESTIGATOR

**Primary Purpose:** TREATMENT

#### Enrollment Info

**Count:** 10

**Type:** ESTIMATED

**Phases:**

- NA

**Study Type:** INTERVENTIONAL

### Arms Interventions Module

#### Arm Group 1

**Description:** Immediat placment and loading with prf

**Intervention Names:**

- Other: Prf

**Label:** immediate placment and loading with prf

**Type:** OTHER

#### Arm Group 2

**Description:** Immediate implant placment and loading without prf

**Label:** immediate implant placment and loading

**Type:** NO_INTERVENTION

### Interventions

#### Intervention 1

**Arm Group Labels:**

- immediate placment and loading with prf

**Description:** Take 10cc blood from patient and gain prf blug

**Name:** Prf

**Type:** OTHER

### Outcomes Module

#### Primary Outcomes

**Description:** Cbct

**Measure:** Bone density enhancement with prf in immediate implant placment and loding

**Time Frame:** 9 month

### Eligibility Module

**Eligibility Criteria:** Inclusion criteria:

* unrestorable anterior tooth.
* Good oral hygine
* Adequate bone hieght apical to the alveolus of failing tooth to ensure primary stability .

Exclusion Criteria:

* systematic disease which affect osteointgration.
* Bad oral hygiene
* Broxism, clenching, deep bite, edge to edge and abnormal habits.
* Non-treated peeiodontal diseases.
* Pregnancy and smokers. Severe infection. Loss of labial crest after extraction of failing tooth.

**Healthy Volunteers:** True

**Maximum Age:** 45 Years

**Minimum Age:** 20 Years

**Sex:** ALL

**Standard Ages:**

- ADULT

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000010009

- Term: Osteochondrodysplasias

- ID: D000001848

- Term: Bone Diseases, Developmental

- ID: D000001847

- Term: Bone Diseases

- ID: D000009140

- Term: Musculoskeletal Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC05

- Name: Musculoskeletal Diseases

- Abbrev: All

- Name: All Conditions

- Abbrev: BC16

- Name: Diseases and Abnormalities at or Before Birth

- Abbrev: BC17

- Name: Skin and Connective Tissue Diseases

- Abbrev: BC18

- Name: Nutritional and Metabolic Diseases

- Abbrev: Rare

- Name: Rare Diseases

### Condition Browse Module - Browse Leaves

- ID: M12949

- Name: Osteosclerosis

- Relevance: HIGH

- As Found: Bone Density Increased

- ID: M12932

- Name: Osteochondrodysplasias

- Relevance: LOW

- As Found: Unknown

- ID: M12043

- Name: Mucopolysaccharidosis IV

- Relevance: LOW

- As Found: Unknown

- ID: M5126

- Name: Bone Diseases

- Relevance: LOW

- As Found: Unknown

- ID: M5127

- Name: Bone Diseases, Developmental

- Relevance: LOW

- As Found: Unknown

- ID: M12097

- Name: Musculoskeletal Diseases

- Relevance: LOW

- As Found: Unknown

- ID: T3909

- Name: Mucopolysaccharidosis Type IV

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000010026

- Term: Osteosclerosis

### Misc Info Module

- Version Holder: 2024-05-24
