## Protocol Section
### Identification Module
**NCT ID:** NCT02667379

**Brief Title:** Skin Tests in Cat Allergic Patients With Cat Dander Samples Obtained Before and After Vaccinating the Cat

**Official Title:** Evaluation of Skin Prick Tests in Cat Allergic Patients With Cat Dander Samples Obtained Before and After Vaccinating the Cat

#### Organization Study ID Info
**ID:** ZU-HypoCat-001
#### Organization
**Class:** OTHER
**Full Name:** University of Zurich
### Status Module
#### Completion Date
**Date:** 2016-05

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2016-05-09

**Type:** ESTIMATED

**Last Update Submit Date:** 2016-05-06

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2016-05

**Type:** ACTUAL

#### Start Date
**Date:** 2016-02

**Status Verified Date:** 2016-05

#### Study First Post Date
**Date:** 2016-01-28
**Type:** ESTIMATED
**Study First Submit Date:** 2016-01-20
**Study First Submit QC Date:** 2016-01-25
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** University of Zurich

#### Responsible Party

**Type:** SPONSOR

### Oversight Module

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** Determination of allergenicity of cat dander samples obtained before and after vaccinating the cat

### Conditions Module

**Conditions:**

- Hypersensitivity

**Keywords:**

- Cat

- allergy

- dander

- Fel d 1

- Felis domesticus

### Design Module

#### Design Info

**Allocation:** NA

**Intervention Model:** SINGLE_GROUP

##### Masking Info

**Masking:** NONE

**Primary Purpose:** BASIC_SCIENCE

#### Enrollment Info

**Count:** 7

**Type:** ACTUAL

**Phases:**

- NA

**Study Type:** INTERVENTIONAL

### Arms Interventions Module

#### Arm Group 1

**Description:** Diagnostic skin testing with cat dander samples on volar forearms.

**Intervention Names:**

- Other: Diagnostic skin testing

**Label:** Diagnostic skin testing

**Type:** OTHER

### Interventions

#### Intervention 1

**Arm Group Labels:**

- Diagnostic skin testing

**Description:** 14 Skin prick tests on each volar forearm with cat dander samples.

**Name:** Diagnostic skin testing

**Type:** OTHER

### Outcomes Module

#### Primary Outcomes

**Description:** The primary variable will be the wheal size area of the immediate phase reaction in mm² measured after 15 minutes. Determination of the concentration threshold at which no more skin reactivity can be observed.

**Measure:** Wheal size of allergic skin reaction in mm² measured 15 minutes after application of test substance

**Time Frame:** 15 minutes

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* Informed Consent as documented by signature (Appendix Informed Consent Form)
* Male or female between 18 years to 65 years
* Confirmed cat allergy (positive skin prick test)

Exclusion Criteria:

* Diseases or medications, influencing the skin tests or impairing the correct conduct and evaluation of the study
* History of anaphylactic reaction
* Pregnancy
* Skin irritations in test area
* Participation in another clinical trial within the last 30 days and during the present study

**Maximum Age:** 65 Years

**Minimum Age:** 18 Years

**Sex:** ALL

**Standard Ages:**

- ADULT

- OLDER_ADULT

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Zurich

**Country:** Switzerland

**Facility:** University Hospital Zurich, Dept of Dermatology

**State:** ZH

**Zip:** 8091

#### Overall Officials

**Official 1:**

**Affiliation:** University Hospital Zurich, Dept Dermatology

**Name:** Thomas Kuendig, MD

**Role:** PRINCIPAL_INVESTIGATOR

### IPD Sharing Statement Module

**IPD Sharing:** NO

## Derived Section

### Condition Browse Module - Ancestors

- ID: D000007154

- Term: Immune System Diseases

### Condition Browse Module - Browse Branches

- Abbrev: BC20

- Name: Immune System Diseases

- Abbrev: All

- Name: All Conditions

### Condition Browse Module - Browse Leaves

- ID: M10018

- Name: Hypersensitivity

- Relevance: HIGH

- As Found: Hypersensitivity

- ID: M10200

- Name: Immune System Diseases

- Relevance: LOW

- As Found: Unknown

### Condition Browse Module - Meshes

- ID: D000006967

- Term: Hypersensitivity

### Misc Info Module

- Version Holder: 2024-05-24
