## Protocol Section
### Identification Module
**NCT ID:** NCT04075279

**Brief Title:** Heart at Work Study

**Official Title:** Cardiovascular Mechanisms of the Occupational Physical Activity Health Paradox: 24-hour Physical Activity, Blood Pressure, and Heart Rate

#### Organization Study ID Info
**ID:** STUDY19050097
#### Organization
**Class:** OTHER
**Full Name:** University of Pittsburgh
### Status Module
#### Completion Date
**Date:** 2020-07-24

**Type:** ACTUAL

#### Expanded Access Info
#### Last Update Post Date
**Date:** 2021-05-03

**Type:** ACTUAL

**Last Update Submit Date:** 2021-04-06

**Overall Status:** COMPLETED

#### Primary Completion Date
**Date:** 2020-04-20

**Type:** ACTUAL

#### Results First Post Date
**Date:** 2021-05-03

**Type:** ACTUAL

**Results First Submit Date:** 2021-04-06

**Results First Submit QC Date:** 2021-04-06

#### Start Date
**Date:** 2019-10-17

**Type:** ACTUAL

**Status Verified Date:** 2021-04

#### Study First Post Date
**Date:** 2019-08-30
**Type:** ACTUAL
**Study First Submit Date:** 2019-08-28
**Study First Submit QC Date:** 2019-08-29
### Sponsor Collaborators Module

#### Lead Sponsor

**Class:** OTHER

**Name:** University of Pittsburgh

#### Responsible Party

**Investigator Affiliation:** University of Pittsburgh

**Investigator Full Name:** Tyler Quinn

**Investigator Title:** Principle Investigator

**Type:** PRINCIPAL_INVESTIGATOR

### Oversight Module

**Is FDA Regulated Device:** False

**Is FDA Regulated Drug:** False

**Oversight Has DMC:** False

### Description Module

**Brief Summary:** This is an observational study to examine the cardiovascular mechanisms of increased cardiovascular mortality in those with high activity occupations.

**Detailed Description:** The current proposal uses a repeated-measures, within-subject design to address our aims. Twenty male participants will report to the laboratory to provide informed consent, complete baseline assessments, and receive ambulatory monitors. Following this session, each participant will wear physical activity and ambulatory cardiovascular monitors for 7 days, including at least one non-work day and one work day. Characterization of work activity will use physical activity data from self-reported time at work (Specific Aim I). The 24-hour cardiovascular load (HR and BP) and nocturnal HRV will be compared across work and non-work days (Specific Aim II). Lastly, whether fitness level or job strain modify the difference in cardiovascular strain between work vs. non-work days will be evaluated (Specific Aim III).

### Conditions Module

**Conditions:**

- Occupational Diseases

- Cardiovascular Diseases

- Cardiovascular Risk Factor

- Occupational Exposure

### Design Module

#### Design Info

**Observational Model:** CASE_CROSSOVER

**Time Perspective:** CROSS_SECTIONAL

#### Enrollment Info

**Count:** 19

**Type:** ACTUAL

**Study Type:** OBSERVATIONAL

### Outcomes Module

#### Primary Outcomes

**Description:** We will calculate the average heart rate over each 24 hour period throughout a one week monitoring period.

**Measure:** 24-hour Heart Rate

**Time Frame:** 24 hours

#### Secondary Outcomes

**Description:** We will calculate the average systolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).

**Measure:** 24-hour Ambulatory Systolic Blood Pressure

**Time Frame:** 24 hours

**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is root mean square successive differences (RMSSD).

**Measure:** Nocturnal Heart Rate Variability, RMSSD

**Time Frame:** approximately 8 hours (sleep time)

**Description:** This physical activity metric of steps per day was calculated as average number of steps during each day type (work versus non-workdays) throughout one week

**Measure:** Physical Activity Pattern. Steps Per Day

**Time Frame:** 1 week

**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is standard deviation of the normal to normal RR intervals (SDNN).

**Measure:** Nocturnal Heart Rate Variability, SDNN

**Time Frame:** approximately 8 hours (sleep time)

**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is low frequency power (LF).

**Measure:** Nocturnal Heart Rate Variability, LF

**Time Frame:** approximately 8 hours (sleep time)

**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is high frequency power (HF).

**Measure:** Nocturnal Heart Rate Variability, HF

**Time Frame:** approximately 8 hours (sleep time)

**Description:** This physical activity metric of minutes of moderate to vigorous physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week

**Measure:** Physical Activity Pattern. MVPA

**Time Frame:** 1 week

**Description:** This physical activity metric of minutes of light physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week

**Measure:** Physical Activity Pattern. LPA

**Time Frame:** 1 week

**Description:** This physical activity metric of minutes of sedentary time was calculated as average minutes during each day type (work versus non-workdays) throughout one week

**Measure:** Physical Activity Pattern. Sedentary

**Time Frame:** 1 week

**Description:** This physical activity metric of minutes of upright time was calculated as average minutes during each day type (work versus non-workdays) throughout one week

**Measure:** Physical Activity Pattern. Upright

**Time Frame:** 1 week

**Description:** We will calculate the average diastolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).

**Measure:** 24-hour Ambulatory Diastolic Blood Pressure

**Time Frame:** 24 hours

### Eligibility Module

**Eligibility Criteria:** Inclusion Criteria:

* middle age (35-59 years)
* male
* self-report working full-time in the food service industry (≥30 hours/week)
* self-report predominantly completing light intensity activity job responsibilities (≥75% work time walking, light movement, or standing)

Exclusion Criteria:

* Resting blood pressure of ≥150 mmHg systolic and/or ≥95 mmHg diastolic
* currently taking medications that are known to affect blood pressure or heart rate (e.g. Beta-blockers, ACE inhibitors, etc.)
* greater than low risk to participate in physical activity as determined by PAR-Q (answer of yes to any of the 7 physical activity readiness questionnaire questions)
* report working a second job in addition to their primary full-time job
* report working overnight shifts (10pm-6am)
* reported physical dysfunction (inability to walk 2 city blocks or climb 2 flights of stairs)
* inability to complete the sub-maximal exercise test to completion (80% age-predicted heart rate maximum)
* Currently being treated for a serious medical condition such as kidney disease, liver disease, cancer, or heart disease.

**Gender Based:** True

**Gender Description:** Only males are eligible for this study.

**Maximum Age:** 59 Years

**Minimum Age:** 35 Years

**Sampling Method:** NON_PROBABILITY_SAMPLE

**Sex:** MALE

**Standard Ages:**

- ADULT

**Study Population:** Middle-aged male food service workers

### Contacts Locations Module

#### Locations

**Location 1:**

**City:** Pittsburgh

**Country:** United States

**Facility:** Physical Activity and Weight Management Research Laboratory

**State:** Pennsylvania

**Zip:** 15261

#### Overall Officials

**Official 1:**

**Affiliation:** Graduate Student

**Name:** Tyler D Quinn, MS

**Role:** PRINCIPAL_INVESTIGATOR

### IPD Sharing Statement Module

**Description:** Upon completion of all data collection, data will be analyzed and summary conclusions will be published in a peer reviewed scientific journal.

**IPD Sharing:** NO

## Document Section

### Large Document Module

#### Large Docs

- Date: 2019-09-26

- Filename: Prot_SAP_ICF_000.pdf

- Has ICF: True

- Has Protocol: True

- Has SAP: True

- Label: Study Protocol, Statistical Analysis Plan, and Informed Consent Form

- Size: 21377333

- Type Abbrev: Prot_SAP_ICF

- Upload Date: 2021-04-06T08:09

## Derived Section

### Condition Browse Module - Browse Branches

- Abbrev: BC24

- Name: Occupational Diseases

- Abbrev: All

- Name: All Conditions

### Condition Browse Module - Browse Leaves

- ID: M12719

- Name: Occupational Diseases

- Relevance: HIGH

- As Found: Occupational Diseases

### Condition Browse Module - Meshes

- ID: D000002318

- Term: Cardiovascular Diseases

- ID: D000009784

- Term: Occupational Diseases

### Misc Info Module

- Version Holder: 2024-05-24

## Results Section

### Adverse Events Module

#### Event Groups

**Group ID:** EG000

**Title:** Research Study Participation

**Deaths Num At Risk:** 19

**Description:** Participants who were enrolled in the study and completed all study procedures.

**ID:** EG000

**Other Num at Risk:** 19

**Serious Number At Risk:** 19

**Title:** Research Study Participation

**Frequency Threshold:** 0

**Time Frame:** 1 week

## Results Section - Baseline Characteristics Module

### Denomination Counts

**Group ID:** BG000

**Value:** 19

**Units:** Participants

### Group

**ID:** BG000

**Title:** Research Study Participation

**Description:** Participants who were enrolled in the study and completed all study procedures.

### Measure

#### Measurement

**Group ID:** BG000

**Spread:** 7.9

**Value:** 46.6

**Class Title:** 

### Measure

#### Measurement

**Group ID:** BG000

**Value:** 0

**Category Title:** Female

#### Measurement

**Group ID:** BG000

**Value:** 19

**Category Title:** Male

**Class Title:** 

### Measure

#### Measurement

**Group ID:** BG000

**Value:** 0

**Category Title:** American Indian or Alaska Native

#### Measurement

**Group ID:** BG000

**Value:** 0

**Category Title:** Asian

#### Measurement

**Group ID:** BG000

**Value:** 0

**Category Title:** Native Hawaiian or Other Pacific Islander

#### Measurement

**Group ID:** BG000

**Value:** 4

**Category Title:** Black or African American

#### Measurement

**Group ID:** BG000

**Value:** 13

**Category Title:** White

#### Measurement

**Group ID:** BG000

**Value:** 2

**Category Title:** More than one race

#### Measurement

**Group ID:** BG000

**Value:** 0

**Category Title:** Unknown or Not Reported

**Class Title:** 

### Measure

#### Measurement

**Group ID:** BG000

**Value:** 19

**Class Title:** United States

### Measure

#### Measurement

**Group ID:** BG000

**Value:** 8

**Category Title:** Food Service

#### Measurement

**Group ID:** BG000

**Value:** 9

**Category Title:** Material Moving

#### Measurement

**Group ID:** BG000

**Value:** 1

**Category Title:** Healthcare

#### Measurement

**Group ID:** BG000

**Value:** 1

**Category Title:** Building and Grounds Maintenance

**Class Title:** 

**Denomination Units Selected:** 

## Results Section - Baseline Characteristics Module

### Measure 1
**Dispersion Type:** STANDARD_DEVIATION
**Parameter Type:** MEAN
**Title:** Age, Continuous
**Unit of Measure:** years
### Measure 2
**Parameter Type:** COUNT_OF_PARTICIPANTS
**Title:** Sex: Female, Male
**Unit of Measure:** Participants
### Measure 3
**Parameter Type:** COUNT_OF_PARTICIPANTS
**Title:** Race (NIH/OMB)
**Unit of Measure:** Participants
### Measure 4
**Parameter Type:** NUMBER
**Title:** Region of Enrollment
**Unit of Measure:** participants
### Measure 5
**Parameter Type:** COUNT_OF_PARTICIPANTS
**Title:** Occupational Industry
**Unit of Measure:** Participants
## Results Section - More Information Module
### Certain Agreement
### Point of Contact
**Email:** yhh7@cdc.gov
**Organization:** Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health
**Phone:** 412-386-4450
**Title:** Dr. Tyler Quinn
## Results Section - Outcome Measures Module
### Outcome Measure 1
### Outcome Measure 2
### Outcome Measure 3
### Outcome Measure 4
### Outcome Measure 5
### Outcome Measure 6
### Outcome Measure 7
### Outcome Measure 8
### Outcome Measure 9
### Outcome Measure 10
### Outcome Measure 11
### Outcome Measure 12
## Results Section
### Outcome Measures Module
#### Outcome Measure 1
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 1.2
- **Upper Limit:** 
- **Value:** 83.8
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 1.4
- **Upper Limit:** 
- **Value:** 78.5
**Title:** 
#### Outcome Measure 2
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 1.7
- **Upper Limit:** 
- **Value:** 126.0
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 1.8
- **Upper Limit:** 
- **Value:** 124.0
**Title:** 
#### Outcome Measure 3
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 4.04
- **Upper Limit:** 
- **Value:** 34.17
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 4.32
- **Upper Limit:** 
- **Value:** 35.34
**Title:** 
#### Outcome Measure 4
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 945
- **Upper Limit:** 
- **Value:** 12,772
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 1,063
- **Upper Limit:** 
- **Value:** 7,923
**Title:** 
#### Outcome Measure 5
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 3.48
- **Upper Limit:** 
- **Value:** 39.85
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 3.71
- **Upper Limit:** 
- **Value:** 42.14
**Title:** 
#### Outcome Measure 6
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 0.20
- **Upper Limit:** 
- **Value:** 6.18
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 0.21
- **Upper Limit:** 
- **Value:** 6.45
**Title:** 
#### Outcome Measure 7
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 0.30
- **Upper Limit:** 
- **Value:** 5.22
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 0.31
- **Upper Limit:** 
- **Value:** 5.56
**Title:** 
#### Outcome Measure 8
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 7.2
- **Upper Limit:** 
- **Value:** 72.4
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 8.9
- **Upper Limit:** 
- **Value:** 41.5
**Title:** 
#### Outcome Measure 9
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 19.9
- **Upper Limit:** 
- **Value:** 391.5
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 23.3
- **Upper Limit:** 
- **Value:** 285.2
**Title:** 
#### Outcome Measure 10
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 18.4
- **Upper Limit:** 
- **Value:** 492.5
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 22.5
- **Upper Limit:** 
- **Value:** 629.7
**Title:** 
#### Outcome Measure 11
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 18.4
- **Upper Limit:** 
- **Value:** 462.4
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 22.5
- **Upper Limit:** 
- **Value:** 325.2
**Title:** 
#### Outcome Measure 12
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 1.0
- **Upper Limit:** 
- **Value:** 75.2
**Title:** 
**Class:**
##### Category
**Measurements:**
- **Comment:** 
- **Group ID:** OG000
- **Lower Limit:** 
- **Spread:** 1.1
- **Upper Limit:** 
- **Value:** 72.6
**Title:** 
## Results Section
### Outcome Measures Module
#### Outcome Measure 1
**Description:** We will calculate the average heart rate over each 24 hour period throughout a one week monitoring period.
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 24 hours
**Title:** 24-hour Heart Rate
**Type:** PRIMARY
**Unit of Measure:** beats per minute
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 2
**Description:** We will calculate the average systolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 24 hours
**Title:** 24-hour Ambulatory Systolic Blood Pressure
**Type:** SECONDARY
**Unit of Measure:** millimeters of Mercury
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 3
**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is root mean square successive differences (RMSSD).
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** approximately 8 hours (sleep time)
**Title:** Nocturnal Heart Rate Variability, RMSSD
**Type:** SECONDARY
**Unit of Measure:** milliseconds
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 4
**Description:** This physical activity metric of steps per day was calculated as average number of steps during each day type (work versus non-workdays) throughout one week
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 1 week
**Title:** Physical Activity Pattern. Steps Per Day
**Type:** SECONDARY
**Unit of Measure:** steps per day
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 5
**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is standard deviation of the normal to normal RR intervals (SDNN).
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** approximately 8 hours (sleep time)
**Title:** Nocturnal Heart Rate Variability, SDNN
**Type:** SECONDARY
**Unit of Measure:** milliseconds
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 6
**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is low frequency power (LF).
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** approximately 8 hours (sleep time)
**Title:** Nocturnal Heart Rate Variability, LF
**Type:** SECONDARY
**Unit of Measure:** log milliseconds
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 7
**Description:** We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is high frequency power (HF).
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** approximately 8 hours (sleep time)
**Title:** Nocturnal Heart Rate Variability, HF
**Type:** SECONDARY
**Unit of Measure:** log milliseconds
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 8
**Description:** This physical activity metric of minutes of moderate to vigorous physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 1 week
**Title:** Physical Activity Pattern. MVPA
**Type:** SECONDARY
**Unit of Measure:** minutes per day
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 9
**Description:** This physical activity metric of minutes of light physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 1 week
**Title:** Physical Activity Pattern. LPA
**Type:** SECONDARY
**Unit of Measure:** minutes per day
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 10
**Description:** This physical activity metric of minutes of sedentary time was calculated as average minutes during each day type (work versus non-workdays) throughout one week
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 1 week
**Title:** Physical Activity Pattern. Sedentary
**Type:** SECONDARY
**Unit of Measure:** minutes per day
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 11
**Description:** This physical activity metric of minutes of upright time was calculated as average minutes during each day type (work versus non-workdays) throughout one week
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 1 week
**Title:** Physical Activity Pattern. Upright
**Type:** SECONDARY
**Unit of Measure:** minutes per day
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
#### Outcome Measure 12
**Description:** We will calculate the average diastolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).
**Dispersion Type:** Standard Error
**Parameter Type:** LEAST_SQUARES_MEAN
**Reporting Status:** POSTED
**Time Frame:** 24 hours
**Title:** 24-hour Ambulatory Diastolic Blood Pressure
**Type:** SECONDARY
**Unit of Measure:** millimeters of Mercury
##### Group
**Description:** Participants who were enrolled in the study and completed all study procedures.
**ID:** OG000
**Title:** Research Study Participation
### Participant Flow Module
#### Group
**Description:** All participants were enrolled into a single arm and all comparisons were made within subjects.
**ID:** FG000
**Title:** Middle-aged Males in High Activity Occupations
#### Period
**Title:** Overall Study
##### Milestone
**Type:** STARTED
###### Achievement
**Group ID:** FG000
**Number of Subjects:** 19
##### Milestone
**Type:** COMPLETED
###### Achievement
**Group ID:** FG000
**Number of Subjects:** 19
##### Milestone
**Type:** NOT COMPLETED
###### Achievement
**Group ID:** FG000
**Number of Subjects:** 0
**Has Results:** True