where are cpg islands clustered in mammalian genomes?
Because of this, the presence of a CpG island is used to help in the prediction and annotation of genes. In mammalian genomes, CpG islands are typically 300-3,000 base pairs in length, and have been found in or near approximately 40% of promoters of mammalian genes. About 70% of human promoters have a high CpG content.