what subatomic particle make up most of the mass in an atom?
Protons and neutrons are responsible for most of the atomic mass e.g in a 150 person 149 lbs, 15 oz are protons and neutrons while only 1 oz. is electrons. The mass of an electron is very small (9.108 X 10-28 grams). Both the protons and neutrons reside in the nucleus.