what causes high protein creatinine ratio?
urine protein:creatinine ratios >45 mg/mmol (2) Causes of persistent proteinuria include: primary renal disease: this may be glomerular (e.g. glomerulonephritis) or tubular. secondary renal disease: diabetes mellitus, hypertension, connective tissue diseases, vasculitis, amyloidosis, myeloma, congestive cardiac failure.