what will really irk you is what if souls get destroyed or enslaved in the after-life, if you're lucky enough to even be reincarnated.  aside from being completely destroyed (probably the worst fate for a soul), can you imagine for example, being enslaved as a soul to perform after-life labour for the next 5000 years? or what if its like in hellsing (souls can be absorbed by vamps) ? then there is of course the more orthodox beliefs in heaven and hell, but once again this is all sort of a hazy subject for humanity because we don't fully understand the after-life or what happens, besides whats been told by religion and ndes (near death experiences).
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