line-1 retrotransposition is present in all cells when certain stressors are present, and hela cells have to be derived from lineages that feature it so they can "act like cancer cells hurr durrr", you're doing a shit job at discrediting that study. it's now clear as day to me you don't have interest in sincerity you kike   es/pmc5070806/2. materials2.1 cell culture medium and transfection reagents two clonal hela cell lines support retrotransposition. hela-jvm cells are used to assay line-1 retrotransposition (24). hela-ha are used to assay either line-1 or alu retrotransposition (72).   593-024-01650-2 retrotransposons are mobile dna sequences duplicated via transcription and reverse transcription of an rna intermediate.cis-regulatory elements encoded by retrotransposons can also promote the transcription of adjacent genes. somatic line-1 (l1) retrotransposon insertions have been detected in mammalian neurons. it is, however, unclear whether l1 sequences are mobile in only some neuronal lineages or therein promote neurodevelopmental gene expression. here we report programmed l1 activation by sox6, a transcription factor critical for parvalbumin (pv) interneuron development.
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