that's really sad she is basically done. worst is that there is probably nothing that could revert this if she is that far she is probably long gone.  people changed after vax and personally sadly i had to cut few of them from my life and im afraid that i will be left eventually with 3-4 people that didn't vaxxed because i was pushing on them daily to not do so. luckily at least those 3 friends didn't do it others are far beyond and gone if it gets any worse i will have to leave from here actually which is fucked up.
Slovakia