 Bought the 4runner when it had 70k miles on it.  Have done a lot of long distance driving and now have 397k on the suv.  Have only done normal maintenance.  No valve jobs or other major procedures.  Recently replaced igniter, plugs, and fuel injectors and it runs good as ever.  Had Michelin LTX tires on it and got 150k miles on one set.  This is an amazing vehicle and is built to last.  I  am sure I can get  to 500k miles.  Engine is not overly powerful but not a big issue.  You can also chew through brake rotors quickly if  you are heavy on the brake.  Overall I love this suv.