 While you would expect most mid-size sedans to hit the 100K mile mark before even thinking of having any maintenance issues, with a Nissan, who rate themselves as high or even above Honda and Toyota in quality and reliability, you should expect 150-200k before experiencing problems. I've had several problems with mine since I bought it, and while I have owned it for over 6 years, I've had to do far more than the regular oil and brake changes and basic upkeep of a vehicle. Front axle, wheel bearings, motor mounts, power steering, electronics, you name it; I've had to put a lot of extra money into it to keep it running well, and it still hasn't hit the 107k mile mark. I love the acceleration and power you get from the Altima, but I'm ready to get rid of it and try something else - it's turning into a money pit far sooner than it should. Sure there may be Altima's out there with 200K and not a problem, but that wasn't my experience, and it has definitely soured me on ever purchasing a Nissan again.