 We just bought the new 4Matic E350 and it is AWESOME.  The fit and finish of the car is just terrific.  Acceleration is MUCH better than the BMW 545 and anything Lexus offers in this price range.  The steering is incredible.  On the interior, the COMAND control knob is very nice, once you get used to it.  Some other good features are the backup camera and the integrated bluetooth.   We love this car - it seems as though it should be a lot more expensive than the $61K we paid for it.  