 We purchased a 2006 Highlander to replace our 2000 Blazer.  We chose to go with the Highlander because we wanted improved fuel economy, but still with a V6/4WD combination.  We also were impressed with the safety ratings on the Highlander.  Now, the Blazer was OUTSTANDING in the snow, and only time will tell if the Highlander will do well in the snow too.  The power delivery from the V6 was better than I expected, but having also test-driven a 2008 model (expensive) it lags in comparison.  The transmission is seamlessly smooth, and the suspension in the Sport package makes the vehicle more fun to drive.  The third row really only provides adequate room for children, but it is nice to have.