Can i run GTA Vice City on Android-x86 PC? Recently i have installed Android-x86 on my Lenovo laptop and i want to install and play GTA vice city there. My OS in android 4.4.2. 4 GB ram and 3 GB swap memory 2.4 Ghz quadcore intel i3 processor and nvidia 1 GB video card
Depends. It may have some graphical issues considering drivers and probably a few other compatibility problems. The most major spike is the drivers here. If they work and are compatible with game, your game will run. Else it wont (I suspect graphical glitches). Honestly, its almost impossible to judge like that with just that much information provided so that leaves you with only ability to try it and see if it works.

But that aside, how do you plan on playing it? Even if you have/had touch screen I can barely imagine how its possible to play it.

Bottomline-> You can test it. Although I do have doubts in mind that you will be able to play it (not only due to hardware and drivers, but also due to control mechanics).