How can I stop the Skype notifications from re-enabling? I have Skype on my Moto G, but I don't use it much. It's primarily for contacting cow-orkers at work. I certainly don't want to get notified every time anyone says one in a group chat while I'm on my day off.

So I switched off the notifications by selecting "block all" in the notification settings for the app. Then I got a notification. So I switched off the notifications again. Then I got a notification. So I switched off the notifications yet again. Then... you get the picture.

How can I keep the notifications from Skype switched off?

Or do I just have to uninstall it?
Skype running in background annoys me so much that I keep it signed OUT when not using.
To turn of notifications of SKype on Android :
Tap the menu icon (three vertical lines), tap Settings > Notifications, then tap Notifications to turn them off.

what you have been doing is , you were telling your android to mute the notifications its better to tell the app itself