Will I loose manufacturer updates if I root my phone I have ASUS Zenfone 2 Laser with Marshmallow but I want to root my phone fot certain reasons but don't want to loose OTA updates from manufacturer. Please let me know if any work around is possible.
In most phones, especially the newer ones, you cannot receive OTA updates, since /system is modified by rooting and it fails the verification for OTA updates.
To better understand details about verification see answers to this question  What specifically prevents OTAs from being taken on modified /systems, and why can&#39;t it be shut off?

Systemless Root is an option to prevent this. In this method of rooting only the boot partition is modified, keeping /system intact. Prior to flashing OTA one needs to flash stock boot and recovery images to allow OTA updates . You can read more about systemless root in the answers here Systemless Root

Do ensure you research the linked XDA thread in answers and choose the right version for your device, based on user feedback