OTA update multiple times I am using Xiaomi mobile which is unrooted. In that I have installed developer ROM. The manufacturer releases weekly updates, which is twice in week. 

My question is that, Will it creates any software/hardware problems to the device after updating/installing several times.
"Will it creates any software/hardware problems to the device after updating/installing several times"
 - No.

These days, android security patches are being released every month. So, it is common to get monthly updates, although xiomi releases weekly updates. These updates are intended to fix the known issues and includes some security patches. For further information regarding the updates, you can refer to the update log, which is provided along with the update.