Does HTC Sync work well with Thunderbird? As I no longer have access to Outlook, I have to look for alternatives for managing mail, agenda's and contacts. 

My first guess would be Thunderbird, but I wonder how well this syncs with HTC Sync as I never had any trouble setting it up with Outlook, I would prefer that it stayed that way.

So does anyone have any experience with syncing their Android phone through Thunderbird?
I'd recommend, rather, using Thunderbird as an IMAP client with the Google Contacts and Lightning add-ons ( http://addons.mozilla.org/en-US/thunderbird/addon/7307 and http://mozilla.org/projects/calendar). You should be able to manage your contacts and calendar in Thunderbird and sync with Google. So then your Thunderbird and phone will each synchronize to and from Google.