Adjust a view so there is one image of size normal and other images are thumbnails I have created a gallery for every user. I would now like to alter the view so that one of the images is a medium size and the other images are thumb nail size. I know you can adjust the layout in a view but I am not sure how to change the size of one image and keep the others as the default thumbnail.
Check out the View Nodes Split module.

This module allows site administrators or builders to have a different view mode for the first nodes of a view result.
If you ever had (or currently have) this scenario: you have a view of nodes but you want that the first node (or first X nodes) to have a different view mode, then this module is for you. The module can split the results from a view into 2 lists. It actually does not make 2 separate lists, it just uses a a different view mode to render the first X nodes from a view.

You can also use a view attachment to display a node and attach more nodes to it. Make sure you offset your attached view by 1.