How to customize drupal node using 'PANELS' I am trying to implement the "PANELS" module in drupal 7.31 to customize a page display. 

Panels Module : 7.x-3.4

Drupal version : 7.31

I have created courses(as a product) using "COMMERCE" module. I am able to display the LIST Courses
using Panels. But I am also want to customize the course detail page(User click on course and then redirect to detail page).

You can see list of courses using Panels on here:



Now I want to customize the detail page where all details show from Database using Panels.

You can also see Course Detail page here:
You can't customize the node detail page with panels. You will have to use display suite. DS allows you to do a lot of things, and one of them is "Display Suite allows you to take full control over how your content is displayed using a drag and drop interface."

Hope this helps