Select Panel Node Layout on Node edit form I have multiple different layout variations all for the same node type, is it possible to select which one will be used from the node edit form?

For example I have a node type of product which has the following layout variations:


2 Column
3 Column
2 Column Hybrid


On the node edit for I would have then have a drop down (or something else) which allows me to select one of the variations listed above. Is this possible?
It sounds like you are using Panels (presumption based on the column names), so this is very easy to achieve. 

In Page Manager, enable and edit node_view. Create a new panel variant. Enable Selection Rules for the variant. Add the selection rules "node_type = product" and "field_layout = 2 column". 

Then carry on through the rest of the config, ie choose 2 column layout and put in your fields/blocks/etc. You will then have to create 2 more variants (or clone and edit the current variant), changing the selections rules and layout to suit.