Biological replicates on Chip-seq Transcription factor data I have 2 biological replicates for chip-seq transcription factor data and I have applied macs2 peak calling for each replicate separately. 

How can i make use of the biological replicates to extract the most out the data?

Thanks!
You could first look at the degree of correlation between the two replicates - what proportion of peaks are shared between the two, versus peaks found in one sample only?  This will give an idea of how repeatable the analysis is, and how many peaks are variable between samples or due to artefacts of the method.

When it comes to interpreting the biology behind the binding patterns, you are probably going to want to only interpret peaks which you find in both replicates.