Can structural - equation modeling be used in Bioinformatics? I am a bioinformatics student and I was learning the basics of structural equation modeling (SEM).

I was wondering, are there any applications of SEM on  bioinformatics? Are there any strong sides for use of structural equation models using data on bioinformatics?

I did a quick search and found almost nothing. While it seemed like a learning algorithm, I can't say I figured it out completely.
I have came across them in gene regulatory network analysis before. see here and here. However I haven't seen them in other contexts, but that's not to say they don't exist.