What tools can I use to look up my alleles, genotypes, or phenotypes from my sequenced DNA (WGS)? (I am not a Bioinformatics expert, please forgive and educate me if I've used any wrong terms or assumptions here)
I bought a &quot;Whole Genome Sequence&quot; kit, which gave me the following VCF files (this service did not include any analysis, just the raw data):
cnv.vcf
indel.vcf
snp.vcf
sv.vcf
My understanding is that these files show the differences of my DNA relative to a reference human genome (hg19 in my case)
What tools and resources can I use to find out which known alleles/variants of genes I have?
An example: Blood type
According to Wikipedia, there are 6 common alleles of the ABO gene, and which alleles I have determine my blood type.
Looking at my VCF results, I have these SNPs and INDELs within that gene:
&lt;removed&gt;

Given this, how would I figure out my blood type?
I understand that my data may not be 100% accurate, and that many phenotypes are the result of more than one gene, environmental factors, or are not well studied at all, but this should work for some simple things ie blood type, COMT, BHLHE41, CYP1A2, etc
If this is your own DNA and you are trying to analyse yourself you should talk to a genetic counselor. I personally think it's cool, but I deeply understand the potential consequences.
What you want is a variant annotation tool. There are many, but I normally write my own. Which is simply a case of pulling down a database and using pandas to match variants with annotation.
There are many databases. The biggest popular database is gnomad and the biggest disease database is clinvar. Others include omim, snpdb and 1k genomes. I'm not sure about blood sorry but I'm sure you can find one.