Standard Cutoff for Moderated T-statistics I'm looking at some microarray data. For the first time I've calculated a moderated T statistic from limma.

Is there any standard practice for where to cut off that value? For log2 fold change I usually cut off at +/- 1.5 and adjust accordingly; for adjusted p value I cut off at p&lt;0.01 and adjust accordingly. 

These moderated T statistics seem a little higher than log2 fold change and I'm not sure what is generally accepted as significant.

Thanks!
You're misinterpreting the moderated T-statistic, it's basically the fold-change divided by its variance. The p-value comes directly from that, so if you filter by moderated fold-change you're just setting an unknown (unless you go through the trouble of figuring it out) p-value threshold. Instead, do exactly as you've been doing and set appropriate (adjusted) p-value and fold-change thresholds.