Is it possible to save animation as frame by frame to edit? I'm pretty sure this is not a duplicate question been look for this for a month now. 

I'm planning to make animations with blender and heard of the grease pencil thing but I need to make 3d animations and edit them.

As in a basic frame rate even with 15fps a 10-20 minute animation would be 9000-18000 frames and to edit every single one would to save each and every frame individually. Is there a way to use the grease pencil with 3d animation or is there a way to actually save 18000 frames?

Somehow I managed a while ago to download a 4 hour video.(around 1.6gb)
Would that be the same as frame by frame or has it been compressed?
Blender does have the ability to render to individual frames (PNG format is popular) and this is the preferred workflow.



I like to increase the compression to 100%, and if you aren't rendering frames with transparency, then use RGB instead of RGBA.  And uncheck the Overwrite box.  If you decide you need to throw away the previously rendered frames (because you updated the animation or whatever) you can delete them using your file explorer or bash.

As you have calculated this can result numerous images, which are usually each pretty large.

When you say you intend to "edit" the results of blender's rendering, you are being pretty vague, and depending upon the nature of the alterations you want to perform, your workflow can vary drastically.