Blender 2.8 Custom Start Window (Ctrl + u) Not working Ctrl + U worked in 2.79 for me, but in 2.8 it doesn't seem to work. Even if I press ctrl + u after deleting the starting cube, the next time I open Blender it's still there. Is there another way to do this now?

Thank you so much for your time!
You will have to do this through the menu.

To save the default scene use File > Save Startup file.



Many shortcuts have changed in 2.8. There is no default shortcut for that operation any more. Ctrl+Alt+U doesn't work any more.