how to do custom animation in a mhx file made using Makehuman I have a human model made using Makehuman tool. I have exported it to Blender. As a beginner I found it very confusing. Could see lots of details.

Looking for some simple tutorial that helps learning animation from this file. I need to do animation of hand,face. 

This is for academic research.
You should read or watch a few of the available tutorials or 100 'best', the mhx addon adds buttons for the rig-layers where you can select which manipulators are shown in the viewport.
The following animation was recorded in Pose Mode. You should read about the difference between IK/FK.
After that just record your animation by keyframing the poses setup by the controls.