ESP32-CAM interfacing with CCS811+HDC1080+BMP280 I want to measure Temprature, Pressure, Humidity and CO2 in a room with ESP32-CAM &amp; CCS811+HDC1080+BMP280 

Since this module is combination of 3 sensors. Can I integrate it with ESP32-CAM over Software SPI ?
No. Those three devices are I2C devices, not SPI devices. 

Using that is no different to using three individual sensors all wired to the same I2C bus.