Arduino port recognition New Arduino Uno, Arduino 1.6.3, MBP running 10.10.5. 

The Arduino IDE is running, I connect to the laptop via usb. The green LED is on the amber light is on but it's not blinking. 

I attempted to upload the blink file from File>Example>Basic>Blink. It compiles without issue but won't upload. I get the can't open device "/dev/cu.usbmodem1421" : No such file or directory...

I have attempted using the reset button, changing ports, cycling the IDE and the computer. The killer is that I've had an Arduino on this laptop before. 

Any suggests for getting the Arduino linked and operational.
Sorry to dredge up an old thread (well, really only replying to one that got robo-dredged :), but maybe this will help someone someday.

A /dev/cu.&lt;something&gt; is a unix port designation. "cu." meant a port used for modems, back in the mists of time but probably isn't relevant today. But what we do learn from it is that the OP is probably using a Mac, and for sure, not Windows.

"/dev/cu.usbmodem1421" is a typical device name for an Arduino as seen by a Mac on a particular one of its USB ports - the numeric part varies according to which Mac USB port the Arduino is connected to each time.

Arduinos &amp; FTDI devices do not need additional drivers on Mac OS (that may not be true for other, non-FTDI USB-to-serial devices).

In this case, the OS already reports seeing (what looks like) an Arduino. The suggestion already put forward, checking the board-type and port selections in the IDE's 'Tools' menu, is the place to start.