I fried the AMS1117 voltage regulator on my Arduino Clone, is this the cause? I had the 12V DC power jack plugged-in all the time, and "to make things more exciting" I also plugged-in the "data" USB whenever I had a new sketch to upload. Is this combination a big no-no, or is my step-up converter to blame?

I am completely new to this stuff but now when thinking of it those 12V from the power jack + 5V from the "data" USB probably violate this clause:
If using more than 12V, the voltage regulator may overheat and damage the board.
The "problem" with the AMS1117 voltage regulator is the amount of current they can safely provide drops as the input voltage rises. I'm a Arduino noob, so I looked at the data sheet for the AMS1117 series of voltage regulators. There is a formula: PD=(VIN-VOUT)(IOUT) and Note 2: which says the maximum power dissipation for the SOT-223 package is 1.2 W.

The best case scenario is to use an input voltage of 6.5 volts. (6.5-5)(0.8)=1.2W. This gives you 0.8 amps maximum output. If you use a 12 volt power supply: (12-5)(0.1714)=1.2W. This only gives you 0.1714 amps maximum output.

I'm not sure what kind of power jack you are using, so I'll give you an example of one that I used in a project. It says input 120VAC, output 12VDC, 200ma. The problem is, it actually puts out 20VDC open circuit with no load.

The data sheet gives a maximum input voltage of 15 volts but that would only provide a maximum of 120 mA output.