How can one generate a vanity Bitcoin address with both a given prefix and suffix? I want generate a unique Bitcoin address with vanitygen that has both a given prefix and a given suffix: 
  1Bit******************Bit

How would I be able to achieve that?
Vanitygen has a regex option, for generating addresses that match an arbitrary regular expression.  I think that

vanitygen -r '^1Bit.*Bit$'

would work.

Note that it will not be able to estimate the expected time that would be required.