Largest block (measured in Bitcoins) What is the block in the blockchain with the most Bitcoins transacted?
I can't say that I'm certain of it, but this is the largest block I've ever seen:

00000000000000fb62bbadc0a9dcda556925b2d0c1ad8634253ac2e83ab8382f aka nr 153509

It has a total output volume of 607,176.29050282 BTC, primarily because of this 550k transaction.