Background information on warning, when closing wallet in pruned mode What are the implications and reasons behind this warning on gui popup, when closing the wallet:


  "bitcoin closing the wallet for too long can result in having to
  resync the entire chain if pruning is enabled"


A pruned node will always catch up, whats the hassle?
If you have a wallet that isn’t opened for the period of pruning, it won’t be able to scan transactions. If you set the limit to 2GB, and 4GB of blocks pass without opening the wallet, it may miss incoming transactions as the required blocks will have been deleted.