If I lose my wallet and private key does that effectively remove bitcoin from the market forever? If I lose my wallet and private key does that effectively remove bitcoin from the market forever?

I understand that if I lose my wallet and have no record of my private key then I won't be able to re-establish my wallet. Does this mean that effectively the content of the lost wallet is lost forever to myself and the market?
If you permanently loose your keys, the short answer is essentially yes. Your loss, a deflation, will cause the value Bitcoin being held by others to go up proportionately. 

With a 100% efficient quantum computer (not likely at all), the amount of energy required to brute force compute the private keys will cost ~$100M each in electricity (assuming 5 cents per KiloWatt-Hour) if the public keys associated with the private keys are published on the blockchain.