Tips for golfing in 2D languages What general tips do you have for golfing in 2 dimensional programming languages? I'm looking for tips which can be applied to code-golf problems and are  specific to 2D programming languages, but not specific to any one language (Responses like "remove comments" and "use the M operation" are not answers).

Please post one tip per answer.
Avoid horizontal gaps
Often, code will leave largs gaps of whitespace to the left hand side of the program, like so.
abc
  d
  e

This adds 4 bytes, when this could be avoided by left aligning.
cde
b
a

If you need to use large gaps of whitespace, try to make them vertical, instead of horizontal.
########
#      #
#      #
#      #

vs
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