PRNG output with truly random noise I am considering a situation where an adversary does not have access to the $n$-bit output string of a PRNG, but instead receives a noisy version of it, where each bit of the string is flipped with probability $p$. We assume that this noise which causes the bits to flip is truly random.

What can we say concretely about the difficulty of distinguishing this noisy PRNG output from a truly random string? Of course, for $p=0$ we recover the standard scenario for the PRNG and the problem is as hard as solving the underlying computational problem, and for $p=\frac12$ the string is truly random. But what about intermediate values of $p$? Does the distinguishing problem become significantly more difficult even if $p\ll 1$?
Usually what you call "information theoretic hardness" is denoted as statistical indistinguishability. And it is pretty much black and white only: Two distributions are distinguishable or not.

When you ask "how much harder", you already drift into the area of computational indistinguishability. There are plenty of ressources for that keyword, including most books about introduction into cryptography.

So the actual answer to your question would be "If the distribution of p is distinguishable (which is the case for any $p\neq1/2$), and the distribution of the PRNG is distinguishable, then your construction is distinguishable (from a truly random distribution)"