Does everyone make big mistakes? It is sometimes said that we all make big mistakes.  Is this true?
As a starting point, 'big mistake' could be defined as a mistake which we do unconsciously for months, and for which the implications endure for more than a few months.
What is the best approach to recover from 'big mistakes'?
I think the simple and obvious answer to this question is &quot;Yes&quot;.  That is, everyone at some point in their life is likely to make a 'big mistake'.
Regret is the likely emotion felt subsequent to making a 'big mistake' and is a well researched topic as per the references below.
There are countless situations in which an individual is likely to feel the emotion of regret, including: divorce, bankruptcy, loss of a close friend, self-inflicted injury, resigning from employment in a rage, being sentenced to jail etc. (The examples chosen here are likely to reflect instances where the big mistake endures for more than a few months.
Clinical psychology is the profession with specific training for helping individuals move on from their mistakes and overcoming a deep-set emotion of regret.
References

Connolly T, Zeelenberg M. Regret in Decision Making. Current Directions in Psychological Science. 2002;11(6):212-216. https://doi.org/10.1111/1467-8721.00203

Sweis BM, Thomas MJ, Redish AD (2018) Mice learn to avoid regret. PLoS Biol 16(6): e2005853. https://doi.org/10.1371/journal.pbio.2005853