Neural correlates of pleasantness and unpleasantness There are some basic cases of stimuli that are typically experienced either as pleasant or unpleasant, e.g. the major third as opposed to the tritone.

Assuming that there are different processes going on in my brain while listening to these two intervals, I'd like to know: What are the qualitative differences between these processes that would allow to understand that the first is experienced as pleasant and the other is experienced as unpleasant.

Just by thinking about it, there seem to be three possibilities:


The same regions/areals/neuron groups are active but in different characteristic modes, exhibiting different spatio-temporal patterns of neural activity.
Different regions are active in different modes.
Different regions are active but in somehow similar modes.


Assuming that the difference is mainly due to different activity modes (cases 1 and 2), I would like to know which characteristics might correlate with the pleasantness and unpleasantness of the expericence, e.g. some kind of "harmony".
Simply put, pleasant/unpleasant sensations are associated with the activation of certain brain regions:


  Many affective stimuli are hedonically complex mixtures containing
  both pleasant and unpleasant components. To investigate whether the
  brain represents the overall affective value of such complex stimuli,
  or the affective value of the different components simultaneously, we
  used functional magnetic resonance imaging to measure brain
  activations to a pleasant odor (jasmine), an unpleasant odor (indole),
  and a mixture of the two that was pleasant. In brain regions that
  represented the pleasantness of the odors such as the medial
  orbitofrontal cortex (as shown by activations that correlated with the
  pleasantness ratings), the mixture produced activations of similar
  magnitude to the pleasant jasmine, but very different from the
  unpleasant indole. These regions thus emphasize the pleasant aspects
  of the mixture. In contrast, in regions representing the
  unpleasantness of odors such as the dorsal anterior cingulate and
  midorbitofrontal cortex the mixture produced activations that were
  relatively further from the pleasant component jasmine and closer to
  the indole. (The Journal of Neuro Science)