How to take advantage of the withdrawal symptoms of antidopaminergics? So this may be a stupid question as I am not trained in neuroscience or psychology at all, but I had an idea about a somewhat counterintuitive approach to psychotropics and was wondering whether if it was at all scientifically sound and feasible.
To distill my theory, it's basically that in the same way prolonged cocaine abuse can make you chronically unhappy and apathetic, could we encourage some sort of controlled antipsychotic abuse to make you chronically happy and energized? My thinking is this:
Since the mechanism of antipsychotic drugs in an oversimplified sense is just to decrease dopamine, naturally when you withdraw your brain would respond by having an increase of dopamine. More specifically, since your brain overreacts to the antipsychotics it starts dramatically over sensitizing your brain to dopamine. So it seems to me that the reverse effect of the withdrawal is way more powerful than the direct &quot;purpose&quot; of the drug (this is in a sense how I understand the condition of tardive dyskinesia).
My thought is that this approach is particularly advantageous for the long-term use of physiatric drugs since in the long term the use of physiatric drugs has very little effect (and can sometimes even entrench mental illness further). Because of the fact that when dependence is developed the brain's structure and functioning in response to the ongoing presence of psychiatric medication is changing, it seems that developing drugs whose intended effects come from withdrawal would help resolve issues surrounding tolerance (as protracted withdrawal can sometimes last for years after the last dose of a drug was taken).
Is it viable to use a drug originally meant to suppress dopamine transmission to induce tolerance and thus increase dopaminergic effects to treat another disease where more dopamine is needed? For instance, can we use the anti-dopaminergic compound haloperidol to induce tolerance to address lower concentrations of dopamine transporters in people with ADHD, as opposed to using amphetamines?
Short answer
Taking dopamine antagonists leads to serious side effects, and stopping taking them leads to other, equally nasty side effects. None of them include happiness or feeling energized.
Background
So basically, based on our discussion in the comments, I think you are after the following:

Is it viable to use a drug originally meant to suppress dopamine
transmission to induce tolerance and thus increase dopaminergic
effects to enhance dopaminergic transmission to enhance mood and happiness after stopping the drug to reap the benefits of long-term 'withdrawal' symptoms?

First off, drugs targeting the dopaminergic (DA) system are associated with serious negative side effects. To step into the class where you are after, the classical anti-psychotics that inhibit DA signaling are associated with the following side effects (taken from the page on haloperidol from WebMD):

dizziness

lightheadedness

drowsiness

difficulty urinating

sleep disturbances

headache

anxiety

in rare cases sometimes permanent tardive dyskinesia, a nasty side effect marked by stiff, jerky movements of the face and body, muscle twitches, eye blinking, tongue thrusting, uncontrollable shaking, or arm waving.

rarely neuroleptic malignant syndrome occurs including: fever, muscle stiffness or muscle pain or muscle weakness, tiredness, confusion, sweating, fast/irregular heartbeat, dark urine, and kidney problems.

And the list goes on, and on, and on (see also Drugs.com)

Long term-use may lead to drug-induced Parkinsonism, which is actually the second most common cause of Pakinsonism in older people, after Parkinson's syndrome (Thanvi &amp; Treadwell, 2009.


Now fast forward to your withdrawal state that should make you happy, as dopamine transmission may indeed be exacerbated. The tolerance to haloperidol comes, at least in part, because D2 transmission is enhanced in the striatum in the brain (Ginovart et al., 2009)0. This leads to the dreaded tardive dyskinesia.
Abrupt stopping haloperidol intake after chronic use results in side-effects on their own in psychotic patients (apart from re-inducing psychotic states), namely (Bronson, 1993):

nausea and vomiting
sweating
as well as a relapse into psychosis characterized by anxiety, depression and internal chaos. Interestingly, the authors conclude that the so-called relapse into psychosis may actually be caused by withdrawal instead of the underlying disease state .

In all, happiness doesn't seem part of the deal of acute withdrawal from a well-investigated dopamine antagonist, unfortunately. Taking them is a pain, and stopping them abruptly is also not a pleasant thing to do either. When you slowly decrease dosage the withdrawal side effects will be less severe.
References
- Bronson, Life Sci (1993); 52(16): PL129-33
- Ginovart et al., Neuropsychopharmacology (2009); 34: 62–671
- Thanvi &amp; Treadwell, BMJ (2009); 85(1004): 322