Is it safe to store a wheel/tire set in my garage loft area?
I'm no expert, but I suspect that there won't be any harm in storing them there. I assume, they are just your seasonal tires? Someone had to be up there to install the shelving, which would have been more weight concentrated in a smaller area (a foot). So the distributed weight of the tires should have no effect. In my In-laws garage, they store all sorts of stuff up there, bins and boxes full of clothes and other things.