How do I hook up sink to offset drain
What you want to do is run the p-trap parallel to the back wall within the space between the wall and the back of the drawer.

If there is adequate space, start with a wye directly onto the pipe as it comes out of the wall with a line cleanout glued into the end of the wye (if there isn't enough space, use a 45 elbow). Use a fitting 45 or regular 45 elbow (again, depending on the available space) into the side outlet of the wye, then a short piece of pipe and the p-trap. Now you can go vertical along the back wall, then use two 90 elbows to offset to the sink's tail piece.