Any experience with Metwood joist reinforcers?
Follow the link provided by @Jack (How to cut hole larger than 1/3 of joist?), but note that the only entity that matters is your AHJ. 

Bring them the engineering specs from Metwood (https://www.metwood.com/wp-content/uploads/2019/01/CCRR-0279.pdf) and see if the answer is yes/no/need-more-information.