Radon remediation in a part-time home
Edited; I have only read testing reports and wired abatement pumps. I modified my answer based on the feedback. As I have said in other posts granite especially pink or rose can be a significant source of radon.
I would not run the system while you are away, I probably would open the house lower level windows or vents when you arrive. You may even want to set up a automated system that you can remotely turn on the abatement system the day prior to your arrival.  Exterior vents at the lowest level with make up air for a while would purge the home of this gas and purging and having the system running prior to arrival might work fine but test to verify if the numbers are low this can save $$$!