Centos 6.2 mysql configuration file help
The first thing you should configure is the innoDB buffer pool size. According to this blog entry by Percona, the ideal buffer pool size is 10% larger than your total data size.

Other settings to add: InnoDB log file size, query cache size. 

innodb_buffer_pool_size=12G

query_cache_size=500M

innodb_log_file_size=64M