I'm trying to enable SQL Filestream on Windows Server 2012 and SQL Server 2016 64 bit, Management Studio 2017
Root Cause?

During October we installed SQL Server 2016 on the server – but the desktop icons were still set to SQL Server 2017. When I used the 2016 Configuration Manager, it seemed to work.

Multiple versions installed on TEST Server:



Configuration manager on TEST Server with Configuration Manager 2017:



SQL Server Version on TEST Server:



Using SQL Server 2016 Configuration Manager:



So basically we were running the wrong version of configuration manager. Also we did a server restart. When I had previously tried to configure it on both 2016, 2017 configuration manager, it didn't work.