LOAD DATA (400k rows) INFILE takes about 7 minutes, cannot kill the "logging slow query" process?
The query under process ID 180233 looks like it is in distress.
Here is the query itself
SELECT COUNT(DISTINCT A.`campaignid`)  INTO _c
FROM `ox_campaigns` A 
INNER JOIN `selfserving_users` B ON B.`user_id` = A.`uid`
INNER JOIN `v3_cam_date` C ON C.`campaignid` = A.`campaignid`
WHERE A.`revenue_type` = 5 AND A.`deleted` = 0
AND A.`expire` = DATE_ADD(CURRENT_DATE, INTERVAL 1 DAY) 
AND A.`isExpired` = 0
AND IF( NAME_CONST('_permitid',3) = -1, 1=1,
IF( NAME_CONST('_permitid',3) = 0, A.`uid` IN
(SELECT C.`user_id` FROM `selfserving_users` C
WHERE C.`groupid` =  NAME_CONST('_groupid',12) ) ,
A.`uid` =  NAME_CONST('userid',388)));

The scary part about the query is the self-reference
You have selfserving_users acting in a self serving manner against itself.
Sometimes, the MySQL Query Optimizer will play a bait-and-switch, smoke-and-mirrors games with data, especially with a self reference, in order to formulate the best EXPLAIN plan possible. While mysql is very capable of completing sub-SELECTs, it can be still be expensive.
However, this is just a symptom that manifested because of Process ID 97. What is really the issue here?
LOAD DATA INFILE against an InnoDB table could make mysqld a little punch drunk. I don't believe (or at least I don't exercise full confidence) you can encapsulate it as a normal transaction although this was addressed back in MySQL 5.0.
Just picture it:

You are hammering the InnoDB Buffer
Some memory swapping may be going on
Possible full table locking issues that are affecting data pages outside the v3_zone_date table (such was with the selfserving_users table)

There may be a way to throttle the LOAD DATA INFILE process on an InnoDB table. I cannot give you a solid answer on this one, but try this link from Baron Schwartz.
UPDATE 2012-02-22 12:00 EST
There is open bug report in MySQL 5.5.7 called Deadlock when DDL under LOCK TABLES WRITE, READ + PREPARE. At the bottom of the report, a person complained about a block problem cause by the explicit LOCK TABLES.
Launching a COMMIT on locked rows in a table would hang because of trying to unraveling MVCC data assocaited with the locked rows. Based on the InnoDB Status you have shown, there would exist 6933 row locks on the table you are importing. I know that in Oracle, when introducing new rows to a table, MVCC is still generated because the previous version of the newly inserted row is a nonexistent row. The same must be occurring for InnoDB.
UPDATE 2012-02-22 12:42 EDT
In your question you stated the following about your .NET process

LOCK TABLES;
SET autocommit=0;
SET unique_checks=0;
SET foreign_key_checks=0;
LOAD DATA;
COMMIT;
UNLOCK TABLES;
SET autocommit=1;
SET unique_checks=1;

All of these events are running within the same DB Session. This is also happening within one DB Connection. Thus, this is not a deadlock in the traditional sense. It is just a case of blocking your COMMIT within a given DB Connection/Session because the tables were locked within the same DB Connection/Session.
UPDATE 2012-02-23 19:00 EDT
I would change the sequence to be this:

SET autocommit=0;
SET unique_checks=0;
SET foreign_key_checks=0;
LOCK TABLES;
LOAD DATA;
UNLOCK TABLES;
COMMIT;
SET autocommit=1;
SET unique_checks=1;
SET foreign_key_checks=1;

Please remember, a COMMIT cannot proceed if you have the tables locked in serial fashion. Therefore, UNLOCK TABLES must precede COMMIT.