How to reload a linked server?
I believe something is missing in the configuration done for DB2 Link.

the connection string should looks like this First.

Provider=DB2OLEDB; User ID=db2user; Password=mypassword; Initial Catalog=mydatabase;
Network Transport Library=TCP; Host CCSID=37;PC Code Page=1208;
Network Address=111.111.111.333; Network Port=446; Package Collection=MSDB2COL; 
Process Binary as Character=False; Connect Timeout=15; Units of Work=RUW;
DBMS Platform=DB2/AS400;Defer Prepare=False;Rowset Cache Size=0; Max Pool Size=100;
Persist Security Info=True;Connection Pooling=True;Derive Parameters=False;


Please add missing parameters, so system will not set Automatic/rando parameters, that should solve the issue.