Using AWS DynamoDB Geospatial index with Python
The "geospatial feature" of dynamodb isn't really anything else then calculating a geohash from the coordinates, storing the hash in the same row, create an index on the hash, and when querying based on a location, calculate the hash of that location and compare to the indexed hashes in the table. The algorithm of geohash is really simple and with a reasonable knowledge it could be coded in a couple of hours in any language. You could even create a lambda function (since October 2015 even in Python!) that is attached to a dynamodb stream and stores the geohash automagically. 

But probably it is a much better idea to check out dynamodb streams + lambda + cloudsearch integration that has native support for geospatial queries and boto also has a cloudsearch interface.