Database Backup from 2008 R2, Restore on 2012 Failover Cluster Instance
Does this failover cluster impose any restrictions on this backup restore or will it be a normal backup restore operation.


It will be a normal backup and restore operation (provided there are no other issues with the actual backup and/or restore).

The fact that you are going from a standalone instance to a failover cluster instance will not negatively affect an otherwise normal backup and restore.

The same rules will apply here, of course, as well as any other backup/restore operation regardless of standalone or FCI.