import data from csv to mysql - good database structure
You will want to have two database tables for this.

One table with id int/bigint autoincremenmt, site, time and prod.
id is the primaty key.

And one table with id (same as in previous table but no autoincrement, it refers to the id in the first table)  the number of the EST, and EST . The primary key of this table would span two columns, id and number of the EST (this may require some fiddling with the database table creation tool you are using).

As for date columns, no mysql doesn't understand that format, it has its own date and datetime formats for columns. At our place here we are using unix timestamps and store these in the database as integers or bigints.