Single Publication With Multiple Subscribers
Make sure distribution database is set up correctly with data and log file sizes based on the volume of data you are planning to replicate. I am not sure which version of SQL you are using, but i had issues when i was replicating from 1 publisher to 2 subscribers in SQL 2008 during re initialization. My issue was related to virtual memory being maxed out at one subscriber. It may not be applicable in your case.