SQL Server 2008, switching to simple recovery mode
What exactly do you mean by "remove the transaction log entirely"? I only ask because if you mean that literally the only possible answer is "You can't do that and have a working database".

This is a good article to explain the implications of changes to recovery mode and what it does for you.

Can't remember if all the steps are needed, but what I did last time was change recover mode to simple, carry out a backup then carry out a file shrink operation on the database (Right click on the database in the management centre and choose the option to shrink files that's in there somewhere)