Unable to install 64-bit Oracle 10g Release 2 ODAC 10.2.0.3 for Windows x64 on 64 bit Windows Server 2008 R2
I think That version of ODAC is not certified on Windows 2008 R2. Please use the regular Oracle DB Client that supports Windows 2008 R2. If you need to use ODP.NET 10.2, then go here:
http://www.oracle.com/technetwork/database/10204-winx64-vista-win2k8-082253.html

It can be very helpful to You.