Restore a clustered SQL database from a specific time
There isn't a difference between a restore on a standalone instance and one on a Failover Cluster Instance. There IS a difference if it is in an Availability Group.

Yes you can restore the FULL from Monday and the LOG from 9pm. 

Whether or not you have to restore the system databases is dependent upon what you are needing to recover. If it's just data in the user database, then simply restoring the user database is sufficient.