Can I Configure Enterprise Manager Cloud Control on Standard Edition
Is it possible to configure enterprise manager cloud control on Oracle 12c Standard edition?


Infrastructure Repository Databases


  The infrastructure repositories for RMAN, Oracle Enterprise Manager
  Cloud Control, AWR Warehouse, and Global Data Services Catalog can be
  shared in one database, or deployed in separate databases. Enterprise
  Edition must be used for the infrastructure repository database(s).



Will it administer multiple databases (Non-CDB)?


Yes, that is the point of a central monitoring environment.


What about administering databases on different servers?


Yes, same as above.