Is it possible to recover from a LOST_EVENTS incident from an RDS read replica?
In this specific case (a failed grant statement) stopping the slave, skipping the event, and restarting the slave is likely a safe operation... you just have to do it the RDS way.

mysql&gt; CALL mysql.rds_skip_repl_error;


This is one of several stored procedures installed on every RDS instance that partially make up for the lack of SUPER privilege.

http://docs.aws.amazon.com/AmazonRDS/latest/UserGuide/Appendix.MySQL.CommonDBATasks.html