Error 0x80131904 failed to load assembly id 65536 / HRESULT: 0x8013150A for microsoft.sqlserver.integrationservices.server
Have you tried this: 

USE &lt;DATABASE&gt;;
EXEC sp_configure 'clr enabled' ,1
GO

RECONFIGURE
GO
EXEC sp_configure 'clr enabled'   -- make sure it took
GO


First Enable Trustworthy database property

ALTER DATABASE [DatabaseName] SET TRUSTWORTHY ON;
GO


And change the database owner to ‘sa’

USE [DatabaseName]
GO

EXEC sp_changedbowner 'sa'
GO