Recommended innodb_file_per_table value for AWS MySQL RDS database
Complex answer

All tables are "small"?  Use =0.
All tables are "large"?  Use =1.
A mixture?  You could do some one way, some the other.  Such as using file_per_table=1 for tables over 10MB.

Simple answer

OK, that is more complexity than you would like.  In that case, let's go with the "short answer":  Use whatever AWS has it set to.  It won't matter much.

In particular, none of the metrics you quoted raise any alarms saying that you must go one way or the other.