Can I remove #sql_ .MYD files?
By all means, remove them. Those are just temporary tables mysqld had written to disk.

In all likelihood, mysqld probably crashed when those temp tables were made.

Look at the timestamps:


Max is 2012-10-09
Min is 2012-08-21


The sum of these files are over 1G. They are just taking up room.

I know they are temp tables because


MySQL uses MyISAM as the Storage Engine for Temp Tables
Temp Tables have no .frm, which prohibit DB sessions from accessing them directly in SQL


You can remove the corresponding .MYI files as well. Those are the index file components of teach temporary MyISAM tables. They are never populated because temp tables are never indexed.