How to get the most out of MySQL on a QuadCore machine with 16 GB of RAM?
Since you are running MySQL 5.5, you may want to consider configuring InnoDB to access multiple cores

Here are the settings you should be using

innodb_thread_concurrency sets the upper bound on number of concurrent threads that InnoDB can hold open. Best round number to set for this is (2 X Number of CPUs) + Number of Disks. UPDATE : As I learned firsthand from the Percona NYC Conference, you should set this to 0 in order to alert InnoDB Storage Engine to find the best number of threads for the environment it is running in.

innodb_concurrency_tickets sets the number of threads that can bypass concurrency checking with impunity. After that limit is reached, thread concurrency checking becomes the norm again.

innodb_commit_concurrency sets the number of concurrent transactions that can be committed. Since the default is 0, not setting this allows any number of transactions to commit simultaneously.

innodb_thread_sleep_delay sets the number of milliseconds an InnoDB thread can be dormant before reentering the InnoDB queue. Default is 10000 (10 sec).

innodb_read_io_threads and innodb_write_io_threads (both since MySQL 5.1.38) allocate the specified number of threads for reads and writes. Default is 4 and maximum is 64.

innodb_replication_delay imposes thread delay on a slave is innodb_thread_concurrency is reached.

Here are my past posts on MySQL 5.5 and activating multiple cores for InnoDB


Jun 01, 2012 : I&#39;ve got 16GB of ram, how should I configure MySQL Server?
May 07, 2012 : MySQL Server Performance
Apr 26, 2012 : Is the CPU performance relevant for a database server?
Mar 16, 2012 : Using multiple cores for single MySQL queries on Debian
Oct 07, 2011 : Should I use a storage engine other than MyISAM to optimise these tables or should I get better disks?
Sep 20, 2011 : Multi cores and MySQL Performance
Sep 12, 2011 : Possible to make MySQL use more than one core?