Von Neumann architectures and quantum computing
What do you mean by von Neumann architecture? 

I'll use the Wikipedia definition, and say that it's a computer which keeps its program and its data in the same random-access memory. This works well as a theoretical model of a quantum computer, but there are severe drawbacks to implementing such a device. In particular, for a quantum computer, the data has to be quantum. If the data and program are stored in the same memory device, this would imply that the program has to be quantum, as well. So the computer would then have to be able to implement a superposition of instructions in its instruction set. This is orders of magnitude more difficult experimentally than just having the memory in superposition.

In fact, even indirect memory retrieval, including RAM, pointers, and so forth, appears to be quite difficult to implement experimentally. 

This has resulted in the default model of a quantum computer being the uniform quantum circuit model, which is both easier to imagine implementing experimentally and tractable to deal with theoretically from a TCS perspective. The circuit model is able to simulate the von Neumann architecture with only a polynomial slowdown, so quantum complexity classes are not changed by this change of model.