What kind of game (in Scratch) would require use of a list?
A variant on the usual random drill and practice test would be to pre-populate with the questions and answers, then remove question and answer from each as they get answered correctly, allowing players to get more practice on the questions they get wrong. Here's an example for times tables.

You could try something for an adventure game, building up an inventory of items collected in a list. Another possibility would be an adaptive 20 questions style game, adding additional questions into a database (of sorts) as the player gets to the end of a branch of the tree.