What randomness really is
The short answer is that no one knows what real randomness is, or if such a thing exists. If you want to quantify or measure the randomness of a discrete object, you would typically turn to Kolmogorov complexity. Before Kolmogorov complexity, we had no way of quantifying randomness of say a sequence of numbers without considering the process that spawned it.

Here's an intuitive example that was really bugging people back in the day. Consider a sequence of coin tosses. The outcome of one toss is either heads ($H$) or tails ($T$). Say we do two experiments, where we toss a coin 10 times. The first experiment $E_1$ gives us $H,H,H,H,H,H,H,H,H,H$. The second experiment $E_2$ gives us $T,T,H,T,H,T,T,H,T,H$. After seeing the outcome, you might be tempted to claim there was something wrong with the coin in $E_1$, or at least for some weird reason what you got is not random. But if you assume both $H$ and $T$ are as probable (the coin is fair), the probability of obtaining either $E_1$ or $E_2$ is equal to $(1/2)^{10}$. In fact, obtaining any specific sequence is as probable as any! Still, $E_2$ feels random, and $E_1$ does not.

In general, since Kolmogorov complexity is not computable, one can't compute how random say a sequence of numbers is, no matter what kind of claimed "totally random" process spawned it.