Proving that if $\mathrm{NTime}(n^{100}) \subseteq \mathrm{DTime}(n^{1000})$ then $\mathrm{P}=\mathrm{NP}$
Here is the solution using padding. Suppose $L \in \mathrm{NTime}(n^{1000})$. Define a new language $L' = \{x0^{|x|^{10}-|x|} : x \in L\}$. Each $x \in L$ corresponds to some $y \in L'$ of length $|y| = |x| + (|x|^{10}-|x|) = |x|^{10}$. Therefore we can decide whether $y \in L'$ in non-deterministic time $|x|^{1000} = |y|^{100}$, i.e. $L' \in \mathrm{NTime}(n^{100}) \subseteq \mathrm{DTime}(n^{1000})$. In order to decide whether $x \in L$, form $y = x0^{x^{10}-|x|}$ and run the $|y|^{1000} = |x|^{10000}$-time deterministic algorithm for $L'$. We conclude that $L \in \mathrm{DTime}(n^{10000})$.