No number is equal to Zero, is this statement true or false?
It is false if and only if there is a number that is equal to zero.

"There is a number that is equal to zero" is true if and only if zero is a number. Without any context (there might e.g. be some very strange definitions given earlier in the exercise), we cannot say whether zero is considered a number in this case. If there is no other context given in the exercise, it should be clear that zero is a number.

For example, the domain of discourse might be only positive integers*, when zero is not a number, but then it would be very weird to use the word "zero" in the sentence in the first place.

*The set of natural numbers has two contradicting definitions, $\mathbb{N}=\{0,1,2,\dots\}$ (non-negative integers) and $\mathbb{N}=\{1,2,\dots\}$ (positive integers). This might be the source of confusion in your case.