Is it safe to use PBEWithMD5AndDES?
Yes, it can be decrypted easily because it will use DES (CBC) mode of operation. DES only has an effective key size of 56 bits. So the key and the can be brute forced regardless of the (PBKDF1) key derivation.

MD5, while considered broken by itself, is less of an issue when it is used within PBKDF1 - as long as the password contains enough entropy of course.

If possible you should upgrade to Password Based Encryption (PBE) using PBKDF2 and AES. Beware that PBE usually uses CBC mode encryption, so it is not suitable for transport protocols.