In RSA, why is it important to choose e so that it is coprime to φ(n)?
It doesn't become vulnerable; instead, it becomes impossible to decrypt uniquely.

Let us take the example you give: $N=65$ and $e=3$.

Then, if we encrypt the plaintext $2$, we get $2^3 \bmod 65 = 8$.

However, if we encrypt the plaintext $57$, we get $57^3 \bmod 65 = 8$

Hence, if we get the ciphertext $8$, we have no way of determining whether that corresponds to the plaintext $2$ or $57$ (or $32$, for that matter); all three plaintexts would convert into that one ciphertext value.

Making sure $e$ and $\phi(N)$ are relatively prime ensures this doesn't happen.

BTW: when you generate an RSA key, common practice nowadays is to select $e$ first, and then when you select the primes $p$, $q$, you make sure that $p-1, q-1$ are relatively prime to $e$; this is equivalent to making sure that $e$ and $\phi(N)$ are relatively prime.