What canon do you follow to modify the Buddha's views as knowledge advances?
It would depend on the information, but when in doubt, I go back to the basics of the Four Noble Truths, and the Buddha's last words of "Be a light unto yourself." and would see where the new information fit in with those. Without an idea of how a Teaching might be disproved, it is difficult to speculate. 

If ultimately, it was somehow proven, and I feel this is unlikely, the Teaching is incorrect, then another path would need to be considered.