Difference between two drivetrains with the same gear ratio?
The gear ratio is exactly the same, the only possible difference is in the efficiency of the power transmission. Big/Big is generally more efficient, so it should be better for both, unless there is some reason that greater power losses in the transmission chain help "spinners". 

So they will potentially feel different if you can notice the difference 
( pretty small ) in the efficiency of the drive train. I don't see how that translates to masher vs spinner though. 

http://www.ihpva.org/HParchive/PDF/hp50-2000.pdf