Best way to patch road bike tubes
When I make a repair, I also do the following extra steps, to make sure that the patch holds. I have never had a patch come off/leak when using this technique.


Use a little bit of sandpaper to remove any ridges on the area to be patched, such as a manufacturing join.
Clean the area to be patched, this makes the glue/solution adhere better to the tube. Especially so if you have sanded the area. I would usually use methalyated spirits and a lint free cloth of some sort.
Once the patch is applied, apply some chalk dust to the area, this makes sure that the solution/glue does not bond to anything else.