I want to replace 52/36 chainrings with 50/34 chainrings on a Praxis Works
Looking at the road Praxis chainrings page, 52/36 through 48/32 ring sets are all offered in 110mm BCD. All the roads cranks seem to have an evenly spaced 5 bolt pattern.

Without knowing exactly what crank you have I can't say for sure, but it seems likely you can fit smaller rings.