Convert road bike mechanical disc brakes to hydraulic
It is possible using special convertors that have a hydraulic fluid reservoir that is controled by the cable from your brifters. Giant makes such an upgrade kit https://www.giant-bicycles.com/gb/conduct-hydraulic-disc-brake-upgrade-kit There are also brakes that have hydraylic fluid only in the caliper itself such as TRP HY/RD.
Otherwise, the same limitations I discussed at https://bicycles.stackexchange.com/a/72522/21133 apply. Shimano only.makes brifters from 10 speed above and those different cable pull ratio for shifting.