Transition between hybrid bike and endurance road bike
You probably just have to get used to the geometry of the endurance road bike (since most hybrids are closer to MTB hardtail geometry), which can be helped with bike fit, so the drop bar and saddle are positioned in a way where you can use all the hand positions of the bike (hoods, drops, middle of the bar, sides, etc.) efficiently and comfortably for the type of riding you're doing. 

Also, you should be more aware of road hazards, since most endurance road bikes have weaker wheels than a hybrid, to save weight - bunny hopping can be useful for this. 

Also, if you're using clipless pedals (or clipped pedals) on the road bike and not on the hybrid, make sure to practice clipping in and out before you hit the road (unless you like your face hitting the ground...)