Can we use Shimano XTR 2x11 speed shifter with Shimano 2x11 Dura-Ace RD and FD?
Shimano 11 speed MTB and road derailleurs and shifters are not compatible. The cable pull per shift and derailleur actuation ratios are different. See this Art's Cyclery page](https://www.artscyclery.com/science-behind-the-magic/science-behind-the-magic-drivetrain-compatibility/).

The MTB groups use a longer cable pull to be more reliable in dirty conditions.

While rear derailleur cable pull/actuation ratios are well documented, front ones are not, but I have to assume 11 speed MTB and road groups use different pulls and are not compatible.

MTB double cranks typically have a 10 tooth difference between rings whereas roads cranks have a 16 tooth difference. Cages on MTB front derailleurs are therefore smaller and will not work with road cranks.