How do mining pools distribute work effectively?
Traditionally, pools gave miners work units covering the entire nonce range 0-4,294,967,295. When the miner finishes work, he requests a new work unit with a different extraNonce (or payout address). Different miners also get work units with different details.

To reduce load, pools are now moving on to a setting where the miner can himself change details of the generation transaction and compute the Merkle root, so he can do as much work as he pleases without needing new assignment from the pool.