Bitcoin rig setup, connecting a Butterfly Labs unit using USB
I don't think it will make a difference.  If you are using the Anker 10-port "power bar" style USB hub (that's what it sounds like you have, based on your description of it + the fact that this hub is very commonly used with USB bitcoin miners), that is a pretty robust hub.  One of my mining rigs (which doubles as my media center) has 8 block erupters + USB fan + an external USB hard drive on it, and all devices function without any difficulty.