Chromosome 2 alternate explanation - apes gaining a set of chromosomes?
I guess part of the question is...what exactly are you bring up Chromosome 2 as evidence of, exactly?  It's evidence of that chromosomal rearrangements are possible, but that isn't terribly helpful to you, so I'm not sure why you are bringing it up.

I think the fusion is a rebuttal to a claim that the disparate # of chromosome is a problem for the claims of common ancestry between humans and other apes, but if they don't mention it, I'm not sure why you would need to use that particular fact.

Have you consulted talkorigin's 29 evidences of macroevolution?  Lots of good stuff there.

http://www.talkorigins.org/faqs/comdesc/