Can the Na+/K+ pump backwards to generate ATP?
All enzymes can theoretically catalyze the reverse reaction.

Researchers have driven the Na+/K+ ATPase to synthesize ATP with artificial ion concentrations:


  We have studied the apparent affinity for K at its intracellular discharge sites by measuring the rate of ATP synthesis as a function of the internal K concentration in resealed red blood cell ghosts, where the Na-K pump is driven in reverse by the downhill efflux of K and influx of Na…