What does "radiographic progression" mean in cancer?
"Radiographic" refers to imaging modalities like x-rays, CT scans, MRI, etc.

"Progression" in medical terms is referring to progression of disease, where progression means advancing to the next stage, getting worse, etc.

Radiographic progression in the context of cancer would mean that based on X-rays, CT, MRI, etc, the cancer has gotten worse in some way. The exact meaning of progression has to be defined on some rating scale and will differ from study to study. Radiographic progression is not the only way to measure disease progression, other measures can also be used like symptoms experienced.