Where’s the flaw in my proposed TB Treatment?
High oxygen concentration can be deleterious; it can induce oxidative
damage.
The systemic blood circulation would supply oxygen to the
"oxygen-deprived" lung.
Moreover, Mycobacteria can survive in anaerobic conditions.


And what if both lungs are infected? There are many flaws in the proposed therapy.

Adding this point from one of the comments below:

There are several cases of extrapulmonary tuberculosis and in these cases treating just the lung would not make sense.