Exclusive microtubule minus-end labeling
γ-Tubulin is specifically localized to the minus end of microtubules. GFP labeled γ-Tubulin can be used to label the minus ends in-vivo and without the requirement of staining. Fan et al have developed a phage display antibody specific to α-Tubulin that can be used to visualize minus ends. See the figure below.

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The image is an electron-micrograph but it is certainly possible to do a fluorescent microscopy after IHC staining.