Analysis of dynamic connectome data?
C. Elegans is the only species with a fully characterized connectome and I don't believe there's been much electrophysiological work done on them. The GEVIs are still being optimized and have their own share of issues particularly with signal resolution - distinguishing between subthreshold changes in membrane potential vs action potential. See the embedded paper. If anything, it will be awhile before the response properties of the neurons in C. elegans are characterized. However, I'm sure you could try modeling smaller circuits where the connectivity and neural properties of the neurons are known.