How do I reverse my insert within a plasmid?
Design your 5' primer upstream of ProDpro. with a Spe1 cut site added to the end (plus a few extra random bases to allow for better cutting). Add an Xba1 cut site to the end of the 3' primer, again with a few extra random bases on the end to allow for better cutting. 

Amplify the insert, PCR cleanup, digest, cleanup again, and you should be able to easily clone into the Xba1/Spe1 digested vector that has been gel purified.