Help in understanding the IQ raw file format used by SDRs/GnuRadio
As @Marcus_Müller points out, dropping samples will corrupt whatever digital symbol or analog waveform you were operating on at that instant.

You'll also introduce discontinuities in the time domain, which means you'll get broadband noise in the frequency domain at that time.

Probably the worst effect is, that if you drop a half sample, you end up swapping I &amp; Q and the spectrum gets inverted.  Mathematically, if:

$$ x(t) e^{j\omega t} = I(t) + jQ(t) $$

then

$$ Q(t) + jI(t) = x(t)e^{-j\omega t +j\frac{\pi}{2}}$$

So you get spectral inversion about DC.  If your signal of interest was not centered and symmetric about DC, then your downstream DSP will yield junk.