How to convert time-domain signal to complex envelope?
These are the main ideas:


Consider a receiver that picks up a signal $r(t)$. This signal has bandwidth $W$ and is centered on carrier frequency $f_c$.
Using the Hilbert transform, eliminate the negative frequencies of $r(t)$. The resulting signal, $r_+(t)$, is called an analytic signal.
Now, downconvert the analytic signal using a complex exponential, so that the spectrum is centered around 0. This signal, called $\tilde r(t)$, is the complex envelope of $r(t)$. Its spectrum goes from $-W/2$ to $W/2$, and its bandwidth is $B=W/2$.
The complex envelope is almost always complex, but if the spectrum of $r(t)$ is symmetrical around $f_c$, the CE is real. Examples of this are AM DSB and BPSK.


In the transmitter you would do the opposite:


Start with a complex envelope $\tilde s(t)$ that represents the information you want to transmit. Its spectrum should go from $-W/2$ to $W/2$. An example would be a QAM signal with complex symbols.
Upconvert the CE to frequency $f_c$, multiplying by a complex exponential. The result is an analytic signal with only positive frequencies. The signal will be centered around $f_c$ and cover the frequency range from $f_c-W/2$ to $f_c+W/2$.
Take the real part of the analytic signal to convert it to a real signal that can be physically generated and transmitted.


All of these steps can be accomplished in Matlab. Be sure to read the documentation for the hilbert command. I can't comment on the corresponding Simulink blocks, since I don't use them.

Also note that it is very likely that you don't have to do all this. If you can perform all your simulations using the complex envelope, you'll save a lot of computing time. The reason is that the transmitted and received signals need to be sampled at least at a rate $2(f_c+W/2)$, whereas the complex envelope can be sampled at $W$ real samples per second -- a huge difference for large $f_c$.