Automatic detection of noise-only segments in audio
The way I read it, the algorithm works by figuring out where the signal part lives in the frequency domain by using the statistics of the noise part. This means you don't need a noise-only signal for each signal you want to process as long as the statistics of the noise are the same for each signal realization.
For example, if you had 1000 signal realizations that you want to perform this noise reduction on, you would use a noise-only signal to compute the statistics of the noise. Then using those statistics, the algorithm will figure out signal versus part by comparing to a threshold (average noise power or something I would guess).