Difference in information between IQ Sampling vs. Real Sampling at $2F_s$
The bandwidths might be the same.  I agree with Jason’s assessment.

Is there a difference?

Yes.  Let’s say we construct both signals such that their frequency domain’s are equivalent from $0-F_s$.  For the real signal the frequency domain would be limited to $X(F_s-f) = X^{*}(F_s+f)$.  For the complex signal it would be $X(f) = X(F_s+f)$.

Can the IQ signal be recreated from the real signal?

Yes.  Again, we assume the frequency domains are equal from $0-F_s$.  First, we filter the real signal to remove the frequency content from $F_s-2F_s$, which would result in an interpolated version of the IQ signal. Then we downsample by throwing away every other sample, yielding the IQ signal.  There are practical considerations, but that would be one way to go about it.