Overview Noise Reduction Techniques
The frequency domain conjugate multiplication (correlation) of the received signal with the reference signal followed by the power delay profile will provide you the overall signal to noise ratio. As explained in paper titled "SNR Estimation based on Sounding Reference Signal in LTE Uplink".

There are various noise reduction algorithm exist. Which will reduce the noise and will enhance the main expected signal component. There are adaptive filter which will converge to the expected value and depend on there performance, complexity is dependent. For example LMS, NLMS and RLS are the type of adaptive filters. Which will reduce the noise but the accuracy is directly proportional to the complexity. 

By filtering we can reduce the noise, but we cant remove it totally for example AWGN noise.