Waiting for one more reviewer due to being unresponsive - what to expect?
Closely related: What happens if a reviewer withdraws himself from peer review process?

If the reviewer is unresponsive, they effectively withdraw. Again the same basic options are available to the editor: they can find another reviewer, or they can make a decision based on the single review they've received. When you get the decision you'll be able to tell which option they took.

Does the fact that one of the reviewers who has already provided his/her reviews bears any significance in terms of revision, acceptance or rejection?

I suppose the fact the reviewer went unresponsive indicates that your manuscript is not so groundbreaking that people are actively excited to review your manuscript. But even drawing this conclusion is dangerous - the reviewer could simply have fallen ill, for example - so the brief answer is &quot;no&quot;. It's simply something too circumstantial to draw conclusions about.
On the bright side, having one review completed is progress, so you should expect to receive a decision in a shorter time than if you withdraw and submit the manuscript at another journal.