Are hand made posters acceptable in Academia?
You should present the best poster you can make

It is far easier to make a professionally looking, high quality poster using LaTeX or any other software than by hand-drawing it.

However, there are some really good artists out there who can manage to do a hand-drawn poster that looks better than a printed one could.

So don't use hand-drawing as a way to save time or money. A good hand-drawn poster is more work than any printed one.

If you are 100% certain that you can get your message across better with a hand-drawn poster, then go for it, otherwise use a printed one.