Do academicians routinely face discrimination in industry job searches?
I think of a PhD as "vocational education for researchers", not as the "highest level of education". So if a company is looking for a researcher then a PhD should be an advantage, but if a company is looking for a "spreadsheet jockey" as in your example then there is a mismatch between the education and the job and a company should take that into account.

On top of that there are large cultural differences between companies and universities. Such differences can lead to frictions, and if you can hire someone without such frictions then that will be an argument.