What to do when I’m not affiliated with an academic institution and submitting a manuscript?
Just list your affiliation as &quot;independent researcher&quot; and use a valid email address that you expect to maintain. You should be fine. Scholarship isn't for employed academics only. It is the quality of the work that matters most.
The only block I could see is if your research requires Ethics Board (such as IRB in the US) prior approval.
For the submission process any physical address will probably do if it is required. But for final versions to be published I would seek advice from the editor. Perhaps a post box would be preferred to a residence.