Applying to faculty jobs: how close to research area should I be?
You want a job? So apply. That’s all there is to it.
The academic job market is not some kind of neighborhood bonding event or support group where people try to be as nice as possible to each other and avoid hurting each other’s feelings. No one will be mad at you — in fact, the very notion that someone getting mad at you is a consideration you should take into account when deciding whether to apply for a job is, from my point of view as someone who in a typical year looks at anywhere between a couple of dozen and a couple of hundred job applications, completely absurd.
You might not get the job, but there’s nothing inappropriate about applying, unless there are formal requirements listed in the job application that you don’t satisfy.
Good luck with the job search!