Human-Computer Interaction PhD in Computer Science vs Information Systems: Does the department title matter?
If you are referring to high-tech industry job (vs academic jobs) I can only tell you that for me, if I'm looking for R&amp;D, design, development roles I would hire someone with a CS degree over IS degree without even looking into qualifications. It is unlikely I will look at you resume farther than the part that mentions your degree.  Unless of course I am unable to find people and am rather desperate. 

Think about it this way:  this is degree from Business/Economics department which translates into a non (engineering/technology) degree which is not what a job with CS requirement would be looking for. 

But again, it depends on kind of a job you are thinking about and can't claim  that this is the view of everyone although I can comfortably say it would cut your chances a good deal for the kind of jobs I mentioned above. 

Sorry if I sound harsh.