Grammatical mistakes and minor typos made during grant application
Typos are always detrimental. Especially in a short submission they will stand out and broadcast to the reviewer that you are not careful or did not take the submission seriously enough. This is true in other areas as well. I vividly remember as a kid watching a friend's dad flip through resumes of job applicants for his company. He would immediately throw away any that had typos, complaining &quot;how hard is it to make sure a 2-page resume is perfect?&quot;
Whether they are detrimental enough to fully sink your application depends on the reviewer and your application's strength otherwise.