Parenthesis in paper title?
There are many papers out there with parentheses in my title. In particular, there are at least three articles (from different publishers) starting with a parenthesis:


(Patho)physiological Significance of the Serum- and Glucocorticoid-Inducible Kinase Isoforms
(Patho)physiological implications of chronic dietary sodium restriction during pregnancy; a longitudinal prospective randomized study
(Patho)physiological implications of the novel epithelial Ca2+ channels TRPV5 and TRPV6


Thus, there is at least some publishers who do not object to this.

On the other hand, this probably does not hold for all publishers, and there very likely is at least one out there, who objects against parentheses in titles.

Unless there is a clear rule in the publisher’s guidelines, it will be impossible to predict its opinion on this matter. Thus, I would suggest to just use the parentheses and let the publisher or the copy editor, respectively, worry about this.