How is publishing in JoVE (a "video journal") perceived?
Based on our work with them, it seems to be a high quality publication. We published a JoVE article last year and several of the protocols we use in the lab are adapted from other JoVE articles. So it seems effective in its mission. The video format really works for certain protocols, and it may make it easier for people to reproduce your work (thereby getting you more citations).

That said, there is the price tag to consider, and the editorial process is extensive and time consuming (you write an article, then go through normal peer review, then work with them to turn it into a screenplay, then get everyone together with the videographer they provide, etc.). So I would say that if your method does not specifically benefit from the video format, there isn't an advantage over a conventional methods journal.

As far as how it's received, I haven't noticed any differences from any other small journal.