Why such a bizarre placement of 关于 in 请问关于解释《里》和《内》的区别?
请问解释关于《里》和《内》的区别 (would you please tell/answer me about explaining the difference between《里》and《内》)


This sentence is awkward because 请问 (would you please tell me) is a set phrase that should followed by a question instead of a demand/ request "解释关于" (explain about). 

The better phrasing would be:


请解释关于 《里》和《内》的区别 (Please explain about the difference between 《里》and《内》) 

关于(about) can be omitted 


or


请问《里》和《内》有什麼区别? (would you please tell/ answer me what is the difference between 《里》and《内》?)



  请问关于解释《里》和《内》的区别 (would you please tell/ answer me about explaining the difference between《里》and《内》)


Even worse! Not only 请问 is followed by a demand/ request '解释' instead of a question, the order of 关于 and 解释 is also wrong. It is not "关于解释" (about explain) but  "解释关于" (explain about)

"请问关于解释《里》和《内》的区别" is just a badly constructed sentence.