JetDrive 725 - SHould I use TRIM enabler?
I've had a 960GB JetDrive 720 since September 2014 and have been running Yosemite since release. I found that enabling trim on Yosemite caused instabilities, and the system would lock up very regularly. I was in regular contact with Transcend about this for a while. I like to think that the removal of trim from the JetDrive toolbox on Yosemite was down to my insistence, but we will never know for sure!

Turning of trim has solved all my problems. I did that in January 2015, and have not had any issues since. I work with a lot of virtual machines and this can be quite I/O intensive and I have seen no downsides of not enabling trim. I do boot into the recovery console about once a month to run Disk Utility to verify disk but I've not had any problems so this seems overcautious on my part. 

OS X 10.10.4 and later

Apple has included a command line tool that enables trim. If you're running 10.10.4 or later, be sure to save all open documents as the following commands will result in a system restart.


Launch Terminal
Type sudo trimforce enable. There will be some scary warnings about data loss, but this is standard CYA legalese. You will be prompted about whether you are sure twice.
This will reboot your system. After the reboot, TRIM is now enabled.