Delete all backups of specific file/folder with tmutil
I found this SU Q&amp;A titled: How can I delete Time Machine files using the commandline
 which demonstrates a method for deleting specific files from the CLI. This answer highlighted a method that sounds like what you want:


  My backup disk is full. I have a very large file (many gigabytes) that
  has been backed up for months. There is one physical copy of it, but
  many snapshots with hard links to that copy. To actually get rid of
  that file, I need to remove the hard link from every backup.


In that answer it was shown that one could use this method to delete a file:

$ cd /Volumes/WD\ 500G\ USB/Backups.backupdb/csm-laptop
$ ls -li */Macintosh\ HD/Users/csm/vm.img
...
2740350 -rw-r--r--@ 28 csm  staff  42949672960 Feb 17 16:12 2015-05-08-005636/Macintosh HD/Users/csm/vm.img
2740350 -rw-r--r--@ 28 csm  staff  42949672960 Feb 17 16:12 2015-05-08-015812/Macintosh HD/Users/csm/vm.img
2740350 -rw-r--r--@ 28 csm  staff  42949672960 Feb 17 16:12 2015-05-08-030036/Macintosh HD/Users/csm/vm.img
2740350 -rw-r--r--@ 28 csm  staff  42949672960 Feb 17 16:12 2015-05-08-041307/Macintosh HD/Users/csm/vm.img
2740350 -rw-r--r--@ 28 csm  staff  42949672960 Feb 17 16:12 Latest/Macintosh HD/Users/csm/vm.img


The method to delete the file uses a helper CLI tool included with Time Machine called bypass:

$ sudo bypass rm -f */Macintosh\ HD/Users/csm/vm.img


bypass's location

Since bypass is considered a helper script to Time Machine, it's location is not typically on your $PATH. Therefore you'll need to specify the full path to the executable. Additionally Apple has relocated it for different versions of macOS.


$ sudo /System/Library/Extensions/TMSafetyNet.kext/Contents/MacOS/bypass \
    rm -rfv /Volumes/[disk]/Backups.backupdb/[path]

  
  In 10.8 Mountain Lion, bypass moved into 'Helpers':

$ /System/Library/Extensions/TMSafetyNet.kext/Helpers/bypass

  
  In 10.10 Yosemite, bypass moved here:

$ /System/Library/Extensions/TMSafetyNet.kext/Contents/Helpers/bypass



References


How can I delete Time Machine files using the commandline