How can I temporarily disable hot corners when playing games (or other such full-screen apps) on Mavericks?
This is a quite old question, but I stumbled on it looking for the same thing (although on ML). The script looks interesting, but it's a bit far-fetched for me, I was looking for something simpler and preferably without add-ons.

This is what I found and works for me: in the hot corner's pref pane, hold Command, Option, Control and/or Shift after clicking a drop down list of a hot corner and you can add one or any combination of the modifier keys to a hot corner trigger. This way, they only work if and when you hold that(those) key(s) which you probably won't during a game, or any full screen app.

I'm pretty sure this works on all OS X versions.