Edirol UA-101 OSX Mojave Drivers
I have disabled SIP (System Integrity Protection) by entering the recovery mode (holding cmd+R on boot) and typing "csrutil disable; reboot" on a terminal.
Then I installed the latest driver available from the Roland website (the ones for Mac OS X 10.9) and after a reboot the UA-101 came back to life.
All of this was done on MacOS Mojave 10.14.2 on a MacBook Pro late 2016.
If you want more info head to http://osxdaily.com/2015/10/05/disable-rootless-system-integrity-protection-mac-os-x/