AppleScript for locking the screen in Catalina
You can use:

tell application "System Events" to keystroke "q" using {control down, command down}


You could also use the following instead:

tell application "System Events"
    set appName to (name of every application process whose frontmost is true and visible is true) as string
    click menu item "Lock Screen" of menu 1 of menu bar item "Apple" of menu bar 1 of application process appName
end tell


&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Hint: Mouse over and horizontal/vertical scroll to see full code. 

However, the first mentioned solution is more direct.