Why would an app constantly monitor /etc/passwd?
Adobe Desktop Service wasn’t looking at your /etc/passwd. Apple’s system library was.

Apple’s system library wanted to know your username so it can find your home directory. It then decided the best way to figure out your username was to look it up in /etc/passwd. Adobe Desktop Service just wanted to know the path to your home directory, and (correctly) used the CoreFoundation framework for that. That’s why the call appears under Adobe’s process.

Details

In your screenshot, the Caller entry says something like _fsi_get_user. This is the symbol of a private subroutine in one of macOS’s system libraries, libsystem_info.dylib, located in /usr/lib/system.

The public source code of the _fsi_get_user function reveals the following logic:

if (geteuid() == 0)
{
  // […]
}
else
{
  f = fopen(_PATH_PASSWD, "r");
  _fsi_get_validation(si, VALIDATION_PASSWD, _PATH_PASSWD, f, &amp;va, &amp;vb);
  fmt = 1;
}


Looking at the decompiled code in libsystem_info.dylib (for example, using Hopper Disassembler) confirms that _PATH_PASSWD is indeed the file name /etc/passwd. (The source code further down in file_module.c also explains why there’s a call to fstat immediately after the fopen: the implementation of _fsi_get_validation does that to figure out the last modification time of your /etc/passwd.)

In other words: Adobe wasn’t looking at your passwd file; Apple’s system library was.

Connecting the dots

There are many possible call stacks that may connect Adobe Desktop Service’s code to the _fsi_get_user function. A bit of static analysis suggests the most plausible candidate would be NSHomeDirectory, a utility class in Foundation.framework.

Looking at Adobe Desktop Service’s binary reveals that it indeed calls [NSHomeDirectory UTF8String]:

*100032ac4   call   imp___stubs__NSHomeDirectory
*100032ac9   mov    rsi, qword [0x10008a178]  ; "UTF8String"
*100032ad0   mov    rdi, rax
*100032ad3   call   qword [_objc_msgSend_100088350]


Apple’s implementation of NSHomeDirectory will then lead us to /etc/passwd fairly quickly. My educated guess on the most likely chain of function calls would be:

Adobe Desktop Service → [NSHomeDirectory UTF8String] (in Foundation.framework) → NSHomeDirectoryForUser → CFCopyHomeDirectoryURLForUser (in CoreFoundation.framework) → _CFCopyHomeDirURLForUser → getpwuid (in libsystem_info.dylib, re-exported via libSystem.B.dylib) → si_user_byuid (this is where Apple decides at runtime which source it’s going to use. For example, if your user ID is between 1 and 499, your /etc/passwd will be consulted instead of Directory Services.) → file_user_byuid → _fsi_get_user.

To be extra sure, I further analyzed the binary Adobe Desktop Service and as expected, it contains no single reference to /etc/passwd. (I haven’t checked whether or not Adobe Desktop Service does other shady things, though.)

The whole analysis would have been a little easier if you had actually clicked on one of the entries before you created the screenshot. Your app would then have shown the relevant stack trace in the bottom right corner (it’s the lines where it says Stack Trace). But hey, I had a lot of fun figuring it out, and I’ve learned a lot that way!

Verification

To confirm that my analysis is correct, you may want to click on one of the /etc/passwd entries in your Instruments app and find the terms NSHomeDirectory and file_user_byuid somewhere in the stack trace.