iPad Controls and Locks
Apple Configurator includes a feature that allows you to select an app to 'lock' a supervised device to. When supervising a device, you can Lock to App and the iPad will be unable to escape from the app. This feature will prevent all hardware buttons from leaving the app (except a hard reset initiated by holding both Home and Power).



Source: Hands-on: Securing iOS, pwning your kids with Apple Configurator 1.2