Can I backup a device to a Mac iTunes and iCloud
I have accomplished this by plugging it into iTunes, selecting "Back up to this computer" and hitting Apply. It performs a backup to my computer and then I change it back to Back up to iCloud. As far as backing up automatically, I'm not aware of a way to do that.

’Course, I mostly rely on iCloud, but should get in the habit of doing this a little more often just to keep a copy on my computer.