Accessibility Menu items no longer selectable under OS X Yosemite?
The menubar item in Yosemite no longer allows you to make direct changes to the settings, it is merely an advisory list of what is on and off.

You can make changes to the settings in the list below, previously accessible from the menubar, by pressing Option-Command-F5 and ticking the appropriate boxes (see screenshot). The remaining settings, and others, can be set in System Preferences.


Invert screen colors
Mouse keys
Sticky keys
Slow keys
VoiceOver