gpg-agent + launchd maxing out cpu overnight.. plus other stability oddness lately.. any ideas why?
My problems covered a few areas, but all stability seems to have been addressed.  

Regarding the gpg-agent issue, I haven't seen that come up again, and this maybe attributed to one of two things: 1) uninstalling Mozy; 2) keeping up with the OS X system updates.  I don't know which of these for sure, or if the issue is actually fixed, but several months later, I haven't seen this issue reoccur (Mozy was probably uninstalled a week or two after originally posting this).

Regarding the sleeping/freezing oddness, this may have been addressed by OS X system updates as well, or could have been related to this sleep issue I had with locking screen vs. going to sleep, detailed here: How do I stop my MacBook Pro from randomly freezing when trying to go to sleep?

As of this follow-up, I'm running 10.7.4.  Hopefully this helps someone else pinpoint a similar issue.