Apple Configurator 2: Apply Blueprint one by one
No, not with Version 2.1 (3B42) of Apple Configurator. There are some workarounds that come to mind:


You could make smaller groups and keep the same blueprints
You could determine the limiting factor in your MDM responsiveness and address that to handle 50 devices at once.
You could re-implement the blueprint in a script and have that script iterate over the group with delays that resolve the bottleneck.


It really depends on what you are doing. If you cannot add a simple blueprint that adds one Web Clip to all 48 devices, then you might need to rethink your MDM or infrastructure. I'm having a hard time imagining something that saturates a link to MDM since they generally are quite efficient and just transfer configuration data and not loads of document data.