Safari can't connect to localhost
Edit: this didn't help, ignore it.

This might be related to HSTS. Different browsers deal with it in different ways. Do you have any non-Apache local web server installed? I'm assuming there's something to do with Focus that's running on port 8919 from your screenshot.

Try this: Quit Safari, make a backup of ~/Library/Cookies/HSTS.plist somewhere safe, delete ~/Library/Cookies/HSTS.plist, start Safari, and try that URL again. Does that help?