How do I fix my video and audio on mac
If you're indicating that you're in Safe Boot and your audio is not working on the built-in speakers of your Mac... that's expected. Safe Boot is a testing environment only and some things simply do not function there due to the imposed limitations of Safe Boot, for the purpose of testing.

If Safe Boot fixed your primary issue, then simply restart. If the issue is still resolved, then hooray. If not, then you have something causing an issue in at least one of the following locations: Launch Agents, Launch Daemons, Startup Items, or Login Items.