How do I disable the Command-Control-D word definition keyboard shortcut in OS X Lion?
To disable the Control-Command-D binding enter the following in the terminal:

defaults write com.apple.symbolichotkeys AppleSymbolicHotKeys -dict-add 70 '&lt;dict&gt;&lt;key&gt;enabled&lt;/key&gt;&lt;false/&gt;&lt;/dict&gt;'


and restart.