Exchange clipboard only with a virtual machine running in Parallels 14
Clipboard sharing should not be affected by the "Isolate..." selection.  Check Options > More Options in the VM configuration to confirm "Share Mac clipboard" is enabled. 

That being said if you want to disable the "Isolate..." option, the individual sharing settings are distributed in several locations.  Shut down the VM first as deselecting the "Isolate..." option immediately re-enables the sharing features while VM is running.  

Here are various sharing configuration locations that I am aware of, but I suggest looking through all the sections to be sure I haven't omitted some.  


  Options > Sharing
  
  Options > Applications
  
  Options > More Options
  
  Hardware > Printers
  
  Hardware > Sound &amp; Camera
  
  Hardware > USB &amp; Bluetooth