MacOS Calendar App - Default reminders
Not that I know of, but there's a potential workaround - I don't know whether this would be any use to you.


Make a new event, call it myDefault, set all your reminders as you want them to be.
Any time you make a new event, start typing myDefault - it will auto-suggest that previous entry, but at the date you double-clicked. It will fill it with the previous data, shifted to the new time. 
Accept it, then change its name.


You can set several of these, named appropriately - the one thing you can't do is dictate which calendar group they belong to, so you'd have to make sure to generate the name to match the group it's going to belong in manually.