Periodic Backups to a remote Windows Server folder with OS X
If the remote (Windows) filesystem is mountable in the Finder than any application that does file level backups should work. I use SuperDuper and have used Carbon Copy Cloner and Chronosync in the past with good success. 

Note that CCC backs up to either a Mac filesystem or a DMG (disk image) file which may be problematic on a Windows PC with no Macs around.