Cannot repair permissions on systemsetup (open error 1)
It's possible that this is a message that you can safely ignore.

There is an Apple KB article for OSX versions 10.6 and below that itemises those error messages that can be ignored, however that message is not in the list.  I cannot find an updated KB article for 10.7.

If the message does concern you, I'd suggest you reboot and hold down the Option key, you can then enter into Lion's Recovery mode from the menu shown and see if that does the trick.