Can the iPad support multiple Regional Settings simultaneously?
You can have multiple keyboards enabled: Settings -&gt; General -&gt; Keyboard -&gt; International Keyboards. Add whichever keyboards you wish. Then, when you are typing text, hit the globe key on the keyboard to switch between the different keyboards.

As far as I know, you can't have multiple languages enabled at the same time for spell checking. However, you can switch between them using Settings -&gt; International -&gt; Language.