`dtrace_deadman_timeout` modification for dtrace scripts such as dtruss?
I've had the same issue. I don't know if it's encouraged, but you can use the "-w" flag to "allow destructive actions." This seems to have fixed the issue for me. However I have no idea what the consequences are. I'm running a very simple script though, so I'm reasonably confident that I'm not doing anything that is very "destructive."

This was hard to find, it was a pdf of slides of a presentation given on dtrace and I get the feeling that MacOS only begrudgingly allows basic DTrace support these days. This is too bad because DTrace is an incredibly powerful tool.

For the sake of any poor soul who wanders here with similar issues, the official DTrace book is really helpful and while it doesn't have all the answers, it has probably most of them.