Moving files >4GB from a Mac to a Windows box
If you are under 10.6.5 or later and Windows Vista or above, you can format your memory stick or usb hard drive to exFAT, a newer version of FAT with large file support and almost unlimited partition size. It has no permissions to speak of so it's perfect to transfer files around.

Older systems will not see it however.

I use this file system on my external 1TB WD hdd and it works beautifully.