Automatically hide notifications from Notification Center while in fullscreen
This isn't a perfect answer, but it's a smooth workaround.  In System Preferences > Keyboard > Shortcuts > Mission Control you can map a keyboard shortcut to "Turn Do Not Disturb On/Off."  I chose command shift spacebar as I believe it does not overlap any default keyboard shortcuts and it's similar to activating Spotlight.  Now I simply hit those keys to quickly hide and show notifications.