Safari (6) and HTTPS
Not at the moment. According to the HTTPS Everywhere FAQ:


  Q. Will there be a version of HTTPS Everywhere for IE, Safari, Opera, or some other browser?
  
  A. Some members of our developer community are working on an IE port of HTTPS Everywhere. As of early 2012, the Safari extension API does not offer a way to perform secure rewriting of http requests to https.


Source: https://www.eff.org/https-everywhere/faq