Remap Ctrl+C, Ctrl+V, and Ctrl-X only
One option would be to use DefaultKeyBinding.dict, but it wouldn't work in all applications or text views.

{
    "^x" = cut:;
    "^c" = copy:;
    "^v" = paste:;
}


KeyRemap4MacBook would work almost everywhere, and it also allows excluding specific applications.



Here's the definition of the remapping selected in the screenshot:

&lt;item&gt;
  &lt;name&gt;Use PC Style Copy/Paste&lt;/name&gt;
  &lt;appendix&gt;(Control+C to Command_L+C)&lt;/appendix&gt;
  &lt;appendix&gt;(Control+V to Command_L+V)&lt;/appendix&gt;
  &lt;appendix&gt;(Control+X to Command_L+X)&lt;/appendix&gt;
  &lt;appendix&gt;(Except in Terminal, VM, RDC, Emacs, X11, Eclipse)&lt;/appendix&gt;
  &lt;identifier&gt;remap.copy_paste_winstyle_no_term&lt;/identifier&gt;
  &lt;not&gt;EMACS, TERMINAL, VIRTUALMACHINE, REMOTEDESKTOPCONNECTION, X11, ECLIPSE&lt;/not&gt;
  &lt;autogen&gt;--KeyToKey-- KeyCode::C, VK_CONTROL, KeyCode::C, ModifierFlag::COMMAND_L&lt;/autogen&gt;
  &lt;autogen&gt;--KeyToKey-- KeyCode::V, VK_CONTROL, KeyCode::V, ModifierFlag::COMMAND_L&lt;/autogen&gt;
  &lt;autogen&gt;--KeyToKey-- KeyCode::X, VK_CONTROL, KeyCode::X, ModifierFlag::COMMAND_L&lt;/autogen&gt;
&lt;/item&gt;