Change from Mac OS Extended File to APFS in order to install Mojave
The internal drives of Macs are converted to APFS when upgrading to macOS 10.14 Mojave and yes, macOS Mojave boots from APFS just fine.

More specifically, when Mojave is installed it will convert any internal drive (including SSDs, HDDs and Fusion/Hybrid Drives) from HFS Plus to APFS. 

This is an important distinction as prior to macOS Mojave, only SSDs were converted to APFS, and this explains some of the confusion over time regarding how macOS Sierra, macOS High Sierra and macOS Mojave have managed things as APFS has continued to evolve.