Macbook pro crashes Whenever installing Matlab 2016?
You never mentioned which version of MATLAB you were running.  However, the 9.0 (R2016a) doesn't mention Sierra at all and the R2016b which does list Sierra support has it as "limited."  

First thing I would do is verify that your version of MATLAB is compatible with Sierra.

Secondly, a read error is indicative of a drive error.  It could be a corruption of the file or it could be a physical error.  You need to at least run First Aid on your drive to see if there are any problems.