Set page for PDF to open to
No. Preview does not respect the PDF Initial View metadata. Other Readers, such as Skim and PDFPen Pro, also do not. Instead, all of these apps open at page 1 and then remember the last page viewed for the next time the document is opened. Foxit Reader does respect the Initial View.

Your best solution is to provide a Table of Contents (aka Bookmarks, Outlines), so that users can easily click to the desired page.

It's worth noting that Preview's own 'Bookmarks' are not PDF-standard, and will not be displayed by any other PDF Viewer.