Can I delete files or folders from /private/var/folders/?
You can safely delete anything in /private/var/folders/ but not the folder itself
sudo rm -rf /private/var/folders/*

Quit all apps before you do &amp; reboot afterwards … and whatever you do, don't touch anything else in /private/var/, and do not delete /private/var/folders/ itself.

Rumor has it that one should not delete /private/var/folders/zz. This article implies otherwise, but if you want to be on the safe side, use
cd /private/var/folders
for i in *; do if [ &quot;$i&quot; != &quot;zz&quot; ]; then sudo rm -rf &quot;$i&quot;; fi; done
sudo rm -rf zz/*

instead.