Text-To-Speech to read websites in Chrome?
OS X's built in screen reader, VoiceOver, works in Chrome.

To enable it, go to System Preferences-> Universal Access-> Seeing and toggle the VoiceOver: radio group to On. You will also be able to check the shortcut key for easily enabing/disabling VoiceOver.

I recommend you take some time and familiarize yourself with VoiceOver; it's very powerful but takes some getting used to.

Click the VoiceOver Utility button to configure VoiceOver. This lets you change, among many other options, the voice and speaking speed.