Remove the Notification Center icon from the Menu Bar
So you can easily disable it with

launchctl unload -w /System/Library/LaunchAgents/com.apple.notificationcenterui.plist; killall NotificationCenter


You can remove the icon with

sudo rm /System/Library/CoreServices/SystemUIServer.app/Contents/Resources/menuitemNormal.pdf 


but the blank space will remain.  There is an app called Bartender I've seen a few people promoting to fix this issue.