Best approach for enterprise integration
While Apple puts their iOS Enterprise Deployment documentation in their developer area, it doesn't mean that you need custom software to handle iPhones and iPads. It's all pretty much what I think of as standard sysadmin-type work, so while it does require some knowledge of XML files and scripting, it's fairly well documented.

Here are some places to start:


iPhone Configuration Utility 
Distributing Enterprise Apps for iOS 4 Devices
Over-the-Air Profile Delivery and Configuration
iPhone Configuration Profile Key Reference