high power - overvoltage protection
Please Look at the following picture

https://eenews.cdnartwhere.eu/sites/default/files/images/01-edit-photo-uploads/2012/2012-03-march/linear-technology/fig-3a.jpg
inside the link
http://www.eenewsautomotive.com/content/high-voltage-surge-stoppers-ensure-reliable-operation-during-power-surges/page/0/1

A circuit based on LTC4366 with proper changes could do the job for you.
Moreover the circuit could make the output open by proper triggering the SD input.