How to speed up level shifter?
I think this'll work.  Don't start out trying it with expensive hardware.  R4 and C1 are guesses -- the smaller you make R4 the quicker it'll switch and the bigger the current pulse on the HV line.  If you're going to use it over a wide span of HV voltages (you cited 50V to 150V) then you'll need D1 -- choose something with low capacitance, but that'll still absorb the current pulse at the highest supply voltage.

I'd reduce R3, or parallel it with a series RC for speedup, with the resistor sized for that 10mA that your microcontroller pin will put out.







simulate this circuit &ndash; Schematic created using CircuitLab