Total capacitance of two sets of parallel capacitors and resistors in series.
I’m assuming you need to calculate the impedance between Node2 and ground. Well, this is not a purely reactance value, i.e. it has real impedance components due to the resistors. Calculate C1//R1 in series with C2//R2 and this is it.

X1 = 1/jwC1
X2 = 1/jwC2

Where j is the imaginary number.