Is anything wrong with my PCB?
*Change resistor for RESET pin to 10K.

*Add a 100nF cap between AREF and GND pin.

*Add 100nF capacitor between each VCC pin of your ICs and GND.

*Connect GND pin of USB to GND.

*Connect VOS of TPS62172 to VCC!!!!

*I can't find GPSTX label! where it should be connected!

*Connect LED1 to GND.


Your L2 has no value, it should be 33nH.


I think revise your design...

This maybe useful:
https://www.sparkfun.com/datasheets/GPS/Modules/Skytraq-Venus634FLPx_DS_v051.pdf