Colpitts not oscillating as expected
The resonant circuit includes the Power Supply. You must bypass that. Your SPICE simulation VDD source has ZERO impedance; on your protoboard, that battery or power supply are located some distance away from the transistor, and those long wires ---- 100 nanoHenry per 100 millimeter ---- cause Fresonant to be much lower than expected.

Again, place a 0.01UF cap with SHORT LEADS from top of L1 to GND.

Alter your layout so those leads are, in total, only 1cm long.

In a final circuit, use a Ground Plane, further reducing the VDD inductance.

EDIT The actual frequency of oscillation is 1/4 of the predicted 50MHz. That means the actual inductance is 4*4 = 16X higher than what is simulated. 16x 0.15uH is 2.13uH............which is about 2 meters of wire. 

At low frequencies, the 2N2222 may perform well. But at 50MHz?