differential to single ended output problem
Let's start at the beginning. The gain of the AMC1301 is 8.2x. The input signal range is + - 250 mV. Thus, a + -2 V signal is expected at the output.


If we needed the full range, the 3.3 V supply voltage would be little for the 4 Vpp signal. Then we need to use a supply voltage of at least 5V. However, a supply voltage of 3.3 V is sufficient to solve the specific task. The next problem is that the input voltage of the TLV2221 can be between 0 and 2V at a supply voltage of 3.3V.
The Vp signal exceeds this value.



So we definitely have to choose a different amplifier. Select the same one you used for the older similar task.

The input DC offset voltage determines our operating points throughout. The operational amplifier must be set so that half of the supply voltage is at output. (For maximum dynamics.) The input already has a 1 V offset voltage. To do this, approx. 0.5 V must be added plus (VREF). We will do this by building a divider from two resistors with a voltage of 550 mV and the internal resistance 10k Ohm:

Thus we got to the point where we created an asymmetric from the original symmetric signal: