PTH drill diameter do the IPC take the pin distance in account?
This is an indirect reference to the actual (for pay) IPC documents, but it appears it does not take pitch tolerances into account. 



Minimum Hole Size is calculated according to equations below:


Minimum Hole Size = Maximum Lead Diameter + 0.25mm (for Level A of IPC-2222)
Minimum Hole Size = Maximum Lead Diameter + 0.20mm (for Level B of IPC-2222)
Minimum Hole Size = Maximum Lead Diameter + 0.15mm (for Level C of IPC-2222)




There is some compliance in the leads even close to the body, and the ends are certainly not guaranteed to not be bent a bit, so it's not as important as you might think.