Differential to single ended circuit
It's one right way, assuming that the other characteristics of this circuit are acceptable in your application.

For example, the input impedance is relatively low, compared, say, to an instrumentation amplifier. But if your source impedance is low, it shouldn't be a problem.

It also requires careful resistor matching in order to achieve a high CMRR. But matched resistor networks are readily available, as well as amplifiers that have the resistors integrated right on the chip.



EDIT: My comments above were based solely on looking at the topology of the circuit diagram in your question. However, the amplifier you linked to, the AD8422, actually is an instrumentation amplifier, so that circuit diagram does not apply.