Multimeter not picking up a resistance
To easily test that the meter is working correctly:


Select the 200 Ohm setting, it is at the very bottom of the meter dial
Connect the black lead to the Black jack and the red lead to the Red jack  on the right side of the meter
Touch the two leads (red and black) together and watch the readout. It should indicate 0.01 or perhaps 1.02 or at least some reading. 


If the meter does not give you a value when you have performed these steps, then it is very likely that its fuse (inside the meter) has been blown. (mentioned above)
or the meter is not working in the Ohm setting anyway.

I have gone over these steps because you mention you expect a readings in DC and AC.

You will not get a DC or AC reading when using the meter on a piece of wire. You will get a reading on a piece of wire using the Ohm setting (providing the fuse is OK).