Crossing analog traces with power trace
It'll almost certainly be fine
Based on the comments, the analog signal is running from one opamp to the next. This means it has a low impedance source, so it will be quite robust.
It also seems the power supply comes from a linear regulator, which will tend to produce a low-noise power supply. As long as the loads are well decoupled, they won't introduce much noise either, so the power supply trace won't be carrying much noise.
Without a target to hit, it's impossible to say whether the noise it brings in will be too much. But based on the above, it will be very small, and there are likely to be other noise sources in the system which are (much) larger.