Using Python to control Brooks MFC Power Supply
The manual says under section 4:


  For operation of the application software it is required to have the Brooks
  Smart DDE software (version 1.1 or higher) running on the P.C.)
  Version 1.1 of Smart DDE can operate without the software protection
  key (dongle) when Interfacing with Model 0152/0154.


So I guess if you write a Python script that interacts with the Smart DDE you can communicate with the device. But their package is probably not for free...