High Voltage and Low Charge - Analogy (ESD & Lightning)
Like, If something has high voltage, does it mean that it has a lot of charges 


No, it means that a unit of charge holds a lot of energy. That's the definition of voltage: energy per charge.


  does it mean that it has less number of charges, charged to high potential.


It doesn't say anything about the amount of charge (charge isn't really countable, but you just mean "much charge").

Charge and voltage are only linked in certain physical objects (like capacitors), and then through the simple formula Q=CV you give in your question. There's really nothing more to it; you can't generally say "an object with high voltage always has low charge" or "… always has high charge" or anything.