MAX4544 in plain english
Relays give you some degree of isolation between the control signal and the switched circuit, so you don't have to care about things like ground potential differences or high-voltages on the switching side possibly appearing at the control input.

The MAX4544 does not provide that isolation. As an alternative, the IR PVT312 does provide the isolation you require because it's an opto-isolated MOSFET switch and is described by IR as a "HEXFET Power MOSFET Photovoltaic Relay".