Can't figure out schematics error
LM386 has a ground-referenced input according to its datasheet so you need an AC coupling capacitor ( 1uF or so will do; even 0.1uf unless you need bass!) between the DAC output and pin 3.

As it is now, if you have a meter, you will probably find Vout (pin 5) is very close to Vcc (5V) instead of Vcc/2 (2.5V).