Generate pulse when any of inputs changes
This will work, after some fashion.







simulate this circuit &ndash; Schematic created using CircuitLab

Caveats.

If two inputs change state at the same time, their XOR (parity) sum will not change.

The pulse-forming network is a bit crude. You would be better with a Schmidt input following the RC delay. A chain of a few spare gates is also a commonly used delay element, and cleaner than an RC.

If two input changes occur within the pulse length defined by the delay, the output will not be clean.

It may be better to configure the interrupt input to detect change of state (if that's possible) and omit the pulse-forming stage.