Could a modified sine wave inverter destroy/damage the AC adapter for a laptop?
&quot;Modified Sine&quot; outputs are very bad approximations of AC
This is a capture of the output of an APC 650 recorded by Jesse Kovach, while under load.

Notice the severe over-amplitude events at the extremes (the spikes at top and bottom). In reality they are actually much greater in amplitude, but the oscilloscope in the image was not fast enough to capture it.
Sharp edges in the time domain equate to broad-spectrum noise in the frequency domain. All of this high-frequency content represents additional energy that must be absorbed by protection circuits. If not, it can exceed isolation withstanding limits in the various input stage components and &quot;burn through&quot;. If this doesn't burn out the input it will result in a cascading failure where it will cause something to fail on the secondary side from the resulting overvoltage.
...and that's just one failure mode. There are others. Psuedo-sine waves are poor matches to sine-wave inputs. :(
Go DC-DC instead of DC-AC-DC
A much better (and much more efficient!) approach is to go DC-to-DC directly (note: you can't actually go DC-to-DC directly if your input voltage is lower than your output voltage, but the details of this are well contained inside a &quot;DC-DC converter&quot;).
Self-contained switch-mode power supplies for Dell laptops that take DC inputs are available in the marketplace. Here's an example:

which I sourced from:
http://www.amazon.com/Adapter-Charger-Dell-Latitude-D630/dp/B002BK7JEC#
Please note that I have no personal experience with this particular product and many cheap DC converters are poorly designed internally. Be careful.