PCB design for automotive fusebox?
The problem with PCBs in this application is two fold: 1) protecting the board from moisture (copper oxidises in the present of moisture) and 2) The current carrying capacity of the copper traces on the PCB. The copper layer on most PCBs is very thin and won't carry many amps of current. You could make the traces wider but almost certainly you'd have to either lay down copper wire on top of the traces and cover them in solder, or add a layer of solder onto the tracers all over to add thickness to enable the copper to carry the current.

Your best approach is to use fuse holders which have holes to mount them onto a flat surface and have screw fixings or solder tags for wires to be attached.

The moisture problem can be dealt with, using potting compound to keep out any moisture, but first off you need to deal with the problem of the copper layer on the PCB not being able to handle the current.