Reuse PIC serial pins
The output from the PIC to the FT232 can be reused for any purpose you like, provided that you don't care that the signal is also going to the FT232 and hence to a connected PC.

The other signal is an output from the FT232, so if you want to re-use it you must 'isolate' the FT232 in some way. My favorite is a 1k resistor. If you use the PIC pin as output this will add some extra load. If you want to use the PIC pin as input there is a problem: the other source must be disabled while in bootload mode. I don't think this is worth the trouble.