Help with this protocol - LCTC
Note that (unlike the LCD that you used via I2C) this is a typical controller-less LCD: it expects (needs!) a constant stream of data to work properly. 640x200 bits = 16000 bytes. Do you have that amount of RAM to spare? If so, the next problem is whether you can drive the signals at sufficient speed. Probably doable, but not easy. Might require assembly or very careful C/C++. Analyze the datasheet to find out how fast you must drive the LCD.

The M signal inverts the polarity of the drive to the LCD, to avoid a DC aspect in drive signal, which would destroy the LCD.