Best way to convert 5V DC to 110V AC at 50Hz for pdlc film drawing 2mA max. Size is the thing!
I would look into using a driver meant for electroluminescent wires and lamps ("EL Wires", "EL Lamps"). A while ago I rolled my own, using a MAX14521E. There are many companies making these driver ICs, and I expect that by now there may be appropriate off-the-shelf modules.

EL drivers are intended to drive a capacitive load with low current requirements. The "datasheet" that you have posted doesn't really say anything about how the load presents itself, although Wikipedia mentions that a PDLC structure "is in effect a capacitor."

The MAX14521E, to use as an example, is powered by 2.7-5.5 VDC. Its output voltage can be set (via I2C serial commands) from 0 - 300 \$V_{p-p}\$, and the output frequency is selectable from 50-800 Hz. It's a small chip, uses a tiny inductor (3 x 3 x 0.9 mm!), and no heatsinking is required.

That particular chip has four independent outputs, has dimming, automatic fade-in and fade-out, etc.

Different chips are able to drive varying loads.  Make sure that you choose an IC that has an appropriate output current capability!