Resistance or conductance of resistor networks
You certainly can use any simulator to determine transfer function or impedance.

For DC, put a current source and a voltmeter between the two nodes "in,out" at any value such as 1mA or 1A ( won't burn up a simulator, lol) 

By the way, this is how DMM's work in the resistance scale, and some change current scales e.g. from 100uA to 10mA for different R ranges.  Some precision RLC meters use Sine wave current sources, and others use pulse decay time constant method.

Req=V/I

The best tool is the one you can master easily then move up to a better tool.