Try to make a preamp guitar
Guitar pre-amps are usually designed with a high input resistance (typically 1M0). Your circuit has an input impedance roughly equal to the value of R3 which I suspect is somewhat lower than R4 probably by a factor of 10. Even at 150k it would be too low.



A better approach would be to use a non-inverting configuration for the op-amp such as.



The gain is set by R4 and R3  (Gain = 1 + R4/R3). The pre-amp has a gain of about 3. The input impedance is about 1M1 (2 x 2m2 in parallel). It uses a FET input op amp. 

Note this is only a pre-amp. It will not drive a loudspeaker or headphones. You need to take the output of this circuit into an amplifier capable of driving a speaker.