Checking my understanding of this datasheet of a TFT LCD display?
1) No. It's a pulsed input. From Figure 7.6.12, on datasheet, we can see that the pulse for RESX (pin 39) must be in low state for at least 10 us. Must be high for normal operation. Also, it's necessary to wait 5 ms after releasing the RESX pin before sending commands.

2) Depend. The CS signal (chip select) is used by i80 interface, but I think this same pin is renamed as SCEX when using the SPI interface.

3) Yes.