Effect of Isat on inductor when connecting four inductors in a combination
The saturation current is a constant for a given inductor. Just like the "normal" current will be shared between two paralleled inductors depending on their value, this "normal" current will just reach the point of saturation. In Theory, two parallel inductors can take twice the (saturation) current of one induvidual inductor. No big deal here. For series-connected inductors, it's a bit like the chain analogon: The chain breaks once the weakest link breaks. The behavior of two series-connected inductors is covered here.

Your setup of a series connection of two paralleled inductors each will have twice the saturation current compared to the value you find in one inductor's data sheet.

However, you will likely end up having your four paralleled and series-connected inductors close to each other. Depending on the type of core and the stray field your cores will create, your four inductors might become coupled to a certain degree, with the overall inductance not being what you expect. See here for more info on this issue.