5V Tolerant Way To Generate Rising Edge Signal on USB Connection
If a uP pin is "5V tolerant", it doesn't mean that you need to push the input pad to its maximim. A standard level (I assume it is a 3.3V uP) would be just fine to wake the uP up. Here is the standard circuit to handle VBUS connect event:



Anything "better" like a buffer or else will be an overkill.