i2c communication between cc3200 and at42qt2120
There is a very good chance that the problem that you are encountering is due to the chip thinking that one of the touch inputs is being continually activated over and over again. That would result in the CHANGE output getting set active no matter how many times you try to read status to clear it.

You could verify this by reading out the status bits for each touch switch input and seeing what data the chip presents about each one. 

As an additional test you could start by setting all keys to disabled state by setting bit 0 of each of their control bytes to 1. With all inputs disabled the CHANGE output should go inactive. Then enable each touch input individually one by one. That should allow you to locate which input(s) are causing the continual detection problem.

Once you know which inputs are causing the problem you can start the specific job of trying to understand why. It could be improper layout or bad connections. With touch type inputs it could also be coupling from other adjacent circuits.