Basic LCD drive question for Lumex
So for example, if this were ran off of an arduino, is there a better way to control the massive amount of pins?

Can't; you need a relatively specific control voltage, in an AC waveshape. Your Arduino simply hasn't got the hardware that makes that easy. (&quot;many pins&quot; means you'd need to literally switch a lot of pins at a relatively high rate, and that means Arduino-typical MCUs aren't the tool of choice – too few pins, too slow. Even if that weren't the case: you really want something specifically designed to drive LCDs, otherwise you'll just be burning power.)
You'll want a screen that includes that driver, or you want an external driver.