Panels - Style region to become a drop down/expandable menu
I solved this by using the following module &amp; some code:

http://drupal.org/project/panels_extra_styles

Panels region > Change style > Wrapper: raw.

Content prefix:

&lt;script type="text/javascript" src="/misc/form.js"&gt;&lt;/script&gt; 
&lt;script type="text/javascript" src="/misc/collapse.js"&gt;&lt;/script&gt; 
&lt;form&gt;
  &lt;div&gt;
    &lt;fieldset class="collapsible form-wrapper"&gt;
      &lt;legend&gt;
        &lt;span class="fieldset-legend"&gt;Attachments&lt;/span&gt;
      &lt;/legend&gt;
        &lt;div class="fieldset-wrapper"&gt;


Content suffix:

        &lt;/div&gt;
    &lt;/fieldset&gt;
  &lt;/div&gt;
&lt;/form&gt;


Save and update. Voila!

References: Supplied if needed.