Creating a vanilla instance from a site already set up
There are 2 easy options:


Use the Delete All Module and it's Drush interface.
If that's not thorough enough, I typically just end up using an SQL script to set foreign key checks to 0; and then truncate all fields, cache, revision, users, user_roles ... etc tables specific to my site. While it seems like alot of work it's basically a 1 time audit of the underlying DB for the script creation and simply tracking what new tables are needed for wiping when you add new modules. I've then used Rules_Link and the php filter to make this SQL statements runnable via a button press from a displaysuite panel ...