hook_view, hook_theme and Display suite
For people interested to the solution, you have to use the hook_field_extra_field() hook.

There you can declare your own "virtual fields" and they will appear as fields also in the Display Suite.

To link them to the content you create, just be sure to use the same name as a key both in the field name and in what you add as a node->content.

To provide you with the solution related to my example:

/**
 * Implements hook_field_extra_fields().
 */
function mymodule_field_extra_fields() {
  $extra['node']['my_custom_bundle_type']['display'] = array(
      'ds_column' =&gt; array(
        'label' =&gt; t('My column'),
        'description' =&gt; t('Description is also mandatory'),
        'weight' =&gt; 99,
      ),
  );
  return $extra;
}


As you can see ther key ds_column is the same used in the mynode_view (or in any other function implementing a hook able to modify the content render array).