Hide menu item in specific block/region
If I were you, I'd rather do this in my module code to access the links data:

function mymodule_block_view_alter(&amp;$data, $block) {
  if($block-&gt;title == 'myblocktitle') {
    $data['content']['#content'][idofthenodelink]['#access'] = false;
  }
}


And your link will no longer be accessible.

Here is the dpm($data['content']['#content']) after the operation: