Get a file URL from a custom entity referenced on a user profile
Solution:

$cv_wrapper = entity_metadata_wrapper('user', $user);
$cv_upload = array();
foreach ($cv_wrapper-&gt;field_cv-&gt;value() as $feature) {
    $cv_upload[] = $feature-&gt;field_candidate_cv;
}
$fid = $cv_upload[0]['und'][0]['fid'];


Printed the array of $cv_upload using:

drupal_set_message('&lt;pre&gt;'. print_r($cv_upload, TRUE) .'&lt;/pre&gt;');