How to update custom paragaph which is added to User Profile?
Don't save the paragraph, add it to the user field and then save it together with the user:

$paragraph = Paragraph::create([
  'type' =&gt; 'mmodule_paragraph',
  'field_employee_id' =&gt; 'Field value',
  'field_location' =&gt; 'Field value',
  'field_name' =&gt; 'Field value',
  'field_segment' =&gt; 'Field value',
]);
$user-&gt;field_paragraph[] = $paragraph;
$user-&gt;save();


In case you want to replace the field content overwrite the entire field array:

$user-&gt;field_paragraph = [['entity' =&gt; $paragraph]];