Overriding hook_menu() { $items }
Yes, you should use hook_menu_alter
Create new module and add hook_menu_alter

function my_module_menu_alter(&amp;$items) {
    // Unset core path
    unset($items['comment/%']);
    $items['your/pass/here/%node'] = array(
        'title' =&gt; 'Add new comment',
        ...
      );
}


But link "comment/reply/%nid/%cid" is used by Drupal for replies to other comments (where %nid - node id and %cid - comment id you are replying to). Use another path.