Drush enable/disable Devel modules
I prefer to have a custom module that has dependencies for all the developer modules I need. I also set up this module to have some strongarmed variables (such as turning off preprocessing of css/js and any page caching), and enables a few developer blocks using Context (such as execute php and context inspector). This allows you to simply drush en/dis the one module to turn on/off all of your developer utilities.

Here's my Lullabot devel module that you can look at for an example.