Can a solar system exist where the second planet rotates fast, and the third planet is tidally locked to their star?
The tidal locking timescale depends on several factors: $$\tau_{lock} \approx \frac{0.4 \omega_0 a^5 m Q}{3 G M^2 k_2 r^3}$$ such as the initial spin rate $\omega_0$, the semimajor axis $a$, the mass $m$, the solar mass $M$, the radius $r$ and various dissipation parameters $Q$ and $k_2$. 

Two planets that merely differ in $a$ will have the inner one lock much earlier than the outer one. But give them slightly different $\omega_0$, $m$ and especially $r$ and the inner might dissipate more slowly than the outer.

There is also the possibility of spin-orbit resonances. Mercury is in  3:2 resonance, and tidal forces might lock planets into 2:1 or 5:2 resonances. That way the inner planet may be in a resonant lock while the outer is tidally locked 1:1. In fact, Venus is turning very slowly (and retrogradely) so it is not too far off, although the causes of the retrograde spin are unclear. 

So, yes, you can have tidally locked planet orbiting outside non-locked planets.