how to calculate Pairwise Alignment Scores for blosum62
Your alignment is 


SDRVIKAAIFDPIQPDF---G-----PVYFGLGHVH
RDLVERLFILDMI-PGLIKAGDSFPIPVALMINHIF


For each position in the alignment you calculate the score for that alignment. For position 1 we'd look up S vs R in the matrix and find a score of -1. You continue doing this until you hit the first -, which is not in the matrix. The first - is a gapopening, each consequent - in a series of -'s counts as a gap extension, instead of an opening.

---G--
IKAGDS

gives
-12 -2 -2 6 -12 -2