RPGC normalisation creates artefacts at centromere
UPDATE

Here is some other protein ChIPs that I ran through the same normalisation:


As you can see, they don't seem to be enriched at the centromere. So unless anyone brings other contributions, I will accept this as answer.

RPGC normalisation doesn't appear to create artefacts at centromere. The peaks observed here are as real as can be.