Ultimaker Cura problems with build platform size and overhang support
Ultimaker Cura print bed size sizes (shrinks) when you enable skirt, brim or raft build adhesion options. Try to print without build plate adhesion option if you want to push printing to the limits of the build plate. Furthermore, you mention the use of PVA, using 2 cores, the priming print tower also needs space to be printed, this can be also limiting your build plate space. Note that you can define where to print the tower, you could try locating it in a corner where the fan does not reach.

From your screenshot with the fan flat it appears that you have selected dual extrusion. Note that the bed size depends on the amount of cores you use, from Ultimaker:


  Left or right nozzle: 215 x 215 x 300 mm (8.5 x 8.5 x 11.8 inches)
  
  Dual extrusion: 197 x 215 x 300 mm (7.8 x 8.5 x 11.8 inches)


As an example I have made a 7.44" cylinder of 2" height and put it onto the UM3E build plate to show the differences when you use dual extrusion.

This image shows the cylinder when printed with a single core:


This image shows the same cylinder, but now with enabled "Extruder 2" as the "Support Extruder" option:




Having an Ultimaker 3E myself, printing PVA might not be very good choice as you need to print a lot of support material when printing upright. PVA cooks easily even in the B core, it also needs to be very dry, PVA takes up moisture very fast and becomes useless after that. At work we have much better experience with break-away support material.

Another consideration why you should not print this upright is the orientation of the layers. It is generally known that the layer to layer bonding is less strong that the material itself, it at least provides a lot of notches from which cracks can initiate and grow. This means that if you want to print this, you should lay it flat, this way the centrifugal force is in line with the layer deposition direction.



With the correct layer height (read thin layers), you should be able to print this flat without support. I have printed similar structures like turbo turbine wheels with similar overhangs without support.