Creality CR-10 problems with extrusion while printing
Clearly you're having an extrusion problem. Extrusion problems usually come either from a clogged nozzle (as @Adam S. said) or from the extruder it self. To determine where the problem is located I would first do a flow rate test using this. When doing this test you can determine if the extruder is grinding the filament or if it's not grabbing it too much. After the calibration of the flowrate you can be certain that the printer is (by .gcode) pushing the correct amount of filament. If the problem persist I would first do an unclogging (since it's cheaper than the following option) using something like this. 

If both previous options do not solve the problem, I would highly recommend you to by a mk-8 like metal extruder. After a while, the plastic one that comes with the printer loses force and you'll lose steps. Personally, I had a similar problem where the first layer was printed in a droplet pattern and was solved by changing the extruder to a metal one.

Try these options and if the problem persist you could upload some pictures of the first layer or a video. Other possibilities I think of are that the filament is having trouble passing through the Bowden tube or maybe you'll have to reasemble the hotend.