Is the Circuit Possible?
Python 3, 253 bytes

import functools
def p(l): return functools.reduce(lambda z,x:z+[y+[x]for y in z],l,[[]])
print(l[-1:][0]in[round(a)for a in[sum(a)for a in p([sum(a)for a in p(l)]+[1/sum(c)for c in[[1/b for b in a if b!=0]for a in p(l).copy()]if sum(c)!=0])]])


I take the powerset of all resistor values and then calculate the sums for series and 1/sum(1/values) for paralel and then I take a powerset of these two sets. When you take the sum of all the subsets and put them into a set then this set eiter contains the value or not. -> return True/False

@stephen thanks :)