Can a simulator (FFS) be used in place of a Technically Advanced Aircraft (TAA) to meet the commercial experience requirements?
You can't use a simulator for this time because the regulation specifically requires training time in an airplane; there's no mention of using a simulator. If you look at some of the wording in the currency regulations in 61.57 (for example) you can see that when the FAA allows you to use  a simulator they state it explicitly:


  The takeoffs and landings required by paragraph (a)(1) of this section
  may be accomplished in a full flight simulator or flight training
  device that is [...]
  
  A pilot may accomplish the requirements in paragraph (c)(1) of this
  section in a full flight simulator, flight training device, or
  aviation training device provided [...]