What is the difference between MMEL and MEL?
The Master Minimum Equipment List is issued by the manufacturer with the approval of the regulator and can be considered a &quot;global&quot; document you might say.  The manufacturer will work hard to build the mathematical case to make the requirements as broad and flexible as it can. It's an ongoing process, and as the type is introduced and matures, the OEM will continue to increase the scope of the MMEL, because each new item added improves Dispatch Reliability (because more more and more components and subsystems can be inop without needing to be fixed right away).
The MMEL is the foundation for the Minimum Equipment List that the airline uses.  The MEL is an in-house document created by the airline and approved by the local authority.  It'll be based on the MMEL but may have additional limitations imposed by the local authority as it deems necessary for that operation.
It's similar to the Maintenance Program. The OEM will issue a Maintenance Program for a given aircraft type, but each airline will have its own variations by negotiation with its local authority.