Do aircraft engineers take into consideration engine placement to avoid ground strikes in a cross-wind landing?
For jet aircraft, there is no rule about preventing a nacelle from contacting the ground before the wingtip. There will be a design requirement that the airplane can touch down at a certain angle of bank and have the landing gear touch down but not strike a nacelle or wing, but not whether nacelle or wing must strike first. The nacelle is already designed for a wheels-up landing, so it's possible it could survive better than a wing tip. While it's certainly more of a risk on 4-engine aircraft, it can also happen on twin jets.

Propeller aircraft are typically designed such that gear and wingtip will make contact without the propeller making contact, either through having gear directly below props on a low-wing configuration, or through a high-wing configuration. While a jet engine nacelle can sustain some structural damage in a strike, it will typically not affect the engine's operation. If a propeller gets damaged it could cause that engine to become unusable, making it much more difficult for the crew to successfully perform a go-around.