Can a VFR flight reference a waypoint in communication?
J. Hougaard is correct. With Tower, Approach and Center, yes you can use waypoints in communications. Be prepared for them not to know immediately where a lesser used waypoint is. I have had Center not know where particular Class G airports in their jurisdiction were. Some know the names by heart, but not the airport codes.

When it comes to communicating with FSS, best practice is to reference your position by distance and direction from a VOR. Especially on your initial call. If you are on a flight plan, reference the points in your flight plan. Referencing an airport will also work.

When communicating over CTAF, it is best not to use waypoints. Instead, use distance and direction from the airport. Even if you are flying IFR or you are on an IAP. Otherwise reference your position by very well known Visual Reference Points. Preferably ones that are charted on your sectional. There are a lot of non-instrument rated pilots who may also be flying. A waypoint may not mean anything to them. Lack of ATC will mean lack of separation control unless you communicate in a way that is universally understood using the lowest common denominators.