Could the Space Shuttle take off like an airplane?
Despite the scene in Moonraker the Shuttle orbiter carried no fuel for the main engines.

Further, the orbiter sat nose down on its landing gear, lacked the elevator authority to raise the nose off the ground at landing speed, and could not retract its landing gear (it used a straight-fall gravity deployment).  The OMS didn't have enough thrust or delta-V at sea level to accelerate the orbiter from a stop to flight speed, even without the pitch authority issue.