Can we eliminate the center tank of large passenger planes?
I'm assuming you're talking passenger safety in the event of a ground impact - if anything happened midair, it wouldn't really matter if it were in the fuselage or one of the wings.

Moving the fuel somewhere else is going to have center of gravity implications. Moving it to wing pods or lager nacelles in particular would increase drag, which would require the plane to have even more fuel on board, which seems counterproductive to decreasing the fuel risk to passengers (and, of course, would substantially increase the cost of operating the flight).

Some military aircraft do carry fuel in removable underwing fuel pods (particularly fighters being ferried somewhere, where increased endurance/time between refuelings is more important than performance for that particular mission). However, that's less a safety design and more the lack of anywhere else to put the extra fuel on a small aircraft.

If an engine fails, the rate of fuel consumption is going to be different on each side of the plane. Although both are rare, you likely have far more situations where different wings use fuel at different rates than situations where having fuel feed under the body would be dangerous. If that's true, then removing the cross-feed line would be more dangerous than leaving it in.