Do two of the same model of aircraft feel different to fly?
In larger aircraft being flown by airlines that buy their airplanes from the carriers that originally bought them from the manufacturers, this can be a real problem. For example, Boeing used to allow considerable customization of 747 cockpits. For example, the forward cockpit overhead panel of 747-100 and -200 aircraft made for TWA had the switches reversed from all other purchasing airlines. The panel was at an angle, neither vertical nor horizontal. TWA treated it as a logically horizontal panel in that if you wanted a switch on, you moved it forward. All other airlines treated it as a logically vertical panel in that if you wanted a switch on, you moved it up. Thus, from the pilot's point of view, to turn on a switch on a TWA airplane, you moved the switch in the reverse direction of the other airplanes. Things got especially bad when switches from, say, an ex-Pan Am airplane were put in an ex-TWA airplane. Towards the end of my career (retired 1999), if I was in an ex-TWA airplane, I always looked directly at an overhead panel switch before throwing it. The differences section of the QRH (Quick Reference Handbook) of both 747 carriers I flew for was lengthy.

As I remember, the FAA finally stepped in and required Boeing to offer less cockpit customization.