Can Android Tablet can work on Windows 10 like Wacom Tablets?
The answer is a combination of YES and NO. You can use your android tablet to simulate a secondary display, and control it using the touchscreen. Twomon (http://www.easynlight.com/en/twomonusb/) is a software that I personally use to connect my tablet to my computer as use it as a secondary display. Twomon  works over USB, so you don't need any additional hardware adapters to get it working.
However, graphic tablets, like Wacom are built for precision drawing, and general-purpose tablets are not. So, I am not sure that this makeshift solution would be as effective as a Wacom (or other) graphic tablet.