Using the bone from a spiral cut ham
If it's a "ham" it's already fully cooked, so there is no danger in eating any part of it. If it's a leg of pork, that's a wholly different animal: different texture, flavor, everything, and...not to belabor the point...it's raw.

That being said, you can lump all the bones in the pot together, no problem. You'll get better results though if you cook the raw bones for a while in the oven first: 425 for ~15 minutes, or until they start to brown a bit. Not only will you lose a little fat, but the crispy carcinogens of the maillard reaction will add more body to your stock.