Can I use Bisquick instead of All Purpose Flour?
You cannot directly use Bisquick in place of AP flour.

According to the company web site and Wikipedia, Bisquick consists of bleached all-purpose flour with several other ingredients, including fat (shortening), leavening (baking powder), sugar, and salt. It is essentially a self-rising flour with added fat. Because of all of the extra ingredients, it will not behave the same as regular all-purpose flour. 

Depending on the recipe or application, you may be able to substitute or remove some of the other ingredients to make use of a pre-mixed flour like Bisquick.