Is it possible to HTTP inside an ISR
No, you cannot do HTTP in an interrupt, and you certainly can't use SoftwareSerial in an interrupt.

To trigger a heavy task in an interrupt you just set a flag (variable) which means "this task is due to be performed". Your main loop then checks that variable, runs the task, and resets the variable ready for the next time the interrupt triggers.

In multithreading environments these flags are called semaphores (yes, from the old signalling system using flags on ships). One thread (the interrupt) signals to the other thread (loop()) that it can do something.