5V usb surge protection for circuit board?
A polyfuse will limit current not voltage.

There are transient protection diodes which switch on if voltage exceeds a given level, which are often used in conjunction with a polyfuse. The diodes cause excessive current to flow, effectively turning on the polyfuse for extended overload, or just absorbing shorter transients. The Raspberry Pi uses a SMBJ5.0A device to suppress transients.

You should NOT need any of this if you use a reasonable power supply.