flash read err, 1000
Your PCB is lacking in the majority of things you need to get the module working. These modules are not "simple" in that you provide power and forget about it. You must add all the required support components. Those support components are NOT optional. For example: you aren't setting the boot mode properly with the right pullups. You lack a capacitor on the power pins (I told you to add one already. Where is it?). Also your power traces are too thin. The impedance is too high.