Best way to detect tilt using MPU 6050
Well suppose you have a starting position, let's say 0 degrees, then once you detect and angle change, let's say 10 degrees, you know that there is a tilt of 10 degrees on one of the 3 axies.

The MPU6050 is a 6DOF, meaning 6 Degrees Of Freedom. This means that it can detect acceleration on axis: x, y, and z and it can detect gyro angles on axis: yaw, pitch, and roll.

For the best accuracy, use a mix of both acceleration and the gyroscope. This is the best way to calculate position. Heck, the Apollo space program used a gyro and accelerometer to navigate from planet Earth to the Moon.