Arduino Mega 2560 bootloader delay
Yes.  You remove the bootloader completely and program the Arduino using a hardware programmer.

If you could "turn off" the wait period you would never be able to get into the bootloader to program the board, so the bootloader would be completely useless.  So either way you would then need a hardware programmer to do anything constructive with the board.

A hardware programmer could be another Arduino, or a real hardware programming adapter.