Two player tic tac toe Python
Input
One thing I would suggest is provide a hint to the user about the format of their coordinates input. It's not immediately obvious that the format should be x y. I had to look at the code to figure that out. Intuitively, one might expect to type in x and y on separate lines or maybe separate them with a comma.
One way to deal with this is to add a string in the input function, so rather than:
ordinates = input()
you could do something like:
ordinates = input(&quot;Please enter your coordinates (example: 1 2): &quot;)
Better yet, it would be easier to deal with only individual x and y coordinates throughout the program, rather than  mixing them with strings combining the two. For this, you would simply ask for the two coordinates with separate input() statements (e.g. input(&quot;Enter your x: &quot;, input(&quot;Enter your y: &quot;)). Then you don't have to worry about splitting strings or unpacking tuples or anything or the sort.
Coordinates
Another point is that the vertical coordinates seem to be backwards, in that the 1st row is at the bottom and the 3rd row at the top. Again it would make the game more user friendly to either specify this to the user or rearrange the grid array so that [1, 1] is top left and [3, 3] is bottom right.