Generic Null/Empty check for each property of a class
First of all I'd reduce indentation. It makes your code really too hard to read. Doing that you will see it may be simplified.

First of all try/catch: a catch-all block where you rethrow the exception is useless (and you may even throw away line number information.)

This code:

if (obj != null)
{
    // Do something...
}


May be replaced simply with:

if (obj == null)
    return false;


You do not need to declare a local variable for result, simply return its value where appropriate.

You do not have to check condition result == false inside your foreach loop (you will still enumerate through all properties), simply break the loop and exit immediately.

You do not need to use to dynamic, when casting you have the right type at compile-time. Also move all this code inside a separate function:

private static bool IsNullOrEmpty(object obj) {
}


Let's see how to fill this function. Let's read the value of the property:

object value = pi.GetValue(obj);


First of all a common case, valid for all reference types:

if (Object.ReferenceEquals(value, null))
    return true;


Then explicitly check for strings:

if (value is string &amp;&amp; String.IsNullOrEmpty((string)value))
    return true;


For Int32 (note that in your original code value &lt;= 0 ? true : false is redundant it may be simplified to value &lt;= 0). BTW are you sure you want to consider negative numbers as empty values?!

if (value is int)
    return ((int)value) &lt;= 0;


Boolean does not need to be checked in this case (null case has been already handled). We just need to work out Guid:

if (value is Guid)
    return ((Guid)value) == Guid.Empty;


That's all. Note that now or in future you may want to check for Nullable&lt;T&gt; and or other types. With the exception of strings and negative integer numbers you can also do something like this:

if (Object.ReferenceEquals(value, null))
    return true;

var type = value.GetType();
return type.IsValueType
    &amp;&amp; Object.Equals(value, Activator.CreateInstance(type));


What left in your original function? In this example let me use simplified check (negative numbers are not empty and I do not check for String.Empty against strings however it handles nullable types), feel free to pick the one works for you:

public static bool IsAnyNullOrEmpty(object obj)
{
    if (Object.ReferenceEquals(obj, null))
        return true;

    return obj.GetType().GetProperties()
        .Any(x =&gt; IsNullOrEmpty(x.GetValue(obj)));
}

private static bool IsNullOrEmpty(object value)
{
    if (Object.ReferenceEquals(value, null))
        return true;

    var type = value.GetType();
    return type.IsValueType
        &amp;&amp; Object.Equals(value, Activator.CreateInstance(type));
}


Last note: if working with databases you may also want to check equality with DBNull.Value.