How can I sync the Drupal User Profile image and the CiviCRM contact image?
I am not sure how to sync drupal profile image with CiviCRM contact image through UI. But you can add module and invoke hook to update the contact image.

Here is the snippet how to add image url to contact

$params = [
  'contact_id' =&gt; 2,
  'image_URL' =&gt; [
    'name' =&gt; '/var/www/html/drupal/sites/default/files/civicrm/custom/Screenshot_from_2018_06_19_15_46_08_1877c5451ed2e68a12816071e0006fef.png',
    'type' =&gt; 'image/png',
  ],
];
CRM_Contact_BAO_Contact::processImageParams($params);
civicrm_api3('Contact', 'create', $params);


HTH

Pradeep