AMAZON SES Rate Limit Question
I've used Amazon SES for a similar sized mailing list to you for a client.  I was confused initially and then surprised when they gave me a 14/s send limit.

However, when you work it out that's just over 50,000 per hour so the only issue is how to keep below the 14/s limit.  Well, as you've mentioned, CiviCRM has the very helpful "Throttle Time" which you can set to 75000microseconds to limit the send rate from CiviCRM to just under 14/second.

The client has found SES to be extremely fast and reliable. Just make sure you've got access to your DNS so you can configure necessary DNS entries to allow SES to send email for you.