Call to undefined function civicrm_initialize() in sites/all/modules/contrib/civicrm_entity/civicrm_entity.module:488
I'll guess that you've got a server with insufficient php or mysql configuration, and that in the process of your upgrade, civicrm was disabled for one reason or another.
You can probably just use sql to re-enable it with something like:
update system set status = 1 where name = 'civicrm'

And then use drush to clear all your caches.
The origin of your issue could be one of these settings in php:
post_max_size
max_input_vars
or the mysql configuration of
max_allowed_packet