Keeping CiviCRM invisible to end users
I can't think of a down side to the CiviCRM "base page" existing on your WordPress install - other than that you can't use that page for public-facing content. Anyone visiting that page will see holding text, not CiviCRM content of any kind. Viewing CiviCRM content requires query strings to be appended to the "base page" URL plus the appropriate permissions.