CiviCRM has not bootstrapped sufficiently to fire event "hook_civicrm_alter_drupal_entities"
This looks like a change in 5.29. See https://github.com/civicrm/civicrm-core/pull/17831. It's signalling that somehow something isn't working with the way either the civicrm_entity module is setting the hook now or something about that change isn't working as expected. I'm not sure which.