Contribute Page with a Profile in Edit Mode - Not Create Mode?
You can do this by adding &amp;cid=0 to the end of the donation page URL.  E.g. if your page URL is:
http://example.com/civicrm/contribute/transact?reset=1&amp;id=1

Instead use:
http://example.com/civicrm/contribute/transact?reset=1&amp;id=1&amp;cid=0